Prolonged High Dosage Ataractic Medication in Chronic Schizophrenia

1964 ◽  
Vol 110 (464) ◽  
pp. 61-63 ◽  
Author(s):  
D. Rosati
Keyword(s):  
United States ◽  
Relapse Rate ◽  
Chronic Schizophrenia ◽  
The United States ◽  
Small Study ◽  
Double Blind ◽  
Mental Hospitals ◽  
Therapeutic Results ◽  
Near Future

Ataractic drugs have been the mainstay of treatment in schizophrenia for the last eight years. Since their introduction, mental hospitals, in various areas of the United States and in every country, have been able to discharge more patients than they admit. Despite this fact there remains much divergent opinion about the value of these drugs, doubt arising from inconsistent therapeutic results and the relapse rate. Also, some double-blind studies have cast some doubt upon the efficiency of these drugs. We are reporting this relatively small study because we feel that it opens an insight and possibly suggests a method of standardizing treatment in the near future.

scholarly journals ArcGIS Urban: an application for plan assessment

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Ellen Soward ◽  
Jianling Li
Keyword(s):  
United States ◽  
The United States ◽  
Spatial Context ◽  
Future Studies ◽  
Planning Profession ◽  
Gis Tools ◽  
Comprehensive Plans ◽  
Near Future ◽  
The City

AbstractMost cities in the United States rely on zoning to address important planning-related issues within their jurisdictions. Planners often use GIS tools to analyze these issues in a spatial context. ESRI’s ArcGIS Urban software seeks to provide the planning profession with a GIS-based solution for various challenges, including zoning’s impacts on the built environment and housing capacity.This research explores the use of ArcGIS Urban for assessing the existing zoning and comprehensive plans in meeting the projected residential growth in the near future using the City of Arlington, Texas as a case study. The exploration provides examples and lessons for how ArcGIS Urban might be used by planners to accomplish their tasks and highlights the capabilities and limitations of ArcGIS Urban in its current stand. The paper is concluded with some suggestions for future studies.

scholarly journals Impact of Fatty Acid Supplementation on Cognitive Performance among United States (US) Military Officers: The Ranger Resilience and Improved Performance on Phospholipid-Bound Omega-3’s (RRIPP-3) Study

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1854
Author(s):  
Bernadette P. Marriott ◽  
Travis H. Turner ◽  
Joseph R. Hibbeln ◽  
Jill C. Newman ◽  
Marcie Pregulman ◽  
...  
Keyword(s):  
United States ◽  
Controlled Trial ◽  
The United States ◽  
Military Officers ◽  
Krill Oil ◽  
Omega 3 ◽  
Double Blind ◽  
Significant Group ◽  
Intention To Treat ◽  
Improved Performance

Studies have assessed omega-3 fatty acids and cognitive decline among older adults and cognitive development among children, although less is known about cognitive or neurological effects among young adults. We examined whether omega-3 supplementation from krill oil could improve cognition and resilience among young military officers compared to a control. This double-blind, placebo-controlled trial enrolled 555 officers (mean age 23.4 ± 2.8, 98.6% male) entering the United States (US) Army Infantry Basic Officer Leaders Course (IBOLC) with the intention to complete the US Ranger Course. Volunteer participants consumed eight dietary supplements daily of krill oil containing 2.3 g omega-3 or control (macadamia nut oil) over an approximate 20-week period. Cognitive functioning, resilience, and mood were assessed during a well-rested period at approximately 14 weeks and after a battlefield simulation at 16 weeks. Blood spot samples were collected to monitor compliance and dietary intake was assessed. All hypotheses were tested using both ‘Intention to Treat’ (ITT) and ‘As Per Protocol’ (APP) approaches. Of the 555 randomized individuals, 245 (44.1%) completed the study. No statistically significant group-by-time interactions indicating treatment effect were found on any outcomes. Poor compliance was indicated by lower than expected omega-3 elevations in the treatment group, and may have contributed to a failure to detect a response.

scholarly journals Decline in Marriage Associated with the COVID-19 Pandemic in the United States

2020 ◽  
Vol 6 ◽  
pp. 237802312098032
Author(s):  
Brandon G. Wagner ◽  
Kate H. Choi ◽  
Philip N. Cohen
Keyword(s):  
United States ◽  
The United States ◽  
Cumulative Number ◽  
Short Term ◽  
Know How ◽  
The Social ◽  
Reporting Delays ◽  
Social Upheaval ◽  
Near Future ◽  
Do So

In the social upheaval arising from the coronavirus disease 2019 (COVID-19) pandemic, we do not yet know how union formation, particularly marriage, has been affected. Using administration records—marriage certificates and applications—gathered from settings representing a variety of COVID-19 experiences in the United States, the authors compare counts of recorded marriages in 2020 against those from the same period in 2019. There is a dramatic decrease in year-to-date cumulative marriages in 2020 compared with 2019 in each case. Similar patterns are observed for the Seattle metropolitan area when analyzing the cumulative number of marriage applications, a leading indicator of marriages in the near future. Year-to-date declines in marriage are unlikely to be due solely to closure of government agencies that administer marriage certification or reporting delays. Together, these findings suggest that marriage has declined during the COVID-19 outbreak and may continue to do so, at least in the short term.

scholarly journals Efficacy and safety of fremanezumab in patients with migraine and inadequate response to prior preventive treatment: subgroup analyses by country of a randomized, placebo-controlled trial

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Egilius L. H. Spierings ◽  
Mikko Kärppä ◽  
Xiaoping Ning ◽  
Joshua M. Cohen ◽  
Verena Ramirez Campos ◽  
...  
Keyword(s):  
United States ◽  
Czech Republic ◽  
Adverse Events ◽  
Least Squares ◽  
The United States ◽  
Inadequate Response ◽  
Double Blind ◽  
Monthly Average ◽  
Preventive Medication ◽  
Subgroup Analyses

Abstract Background The FOCUS study evaluated the efficacy of migraine preventive medications across different countries within the same patient population, particularly for patients with difficult-to-treat migraine. These prespecified subgroup analyses evaluated efficacy by country in the FOCUS study of fremanezumab in adults with episodic migraine or chronic migraine and documented inadequate response to 2 to 4 migraine preventive medication classes. Methods Overall, 838 participants were enrolled in the FOCUS study, a randomized, double-blind, placebo-controlled, parallel-group, phase 3b study performed at 104 sites. For 12 weeks of double-blind treatment, patients were randomized (1:1:1) to quarterly fremanezumab, monthly fremanezumab, or matched placebo. The primary efficacy endpoint was the mean change from baseline in monthly average migraine days over 12 weeks of double-blind treatment, evaluated by country in these subgroup analyses. Results Of 14 countries contributing data, the Czech Republic (n = 188/838; 22%), the United States (n = 120/838; 14%), and Finland (n = 85/838; 10%) enrolled the most patients. Changes from baseline in monthly average migraine days over 12 weeks were significantly greater with fremanezumab versus placebo for patients in these countries: Czech Republic (least-squares mean difference versus placebo [95% confidence interval]: quarterly fremanezumab, − 1.9 [− 3.25, − 0.47]; P = 0.009; monthly fremanezumab, − 3.0 [− 4.39, − 1.59]; P < 0.001), the United States (quarterly fremanezumab, − 3.7 [− 5.77, − 1.58]; P < 0.001; monthly fremanezumab, − 4.2 [− 6.23, − 2.13]; P < 0.001), and Finland (quarterly fremanezumab, − 3.0 [− 5.32, − 0.63]; P = 0.014; monthly fremanezumab, − 3.9 [− 6.27, − 1.44]; P = 0.002). Results were comparable for the remaining 9 countries, with the least-squares mean difference versus placebo ranging from – 5.6 to – 2.4 with quarterly fremanezumab and from − 5.3 to − 1.5 with monthly fremanezumab. Incidences of serious adverse events and adverse events leading to discontinuation were low and comparable across countries and treatment groups. Conclusions Monthly and quarterly fremanezumab significantly reduced the monthly average number of migraine days versus placebo regardless of country and continent (North America versus Europe) in migraine patients with documented inadequate response to 2 to 4 migraine preventive medication classes. Trial registration ClinicalTrials.gov Identifier: NCT03308968.

scholarly journals Du projet stratégique sino-soviétique au projet stratégique sino-américain : la Nouvelle Chine en quête d’une stratégie d’accès à l’influence planétaire

2005 ◽  
Vol 10 (4) ◽  
pp. 757-795
Author(s):  
Claude Cadart
Keyword(s):  
United States ◽  
Foreign Policy ◽  
The United States ◽  
Chinese Foreign Policy ◽  
Cultural Dimension ◽  
Deng Xiaoping ◽  
White House ◽  
Strategic Project ◽  
Near Future

« From the Sino-Soviet strategic project to the Sino-American strategic project » is a purposely schematic interpretative essay on the evolution of Chinese foreign policy from 1949 to 1979 with emphasis on, the latter phase of that evolution, that of the 1969—1979 period, and more particularly on the last year of that decade, 1979. The project, both defensive and offensive, of American and Chinese co-leadership of the planet that Mao had undertaken to carry out in 1971-1972 with the encouragement of Nixon had to be more or less put aside from 1973 to 1978 because of the seriousness of the domestic crises that were successively shaking both China and the United States during those years. In 1978—79, it was able to be reactivated by Deng Xiaoping who sought, with the benediction of the White House, to add an economic and a cultural dimension to Us diplomatic and strategic dimension. It is unlikely however in the near future that the United States will consider China as other than an auxiliary aspect of the fundamental game of their relations with the most powerful of their adversary-partners, the U.S.S.R. As in the case of the Sino-Soviet strategic project that China promoted from 1949 to 1959, the Sino-American strategic project that China has sought to « sell » the United States since 1969 has not, therefore, much chance of success.

scholarly journals A FRESH LOOK AT KNOWLEDGE MANAGEMENT STRATEGIES DURING THE CRISIS

2021 ◽  
Author(s):  
Marharyta Chepeliuk
Keyword(s):  
United States ◽  
Digital Technology ◽  
Management Strategies ◽  
The United States ◽  
Office Work ◽  
Remote Work ◽  
High Recovery ◽  
The Social ◽  
Employment Rates ◽  
Near Future

The pandemic has enhanced the social function of digital technologies and services. It is solely through digital technology that a massive shift to remote work has been possible during the most difficult period of the pandemic. All over the world, the philosophy of office work is changing, and there is a transition to permanent and conditional-permanent remote work. For example, Transport Canada is planning to move to telecommuting as a key employment model for its employees. In the near future, telecommuting will continue for most of the 6,000 employees in the agency. In China, widespread use of WeChat, Tencent, and Ding digital working applications began in late January 2020, when isolation measures were introduced. In Switzerland, COOVID-19 Remote Work and Study Resources provides free resources for remote operation and distance learning. Zoom and Google Meet videoconferencing, remote workplaces, and new social platforms run remote work almost immediately, and this trend is likely to continue after the lifting of the quarantine. Trends in staff employment worldwide are rather mixed. According to LinkedIn, it is possible to track changes in the employment rates of seven key economies – Australia, China, France, Italy, Singapore, Great Britain and United States. In France and Italy, the decline was more pronounced at -70% and -64.5% respectively by mid-April 2020. Since then, employment has been gradually recovering, and most of the seven key economies for which these figures have been analysed tend to change by 0 per cent year on year. By July 1, 2020, China, France, and the United States had seen the largest rebound in relative recruitment – -6% or -7%. At the end of September 2020, the countries with a high recovery in employment were China (22 per cent), Brazil (13 per cent), Singapore (8 per cent) and France (5 per cent). In these economies, hiring so far seems to compensate for months in which no new personnel have been recruited, indicating some stabilization of the labor market.

scholarly journals Assessing the influence of an extended hurricane season on inland flooding potential in the Southeast United States

2016 ◽  
Author(s):  
Monica H. Stone ◽  
Sagy Cohen
Keyword(s):  
United States ◽  
Tropical Cyclones ◽  
Climate Warming ◽  
Global Climate ◽  
River Basins ◽  
The United States ◽  
Southeast United States ◽  
Global Climate Warming ◽  
Hurricane Season ◽  
Near Future

Abstract. Recent tropical cyclones, like Hurricane Katrina, have been some of the worst the United States has experienced. Tropical cyclones are expected to intensify, bringing about 20 % more precipitation, in the near future in response to global climate warming. Further, global climate warming may extend the hurricane season. This study focuses on four major river basins (Neches, Pearl, Mobile, and Roanoke) in the Southeast United States that are frequently impacted by tropical cyclones. An analysis of the timing of tropical cyclones that impact these river basins found that most occur during the low discharge season, and thus rarely produce riverine flooding conditions. However, an extension of the current hurricane season of June–November, due to global climate warming, could encroach upon the high discharge seasons in these basins, increasing the susceptibility for riverine hurricane-induced flooding. This analysis shows that an extension of the hurricane season to May–December (just 2 months longer) increased the number of days that would be at risk to flooding were the average tropical cyclone to occur by 37–258 %, depending on the timing of the hurricane season in relation to the high discharge seasons on these rivers. Future research should aim to extend this analysis to all river basins in the United States that are impacted by tropical cyclones in order to provide a bigger picture of which areas are likely to experience the worst increases in flooding risk due to a probable extension of the hurricane season with expected global climate change in the near future.

METHADONE AND CHILDREN

PEDIATRICS ◽  
1971 ◽  
Vol 48 (2) ◽  
pp. 173-175
Author(s):  
Saul Blatman
Keyword(s):  
United States ◽  
Urban Areas ◽  
Methadone Maintenance ◽  
The United States ◽  
Heroin Addiction ◽  
Analgesic Drug ◽  
Heroin Addicts ◽  
Near Future

The increasing use of methadone maintenance (substitution) programs1-3 in the treatment of adult heroin addiction has created situations for children which require the attention of pediatricians. Methadone is an analgesic drug. In urban areas, thousands of heroin addicts are now receiving high dosage of methadone, usually 80 to 120 mg daily. This approach to heroin addiction has met with greater success than any other form of treatment. It is expected that increasing numbers of heroin addicts will be treated in the near future by this method throughout the United States and Canada.4 Pediatricians should focus on three aspects of the problem as follows:

Acquisition of Nationality in the Emergency Refugee Shelter

1945 ◽  
Vol 39 (1) ◽  
pp. 13-19
Author(s):  
Albert G. D. Levy
Keyword(s):  
United States ◽  
New York ◽  
The United States ◽  
The State ◽  
United States Government ◽  
Immigrant Status ◽  
American Citizenship ◽  
States Government ◽  
Free Port ◽  
Near Future

Several families now living in the Emergency Refugee Shelter which the United States Government has established at Fort Ontario, in the state of New York, are expecting the birth of children in the near future. Will these children acquire American citizenship jure soli? Does the non-immigrant status of the parents derogate from the privilege of the children? And most important among the numerous questions involved, Does the so-called “refugee free port” constitute the requisite type of American territory?

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