Subjective memory complaints in the elderly: Depressive symptoms and future dementia

1997 ◽  
Vol 171 (4) ◽  
pp. 373-376 ◽  
Author(s):  
B. Schmand ◽  
C. Jonker ◽  
M. I. Geerlings ◽  
J. Lindeboom
Keyword(s):  
Depressive Symptoms ◽  
Predictive Power ◽  
Mmse Score ◽  
The Elderly ◽  
Subjective Memory Complaints ◽  
Subjective Memory ◽  
Memory Complaints ◽  
Baseline Mmse Score ◽  
Premorbid Intelligence ◽  
Adult Reading

BackgroundPopulation studies indicate that subjective memory complaints by elderly people are correlated with cognitive performance. These complaints have some predictive power regarding the development of dementia. The present study attempted to replicate this finding, and investigated which variables determine subjective memory complaints.MethodParticipants in the Amsterdam Study of the Elderly (n=2114; 65–84 years of age), who were not demented and had a normal MMSE score (> 23) at baseline, were re-examined after four years. Subjective complaints were measured using a previously developed scale. Dementia and depression were measured using the Geriatric Mental State Schedule (GMS). Premorbid intelligence was measured by the Dutch Adult Reading Test (DART)ResultsMemory complaints at baseline contributed a small but significant amount of diagnostic information with respect to the prediction of future dementia. Depressive symptoms at baseline had no predictive value when these memory complaints were accounted for. Subjective memory complaints were associated with depression, baseline MMSE score, and premorbid intelligence.ConclusionsSubjective memory complaints are not just secondary to depression, but in part reflect realistic self-observations of cognitive decline.

scholarly journals Symptoms of Depression in a Large Healthy Population Cohort are related to Subjective Memory Complaints and Memory Performance in Negative Contexts

2017 ◽  
Author(s):  
Susanne Schweizer ◽  
Rogier A. Kievit ◽  
Tina Emery ◽  
Richard N. Henson ◽  
Keyword(s):  
Depressive Symptoms ◽  
General Population ◽  
Memory Performance ◽  
Large Population ◽  
Healthy Population ◽  
Subjective Memory Complaints ◽  
Subjective Memory ◽  
Symptoms Of Depression ◽  
Memory Complaints ◽  
The Impact

AbstractDecades of research have investigated the impact of clinical depression on memory, which has revealed biases and in some cases impairments. However, little is understood about the effects of sub-clinical symptoms of depression on memory performance in the general population. Here we report the effects of symptoms of depression on memory problems in a large population-derived cohort (N = 2544), 87% of whom reported at least one symptom of depression. Specifically, we investigate the impact of depressive symptoms on subjective memory complaints, objective memory performance on a standard neuropsychological task and, in a subsample (n = 288), objective memory in affective contexts. There was a dissociation between subjective and objective memory performance, with depressive symptoms showing a robust relationship with self-reports of memory complaints, even after adjusting for age, gender, general cognitive ability and symptoms of anxiety, but not with performance on the standardised measure of verbal memory. Contrary to our expectations, hippocampal volume (assessed in a subsample, n = 592) did not account for significant variance in subjective memory, objective memory or depressive symptoms. Nonetheless, depressive symptoms were related to poorer memory for pictures presented in negative contexts, even after adjusting for memory for pictures in neutral contexts. Thus the symptoms of depression, associated with subjective memory complaints, appear better assessed by memory performance in affective contexts, rather than standardised memory measures. We discuss the implications of these findings for understanding the impact of depressive symptoms on memory functioning in the general population.

Subjective Memory Complaints and Mild Cognitive Impairment

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1 ◽  
Author(s):  
M. Simoes ◽  
L.C. Castro ◽  
O. Ribeiro ◽  
T. Salgado ◽  
C. Paz
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
The Elderly ◽  
Future Research ◽  
Older Individuals ◽  
Subjective Memory Complaints ◽  
Subjective Memory ◽  
Cross Sectional ◽  
Memory Complaints ◽  
Increased Risk

Background:Subjective Memory Complaints (SMC) are common in clinical practice. the clinical significance of these subjective complaints among older individuals is not well understood.Aim:To study and discuss the association between SMC and MCI, underlining the importance of an adequate clinical assessment of SMC in the elderly.Methods:Review of the literature.Results:There is no consistent definition of SMC in the literature. Some prospective studies showed an association with objective memory impairments, conceptualizing SMC as a Pre-Mild Cognitive Impairment. SMC are also currently considered to be a core feature of Mild Cognitive Impairment (MCI). Cross-sectional studies and longitudinal studies showed conflicting results concerning the association between SMC and MCI.Discussion:The understanding of the predictive value of SMC in cognitive decline is still poorly understood. It is important to define criteria aimed to increase specificity of memory complaints, allowing an earlier identification of populations with higher risk of MCI. Future research on this complex association is important to identify SMC individuals at increased risk of conversion to MCI and dementia.

scholarly journals Symptoms of depression in a large healthy population cohort are related to subjective memory complaints and memory performance in negative contexts

2017 ◽  
Vol 48 (1) ◽  
pp. 104-114 ◽  
Author(s):  
S. Schweizer ◽  
R. A. Kievit ◽  
T. Emery ◽  
R. N. Henson ◽  
Keyword(s):  
Depressive Symptoms ◽  
General Population ◽  
Memory Performance ◽  
Large Population ◽  
Healthy Population ◽  
Subjective Memory Complaints ◽  
Subjective Memory ◽  
Symptoms Of Depression ◽  
Memory Complaints ◽  
The Impact

BackgroundDecades of research have investigated the impact of clinical depression on memory, which has revealed biases and in some cases impairments. However, little is understood about the effects of subclinical symptoms of depression on memory performance in the general population.MethodsHere we report the effects of symptoms of depression on memory problems in a large population-derived cohort (N= 2544), 87% of whom reported at least one symptom of depression. Specifically, we investigate the impact of depressive symptoms on subjective memory complaints, objective memory performance on a standard neuropsychological task and, in a subsample (n= 288), objective memory in affective contexts.ResultsThere was a dissociation between subjective and objective memory performance, with depressive symptoms showing a robust relationship with self-reports of memory complaints, even after adjusting for age, sex, general cognitive ability and symptoms of anxiety, but not with performance on the standardised measure of verbal memory. Contrary to our expectations, hippocampal volume (assessed in a subsample,n= 592) did not account for significant variance in subjective memory, objective memory or depressive symptoms. Nonetheless, depressive symptoms were related to poorer memory for pictures presented in negative contexts, even after adjusting for memory for pictures in neutral contexts.ConclusionsThus the symptoms of depression, associated with subjective memory complaints, appear better assessed by memory performance in affective contexts, rather than standardised memory measures. We discuss the implications of these findings for understanding the impact of depressive symptoms on memory functioning in the general population.

scholarly journals Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study

2021 ◽  
Vol 18 (23) ◽  
pp. 12786
Author(s):  
Franziska Dinah Welzel ◽  
Melanie Luppa ◽  
Alexander Pabst ◽  
Michael Pentzek ◽  
Angela Fuchs ◽  
...  
Keyword(s):  
Risk Factors ◽  
Depressive Symptoms ◽  
Potential Risk ◽  
Oldest Old ◽  
Anxiety Symptoms ◽  
Subjective Memory Complaints ◽  
Subjective Memory ◽  
Memory Complaints ◽  
Potential Risk Factors

Research on anxiety in oldest-old individuals is scarce. Specifically, incidence studies based on large community samples are lacking. The objective of this study is to assess age- and gender-specific incidence rates in a large sample of oldest-old individuals and to identify potential risk factors. The study included data from N = 702 adults aged 81 to 97 years. Anxiety symptoms were identified using the short form of the Geriatric Anxiety Inventory (GAI-SF). Associations of potential risk factors with anxiety incidence were analyzed using Cox proportional hazard models. Out of the N = 702 older adults, N = 77 individuals developed anxiety symptoms during the follow-up period. The incidence rate was 51.3 (95% CI: 41.2–64.1) per 1000 person-years in the overall sample, compared to 58.5 (95% CI: 43.2–72.4) in women and 37.3 (95% CI: 23.6–58.3) in men. Multivariable analysis showed an association of subjective memory complaints (HR: 2.03, 95% CI: 1.16–3.57) and depressive symptoms (HR: 3.20, 95% CI: 1.46–7.01) with incident anxiety in the follow-up. Incident anxiety is highly common in late life. Depressive symptoms and subjective memory complaints are major risk factors of new episodes. Incident anxiety appears to be a response to subjective memory complaints independent of depressive symptoms.

scholarly journals Association of depressive symptoms and subjective memory complaints with the incidence of cognitive impairment in older adults with high blood pressure

2019 ◽  
Vol 10 (3) ◽  
pp. 413-420 ◽  
Author(s):  
Miguel Germán Borda ◽  
José Manuel Santacruz ◽  
Dag Aarsland ◽  
Sandy Camargo-Casas ◽  
Carlos Alberto Cano-Gutierrez ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Older Adults ◽  
Cognitive Impairment ◽  
Depressive Symptoms ◽  
High Blood Pressure ◽  
Subjective Memory Complaints ◽  
Subjective Memory ◽  
Memory Complaints

scholarly journals SUBJECTIVE MEMORY COMPLAINTS AND COGNITIVE PERFORMANCE: THE MODERATING ROLE OF DEPRESSIVE SYMPTOMS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S654-S654
Author(s):  
Elizabeth A Gallagher
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Episodic Memory ◽  
Cognitive Performance ◽  
Memory Performance ◽  
Health Concern ◽  
Subjective Memory Complaints ◽  
Subjective Memory ◽  
Memory Complaints ◽  
The Relationship

Abstract Cognitive health is a rising public health concern in the U.S. Currently, approximately 5.7 million older adults suffer from Alzheimer’s disease (AD), and by the year 2050 this number is expected to increase to 14 million. Subjective memory complaints (SMC) are shown to be an early indicator of cognitive decline, and accordingly included as a clinical criterion for diagnoses of MCI, an indicator of pre-dementia states, and a research criterion for AD diagnoses. Among older adults, depressive symptoms hinder the accuracy of memory self-ratings. However, there has yet to be consensus regarding the nature of how depressive symptoms may condition the relationship between SMC and cognitive performance. The aims of the present study are to both investigate whether SMC is related to episodic memory and to determine whether depressive symptoms act as a moderator for the relationship between SMC and episodic memory among older adults. This research used nationally representative sample of 8,123 older adults aged 65 and older who completed the Leave Behind Questionnaire in the 2012 and 2014 waves of the Health and Retirement Study. Linear regression was performed and results showed that there was a significant main effect of SMC on episodic memory performance, in that older adults with increased SMC have worse episodic memory. There was also a significant moderating effect of depressive symptoms, in that depressive symptoms cause older adults to underestimate their memory abilities. In order to use SMC as a tool for early detection efforts it is critical to understand these complex relationships.

scholarly journals Subjective memory complaints in the elderly may be related to factors other than cognitive deficit

2010 ◽  
Vol 4 (1) ◽  
pp. 54-57 ◽  
Author(s):  
Ana Cristina Procópio de Oliveira Aguiar ◽  
Miriam Ikeda Ribeiro ◽  
Alessandro Ferrari Jacinto
Keyword(s):  
Rating Scale ◽  
Care Facility ◽  
The Elderly ◽  
Cognitive Status ◽  
Subjective Memory Complaints ◽  
Subjective Memory ◽  
Extrinsic Factors ◽  
Term Care ◽  
Memory Complaints ◽  
Significant Difference

Abstract Prevalence of subjective memory complaints (SMC) in elderly community dwellers (ECD) ranges from 25 to 50%. Some controversy exists over the association between SMC and cognitive status. Objective: We investigated whether a correlation in cognitive performance existed between two different groups according to SMC. Methods: The Mini Mental State Examination (MMSE) and Dementia Rating Scale-Mattis (DRS-Mattis) were applied to two groups: ECD (n=14) with SMC and residents (n=14) of a long-term care facility (LTCF) without SMC. Results: The median age in the ECD group was 81.0 years, and in the LTCF group was 75.0 years. There was a statistically significant difference (p=0.048) between these groups regarding age. Concerning schooling (1-8 or ³9 years), there was no statistically significant difference between the groups (p=0.638). No statistically significant difference between the two groups was found for scores on the cognitive tests. Conclusion: SMC might be related to extrinsic factors other than insipient cognitive decline.

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