Longitudinal physical activity assessment in post-surgical gynecologic cancer patients.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e21582-e21582 ◽  
Author(s):  
Jessica Gorzelitz-Liebhauser ◽  
Erin S. Costanzo ◽  
Ryan J. Spencer ◽  
Meredith E. Rumble ◽  
Stephen L. Rose ◽  
...  

e21582 Background: Physical activity is a key determinant of health, and exercise can be effective for decreasing anxiety and depression and improving quality of life in cancer survivors. The primary aim of this study was to report the trajectory of physical activity over time for post-operative gynecologic cancer patients. The secondary aim was to identify correlates of total physical activity over time. Methods: The study population included patients who underwent surgery for endometrial (n = 80) or ovarian (n = 43) cancer and wore an accelerometer for a 3-day period at 1 week, 1 month and 4 months after surgery. Accelerometer data were captured during all waking hours and were transformed into categories of light, moderate and vigorous intensity physical activity. The outcome of interest was total minutes of moderate to vigorous intensity physical activity (MVPA) collected over the three day period at each time point, analyzed using a linear mixed effect model approach, assessing the correlates of age, body mass index (BMI), self-rated health, laparotomy vs. laparoscopic (endometrial only) and neoadjuvant chemotherapy yes/no (ovarian only). Results: Mean age was 58.8 ± 10.1 years with mean BMI of 35.5±10.3 kg/m2. Over each three-day period, patients performed 7 ± 12 minutes of total accumulated MVPA at 1 week, 20 ± 41 minutes of total MVPA at 1 month, and 25 ± 36 minutes at 4-months post-surgery (p = 0.01). Federal guidelines recommend approximately 70 minutes of moderate intensity activity over a three-day period to collect 150 minutes of moderate activity a week. Better self-rated health at baseline was associated with increased activity over time (p = 0.02). BMI, age, type of surgery or use of neoadjuvant chemotherapy did not predict physical activity in patients of either disease site. Conclusions: Physical activity increased over time for endometrial and ovarian cancer patients. Self-reported health at baseline was also positively associated with increased moderate-vigorous physical activity over time. There is insufficient evidence to show that BMI significantly contributes to changes in moderate-to-vigorous physical activity over time. Future research should address barriers to activity and novel interventions.

2012 ◽  
Vol 9 (1) ◽  
pp. 129-137 ◽  
Author(s):  
Stuart J. Fairclough ◽  
Nicola D. Ridgers ◽  
Gregory Welk

Background:Vigorous-intensity physical activity (VPA) may confer superior health benefits for children compared to moderate-intensity physical activity (MPA), but the correlates of MPA and VPA may differ. The study purpose was to investigate associations between selected enabling, predisposing, and demographic physical activity correlates, and MPA and VPA during weekdays and at weekends.Methods:Data were gathered from 175 children (aged 10 to 11 years). MPA and VPA were assessed using accelerometers. Correlates were measured at child and school levels. Multilevel analyses identified correlates that significantly predicted MPA and VPA.Results:Gender significantly predicted weekday MPA (P < .001), and weekend MPA (P = .022) and VPA (P = .035). Weekday VPA was predicted by gender (P < .001), indices of multiple deprivation score (P < .003), BMI (P = .018), and school playground area (P = .046).Conclusions:Gender was the most significant correlate of MPA and VPA. Children most likely to engage in weekday VPA were boys with lower deprivation scores and BMI values, with access to larger playground areas.


Author(s):  
Guillermo F López-Sánchez ◽  
Rubén López-Bueno ◽  
Alejandro Gil-Salmerón ◽  
Roksana Zauder ◽  
Maria Skalska ◽  
...  

Abstract Background This is the first study analyzing levels of physical activity in a sample of quarantined adults with chronic conditions. The aim of this study was to compare moderate- and vigorous-intensity physical activity levels in Spanish adults with chronic conditions before and during coronavirus disease 2019 (COVID-19) quarantine. Methods A cross-sectional online survey was administered during the COVID-19 quarantine in Spain. A total of 163 participants with chronic conditions (113 females and 47 males; age range 18–64 years) completed the survey. A total of 26 chronic conditions were included. Participants self-reported average minutes/day of moderate and vigorous physical activity before and during quarantine. Differences in moderate- and vigorous-intensity physical activity levels before and during COVID-19 quarantine (overall, by gender, by age, by number of chronic conditions and by each chronic condition) were assessed by Wilcoxon-signed rank test. Results During COVID-19 quarantine, there was a significant decrease of moderate-intensity physical activity in Spanish people with chronic conditions (in both males and females, in those aged 18–24, 25–34, 35–44 and 55–64 years, in those with multimorbidity, in those with one/two chronic condition/s, and in those diagnosed with asthma/hypercholesterolaemia/chronic skin disease/haemorrhoids). Also, there was a significant decrease of vigorous-intensity physical activity in Spanish males with chronic conditions and in those with multimorbidity. Conclusions These results should be considered to develop effective strategies of physical activity promotion targeting these specific groups when new quarantine or restriction measures are implemented, in order to avoid new significant decreases of physical activity in these vulnerable populations.


Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Joshua R Sparks ◽  
Xuewen F Wang

Background: Glucose concentrations in a fasted and during a glucose challenged state rely on different mechanisms for regulation. In a fasted state, hepatic regulation of glucose is important; while in a glucose challenged state, muscle glucose disposal becomes more important. Evidence suggests that physical activity of moderate or higher intensities can increase muscle glucose disposal during an insulin-stimulated state, but has less effect on hepatic insulin sensitivity. The purpose of this study was to examine the associations between glucose concentrations (fasting and after an oral glucose ingestion) and minutes of physical activity at moderate- and vigorous-intensity in a large population. Methods: The sample included 2,807 adults (47.4% male and 52.6% female) aged 18-80 years who participated in the National Health and Nutritional Examination Surveys (NHANES) from 2013-2014 and who did not take any diabetic medications. Minutes being physically active at moderate- and vigorous-intensities during work, and recreationally, were collected using the Physical Activity Questionnaire, which was based on the Global Physical Activity Questionnaire. Moderate-intensity physical activity was defined as any activity that caused a small increase in breathing or heart rate, while vigorous-intensity physical activity was defined as large increases in breathing or heart rate. Both intensities had to be performed for a minimum of 10 continuous minutes. Plasma glucose concentrations at fasting and 2 hours after consumption of a drink containing 75g glucose (2-hour glucose) were determined. Pearson product correlations were performed for analysis. Results: The population had 141±133 (mean±SD) minutes of moderate-intensity physical activity during work and 63±56 minutes recreationally, as well as 174±156 minutes of vigorous-intensity physical activity during work and 77±56 minutes recreationally. Minutes of vigorous-intensity physical activity performed during work was associated with 2-hour plasma glucose concentrations (r=0.15; p=0.045); this association was not affected after adjusting for age, race, and sex (p=0.049), but was no longer significant after BMI was also adjusted (p=0.059). Recreational or total minutes of vigorous-intensity physical activity, and moderate-intensity physical activity was not associated with 2-hour glucose (p>0.20). Additionally, none of the physical activity minutes was associated with fasting glucose (p>0.27). Conclusion: Self-reported vigorous-intensity physical activity during work was positively associated with 2-hour glucose, but not fasting glucose. The results are surprising. Further studies with objective physical activity measures are needed to examine the associations with fasting and 2-hour glucose.


Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Fan Ye ◽  
Li Zhou ◽  
Joseph Yeboah ◽  
Peter H Brubaker ◽  
Alain G Bertoni

Introduction: Heart failure (HF) is a growing public health problem which is the leading cause of hospitalization. About half of people who develop HF die within 5 years of diagnosis. Recent evidence suggests that physical inactivity may be an important risk for HF. However, the importance of physical activity in the prevention and treatment have not been adequately recognized. Self-reported physical activity can provide insights into the impact of lifestyle behaviors on mortality. The objective of this study was to determine the relationship between physical activity and HF in a nationally representative sample of United States (US) adults. Methods: The 2007-2016 National Health and Nutrition Examination Survey data collection cycles were used for this analysis. Participants aged 65 and older with HF were defined as those who answered “yes” to the question: “Has a doctor or other health professional ever told you that you had congestive HF?” Frequency and duration of self-reported moderate-intensity (“Days moderate recreational activities” and “Minutes moderate recreational activities”) and vigorous-intensity Days vigorous recreational activities” and “Minutes vigorous recreational activities”) physical activity were collected through questionnaires as well in all data cycles. We used 2018 Physical Activity Guidelines for Americans Older Adults, which recommended that most older adults (age≥65 years) participate in at least 150 minutes of moderate-intensity aerobic activity or 75 minutes of vigorous-intensity aerobic activity per week as our cut-off points for calculating moderate-to-vigorous physical activity. Results: Between 2007-2008 and 2015-2016, the percentage of US adults ≥65 years with HF increased from 2.76% to 3.69% (p=0.04). Although a similar percentage of participants who met the criteria of at least 150 minutes of moderate-intensity activity per week was noted in both groups from 2007 to 2016 (on average, HF: 56.9% vs. HF-free: 56.7%, respectively, p>0.05), more HF-free participants reported at least 75 minutes of vigorous-intensity recreational activities per week compared to HF participants in each calendar year (82.8% vs. 66.7%, 85.0% vs. 70.0%, 83.5% vs. 55.0%, 87.0% vs.75%, 85.2% vs. 63.6%, respectively, p<0.01). Additionally, among those who reported activities, older adults with HF were less than 20 times as likely to report moderate or vigorous recreational activities compared to those without HF. Conclusions: Our findings illustrate lower self-reported physical recreational activities, especially vigorous activities, in older participants who report a diagnosis of HF and more participants without HF report vigorous-intensity recreational activities. Future study should focus on understanding the physical limitations of HF patients, which is paramount in developing cardiac rehabilitation strategies to improve their function capacity.


2013 ◽  
Vol 10 (3) ◽  
pp. 437-450 ◽  
Author(s):  
Kelli L. Cain ◽  
James F. Sallis ◽  
Terry L. Conway ◽  
Delfien Van Dyck ◽  
Lynn Calhoon

Background:In 2005, investigators convened by the National Cancer Institute recommended development of standardized protocols for accelerometer use and reporting decision rules in articles. A literature review was conducted to document accelerometer methods and decision rule reporting in youth physical activity articles from 2005−2010.Methods:Nine electronic databases identified 273 articles that measured physical activity and/or sedentary behavior using the most-used brand of accelerometer (ActiGraph). Six key methods were summarized by age group (preschool, children, and adolescents) and trends over time were examined.Results:Studies using accelerometers more than doubled from 2005−2010. Methods included 2 ActiGraph models, 6 epoch lengths, 6 nonwear definitions, 13 valid day definitions, 8 minimum wearing day thresholds, 12 moderate-intensity physical activity cut points, and 11 sedentary cut points. Child studies showed the most variation in methods and a trend toward more variability in cut points over time. Decision rule reporting improved, but only 54% of papers reported on all methods.Conclusion:The increasing diversity of methods used to process and score accelerometer data for youth precludes comparison of results across studies. Decision rule reporting is inconsistent, and trends indicate declining standardization of methods. A methodological research agenda and consensus process are proposed.


2009 ◽  
Vol 34 (4) ◽  
pp. 707-715 ◽  
Author(s):  
Shirley N. Bryan ◽  
Peter T. Katzmarzyk

The purpose of this study was to determine the proportion of Canadian adults (aged 18–55 years) who met the guidelines for moderate and vigorous physical activity set out in Canada’s Physical Activity Guide to Healthy Active Living. Leisure-time physical activity energy expenditure from moderate- and vigorous-intensity activities was calculated using data from the National Population Health Surveys (1994–1998) and the Canadian Community Health Surveys (2001–2007). The prevalence was estimated for no leisure-time physical activity, meeting only the moderate guideline, meeting both the moderate and vigorous guidelines, and meeting the guidelines through a combination of moderate and vigorous activities. Logistic regression was used to determine the odds of meeting the guidelines by various demographic characteristics. The prevalence of no activity did not change appreciably over time, ranging from 6.5% to 10%, depending on the survey year. Reporting of no activity was more prevalent among older adults, those in lower income groups, and those with a body mass index (BMI) ≥30 kg·m–2. Overall, 65% of adults met the guidelines for physical activity in 2007, which has increased from 54% in 1994–1995. Men, younger adults, those with a higher income, and those with a lower BMI more often met the guidelines. Among all subgroups, meeting the guidelines was most often accomplished through participation in moderate-intensity activities. These findings should be considered when designing and implementing public health interventions that promote participation in daily physical activity.


2004 ◽  
Vol 7 (4) ◽  
pp. 557-562 ◽  
Author(s):  
Melvyn Hillsdon ◽  
Margaret Thorogood ◽  
Mike Murphy ◽  
Lesley Jones

AbstractBackground:As epidemiological studies have become more complex, demands for short, easily administered measures of risk factors have increased. This study investigates whether such a measure of physical activity is associated with the risk of death from all causes and death from specific causes.Methods:A prospective follow-up study of 11 090 men and women, aged 35–64 years, recruited from five UK general practices who responded to a postal questionnaire in 1989. Self-reported frequency of vigorous-intensity physical activity and data on confounding factors were collected at baseline survey. Death notifications up to 31 December 2001 were provided by the Office for National Statistics. The relative risk (and 95% confidence interval) of dying associated with each level of exposure to physical activity was estimated by the hazard ratio in a series of Cox regression models.Results:After > 10 years' follow-up there were 825 deaths among the 10 522 subjects with no previous history of angina or myocardial infarction. Participation in vigorous exercise was associated with a significantly lower risk of all-cause mortality. Similar associations were found for ischaemic heart disease and cancer mortality, although the relationships were not significant at the 5% level.Conclusions:Simple measures of self-reported vigorous physical activity are associated with the risk of future mortality, at least all-cause mortality in a somewhat selected group. Interpretation of the finding should be treated with caution due to the reliance on self-report and the possibility that residual confounding may underlie the associations. Because moderate-intensity physical activity is also beneficial to health, short physical activity questionnaires should include measures of such physical activity in the future.


2017 ◽  
Vol 29 (2) ◽  
pp. 213-219 ◽  
Author(s):  
Valderi Abreu de Lima ◽  
Luis Paulo Gomes Mascarenhas ◽  
Juliana Pereira Decimo ◽  
William Cordeiro de Souza ◽  
Anna Louise Stellfeld Monteiro ◽  
...  

The aim of this study was to evaluate the level of physical activity and cardiorespiratory fitness in teenagers with type 1 diabetes mellitus (T1D) in comparison with healthy scholar participants. Total of 154 teenagers (T1D = 45 and CON = 109). Height, weight, cardiorespiratory fitness (VO2max), and the level of physical activity by the Bouchard’s Physical Activity Record were measured, and glycated hemoglobin (HbA1c) in T1D. The VO2max was lower in the T1D (38.38 ± 7.54) in comparison with the CON (42.44 ± 4.65; p < .05). The VO2max had correlation with the amount of time of moderate-to-vigorous physical activity (r = .63; p = .0001) and an inverse correlation with sedentary activities (r= -0.46; p = .006). In the T1D the levels of HbA1c had an inverse correlation with the amount of time of moderate-to-vigorous physical activity (r= -0.34; p = .041) and correlation with the BMI z-score (r = .43; p = .017). Only 37,8% of the participants in the T1D reached the adequate amount of daily moderate-to-vigorous intensity physical activity, in the CON 81,7% reached the WHO’s recommendation. Conclusion: T1D had less cardiorespiratory capacity then healthy controls, the teenagers of T1D with lower BMI z-score and that dedicated a greater time in moderate-to-vigorous intensity physical activity demonstrated a better glycemic control.


2018 ◽  
Vol 50 (4) ◽  
pp. 715-721 ◽  
Author(s):  
HIROYUKI KIKUCHI ◽  
SHIGERU INOUE ◽  
I-MIN LEE ◽  
YUKO ODAGIRI ◽  
NORIE SAWADA ◽  
...  

2020 ◽  
Vol 6 (1) ◽  
pp. e000775
Author(s):  
Juan Pablo Rey Lopez ◽  
Angelo Sabag ◽  
Maria Martinez Juan ◽  
Leandro F M Rezende ◽  
Maria Pastor-Valero

ObjectiveTo examine whether vigorous-intensity physical activity confers additional reductions on all-cause and cause-specific mortality compared with moderate-intensity physical activity.DesignA systematic review (registered in PROSPERO CRD42019138995) and meta-analysis.Data sourcesThree electronic databases up to April 14 2020.Eligibility criteriaInclusion criteria were prospective studies that contained information about (1) moderate-intensity (3–5.9 metabolic equivalent tasks (METs)) and vigorous-intensity (≥6 METs) physical activities and (2) all-cause and/or cause-specific mortality. Exclusion criteria were prospective studies that (1) exclusively recruited diseased patients (eg, hypertensive patients and diabetics) or (2) did not account for total physical activity in their multivariable models (3) or did not adjust or exclude individuals with comorbidities at baseline or (4) used physically inactive participants as reference group.ResultsFive studies (seven cohorts using sex-specific results) were pooled into a meta-analysis. For all-cause mortality and controlling by total physical activity, vigorous-intensity physical activity (vs moderate) was not associated with a larger reduction in mortality (HR 0.95, 95% CI 0.83 to 1.09). After the exclusion of one study judged with critical risk of bias (Risk Of Bias in Non randomized Studies, ROBINS tool) from meta-analysis, results remained similar (HR 0.98, 95% CI 0.85 to 1.12). Due to the limited number of studies, meta-analyses for cancer and cardiovascular mortality were not performed.ConclusionsProspective studies suggest that, for the same total physical activity, both vigorous-intensity and moderate-intensity physical activities reduce all-cause mortality to the same extent. However, absence of evidence must not be interpreted as evidence of absence due to the existing methodological flaws in the literature.


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