scholarly journals The adverse consequences of mephedrone use: a case series

2011 ◽  
Vol 35 (6) ◽  
pp. 203-205 ◽  
Author(s):  
Kirsty Mackay ◽  
Mark Taylor ◽  
Neeraj Bajaj

Aims and methodMephedrone is a cathinone with amphetamine-like stimulant effects, and is a commonly used recreational drug. The adverse effects of mephedrone use have not been extensively studied. All individuals who self-presented between January and June 2010 to the emergency departments and acute mental health services in Edinburgh and Falkirk with adverse effects of self-reported mephedrone use were identified.ResultsTwenty cases were identified and analysed. Severe agitation was the most common presenting problem (70%), with 40% of individuals developing psychotic symptoms and a further 20% reporting low mood and suicidality. One person died by suicide.Clinical implicationsMephedrone can produce amphetamine-like adverse psychological intoxication effects, particularly in those with a history of mental illness. Clinicians should consider advising patients on the adverse effects of mephedrone, where relevant.

2013 ◽  
Vol 37 (2) ◽  
pp. 44-48 ◽  
Author(s):  
John Lally ◽  
Emam-El Higaya ◽  
Zafar Nisar ◽  
Emma Bainbridge ◽  
Brian Hallahan

Aims and methodTo examine the prevalence of head shop drug usage in individuals attending a range of adult mental health services. We examined the effect of head shop drug usage on the mental state of individuals with a range of mental health disorders. Clinical data were obtained from 608 consecutively reviewed individuals attending adult mental health services in relation to their use of head shop and psychoactive drugs and the putative effects of head shop drugs on their mental state.ResultsThe prevalence of head shop drug use was 13% (n= 78), with a higher prevalence of usage noted in individuals younger than 35 years of age (25%). A large proportion of individuals (n= 41, 54%) reported adverse effects of these agents on their mental state, with psychotic symptoms being the most prevalent.Clinical implicationsHead shop drug usage was associated with a reported deleterious effect on mental state, which was particularly evident for individuals with a history of psychosis.


2011 ◽  
Vol 198 (6) ◽  
pp. 485-489 ◽  
Author(s):  
Nicola Swinson ◽  
Sandra M. Flynn ◽  
David While ◽  
Alison Roscoe ◽  
Navneet Kapur ◽  
...  

BackgroundThe rise in homicides by those with serious mental illness is of concern, although this increase may not be continuing.AimsTo examine rates of mental illness among homicide perpetrators.MethodA national consecutive case series of homicide perpetrators in England and Wales from 1997 to 2006. Rates of mental disorder were based on data from psychiatric reports, contact with psychiatric services, diminished responsibility verdict and hospital disposal.ResultsOf the 5884 homicides notified to the National Confidential Inquiry into Suicide and Homicide by People with Mental Illness between 1997 and 2006, the number of homicide perpetrators with schizophrenia increased at a rate of 4% per year, those with psychotic symptoms at the time of the offence increased by 6% per year. The number of verdicts of diminished responsibility decreased but no change was found in the number of perpetrators receiving a hospital order disposal. The likeliest explanation for the rise in homicide by people with psychosis is the misuse of drugs and/or alcohol, which our data show increased at a similar magnitude to homicides by those with psychotic symptoms. However, we are unable to demonstrate a causal association. Although the Poisson regression provides evidence of an upward trend in homicide by people with serious mental illness between 1997 and 2006, the number of homicides fell in the final 2 years of data collection, so these findings should be treated with caution.ConclusionsThere appears to be a concomitant increase in drug misuse over the period, which may account for this rise in homicide. However, an increase in the number of people in contact with mental health services may suggest that access to mental health services is improving. Previous studies have used court verdicts such as diminished responsibility as a proxy measure of mental disorder. Our data indicate that this does not reflect accurately the prevalence of mental disorder in this population.


2021 ◽  
Vol 15 (06) ◽  
pp. 787-790
Author(s):  
Hana Khairina Putri Faisal ◽  
Feni Fitriani Taufik ◽  
Tribowo Tuahta Ginting Sugihen ◽  
Prasenohadi ◽  
Tomu Juliani ◽  
...  

Introduction: COVID-19 pandemic affects mental health globally. Reports showed the increase of mental illness as a response to the COVID-19 pandemic. However, the correlation between the COVID-19 and mental illness is not fully understood yet. Methodology: We reported a brief psychotic disorder in a COVID-19 patient with no history of mental illness who was hospitalized in Persahabatan Hospital, Jakarta, Indonesia. Results: Psychotic symptoms appeared five days after COVID-19 onset and laboratory tests showed elevated levels of d-dimer and fibrinogen. Conclusions: Elevated levels of d-dimer and fibrinogen suggest an ongoing COVID-19-associated coagulopathy that might cause a microdamage in the central nervous system. It might contribute to the manifestation of psychotic symptoms. The correlation between brief psychotic disorder and COVID-19 requires further investigation.


2015 ◽  
Vol 21 (2) ◽  
pp. 5 ◽  
Author(s):  
Rishie Kumar Parshotam ◽  
Pierre M Joubert

<p><strong>Background</strong>. Cannabis use may trigger or perpetuate clinical features of schizophrenia in vulnerable individuals, thereby contributing to the morbidity of schizophrenia and its burden of disease. These findings have mostly not considered the views of schizophrenia patients on cannabis use and its effect on their mental health.  </p><p><strong>Methods</strong>. A semi-structured 16-point opinion-type questionnaire was formulated from the results of a previous qualitative study on schizophrenia patients’ opinions about cannabis use. The questionnaire was applied to 60 participants from an inpatient schizophrenia population at Weskoppies Hospital, Pretoria, South Africa, who had a <em>Diagnostic and Statistical Manual of Mental Disorders</em>, 4th edition (text revision) (DSM-IV-TR) diagnosis of schizophrenia and a documented history of cannabis use. </p><p><strong>Results</strong>. According to participants’ responses, 61.7% admitted to suffering from a mental illness, 95.0% admitted to using cannabis in the past, and 20.0% of participants admitted to the current use of cannabis. Over half (51.7%) of the participants responded that cannabis had adverse effects on their mental health, 26.7% that their mental illness was caused by using an illicit drug other than cannabis, 26.7% that only impure cannabis had adverse effects on their mental health, and 48.3% that only using too much cannabis had bad effects on their mind. A high percentage (58.3%) of participants responded that cannabis use helped reduce tension, 56.7% that it helped reduce anxiety, 66.7% that it helped to lift their mood, 63.3% that it helped them to relax, 60.0% that it helped to relieve their boredom, 43.3% that it helped them feel more energetic, 58.3% that it helped them sleep better, 13.3% that it helped reduce auditory hallucinations, and 31.7% that the beneficial effects of cannabis outweighed its negative effects. </p><p><strong>Conclusion</strong>. Most of the participants who responded that they were not using cannabis currently had positive views about its effects on their mental health, despite responding that cannabis may have adverse effects on their mental health. This is a worrisome outcome, since those participants who feel that cannabis has more beneficial than detrimental effects might not remain abstinent.</p>


Author(s):  
Nicola Swinson ◽  
Jennifer Shaw

There is a widespread public perception of the mentally ill as violent. Until the early 1980s there was a consensus view that patients with severe mental illness were no more likely to be violent than the general population. Emerging evidence from various countries over the past two decades, however, has established a small, yet significant, association between mental illness and violence. There are 500–600 homicides annually in England and Wales. Perpetrators and victims are predominantly young males, especially when the victim is unknown to the perpetrator. In such ‘stranger homicides’ perpetrators are less likely to have a lifetime history of mental illness, symptoms of mental illness at the time of the offence, or contact with mental health services. Despite an increasing rate of homicides in the general population, convictions for infanticide and the rate of infant homicide has remained relatively constant, at around 4.5 per 100 000 live births. Infanticide has become a generic term for killing of infants, even though the criminal charge in England applies to a crime for which only a woman can be indicted. Multiple homicides, in particular serial homicides, have generated a great deal of public and media interest over recent decades yet this phenomenon is rare in the UK. The rarity of these events means that there is a lack of empirical evidence about the characteristics of perpetrators and victims in the UK, with most evidence emanating from the United States. Even then, however, there is an absence of systematic, robust evidence, with many studies being limited by small sample size. Around 1 in 10 perpetrators of homicide in England and Wales are female, which is consistent with data from other countries. Stranger homicide by females is rare. In one-quarter of cases the victims are the perpetrators’ own children and a current or former partner in over a third. Homicides perpetrated by the elderly are exceptionally rare. There is a well documented increased risk of violence in those with schizophrenia. The aim of the National Confidential Inquiry is to collect detailed clinical information on people convicted of homicide, focusing on those with a history of contact with mental health services. Nearly one in three Inquiry cases were seen during the week before the homicide, a similar proportion within 1–4 weeks and the remainder between 1–12 months. A substantial proportion had mental state abnormalities at final contact, often distress, depressive symptoms, hostility, or increased use of alcohol or drugs. Despite this immediate risk was judged to be low or absent in 88 per cent cases at the last contact.


2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S243-S243
Author(s):  
Mariapaola Barbato ◽  
Shaikha AlHumairi ◽  
Shorouk Nafie ◽  
Baraa A Dhuhair ◽  
Nadia T Dabbagh

Abstract Background Most mental health disorders begin to develop in adolescence and early adulthood. These disorders account for a significant portion of hospitalization and other societal costs. The United Arab Emirates (UAE) has a rapidly growing population, one-third of which is below 25 years of age. The UAE government has pointed at mental health as one of the areas requiring attention and has approved a strategic plan supporting mental health research, education and promotion with a specific focus on youth (Dubai Mental Health Strategy 2021). The current study represents the first investigation aimed at characterizing youth who access mental health services in the UAE (specifically Dubai). Methods Data was collected retrospectively from child psychiatry case records of inpatients who accessed the Mental Health Clinic at Rashid Hospital between 2011–2016. Patients who received a diagnosis of schizophrenia spectrum disorders, bipolar and related disorders, depressive disorders or anxiety disorders were included. From patients’ records, information collected included demographics, life stressors (related to family, friends, health, academic performance, or religion), duration of untreated illness (DUI), family history of mental illness, parents’ age and education, main diagnosis, presence/absence of psychotic features. Demographic information and family history had been acquired from patients and family members at the time of intake. Results The final sample (N=99; Age 12–19) included 47.5% local (UAE national) and 52.5% non-local patients. The frequency of life stressors did not differ across ethnic groups except for relationships with friends, which were less likely to be reported as a source of stress among UAE nationals (χ2=4.35; p=0.04) compared to other nationalities. Suicidal thoughts were less common in patients with psychotic features compared to patients without psychotic features (χ2=4.64; p=0.03). A diagnosis of Depression was more common in females than males (χ2=3.93; p&lt;.05) and was associated with more frequent suicidal thoughts (χ2=23.81; p&lt;0.001) and self-harm behavior (χ2=16.20; p&lt;0.001). Separate ANOVAs were conducted to explore the effect of different variables on DUI: results showed that presence of Psychotic features was associated with shorter DUI (F (1,55) =4.37; p&lt;0.05) while Self-harm was associated with longer DUI (F (1,70) =5.82; p&lt;0.05). Discussion To our knowledge, this is the first study attempting to describe youth who access mental health services in the urban multi-cultural context of Dubai. A number of interesting findings were highlighted. Relationships with friends were more likely to represent a source of stress for non-local than local patients, suggesting a possible role of adjustment and social stress in migrant/expatriate youth. Suicidal thoughts were more common in patients diagnosed with depressive disorders (somewhat expected) but less common in patients presenting psychotic features. Patients experiencing psychotic symptoms were accessing mental health services sooner (shorter DUI) compared to patients who did not experience psychotic symptoms, in line with previous literature. Interestingly, patients reporting self-harm behaviors had longer DUI. Several interpretations can be proposed, for example, it is possible that self-harm represented a copying strategy to temporarily “handle” mental illness and delay help seeking in our sample. Studies in support of this and alternative explanations will be discussed. Taken together, our study can be a useful start point to open prevention-focused mental health discussions in the UAE and lead to improved national policies to promote youth wellbeing in the region.


1991 ◽  
Vol 15 (7) ◽  
pp. 396-401 ◽  
Author(s):  
John Reed

Policy for mental health services in England is based on two straightforward principles. These are, first that care should be provided as locally to where a person lives as is reasonably possible, and secondly that treatment should be available in the least restrictive conditions that are compatible with the safety of the patient, of those looking after him and of the public at large. I make no apology for reviewing the history of policy and practice; it is not possible to understand the mental health services that we are trying to achieve for the future without understanding how the service has developed over the years. I shall use the mental illness service as an example – similar considerations apply to the mental handicap services.


1971 ◽  
Vol 2 (2) ◽  
pp. 138-145 ◽  
Author(s):  
William J. Horvath

As long as mental illness is regarded as primarily a behavioral disorder, current and foreseeable manpower shortages in psychiatry make it necessary to increase the participation of nonmedical personnel in the treatment process. The controversy between those advocating behavioral treatment and those favoring the medical model cannot be resolved due to the fact that our current knowledge of the biologic roots of mental illness is inadequate. A breakthrough in research in this area could resolve the argument and solve the manpower problem by transferring psychiatric disorders into physiologic disease susceptible to medical treatment. Alternative models for the delivery of mental health services can be developed to allow for different possibilities in the outcome of research. Additional data is needed, especially on the costs and effectiveness of future therapies, before an evaluation of programs can be carried out.


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