scholarly journals Drug prices in Latin American countries: the case of rheumatoid arthritis Biosimilars

2021 ◽  
Vol 61 (1) ◽  
Author(s):  
Gabriela Bittencourt Gonzalez Mosegui ◽  
Fernando Antõnanzas ◽  
Cid Manso de Mello Vianna ◽  
Paula Rojas
Keyword(s):  
Rheumatoid Arthritis ◽  
United States ◽  
Latin American ◽  
United States Of America ◽  
Purchasing Power Parity ◽  
The United States ◽  
Power Parity ◽  
Drug Prices ◽  
The Us ◽  
Latin American Countries

Abstract Background The objective of this paper is to analyze the prices of biological drugs in the treatment of Rheumatoid Arthritis (RA) in three Latin American countries (Brazil, Colombia and Mexico), as well as in Spain and the United States of America (US), from the point of market entry of biosimilars. Methods We analyzed products authorized for commercialization in the last 20 years, in Brazil, Colombia, and Mexico, comparing them to the United States of America (USA) and Spain. For this analysis, we sought the prices and registries of drugs marketed between 1999 and October 1, 2019, in the regulatory agencies’ databases. The pricing between countries was based on purchasing power parity (PPP). Results The US authorized the commercialization of 13 distinct biologicals and four biosimilars in the period. Spain and Brazil marketed 14 biopharmaceuticals for RA, ten original, four biosimilars. Colombia and Mexico have authorized three biosimilars in addition to the ten biological ones. For biological drug prices, the US is the most expensive country. Spain’s price behavior seems intermediate when compared to the three LA countries. Brazil has the highest LA prices, followed by Mexico and Colombia, which has the lowest prices. Spain has the lowest values in PPP, compared to LA countries, while the US has the highest prices. Conclusion The economic effort that LA countries make to access these medicines is much higher than the US and Spain. The use of the PPP ensured a better understanding of the actual access to these inputs in the countries analyzed.

scholarly journals Availability of biological cancer drugs under research: registration and price in Brazil, Colombia, and Mexico

2020 ◽  
Vol 30 (4) ◽  
Author(s):  
Gabriela Bittencourt Gonzalez Mosegui ◽  
Fernando Antõnanzas Villar
Keyword(s):  
Latin American ◽  
Purchasing Power Parity ◽  
The United States ◽  
Cancer Drug ◽  
Regulatory Agencies ◽  
Purchasing Power ◽  
Power Parity ◽  
Drug Access ◽  
The Usa ◽  
Latin American Countries

Abstract This study seeks to understand biological cancer drug availability through registration and prices of the biological agents used for cancer therapy and authorized for sale in the last 5 years in Brazil, Colombia, and Mexico, comparing the data to those for the United States of America (USA) and Spain. The regulatory agencies’ websites were assessed for drugs registered between January 1, 2014, and February 20, 2019. Drug prices were sought in the clerical databases. Prices were also compared using purchasing power parity (PPP). The comparison between the purchasing power (PP) of the three Latin American countries is hampered by market heterogeneity and uncertainty in the data. There is no registration synchronization. The average difference between the launch time in the USA and in the other countries is 1.6 to 2.6 years. The USA has the lowest PPP values, compared to the Latin American countries studied, but higher prices. Differences in registration time reveal issues in drug access in the Latin American countries studied or a lack of equity between countries. The economic effort that these countries make to have access to these supplies is much higher than that of the USA and Spain.

LATIN AMERICAN POLICY COMPONENT OF THE US, PRC AND RUSSIAN FEDERATION: POLICY OF THE UNITED STATES OF AMERICA

2021 ◽  
Vol 1 (5) ◽  
pp. 154-177
Author(s):  
D. V. GORDIENKO ◽  
Keyword(s):  
United States ◽  
National Security ◽  
Latin American ◽  
United States Of America ◽  
Political Leadership ◽  
The United States ◽  
The Us ◽  
The World ◽  
The Military ◽  
The Impact

The paper considers the assessment of the influence of the Latin American component of the policy of the states of the strategic triangle "Russia-China-USA" on the national security of these countries. An approach to comparing the impact of the component is proposed, which makes it possible to identify the priorities of Russia's policy in Latin America and other regions of the world. The results of the work can be used to justify recommendations to the military-political leadership of our country.

Overstretching or Overreaction? China’s Rise in Latin America and the US Response

2021 ◽  
pp. 186810262110282
Author(s):  
Xiaoyu Pu ◽  
Margaret Myers
Keyword(s):  
United States ◽  
Latin America ◽  
Latin American ◽  
The United States ◽  
China’S Rise ◽  
The Us ◽  
China's Rise ◽  
Latin American Countries ◽  
Latin American And Caribbean

This article examines how the Chinese elites are interpreting China’s growing presence in the Latin American and Caribbean (LAC) region and the various ways in which the United States is responding to China’s expanding activity in the region. Some of China’s elites caution that China’s international posturing could be overly assertive. Regarding China’s growing role in the LAC, they have made a note of US sensitivities, in addition to China’s challenges and limitations in various Latin American countries. Regarding the US response, some US concerns may be legitimate, and others are less valid. Looking ahead, even though US–China interactions in the LAC will remain competitive, the US and China could potentially avoid counterproductive policies while also pursuing pragmatic co-operation. While China does not yet face a serious problem of strategic overstretching in the LAC, China’s domestic debate on the topic will provide feedback to China’s policymakers and promote fruitful China–LAC relations.

From the “Pink Tide” to “Soft Coup d’État” in Latin America: the Case of Bolivia

2021 ◽  
Vol 19 (5-6) ◽  
pp. 597-625
Author(s):  
Martha I. Chew Sánchez
Keyword(s):  
United States ◽  
Latin America ◽  
Latin American ◽  
The United States ◽  
Coup D'etat ◽  
Economic Relationships ◽  
The Us ◽  
The Impact ◽  
Latin American Countries

Abstract This article addresses the impact of settler colonialism by the Spanish and United States in the American continent in forming the base, development, and power of capitalism in the West. It provides a general overview of the United States’ unequal economic relationships with Latin American countries since the end of the nineteenth century to the present. It highlights the role evangelist groups have in changing the way coup d’états have been taking place in the region, in particular, to countries that had democratically elected presidents who were part of the “Pink Tide” and had a program to counterbalance neoliberal policies that were contributing to unprecedented economic inequality in their societies. One of the central questions in this work is the role of coloniality within Latin American countries and between the US and Latin America in the coup d’état against Evo Morales in Bolivia on November 10, 2019.

scholarly journals The Political and Economic Dimensions of China’s Relations with Latin America ( الابعاد السياسية والاقتصادية لعلاقات الصين مع امريكا اللاتينية )

2020 ◽  
Vol 11 (02) ◽  
pp. 20224-20229
Author(s):  
Prof. Nadia Dheyaa Shkara
Keyword(s):  
United States ◽  
Latin American ◽  
United States Of America ◽  
Raw Materials ◽  
The United States ◽  
The Philippines ◽  
Steady Growth ◽  
Scientific Analysis ◽  
The World ◽  
Latin American Countries

This research uses scientific analysis to look at China's relations with Latin American countries, especially its investment in those countries. There are two objectives behind Chinese investments in South America. The first is to solidify its position as the second largest economic power in the world after the United States of America. China's position is further ensured by its huge store of raw materials and energy sources that support its accelerating economic needs of energy to keep pace with the steady growth of its economy. The second objective is to prevent and deter the United States of America from harming the growing Chinese interests in the world by restricting the effects of the American Containment and Pivot strategies, which revealed the determination of the American administration to besiege China, and its growing influence, economically & politically by alliances & treaties, and to besiege China militarily by American bases Japan, South Korea, the Philippines and others of China's neighbors. Thus, China considered it only fair to retaliate by strengthening its relations with U.S.A. neighbors, especially the Latin American countries who are U.S.A.'s backyard and strategic backers, and who can restrict the American ability to harm China's vital interests.

scholarly journals The Need for Integrating the Back End of the Nuclear Fuel Cycle in the United States of America

MRS Advances ◽  
2018 ◽  
Vol 3 (19) ◽  
pp. 991-1003 ◽  
Author(s):  
Evaristo J. Bonano ◽  
Elena A. Kalinina ◽  
Peter N. Swift
Keyword(s):  
United States ◽  
Nuclear Fuel ◽  
United States Of America ◽  
Spent Nuclear Fuel ◽  
Fuel Cycle ◽  
Nuclear Fuel Cycle ◽  
The United States ◽  
Spent Fuel ◽  
Dry Storage ◽  
The Us

ABSTRACTCurrent practice for commercial spent nuclear fuel management in the United States of America (US) includes storage of spent fuel in both pools and dry storage cask systems at nuclear power plants. Most storage pools are filled to their operational capacity, and management of the approximately 2,200 metric tons of spent fuel newly discharged each year requires transferring older and cooler fuel from pools into dry storage. In the absence of a repository that can accept spent fuel for permanent disposal, projections indicate that the US will have approximately 134,000 metric tons of spent fuel in dry storage by mid-century when the last plants in the current reactor fleet are decommissioned. Current designs for storage systems rely on large dual-purpose (storage and transportation) canisters that are not optimized for disposal. Various options exist in the US for improving integration of management practices across the entire back end of the nuclear fuel cycle.

The Epidemiology of Drug Promotion

1977 ◽  
Vol 7 (2) ◽  
pp. 157-166 ◽  
Author(s):  
Milton Silverman
Keyword(s):  
United States ◽  
Latin America ◽  
Latin American ◽  
Prescription Drugs ◽  
The United States ◽  
Corporate Ethics ◽  
Social Responsibilities ◽  
The One ◽  
Global Company ◽  
Latin American Countries

A survey was conducted on the promotion of 28 prescription drugs in the form of 40 different products marketed in the United States and Latin America by 23 multinational pharmaceutical companies. Striking differences were found in the manner in which the identical drug, marketed by the identical company or its foreign affiliate, was described to physicians in the United States and to physicians in Latin America. In the United States, the listed indications were usually few in number, while the contraindications, warnings, and potential adverse reactions were given in extensive detail. In Latin America, the listed indications were far more numerous, while the hazards were usually minimized, glossed over, or totally ignored. The differences were not simply between the United States on the one hand and all the Latin American countries on the other. There were substantial differences within Latin America, with the same global company telling one story in Mexico, another in Central America, a third in Ecuador and Colombia, and yet another in Brazil. The companies have sought to defend these practices by contending that they are not breaking any Latin American laws. In some countries, however, such promotion is in clear violation of the law. The corporate ethics and social responsibilities concerned here call for examination and action.

Great Britain and the United States: Two nations divided by an attitude?

English Today ◽  
2018 ◽  
Vol 34 (4) ◽  
pp. 21-28
Author(s):  
Carmen Ebner
Keyword(s):  
United States ◽  
Great Britain ◽  
United States Of America ◽  
The United States ◽  
British English ◽  
Doctoral Thesis ◽  
Linguistic Differences ◽  
The Us ◽  
Selection Of ◽  
Similar Search

Having studied attitudes towards usage problems such as the notorious split infinitive or the ubiquitous literally in British English as part of my doctoral thesis, I was intrigued by the sheer lack of scientific studies investigating such attitudes. What was even more intriguing was to discover that the same field and the same usage problems seem to have received a different treatment in the United States of America. While my search for previously conducted usage attitude studies in Great Britain has largely remained fruitless, besides two notable exceptions which I will discuss in detail below (see Section 3), a similar search for American usage attitude studies resulted in a different picture. Considerably more such studies seem to have been conducted in the US than in Great Britain. On top of cultural and linguistic differences between these two nations, it seems as if they also hold different attitudes towards studying attitudes towards usage problems. Now the following question arises: why do we find such contradictory scientific traditions in these two countries? In this paper, I will provide an overview of a selection of American and British usage attitude studies. Taking into account differences between the American and British studies with regard to the number of usage problems studied, the populations surveyed and the methods applied, I will attempt to capture manifestations of two seemingly diverging attitudes towards the study of usage problems. By doing so, I will provide a possible explanation for the lack of attention being paid to usage attitudes in Great Britain.

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