Family Data Concerning the Hypothesis of Hereditary Predisposition Toward Alcoholism

1960 ◽  
Vol 106 (444) ◽  
pp. 1068-1072 ◽  
Author(s):  
Ian Gregory

There is evidence of unduly high frequencies of alcoholism, psychopathy and criminality among the relatives of alcoholics. Åmark (1951) found a frequency of alcoholism among the brothers and fathers of 645 Swedish alcoholics to be about 25 per cent. (Fremming's estimate of alcoholism among 1,730 males from the Danish population being 3·4 per cent.). In a more recent study of family data on 1,000 patients admitted to a Canadian mental hospital that included 56 patients with alcoholism, the present author (Gregory, 1959) found a recorded history of excessive drinking among 23·2 per cent. of the fathers of the alcoholics, among 1·8 per cent. of the mothers, and among 4·2 per cent. of their siblings. Allowing for the age and sex of these siblings, it would appear that there was a lifetime expectancy of excessive drinking of at least 14 per cent. among the brothers of these alcoholic patients. These figures compare with a minimal estimated lifetime expectancy of alcoholism amounting to 1·6 per cent. of the total population, or at least 2·7 per cent of the corresponding male population of Ontario.

1992 ◽  
Vol 26 (2) ◽  
pp. 342-352 ◽  
Author(s):  
Darina Vasileva

The history of the emigration of Bulgarian Muslim Turks to Turkey is more than a century old. The violation of the human rights of ethnic Turks by the totalitarian regime during the 1980s resulted in the most massive and unpredictable migration wave ever seen in that history. This article examines the complexity of factors and motivations of the 1989 emigration which included almost half of the ethnic Turks living in Bulgaria and constituting until that time 9 percent of the total population. The author considers the strong and long-lasting effect of this emigration—followed by the subsequent return of half of the emigrants after the fall of the regime—both on Bulgaria's economy and on the political life of the society. The article aims also at providing a better understanding of the character of ethnic conflicts in posttotalitarian Eastern Europe.


2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Anand N. Shukla ◽  
Tarun Madan ◽  
Bhavesh M. Thakkar ◽  
Meena M. Parmar ◽  
Komal H. Shah

This epidemiological study was designed to evaluate the prevalence of undetected hypertension in an apparently healthy western Indian population having no history of major illness. 3629 individuals of ≥18 years of age were included in the study. Hypertension (HTN) was defined as systolic blood pressure (SBP) ≥ 140 mmHg or diastolic blood pressure (DBP) ≥ 90 mmHg and prehypertension (PHTN) as SBP ≥ 120–139 mmHg or DBP ≥ 80–89 mmHg, but without HTN. The prevalence of undiagnosed HTN in the total population was 26% and was 11% and 40% in the young (≤40-year) and old (>40-year) populations, respectively. The prevalence of PHTN, 40% in the overall population, was nearly the same in the young (39%) and the old population (42%). The risk factor most strongly associated with PHTN and HTN was obesity, showing the highest odds ratio in the overall (PHTN 2.14; 95% CI 1.20–3.81; HTN 2.72; 95% CI 1.53–4.85), the young (PHTN 2.29; 95% CI 1.25–4.21; HTN 2.92; 95% CI 1.59–5.35), and the old (PHTN 1.13; 95% CI 0.65–1.96; HTN 1.38; 95% CI 0.79–2.4) populations. Hypertension is a major risk factor for cardiovascular diseases which must not be ignored, especially in the western Indian population.


Cephalalgia ◽  
2001 ◽  
Vol 21 (7) ◽  
pp. 748-752 ◽  
Author(s):  
P Tfelt-Hansen

Headache research in Denmark started with the description in 1949 by Dalsgaard-Nielsen of the percutaneous nitroglycerin test. In 1976 Jes Olesen started The Copenhagen Acute Headache Clinic and from that time modern headache research began in Denmark. Specific changes in regional cerebral blood flow during attacks of migraine with aura, spreading oligaemia, were described for the first time in 1980. The first headache classification with operational diagnostic criteria was published in 1988 and used in a Danish population study from 1989. The lifetime prevalence of migraine was 8% in men and 25% in women. An intravenous nitroglycerin test was introduced in 1989 and has been developed as an experimental headache model. In 1993 it was suggested by Jes Olesen et al. that NO supersensitivity could be a possible molecular mechanism of migraine pain. Recent genetic studies have supported the distinction between migraine with aura and migraine without aura. From the middle of the 1980s the pathophysiology of tension-type headache has been investigated and recent results indicate central sensitization in patients with chronic tension-type headache.


1993 ◽  
Vol 107 (3) ◽  
pp. 179-182 ◽  
Author(s):  
J. R. Cullen ◽  
M. J. Cinnamond

The relationship between diabetes and senbsorineural hearing loss has been disputed. This study compares 44 insulin-dependent diabetics with 38 age and sex matched controls. All had pure tone and speech audiometry performed, with any diabetics showing sensorineural deafness undergoing stapedial reflecx decat tests. In 14 diabetics stapedial reflex tests showed no tone decay in any patient, but seven showed evidence of recruitment. Analysis of vaiance showed the diabetics to be significantly deafer than the control population.The hearing loss affected high frequencies in both sexes, but also low frequencies in the male. Speech discrimination scores showed no differences. Further analysis by sex showed the males to account for most of the differences. Analysys of the audiograms showered mostly a high tone loss. Finally duration of disbetes, insulin dosage and family history of diabtes were not found to have a significant effect on threshold.


2021 ◽  
pp. 010-018
Author(s):  
Perrotta Giulio

Purpose: This research addresses the topic of anxiety, phobic and obsessive disorders. In this research, the theme is addressed to the psychopathological investigation of personalities, according to the PICI-2TA model (Perrotta Integrative Clinical Interviews, version 2-TA), the PAD-Q (Perrotta Affective Dependency Questionnaire), the PSM (Perrotta Sexual Matrix), the PDM-Q (Perrotta Defence Mechanisms Questionnaire) and the PHEM model (Perrotta Human Emotions Model), in order to design a direct and functional psychotherapeutic protocol to manage the psychopathological process in the shortest time possible, according to the principles of efficiency, effectiveness and economy, trying to reduce the symptomatology until the total regression by the fifth-tenth session. Methods: Clinical interview and administration of the PICI-2, the PAD-Q, the PSM, and the PDM-Q. Results: In the male group, aged 18-36 years, there were 8 people, of whom 6 (75%) reacted to the total resolution of the neurotic symptomatology described between the fifth and ninth sessions, while only 2 (25%) said they felt their neurotic symptoms had subsided. In the male group, aged 37-54 years, there are 5 people, of whom 4 (80%) reacted to the total resolution of neurotic symptomatology described between the fifth and ninth sessions. In the male group, aged 55-72 years, there were 6 people, of whom 4 (66.6%) reacted to the total resolution of neurotic symptoms described between the ninth and tenth sessions. In the female group, aged 18-36 years, there were 22 people, of whom 18 (82%) reacted to the total resolution of neurotic symptoms described between the fifth and ninth sessions. In the female group, aged 37-54 years, there were 13 people, of whom 9 (69.2%) reacted to the total resolution of neurotic symptoms described between the fifth and ninth session. In the female group, aged 55-72 years, there were 11 people, of whom 8 (72.7%) reacted to the total resolution of neurotic symptoms described between the fifth and ninth sessions. Conclusions: The research showed that the PPP-DNA protocol, for neurotic disorders, was effective in the total population sample for 74.36%, for the fractionated male population sample for 73.86% and for the fractionated female population sample for 74.86%, with resistance to change identified in adverse conditions of family, environmental, socio-cultural and temporal type (of duration of neurotic symptomatology), however able to promote an attenuation of the symptomatology suffered by at least 50%.


LingVaria ◽  
2017 ◽  
Vol 12 (23) ◽  
pp. 167-181
Author(s):  
Zbigniew Babik

This two-part paper presents the theoretical assumptions, and gives an account of the current progress of a Slavistic appendix which is being prepared by the present author for an as yet unwritten Dictionary of Polish topolexemes, an attempt to inventory and describe the entire lexical deposit of potentially Proto-Slavic origin contained in Polish place and terrain names. The aim of this research is to determine, based on the varying degree of its preservation in the toponymy of different regions, the place where Proto-Slavic vocabulary was formed. The first part presents the history of research together with a criticism of previous attempts, and explains the main methodological rules, focusing on the reconstruction of words which are not attested in Polish as appellatives. It also discusses the state of the source base, and problems which arise during work with various types of Polish toponomastic sources.


2017 ◽  
Vol 30 ◽  
pp. 301-324 ◽  
Author(s):  
J. W. Hanson ◽  
S. G. Ortman

The last few years have seen a growing interest in the urbanism of the Greek and Roman world. This has led to a consensus of sorts about some of its vital statistics, such as the sizes of the populations of the most important settlements and the size of the overall urban population, the urbanization rate (i.e., the share of individuals that lived in urban, rather than rural, contexts), and the total population. A good example comes from W. Scheidel in the Cambridge economic history of the Greco-Roman world. According to him, it is likely that c.1.5 million people lived in the 5 largest cities of the Greco-Roman world by the 2nd c. A.D. These included Rome, which is usually agreed to have had a population of about 1 million; Alexandria, which might have had c.500,000; Antioch, which could have had at least 150,000; and Carthage and Ephesus (Scheidel does not give explicit figures for those).


2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Carlos Chavez-Mendoza ◽  
LUIS IGNACIO MANZO-ARELLANO ◽  
AIRY SANTILLÁN-CERÓN ◽  
SAGRARIO CASTILLO-JUÁREZ ◽  
CÉSAR ULISES RAMÍREZ-SALGADO ◽  
...  

Abstract Background and Aims The use of intradialytic exercise has been associated with improved clearance, oxygen consumption, quality of life, and physical performance. The aim of this study was to describe the association between of intradialytic exercise and some outcomes in a Mexican maintenance hemodialysis (HD) population. Method Observational comparative study that included 84 maintenance HD patients from one HD center in Mexico City. The population was grouped according to the intradialytic exercise local record. The aerobic intradialytic exercise protocol includes cycling for 30-45 min during the first 2 hours of the HD according to each patient’s ability. A retrospective registry of clinical and biochemical parameters was realized. Also, the hemodynamic parameters of the last six HD sessions for each patient was included. Data analysis was carried out through descriptive and inferential statistics. Results Of the total population, 45.2% were men (n= 38) and the mean age was 53.6 + 17 years. Fifty one percent (n= 43) had diabetes mellitus (DM), which resulted more prevalent in the subgroup of patients without intradialytic exercise (p=0.03) No differences between groups were present in age, history of previous peritoneal dialysis or kidney transplant. The rest of baseline data are shown in Table 1. The subgroup of patients who underwent intradialytic exercise presented higher levels of serum albumin (p=0.03) and lower levels of parathormone (p=0.03). A total of 504 HD sessions were analysed and intradialytic exercise was performed in 64.3% (n=324). Patients in the intradialytic exercise program presented high levels of systolic and diastolic blood pressure (graphic 1). Intradialytic hypotension occurred in 5.2% (n=26) and no differences are shown between groups (p=0.78). No mayor side effects were reported. Conclusion The intradialytic exercise could improve nutritional and bone-mineral status markers. The patients in an intradialytic exercise program presented higher levels of blood pressure.


2020 ◽  
Vol 2020 ◽  
pp. 1-16
Author(s):  
Anna Tagka ◽  
George I. Lambrou ◽  
Electra Nicolaidou ◽  
Stamatios G. Gregoriou ◽  
Alexandra Katsarou-Katsari ◽  
...  

Contact dermatitis is a well-known skin condition, which is related to stimuli and environmental exposure to chemicals, affecting all ages as well as both genders. In the present work, we attempt to investigate the patterns of contact sensitization, with respect to the personal history of atopy (AT), in Greece in a large number of allergens, using patch testing. The retrospective analysis included clinical routine data of 1978 patients collected from 2014 to 2016 in the Laboratory of Patch Testing, National Referral Centre of Occupational Dermatoses. Sensitization, in all cases, was tested with 28 allergens of the European baseline series as adjusted to our local circumstances and clinical experience. A total population of 1978 patients was evaluated, with a male-to-female ratio of 0.45 (1359 females/619 males). From our patient cohort, 693 (35%) patients were evaluated with a history of atopy, while 1285 (65%) were nonatopic. The five most prevalent allergens in the total population without AT were nickel sulphate 5% (15.47%), fragrance mix (I) 8% (9.10%), balsam of Peru (6.47%), cobalt chloride 1% (4.70%), and thiomersal 0.1% (4.10%). Respectively, in the total population with AT, the five most prevalent allergens were nickel sulphate 5% (10.36%), fragrance mix (I) 8% (5.11%), balsam of Peru (3.29%), thiomersal 0.1% (3.03%), and cobalt chloride 1% (2.78%). Contact dermatitis surveillance is of great importance towards the clinical and systematic understanding of the disease. Further studies should be directed towards that end, in order to facilitate more effective health policies.


1970 ◽  
Vol 15 (2) ◽  
pp. 75-77
Author(s):  
M Alamgir Chowdhury ◽  
Mousumi Malakar ◽  
SM Golam Rabbani ◽  
Naseem Yasmeen ◽  
Shahidul Islam

Juvenile nasopharyngeal angiofibroma is a benign vascular neoplasm, but it is locally aggressive. This accounts for less than 0.5% of all the neoplasm in the head & neck region in the male population only. Here we report a case of 10-year-old boy with a blackish red smooth polypoidal mass in the nasal cavity, with history of recurrent epistaxis. On physical examination it was suspected as nasopharyngeal angiofibroma. We removed it totally by lateral rhinotomy approach. And the diagnosis was nasopharyngeal angiofibroma on histopathology. Key words: Angiofibroma; Nasopharyngeal. DOI: 10.3329/bjo.v15i2.5061 Bangladesh J Otorhinolaryngol 2009; 15(2): 75-77


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