Cardiovascular disease-related chronic conditions among Veterans Affairs colorectal cancer survivors: A matched case-control analysis.

2018 ◽  
Vol 36 (7_suppl) ◽  
pp. 4-4
Author(s):  
Leah L. Zullig ◽  
Valerie Smith ◽  
Jennifer Lindquist ◽  
Christina D. Williams ◽  
Morris Weinberger ◽  
...  

4 Background: The growing number of colorectal cancer (CRC) survivors often have multiple chronic conditions. Comparing CRC survivors and matched non-cancer controls, our objectives were to determine the odds of CRC survivors being diagnosed with CVD-related chronic conditions and their likelihood of control during the year after CRC diagnosis. Methods: We retrospectively identified patients diagnosed with non-metastatic CRC in the Veterans Affairs (VA) healthcare system from fiscal years 2009-2012 and matched each with up to 3 non-cancer control patients. We used logistic regression to assess differences in the likelihood of being diagnosed with CVD-related chronic conditions and control between CRC survivors and non-cancer controls. Results: We identified 9,758 CRC patients and matched them to 29,066 non-cancer controls. At baseline, 69.4% of CRC survivors and their matched controls were diagnosed with hypertension, 52.4% with hyperlipidemia, and 36.7% with diabetes. Compared to matched non-cancer controls, CRC survivors had 57% higher odds of being diagnosed with hypertension (OR = 1.57, 95% CI = 1.49-1.64) and 12% higher odds of poor blood pressure control (OR = 1.12, 95% CI 1.06-1.18) in the subsequent year. Compared to matched non-cancer control patients, CRC survivors had half the odds of being diagnosed with hyperlipidemia (OR = 0.50, 95% CI = 0.48-0.52) and higher odds of LDL control (OR 1.14, 95% CI 1.06-1.23). There were no significant differences between groups for diabetes diagnoses or control. Conclusions: Compared to non-cancer controls, CRC survivors have: 1) greater likelihood of being diagnosed with hypertension and worse blood pressure control in the year following diagnosis; 2) lower likelihood of being diagnosed with hyperlipidemia or LDL control; and 3) comparable diabetes diagnoses and control. There may be a need for hypertension control interventions targeting cancer survivors.

2020 ◽  
pp. 20-27
Author(s):  
O. Gizinger

The article presents the results of a research of evaluation of the effectiveness and safety of dietary supplements and control of blood pressure as a complex treatment in patients with the 1st and 2nd stages of arterial hypertension (AH). It was found that using the complex product blood pressure control stabilises systolic and diastolic blood pressure.


2009 ◽  
Vol 27 (15_suppl) ◽  
pp. 6535-6535
Author(s):  
K. Enright ◽  
M. Krzyzanowska

6535 Background: Cardiovascular disease is a major cause of morbidity and mortality in long-term survivors of cancer. Whereas the burden of cardiovascular disease has been described in cancer survivors, the control of modifiable cardiovascular risk factors in this population is unknown. Methods: We used the National Health and Nutrition Examination Survey (NHANES 1999–2006) data to examine the rate of control of modifiable cardiac risk factors amongst US cancer survivors compared with propensity matched adult controls with no history of cancer. The modifiable cardiac risk factors (blood pressure, cholesterol, BMI, exercise, smoking) were considered to be controlled if they met the AHA/ACC guideline recommendations. Results: A total of 1,227 cancer survivors and 3,672 age, sex, and comorbidity matched controls were identified, representing 11.9 million cancer survivors and 31.2 million controls. Compared to age, sex and comorbidity matched controls cancer survivors were more likely to be current smokers (34.5% vs. 28.8%, p = 0.021), and more likely to have their BMI at target (32.8% vs. 28.6%, p = 0.034). There was no significant difference in the rate of blood pressure control (69.4% vs. 69.2%, p = 0.88), cholesterol control (47.6% vs. 48.2%, p = 0.80) or adherence to exercise recommendations (24.4% vs. 24.6%, p = 0.89). Younger cancer survivors (age 20–40 y) were 2.8 times more likely to be smokers than controls, whereas older cancer survivors (age 60–80y) were 1.2 times more likely to be smokers than controls. Compared with recent cancer survivors (10 years from diagnosis) were more likely to have optimal blood pressure control (73.3% vs. 65.5%, p = 0.02), however there was no difference in smoking rates, cholesterol, exercise or weight control with duration of cancer survival. Conclusions: Overall the control of modifiable cardiac risk factors was similar between survivors and controls, but was suboptimal in both groups. This study identified smoking cessation, particularly amongst young cancers survivors, as an important area of focus for improvement in survivorship care. No significant financial relationships to disclose.


Author(s):  
Sarath Lekamwasam ◽  
Sanka Wijebandara ◽  
Vajira Lekamwasam

Aims: To validate Sinhala version of HLS-EU-Q16 and asses the relationship between level of health literacy and control of blood sugar among diabetics and blood pressure among hypertensives.  Study Design: This study evaluated the psychometric properties of Sinhala translation of HLS-EU-Q16 (HLS-EU-Q16-Sinhala) adhering to the standard methods. Following forward and backward translations, the Sinhala version of the questionnaire was applied to a group of 252 patients with chronic non-communicable diseases. Test-retest agreement was examined using a random subgroup of 120 patients. We assessed the association between the level of health literacy and the degree of glycaemic control among diabetics (n=1205, males 453) and blood pressure control among hypertensives (n=755, males 402) selected from outpatient department. Results: The HLS-EU-Q16-Sinhala total score ranged from 22 to 72 with mean(SD) of 52.1(7.7). The overall Cronbach alpha was 0.84 and the Corrected item-total correlation ranged from 0.32 to 0.60. The Interclass correlation coefficient (ICC) for the test-retest reliability was 0.65(95%CI; 0.55-0.71). Diabetics with “poor” glycaemic control had low HL (40.0) compared to those with “intermediate” (52.6) or “good” (52.1) control (P=.03), after adjusting for age, gender and education level. Similarly, hypertensives with “poor” blood pressure control had low HL (45.0) compared to “intermediate” (52.3) or “good” (53.5) control (P=.03), after adjusting for the same covariates. Conclusions: This study indicates that the psychometric indices of the Sinhala version of the HLS-EU-Q16 are adequate for it to be used to assess HL among Sinhala speaking subjects. Further, it shows that patients with poor HL fail to achieve their primary treatment goals in diabetes and hypertension. 


2017 ◽  
Vol 40 (11) ◽  
pp. 1055-1060 ◽  
Author(s):  
Hasan Rehman ◽  
Julia M. Akeroyd ◽  
David Ramsey ◽  
Sarah T. Ahmed ◽  
Anwar T. Merchant ◽  
...  

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