RELATIONSHIP BETWEEN TREATMENT ADHERENCE AND PROGRESSION OF DIABETIC NEPHROPATHY

In 2006, the Indonesian Renal Registry (Pernefri) shows about 12,5% of people in Indonesia suffer from chronic kidney disease. The most common cause of chronic kidney disease in 2018 in Indonesia is 39% by renal hypertension and 22% by Diabetic Nephropathy. This cross-sectional study was conducted at "RT" Hospital in Jakarta from 2018 to 2019. The Independent variable in this research was comorbid hypertension and obedience treatment, whereas dependent variables were risk category for kidney deterioration progression and the causal relationship tested with Pearson Chi-Square and Fisher exact as an alternative test. The study included 26 respondents, with 17 (65.4%) patients having hypertension in diabetic nephropathy. Eighty percent of respondents who did not routinely seek treatment in the hypertension group had progression from kidney failure to the Deep Red (Highest Risk) category. Fisher Exact statistical test analysis in the group with a history of comorbidities in the form of hypertension found no significant relationship between non-routine treatment with the progression of chronic kidney failure in the Highest-Very Highest Risk category (p-value = 0.515). Still, a large risk was found in the non-group routine treatment with a chance of 1.33 (0.962 - 1.848) times to have the progression of chronic kidney failure in the category of Highest-Very Highest Risk. Can be concluded that controlling blood pressure and treatment proven to slow worsening kidney function in nephropathy diabetic, even though no significant relationship has been found due to lack of sample. Keywords: diabetic nephropathy; hypertension; prognosis AbstrakPerhimpunan Nefrologi Indonesia (Pernefri) tahun 2006 merilis data penderita gagal ginjal kronis di Indonesia sebesar 12,5%. Etiologi terbesar gagal ginjal kroniks menurut Indonesian Renal Registry tahun 2018 adalah penyakit ginjal hipertensi sebesar 39% dan nefropati diabetic sebesar 22%. Potong lintang pada pasien di RS”RT” Jakarta tahun 2018-2019. Variabel bebas dalam penelitian ini adalah komorbid hipertensi dan kepatuhan berobat, sedangkan variable tergantung dalam penelitian ini berupa kategori risiko progresifitas perburukan ginjal serta hubungan sebab akibat diuji dengan Peason Chi Square dan uji alternatif Fisher Exact Test. Penelitian berlangsung mengikutsertakan 26 responden, dengan prevalensi hipertensi pada pasien nefropati diabetik sebesar 17 (65,4%). Delapan puluh persen responden yang tidak rutin berobat pada kelompok hipertensi memiliki progresifitas penyakit gagal ginjal hingga kategori Deep Red (Highest Risk). Analisa uji statistik Fisher Exact pada kelompok dengan riwayat penyakit penyerta berupa hipertensi didapatkan tidak hubungan yang bermakna antara tidak rutin berobat dengan progresifitas penyakit gagal ginjal kronis kategori Highest-Very Highest Risk (p-value = 0,515) tetapi secara besar risiko didapatkan bahwa kelompok yang tidak rutin berobat memiliki risiko 1,33 (0,962 – 1,848) kali untuk memiliki progresifitas penyakit gagal ginjal kronis kategori Highest-Very Highest Risk. Dapat disimpulkan bahwa engontrol tekanan darah dan rutinitas berobat dapat memperlambat perburukan fungsi ginjal akibat komplikasi lanjut dari nefropati diabetikum, walaupun belum didapatkan hubungan yang bermakan dikarenakan kurangnya besar sampel pada penelitian ini.

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HUBUNGAN KOMPLIKASI INTRA HEMODIALISIS DENGAN KUALITAS HIDUP PADA PASIEN CHRONIC KIDNEY DISEASE (CKD) STAGE V YANG MENJALANI HEMODIALISIS DI RUANG HEMODIALISA BRSU TABANAN TAHUN 2017

Jurnal Riset Kesehatan Nasional ◽

10.37294/jrkn.v2i1.95 ◽

2018 ◽

Vol 2 (1) ◽

pp. 9

Author(s):

Kadek G Pebriantari ◽

IGA Puja Astuti Dewi

Keyword(s):

Quality Of Life ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Significant Relationship ◽

Chi Square ◽

Cross Sectional ◽

Probability Sampling ◽

Ckd Stage ◽

Non Parametric

ABSTRAKLatar Belakang. Hemodialisis aman dan bermanfaat untuk pasien, namun bukan berarti tanpa efek samping. Berbagai komplikasi dapat terjadi pada saat pasien menjalani hemodialisis. Komplikasi ini dapat mengakibatkan timbulnya masalah baru yang lebih kompleks, yaitu dapat mempengaruhi kualitas hidup bahkan menimbulkan kematianTujuan. Untuk mengetahui hubungan komplikasi intra hemodialisis dengan kualitas hidup pada pasien Chronic Kidney Disease (CKD) Stage V yang menjalani hemodialisis.Metode. Jenis penelitian adalah analitik korelasional dengan pendekatan cross-sectional. Sampel pada penelitian ini berjumlah 166 responden diambil dengan teknik non probability sampling yaitu total sampling. Pengumpulan data menggunakan kuesioner dan lembar observasi,dianalisa dengan uji non parametric (Chi Square).Hasil. Rata – rata jumlah komplikasi intra hemodialisis adalah kurang dari dua komplikasi (sedikit komplikasi). Hipertensi intra hemodialisis adalah komplikasi terbanyak yang ditemukan (52,3%). Kejang dan penurunan kesadaran merupakan komplikasi yang tidak pernah dialami oleh responden selama penelitian (0%).Kualitas hidup pasien CKD stage V yang menjalani HD di BRSU Tabanan masuk dalam kategori kualitas baik. Hasil uji statistik diperoleh nilai p < 0.001 bahwa ada hubungan yang signifikan antara komplikasi intra hemodialisis dengan kualitas hidup pada pasien yang menjalani HD. Dari hasil analisis diperoleh pula nilai OR = 0,005, artinya responden yang memiliki banyak komplikasi mempunyai peluang 0,005 kali memiliki kualitas hidup buruk dibanding responden yang memiliki sedikit komplikasi.Kesimpulan. Ada hubungan yang signifikan antara komplikasi intra hemodialisis dengan kualitas hidup pada pasien yang menjalani hemodialisis.KataKunci: Komplikasi Intra Hemodialisis, Kualitas Hidup, Hemodialisis ABSTRACTBackground: Hemodialysis is safe and beneficial to the patient. However, there are various complications may occur when the patients undergo hemodialysis. These complications can lead to the emergence of new problems which are more complex and affect to the quality of life and even cause death.Aim: To determine the relationship of intra hemodialysis complications with quality of life in patients with Chronic Stage Kidney Disease (CKD) Stage V who undergo hemodialysis.Method:This study employed correlational analytic design with cross-sectional approach. To conduct this study, there were 166 respondents recruited as the sample by using probability sampling with total sampling technique. The data were collected by using questionnaire and observation sheet. Further, the data were analyzed by non-parametric test (Chi Square).Finding: The findings indicated that the average number of intra hemodialysis complications is less than two complications (few complications). There were found that 52.3% patients who had complication of hypertension intra hemodialysis. On the other hand, there was 0%of the respondents experienced seizures and decreased awareness complications during the study. The quality of life of CKD stage V patients underwenthemodialysis at BRSU Tabanan is categorized as good quality. The statistical test obtained p <0.001, it meant that there was a significant relationship between intra hemodialysis complications with quality of life in patients underwenthemodialysis. It also found that the analysis results of OR = 0.005, it meant that respondents who had many complications have a chance of 0.005 times experienced poor quality of life rather than the patients who had few complications.Conclusion: There is a significant relationship between intra hemodialysis complications and quality of life in patients undergo hemodialysis. Keywords: Complications of Intra Hemodialysis, Quality of Life, Hemodialysis

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Description of Serum Urea and Creatinine Levels Pre Hemodialysis and Post Hemodialysis at Royal Prima Hospital in Chronic Kidney Disease

Archives of The Medicine and Case Reports ◽

10.37275/amcr.v2i2.19 ◽

2021 ◽

Vol 2 (2) ◽

pp. 118-123

Author(s):

Raymond Nazimuddin Putra ◽

Valentine Athania Br Perangin-angin ◽

Sahna Ferdinand ◽

Erny Tandanu

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Serum Level ◽

Creatinine Level ◽

Kidney Function ◽

Kidney Failure ◽

Chronic Kidney Failure ◽

Serum Urea ◽

Urea Level ◽

Gradual Loss

Chronic Kidney Failure describes as the gradual loss of kidney functionand it is irreversible, to replace the loss of kidney function a therapy tokidney function is needed, which is hemodialysis. The objective of thisresearch is to know the levels of ureu and creatinine serum for prehemodialysis and post hemodialysis at RSU Royal Prima Medan. Themethods that are being used for this research is descriptive with 54 patientsas samples. The results of this research is loss of urea and creatinine serumlevel, with the average of urea level for pre hemodialysis is 128.11 mg/dL,and the average of urea level for post hemodialysis is 43.26 mg/dL with1,8% patient with low urea level, 50% with normal urea level, and 48.2%with high urea level. The average of creatine level for pre hemodialysis is11.56 mg/dL, and the average of creatine levels is 4.3 mg/dL, with all of thepatient still have a high creatinine levels. The conclusion is there is drop forboth urea and creatinen serum level, but the urea level for half of the patientdid not go down to normal, and for the creatinine level there is none of thepatient creatinine level that go down to normal.

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EFEKTIFITAS MENGUNYAH PERMEN KARET TERHADAP XEROSTOMIA PADA PASIEN CHRONIC KIDNEY DISEASE YANG MENJALANI HEMODIALISA DI RUMAH SAKIT AWAL BROS BATAM TAHUN 2019

Ners Journal ◽

10.52999/nersjournal.v1i2.68 ◽

2021 ◽

Vol 1 (2) ◽

Author(s):

PUTRI

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Kidney Failure ◽

Chronic Kidney Failure ◽

World Health ◽

Uncontrolled Hypertension ◽

Chewing Gum ◽

Electrolyte Balance ◽

Waste Products ◽

Number Of Patients

Chronic kidney failure or chronic kidney disease is a progressive deviation, kidney function that can not recover, where the body's ability to maintain metabolic balance, fluid and electrolytes, resulting in uremia. This condition is caused by chronic glomerulonephritis, pyelonephritis, uncontrolled hypertension, hereditary lesions, vascular abnormalities, urinary tract obstruction, diabetes, and infections. Today, chronic kidney disease is a disease whose prevalence continues to increase. World Health Organization (WHO) released data on growth in the number of patients with chronic kidney failure in 2013 increased by 50% from the previous year and in America the incidence of chronic kidney failure increased by 50% in 2014 and every year 200,000 Americans undergo hemodialysis Hemodialysis is one way to remove metabolic waste products in the form of a solution and water that is in the blood through a semipermeable membrane or called a dialyzer. The working principle of fluid transfer in hemodialysis is diffusion, osmosis, ultrafiltration and convection. Changes in fluid and electrolyte balance in Chronic Kidney Failure patients result in changes in salivary composition and flow (Fan, Zhang, Luo, Niu & Gu, 2013). In addition to changes in salivary composition and flow, patients with chronic renal failure also experience changes in dry mouth (xerostomia) due to increased ureum concentrations in the blood (Fan et al., 2013). Chewing Gum Xylitol is a candy that no artificial sweeteners activity of chewing gum, low-sugar two eggs approximately 10 minutes to 3x / day for 2 weeks would lead to mechanical stimulation and chemical that can move reflex saliva to stimulate the receptor that is monitored by the trigeminal nerve (V) and facial nerve (VII) as a taste. Sympathetic nerve stimulation will accelerate the secretion of all salivary glands in large quantities which can reduce the sensation of thirst that appears . From the results of research using the method of comparison in get , look the frequency of xerostomia before the intervention mostly dominated by xerostomia weight of 67% and the visible frequency of xerostomia after intervention largely dominated by xerostomia mild 67% , Based on the output "Test Statistics" in table 4.4 above, known p-value is 0,000. Because the value of 0.003 is smaller than <0.05, it can be concluded that "H0 is rejected", or in other words there is "Effectiveness of Chewing Gum Against Xerostomia in Chronic Kidney Disease Patients Who Underwent Hemodialysis at Batam Bros Initial Hospital in 2020

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P1835PREDICTION OF CHRONIC OF KIDNEY FAILURE BASED ON ARTIFICIAL INTELLIGENCE SYSTEM USING THE FUZZY DECISION TREE ALGORITHM

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfaa142.p1835 ◽

2020 ◽

Vol 35 (Supplement_3) ◽

Author(s):

Rifaldy Fajar ◽

Prihantini Jupri

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Decision Tree ◽

Kidney Failure ◽

Laboratory Tests ◽

Chronic Kidney Failure ◽

Decision Tree Algorithm ◽

Fuzzy Decision ◽

Fuzzy Decision Tree ◽

Tree Algorithm

Abstract Background and Aims Chronic kidney disease is one type of disease that can cause death. Until now, chronic kidney failure has no antidote, so this disease cannot be cured but can be slowed down or stopped its development. Early diagnosis of this disease will help to prevent these fatal consequences. To diagnose this disease, several laboratory tests are needed in which the results of these tests will be calculated and concluded the results by a doctor or medical practitioner. The development of science and technology, especially in the field of computers will help the work of doctors to analyze the results of laboratory tests become easier and faster. In this study, a prediction attempt is made using the Fuzzy Decision Tree classification algorithm, which is expected to obtain high accuracy results. Method This study uses the Chronic Kidney Disease (CKD) dataset taken from the UCI Machine Learning Repository. Data was collected from the hospital for approximately two months. This dataset covers a total of 400 samples with numerical attributes totaling 11 columns and nominal totaling 14 columns. Data samples were provided as many as 400 rows with 250 samples being the ckd group (positive for chronic kidney failure) and 150 samples for the notckd group (chronic kidney failure). But after going through the preprocessing stage, data that can be used amounted to 158 rows with 43 samples are the ckd group (positive chronic kidney failure) and 115 samples of the notckd group (negative chronic kidney failure). Results The trial was conducted using several predetermined thresholds and the most optimal accuracy was 98.3%, which showed a fairly high degree of accuracy. Conclusion Thus, it can be concluded that the Fuzzy Decision Tree algorithm can be said to be able to predict chronic kidney failure with a very good results.

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Influence of acute and chronic kidney failure in rats on the disposition and pharmacokinetics of ZYAN1, a novel prolyl hydroxylase inhibitor, for the treatment of chronic kidney disease-induced anemia

Xenobiotica ◽

10.1080/00498254.2016.1278287 ◽

2017 ◽

Vol 48 (1) ◽

pp. 37-44 ◽

Cited By ~ 4

Author(s):

Harilal Patel ◽

Amit Arvind Joharapurkar ◽

Vrajesh Bhaskarbhai Pandya ◽

Vishal Jagjivanbhai Patel ◽

Samadhan Govind Kshirsagar ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Kidney Failure ◽

Chronic Kidney Failure ◽

Prolyl Hydroxylase ◽

Prolyl Hydroxylase Inhibitor

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HUBUNGAN ANEMIA DENGAN KUALITAS HIDUP PADA PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISIS DIBAWAH 6 BULAN DI RUMAH SAKIT KHUSUS GINJAL RASYIDA MEDAN

Malahayati Nursing Journal ◽

10.33024/manuju.v2i3.2925 ◽

2020 ◽

Vol 2 (3) ◽

pp. 641-648

Author(s):

Muhammad Thob Dhiya’ul Haq ◽

Flora Marbun ◽

Aziva Zahrianis ◽

Maria Ulfa ◽

Novita K. Rambe ◽

...

Keyword(s):

Quality Of Life ◽

Kidney Failure ◽

Chronic Kidney Failure ◽

P Value ◽

Life Questionnaire ◽

Chi Square ◽

Cross Sectional ◽

Purposive Sampling ◽

The Impact

ABSTRACT : Background : Hemodialysis is a process in which blood is separated from harmful substances or poisons and excess fluid is then discharged through a dialysis device. Quality of life is a quality that is felt in everyday life one of which is the physical dimension, namely the impact of anemia experienced by patients. Purpose : to identify the relationship between anemia and quality of life in patients with chronic kidney failure who underwent hemodialysis for less than 6 months. Method: quantitative research design with analytic survey through a cross sectional approach. The population in this study were all patients with chronic kidney failure who did hemodialysis at the Rasyida Kidney Hospital in Medan. “The sample in this study amounted to 40 respondents with purposive sampling. Researchers requested laboratory results for the patient's hemoglobin level in the patient's medical record, and then the patient filled out a WHOQOL quality of life questionnaire”. Results: Patients with chronic kidney failure who underwent hemodialysis <6 months, the majority were male 26 people (65.0%), aged> 50 years (50.0%), married 38 people (95.0%), high school education was 17 people (42.5%), and had 14 self-employed jobs (35.0%). The majority experienced not anemia as many as 16 people (40,0%) and the majority experienced poor quality of life as many as 22 people (55,0%). Conclusion : Chi Square bivariate test results there is “a relationship between anemia and quality of life in patients with chronic kidney failure who undergo hemodialysis less than 6 months with a p-value of 0.002”. Keywords: Anemia, Quality Of Life, Chronic Kidney Disease, Hemodialysis INTISARI : HUBUNGAN ANEMIA DENGAN KUALITAS HIDUP PADA PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISIS DIBAWAH 6 BULAN DI RUMAH SAKIT KHUSUS GINJAL RASYIDA MEDAN Pendahuluan : Hemodialisis merupakan proses dimana darah dipisahkan dari zat atau racun berbahaya dan cairan berlebih kemudian dibuang melalui alat dialysis. Kualitas hidup merupakan kualitas “yang dirasakan dalam kehidupan sehari-hari salah satunya adalah dimensi fisik, yaitu dampak anemia yang dialami pasien”.Tujuan : Penelitian untuk mengidentifikasi hubungan antara anemia dan kualitas hidup pada pasien yang gagal ginjal kronik yang menjalani hemodialisa kurang dari 6 bulan.Metode : Penelitian ini menggunakan kuantitatif dengan survey analitik yang melalui pendekatan cross sectional. Populasi dalam penelitian ini yakni seluruh pasien gagal ginjal kronik yang melakukan hemodialisis di Rumah Sakit Khusus Ginjal Rasyida Medan “Sampel dalam penelitian ini berjumlah 40 responden dengan purposive sampling”. Peneliti meminta hasil laboratorium kadar hemoglobin pasien pada rekam medis pasien, dan kemudian pasien mengisi kuisioner kualitas hidup WHOQOL. Hasil : Pasien gagal ginjal kronik yang menjalani hemodialisa < 6 bulan mayoritas berjenis kelamin laki-laki 26 orang (65,0%), berusia >50 Tahun (50,0%), berstatus sudah menikah 38 orang (95,0%), pendidikan terakhir SMA 17 orang (42,5 %), dan memiliki pekerjaan wiraswasta 14 orang (35,0%). Mayoritas tidak mengalami anemia 16 orang (40,0%), anemia ringan 13 orang (32,5%), anemia sedang 11 orang (27,5%) dan mayoritas mengalami kualitas hidup buruk sebanyak 22 orang (55,0%). Hasil uji bivariate Chi Square terdapat “hubungan antara anemia dan kualitas hidup pada pasien gagal ginjal kronik yang menjalani hemodialisa kurang dari 6 bulan dengan nilai p-value 0,002”. Kata Kunci : Anemia, Kualitas Hidup, Gagal Ginjal Kronik, Hemodialisa

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ANALISIS PERBEDAAN BIAYA RIIL DENGAN TARIF INA-CBG’s DAN FAKTOR YANG MEMPENGARUHINYA UNTUK CHRONIC KIDNEY DISEASE PADA ERA JAMINAN KESEHATAN NASIONAL

Indonesian Journal of Medical and Pharmaceutical Science ◽

10.30659/ijmps.v1i1.2 ◽

2021 ◽

Vol 1 (1) ◽

pp. 6-12

Author(s):

Indriyati Hadi Sulistyaningrum ◽

Arifin Santoso ◽

Binarti

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Social Security ◽

Health Sector ◽

P Value ◽

Chi Square ◽

Cross Sectional ◽

The Real ◽

Real Cost ◽

Real Costs

Background: The National Social Security System (SJSN) is a system in the health sector that aims to provide comprehensive social security in order to create a just, prosperous and prosperous society. According to WHO growth in the number of Chronic Kidney Disease in 2013 increased by 50% from 2012 even in Southeast Asia to the number of sufferers of Chronic Kidney Disease> 380 million people. While in Indonesia, it has increased by 10% every year. This study aims to determine the differences between INA-CBG rates and the real costs of JKN-era Chronic Kidney Disease patients in RSISA Semarang. Method: This research is an observational study with a retrospective analytic descriptive design with quantitative data. The method used is the Cross Sectional method that makes observations, and can describe the factors that influence the real cost of hospitals. The population was 589 patients with Chronic Kidney Disease and 238 patients and analyzed using the chi-square statistical test with p-value <0.05. Results: The results of the study that as many as 14 patients (5.9%) aged 18-28 years, as many as 50 patients (21.0%) aged 29-39 years, as many as 82 patients (34.5%) aged 40-50 years , as many as 68 patients (28.6%) aged 51-60 years, as many as 21 patients (8.8%) aged 61-70 years as many as 3 patients (1.3%) aged 71-80 years. The research results obtained a p-value of 0,000. Conclusion: There is a Difference between Hospital Real Costs and INA-CBG's Rates for Chronic Kidney Disease in JKN Era in Semarang Hospital in 2018. There are no factors that affect the real costs in chronic kidney disease patients JKN participants in 2018 both class of care, length of treatment (LOS), and disease severity.

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Prevalence of Mineral Bone Disease in Chronic Kidney Disease Patients using Biochemical Markers

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2020/44759.13902 ◽

2020 ◽

Author(s):

Reeta Choudhary ◽

Charu Yadav ◽

Pallavi Jain ◽

Shyam Bihari Bansal ◽

Beena Bansal ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Renal Function ◽

Kidney Disease ◽

Bone Disease ◽

Biochemical Markers ◽

Treatment Protocol ◽

Health Concern ◽

P Value ◽

Bone Homeostasis ◽

Chi Square

Introduction: Chronic Kidney Disease (CKD), a condition characterised by a gradual loss of renal function over the time, has emerged as a major public health concern with 17% prevalence in Indian population. Decrease in renal function in CKD leads to progressive metabolic derangements of mineral and bone homeostasis which in turn makes them susceptible to bone related and cardiovascular complications. Aim: To calculate the prevalence of Mineral Bone Disease (MBD) in CKD patients by estimation of biochemical markers Calcium (Ca), Phosphorus (P), Alkaline Phosphatase (ALP) and intact Parathyroid Hormone (iPTH) and to analyse their prevalence across different stages of CKD. Materials and Methods: This was a hospital based cross-sectional study conducted at Medanta-the Medicity hospital in 2300 previously diagnosed CKD cases who visited the Nephrology OPD for their follow-up visits, from October 2017 to December 2018. Serum levels of Ca, P, ALP and iPTH were estimated in VITROS 4600 and ARCHITECT I system automated analysers using commercially available kits. Stage-wise and overall prevalence of deranged levels of these markers was calculated and based on this the prevalence of MBD was calculated. Statistical analysis was done using SPSS version 24.0. Descriptive analysis of quantitative parameters was expressed as means and standard deviation. The analysis for comparison among three or more categories was done using one-way ANOVA. Categorical data was analysed using Chi square test for proportions and data was expressed as absolute number and percentage in a contingency table along with the chi square and p-values. The p-value <0.05 was considered statistically significant. Results: Prevalence of MBD in overall CKD patients was 81.6%; the stage-wise prevalence being 63.4% (stage 3), 76.9% (stage 4), 87.6% (stage 5) and 91.3% (stage 5D). The overall prevalence of hypocalcaemia, hyperphosphatemia, high ALP and secondary hyperparathyroidism was 27.8%, 48.3%, 26.5% and 75.6%, respectively. Conclusion: The present study reports an alarmingly high prevalence of MBD in CKD cases; the disease burden being maximum in stage 5 and 5D. This was despite the administration of relevant medications and supplements to prevent MBD. Thus, there needs to be some change in treatment protocol to reduce the prevalence of MBD to improve the quality of life and reduce mortality rate in CKD patients.

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Correlation Of Hemoglobin And Blood Creatinine Levels In Chronic Kidney Disease Patients Post Repeated Transfusion

Jaringan Laboratorium Medis ◽

10.31983/jlm.v2i2.7030 ◽

2021 ◽

Vol 2 (2) ◽

pp. 51-55

Author(s):

Eko Naning Sofyanita ◽

Roni Afriansya ◽

Nur Indah Palupi

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Serum Creatinine ◽

Significant Relationship ◽

Blood Cells ◽

The Body ◽

Chi Square ◽

Chi Square Test ◽

The Relationship ◽

Blood Creatinine

Kidneys are part of the body that has an important role. One of the functions of the kidney is the production of erythropoietin. Erythropoietin stimulates the production of red blood cells. People or patients who have kidney problems can cause anemia. This study aims to determine the relationship between hemoglobin levels and blood creatinine levels in patients with chronic kidney disease after receiving a transfusion. Blood creatinine levels in this study were used as an index to measure kidney function. The study was conducted at the Wira Tamtama Hospital Semarang by taking data on 20 patients in 2020 with chronic kidney disease and taking data on hemoglobin (cut-off 12 g/dL) and serum creatinine (cut-off 1.5 mg/dL). The relationship between the two was calculated by chi-square test and found 80% of patients with low hemoglobin in patients with high creatinine levels and 0% of patients with low hemoglobin in patients with normal creatinine levels (p=0.040). There is a risk of decreased hemoglobin levels (OR = 3,442) in patients with high creatinine levels. It was concluded that there was a significant relationship between hemoglobin levels and blood creatinine levels and patients with high creatinine levels tended to be at risk of anemia.

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Pattern of Herbal and Dietary Supplement Usage and Conventional Medication Adherence among Patients with Chronic Kidney Disease: A Survey Finding

IIUM Medical Journal Malaysia ◽

10.31436/imjm.v18i3.205 ◽

2020 ◽

Vol 18 (3) ◽

Author(s):

Sowtali SN ◽

Mohd Rasani AA ◽

Mohd. Shah AS ◽

Mohd. Yusoff D ◽

Draman CR ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Medication Adherence ◽

Kidney Disease ◽

Dietary Supplements ◽

P Value ◽

Chi Square ◽

Exact Test ◽

Conventional Medication ◽

Chi Square Test ◽

Demographic Background

Introduction: There is widespread use of herbal and dietary supplements worldwide among patients despite robust clinical evidence of its efficacy. This may lead to adverse effects, such as diabetes, hypertension, stroke, cardiovascular risk and kidney problems due to inappropriate self-prescription. This study was performed to determine the prevalence of herbal and dietary supplements usage among patients with chronic kidney disease and its association with the socio-demographic background and the conventional medication adherence. Materials and methods: A survey was conducted among 78 chronic kidney disease patients attending the Nephrology Clinic, Hospital Tengku Ampuan Afzan, Kuantan, Pahang. Data were collected using a questionnaire and analyzed using descriptive statistics, Chi Square Test and Fisher’s Exact Test. The p-value was set to be less 0.05 for its level of significance. Results: Most of the patients aged more than 50 years (89.7%), female (53.8%), unemployed (41%) and from lower socioeconomic earners (75.6%). Only 5.2% of respondents reported using herbal and dietary supplements. There was no association between socio-demographic background with the herbal and dietary supplements usage. Similarly, there was no association between herbal and dietary supplements usage and the conventional medication adherence. Conclusion: This study provides a good baseline on the usage of herbal and dietary supplements use among chronic disease patients. It can be concluded that the level of awareness among the patients is good. Nevertheless, a larger study shall be performed in the future to explore the pattern of association.

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