Diagnosing Affective Disorder in Adolescents: The Use of the Schedule for Affective Disorders and Schizophrenia

1985 ◽  
Vol 30 (8) ◽  
pp. 605-608 ◽  
Author(s):  
S.P. Kutcher ◽  
G. Yanchyshyn ◽  
Carole Cohen

The Schedule for Affective Disorders and Schizophrenia was administered to 42 consecutively hospitalized psychiatrically disturbed adolescents. The SADS proved to be a good measure of current affective disorder and also identified a large number of adolescents with a positive past history of affective disorder. These patients had not been so identified by traditional assessment means. The use of a semi-structured interview is to be encouraged in the assessment period of psychiatrically disturbed adolescents and in further research at attempts to define the parameters of depressive disorders occurring in adolescents.

1992 ◽  
Vol 7 (2) ◽  
pp. 49-52 ◽  
Author(s):  
R Richards ◽  
DK Kinney ◽  
H Daniels ◽  
K Linkins

SummaryPreliminary new data support the enhancement of ‘everyday’ creativity among those persons with bipolar disorders who manifest milder rather than more severe mood elevations, and among certain individuals who are likely to carry bipolar liability but themselves show no clinical mood elevations – in this case, unipolar depressives with a family history of bipolar disorder, when compared with depressives lacking this history. Creativity was assessed using the lifetime creativity scales (Richards el al, 1988). Underlying mechanisms may be multifactorial and complex. Results suggest that both personal and family history should be considered when making predictions concerning creativity and affective disorders.


1994 ◽  
Vol 22 (2) ◽  
pp. 177-180
Author(s):  
Barbara Sahakian ◽  
Georgina Charlesworth

This single case history highlights the importance of a complete psychological assessment to establish a client's past history rather than simply implementing a behavioural approach for the presenting symptoms. A single session of bereavement work was effective in treating agoraphobia in an elderly lady with a history of affective disorder throughout her adult life.


1989 ◽  
Vol 154 (5) ◽  
pp. 705-708 ◽  
Author(s):  
C. P. Lucas ◽  
J. C. Rigby ◽  
S. B. Lucas

In a retrospective analysis of 100 cases of mania (1981–1985), the incidence of subsequent depression was found to be 30%. Its occurrence was significantly associated with three factors: cyclothymic premorbid personality, family history of affective disorder, and past history of depression. By discriminant analysis, outcome could be predicted successfully in 81% of cases.


2002 ◽  
Vol 21 (11) ◽  
pp. 623-629 ◽  
Author(s):  
A Tracqui ◽  
A Miras ◽  
A Tabib ◽  
J S Raul ◽  
B Ludes ◽  
...  

A fatal case of sildenafil citrate (Viagra1) overdosage is presented. The deceased was a 56-year old male found dead at home, with a past history of diabetes mellitus, hypertension, chronic alcoholism, anxio-depressive disorders, and erectile dysfunction. The main autopsy findings were cardiomegaly (650 g) with dilated cardiomyopathy, diffuse coronary atherosclerosis with no sign of acute ischaemic disease, and extensive fibrosis of the myocardium, especially affecting the cardiac conducting tissue. As measured by HPLC/MS, sildenafil concentration in postmortem blood (6.27 mg/mL) exceeded at least four times the highest therapeutic levels previously reported. The results are discussed in the light of the literature about the cardiovascular side effects of sildenafil, with special emphasis on the recently evidenced arrhythmogenic potential of the drug. This is the first report of a fatality caused by sildenafil overdosage.


1977 ◽  
Vol 40 (3_suppl) ◽  
pp. 1135-1141 ◽  
Author(s):  
Donald S. Schaeffer

Patients in an affective disorders clinic diagnosed unipolar ( n = 13), bipolar ( n = 10), or schizo-affective ( n = 7) disorder were given a Maudsley Neuroticism Scale, a Rorschach, and a form interview. Mood over the course of the procedure was assessed and speech content measured. Diagnostic groups differed on background measures of social competence, schizo-affectives being poorer than bipolar and unipolar subjects. Rorschach pathognomic verbalization scores for schizo-affective and bipolar subjects were poorer than for unipolar subjects. Rorschach form definiteness for schizo-affectives was poorer than for bipolar and unipolar subjects. Neuroticism scores did not discriminate diagnostic groups but correlated with mood ratings. History of mania was associated with symbolic bizarreness, resembling schizo-affective disorder. However, the social competence and perceptual maturity of subjects with manic histories did not differ from those without.


2018 ◽  
Vol 8 (4) ◽  
pp. 27-33
Author(s):  
Nisha Khatri ◽  
Babita Thapa

Tuberculosis is a highly contagious infectious disease worldwide. Tuberculosis causes ill-health among millions of people each year and ranks as the second leading cause of death from an infectious disease worldwide. A descriptive exploratory study design was conducted among 106 middle adulthood Community people of Saptakoshi Municipality of Saptari District, between 2074/06/3 to 2074/06/1 using non-probability purposive sampling method, and data was collected using semi-structured interview schedule. More than half of the respondents (62.3%) were of the age group 40-49 years, nearly half (50.9%) were Female. Near about one fifth (19%) of the respondents had positive family history of tuberculosis. Majority of the respondents (98.1%) stated cause of tuberculosis as bacteria. Almost all the respondents were aware about the signs and symptoms of tuberculosis. Only 12.3% of the respondents were aware about DOTS Programme. A significant association (p=0.037) was revealed between level of awareness and Past history of previous exposure to Pulmonary Tuberculosis


1983 ◽  
Vol 143 (2) ◽  
pp. 133-138 ◽  
Author(s):  
K. O'Sullivan ◽  
P. Whillans ◽  
M. Daly ◽  
B. Carroll ◽  
A. Clare ◽  
...  

SummaryThree hundred male Irish alcoholics were selected from 508 consecutive alcoholic admissions to hospital. Using well defined diagnostic criteria, they were divided into three subgroups (1) primary alcoholics, (2) alcoholics with secondary affective disorder and (3) those with primary affective disorder and secondary alcoholism. Although the three groups reported differences in past history and family history of affective disorder and in time spent in hospital for both alcoholism and affective disorder, there was little to distinguish them in behaviour associated with alcoholism or in family history of alcoholism. The implications of these findings and their significance for the relationship of affective disorder and alcoholism are discussed.


The research is aimed to analysis of age-specific and gender-based risk factors for affective pathologies. Based on the population of the Kharkiv region, the population frequency of affective disorders was determined. It was calculated as probability for an individual to be affected throughout life and can be used for scientific purposes and genetic counseling. The age-specific cumulative frequencies were calculated, reflecting the risk for an individual to be affected in a specific period of life. They can be reference points in genealogical analysis. It has been shown that, despite a higher frequency in women, depressive disorders manifest earlier and tend to be more severe in men. That is, the female sex is a factor of increased risk, while affected men have a high background of genetic predisposition. To analyze risk factors, statistical material from specialized medical institutions of the Kharkiv region from 2010 to 2016 was used. The data were obtained from 1,199 patients who were hospitalized at the Institute of Neurology, Psychiatry and Narcology of the Academy of Medical Sciences of Ukraine, that is, they had extremely severe degrees of affective disorder and, probably, had a more significant genetic component in the structure of individual predisposition. The proportion of hospitalized women (74.9 %) was three times higher than the proportion of men (25.1 %) that significantly differs from the population sex ratio and indicates that the female sex is a factor of increased risk for affective pathology. The age of onset for affective disorders was lower in men than in women: bipolar disorder in males manifests 6 years earlier than in females, depressive episode – 2 years, recurrent depression – 5 years, chronic mood disorders – 4 years. On average, the difference between age of onset in women (46.6 years, 95% CI 45.7–47.5) and men (42.7 years, 95% CI 41.0–44.3) is 4 years. The maximum risk of affective disorder in women is between the age of 50 and 60 years, in men there are two peaks – at 20–30 and 45–60 years. The population frequency, that is an indicator of the risk for an affective disorder in the population of the Kharkiv region, is 0.21 %. The probability of affective disorder for men is 0.15 %, for women this indicator is 1.7 times higher – 0.26 %.


2015 ◽  
Vol 11 (1) ◽  
pp. 180-185 ◽  
Author(s):  
Mauro Giovanni Carta ◽  
Alessandra Conti ◽  
Federica Lecca ◽  
Federica Sancassiani ◽  
Giulia Cossu ◽  
...  

Introduction: Aims: to measure the association between Celiac Disease (CD) and affective disorders, particularly Bipolar Disorder (BD), since it has not been studied yet, and to measure how much the quality of life (QoL) of a person with CD is affected by comorbidity with these disorders. Methods: Design: Case-control study. Cases: 60 consecutive patients with CD. Controls: 240 subjects without CD, randomly selected after sex- and age-matching from a database of an epidemiological study. Psychiatric diagnoses according to DSM-IV carried out by physicians using structured interview tools (ANTAS-SCID). QoL was measured by means of SF-12. Results: The lifetime prevalence of Major Depressive Disorder (MDD) was higher in CD than in controls (30.0% vs 8.3%, P<0.0001) as well as Panic Disorder (PD) (18.3% vs 5.4%, P<0.001) and BD (4.3% vs 0.4%, P<0.005). Patients with CD show a lower mean score than controls on SF12 (35.8±5.7 vs. 38.2±6.4; p=0.010), but those without comorbidity with MDD, PD and BD do not. The attributable burden of CD in worsening QoL - when comorbid with these disorders - was found comparable to that of serious chronic diseases like Wilson’s Disease, and lower than Multiple Sclerosis only. Conclusion: MDD, PD and BD are strictly associated with CD. The comorbidity with these disorders is the key determinant of impaired quality of life in CD. Thus a preventive action on mood and anxiety disorders in patients suffering from CD is required. Moreover a screening for CD in people with affective disorders and showing key symptoms or family history of CD is recommended.


1994 ◽  
Vol 9 (5) ◽  
pp. 241-248 ◽  
Author(s):  
JDC Mellers ◽  
N Marchand-Gonod ◽  
M King ◽  
V Laupa ◽  
JR Smith

SummaryPsychiatric morbidity was assessed in 55 HIV seropositive women who were attending either an HIV centre in Paris (n = 30) or a genitourinary clinic in London (n = 25). Demographic data and information concerning HIV disease, openness about diagnosis, counselling received, social and family support, sexual behaviour and attitudes towards fertility and pregnancy were recorded using a semi-structured interview. Moderate or severe levels of psychiatric distress were found in 60% of the women in Paris and 28% of those in London. Overall, these rates are higher than those found in comparable studies of HIV seropositive men. Psychiatric disorder was associated with a past history of intravenous drug use and older age. Over half of the women were in regular sexual relationships but safe sex precautions were frequently not used. Sixteen subjects among those of child bearing age were prepared to consider having children.


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