scholarly journals Age and gender specific lung cancer incidence and mortality in Hungary: Trends from 2011 through 2016.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e21572-e21572
Author(s):  
Gabriella Galffy ◽  
Zoltan Kiss ◽  
Krisztina Bogos ◽  
Judit Moldvay ◽  
Nora Bittner ◽  
...  

e21572 Background: No assessment was conducted describing the age and gender specific epidemiology of lung cancer (LC) prior to 2018 in Hungary, thus the objective of this study was to appraise the detailed epidemiology of lung cancer (ICD-10 C34) in Hungary based on a retrospective analysis of the National Health Insurance Fund database. Methods: This longitudinal study included patients aged ≥20 years with LC diagnosis (ICD-10 C34) between 1st January 2011 and 31th December 2016. Patients with different cancer-related codes 6 months before or 12 months after LC diagnosis or having any anti-cancer treatment different from lung cancer protocols were excluded. Results: In 2011, 4,522 new male lung cancer cases were registered in the NHIF database, while we found 4,176 incident patients in 2016. The number of female patients increased from 2,636 to 2,828 during the same period. The mean age at diagnosis was 64.51 years for men (SD±9.85) and 64.93 years for women (SD±11.19) in 2011, increasing steadily to 65.80 years (SD±9.41) and 65.99 years (SD±10.45), respectively. Lung cancer incidence and mortality increases with age, peaking in the 70–79 age group (375.0/100,000 person-years) among males, while at 60–69 age group for females (148.1/100,000 person-years). The male-to-female incidence rate ratio reached 2.46 to 3.01 (p < 0.0001) among the 70–79 age group. We found 2-11% decrease in male incidence rate at most age groups, while a significant 1-3% increase was observed in older females ( > 60) annually during the study period. Conclusions: This nationwide epidemiology study demonstrated that LC incidence and mortality in Hungary is decreasing in younger male and female population, however we found significant increase of incidence in older female population, similar to international trends. Incidence rates peaked in younger age-groups compared to Western countries, most likely due to higher smoking prevalence in these cohorts, while lower age LC incidence could be attributed to higher competing cardiovascular risk resulting in earlier mortality in smoking population.

2021 ◽  
Vol 27 ◽  
Author(s):  
Lilla Tamási ◽  
Krisztián Horváth ◽  
Zoltán Kiss ◽  
Krisztina Bogos ◽  
Gyula Ostoros ◽  
...  

Objective: No assessment was conducted describing the age and gender specific epidemiology of lung cancer (LC) prior to 2018 in Hungary, thus the objective of this study was to appraise the detailed epidemiology of lung cancer (ICD-10 C34) in Hungary based on a retrospective analysis of the National Health Insurance Fund database.Methods: This longitudinal study included patients aged ≥20 years with LC diagnosis (ICD-10 C34) between January 1, 2011 and December 31, 2016. Patients with different cancer-related codes 6 months before or 12 months after LC diagnosis or having any cancer treatment other than lung cancer protocols were excluded.Results: Lung cancer incidence and mortality increased with age, peaking in the 70–79 age group (375.0/100,000 person-years) among males, while at 60–69 age group for females (148.1/100,000 person-years). The male-to-female incidence rate ratio reached 2.46–3.01 (p &lt; 0.0001) among the 70–79 age group. We found 2–11% decrease in male incidence rate at most age groups, while a significant 1–3% increase was observed in older females (&gt;60) annually during the study period.Conclusion: This nationwide epidemiology study demonstrated that LC incidence and mortality in Hungary decreased in younger male and female population, however we found significant increase of incidence in older female population, similar to international trends. Incidence rates peaked in younger age-groups compared to Western countries, most likely due to higher smoking prevalence in these cohorts, while lower age LC incidence could be attributed to higher competing cardiovascular risk resulting in earlier mortality in smoking population.


2020 ◽  
Author(s):  
Lilla Tamási ◽  
Krisztian Horvath ◽  
Zoltan Kiss ◽  
Krisztina Bogos ◽  
Gyula Ostoros ◽  
...  

Abstract Background: No assessment was conducted describing the age and gender specific epidemiology of lung cancer (LC) prior to 2018 in Hungary, thus the objective of this study was to appraise the detailed epidemiology of lung cancer (ICD-10 C34) in Hungary based on a retrospective analysis of the National Health Insurance Fund database.Methods: This longitudinal study included patients aged ≥20 years with LC diagnosis (ICD-10 C34) between 1th January 2011 and 31th December 2016. Patients with different cancer-related codes 6 months before or 12 months after LC diagnosis or having any anti-cancer treatment different from lung cancer protocols were excluded. Results: Lung cancer incidence and mortality increases with age, peaking in the 70–79 age group (375.0/100,000 person-years) among males, while at 60–69 age group for females (148.1/100,000 person-years). The male-to-female incidence rate ratio reached 2.46 to 3.01 (p<0.0001) among the 70–79 age group. We found 2-11% decrease in male incidence rate at most age groups, while a significant 1-3% increase was observed in older females (>60) annually during the study period.Conclusion: This nationwide epidemiology study demonstrated that LC incidence and mortality in Hungary is decreasing in younger male and female population, however we found significant increase of incidence in older female population, similar to international trends. Incidence rates peaked in younger age-groups compared to Western countries, most likely due to higher smoking prevalence in these cohorts, while lower age LC incidence could be attributed to higher competing cardiovascular risk resulting in earlier mortality in smoking population.


2004 ◽  
Vol 132 (1) ◽  
pp. 1-5 ◽  
Author(s):  
D. M. FLEMING ◽  
K. W. CROSS ◽  
W. A. COBB ◽  
R. S. CHAPMAN

We investigated age- and gender-specific incidence of shingles reported in a large sentinel practice network monitoring a defined population over the years 1994–2001. In total, 5915 male and 8617 female incident cases were studied. For each age group, we calculated the relative risk of females to males presenting with shingles. Incidence rates of chickenpox and herpes simplex were examined similarly. Shingles incidence was greater in females in each age group (except for 15–24 years). Relative risks (female to male) were greatest in age groups 45–64 years (1·48) and 0–14 years (1·43). There were no gender differences in the incidence of chickenpox except in the 15–24 years age group (female excess): for herpes simplex there were female excesses in all age groups. Gender-specific age-standardized incidence rates of shingles were calculated for each year and showed a consistent female excess in each of the 8 years (average annual excess 28%).


2003 ◽  
Vol 27 (1) ◽  
pp. 91-94 ◽  
Author(s):  
Ali Mentes ◽  
Julide Atukeren

The aim of the study was to evaluate toothbrushing management and ability of children in relation to age and gender. The study population consisted of 75 children and were divided into three equal groups as 3-5, 6-8 and 9-11 years of age.The grip type during toothbrushing was recorded on videotape.The most preferred grip types were distal (73%) followed by power (43%) and oblique grips (29%). There were a statistically significant differences between age groups and the grip types (p&lt;0.001) but no significant difference was seen between boys and girls in grip preferences (p&gt;0.05).The mean duration of toothbrushing was shorter in 3-5 years of age group (28 seconds) than the 6-8 and 9-11 age groups (35 and 47 seconds respectively).


2020 ◽  
Author(s):  
Peng Shi ◽  
Xiaobo Zhang ◽  
Lijuan Liu ◽  
Liangfeng Tang ◽  
Jing Li ◽  
...  

Abstract Background: Respiratory infections are one of three leading causes of childhood mortality, and worldwide increase and recent plateau in childhood asthma has been reported. However, data on trends of respiratory diseases over long period of time is limited. This study aimed to determine the trends of respiratory disease outpatient visits (ROVs) and diagnoses (RODs) in one of the largest children’s teaching hospitals in China between 2009 and 2018. Methods: A retrospective study based on routine administrative data was designed and implemented according to the RECORD statement. Demographic details and diagnoses of the outpatients <18 years visiting the respiratory department of the hospital were extracted from the Hospital Information System. Age- and gender-specific trends were illustrated by calculating average annual growth rate (AAGR) for ROVs and comparing change of proportion for different RODs over time. Results: There were 698054 ROVs from 285574 children (40.4% female). AAGR of ROVs was 15.2%. Children aged 4 to < 7 years had a faster increase than other age groups. Bronchitis (27.6%), pneumonia (18.5%), pneumonia affecting other systems (18.4%), asthma and status asthmaticus (10.7%), and vasomotor and allergic rhinitis (9.2%) accounted for 84.4% of all RODs. The proportion of bronchitis decreased across years, with the concomitant increasing trend in the proportion of pneumonia. Age-specific trend in diagnoses showed greater proportion of asthma in all visits for the children aged 7 to < 18 years than younger children. Gender-specific trend in diagnoses showed the proportion of asthma was greater for males but the AAGR was greater for females. Conclusion: The persistent upward trend in ROVs was observed among children at different ages and a gender difference was also seen. In contrast to what has been reported, burden of asthma and allergies diseases continues to increase locally.


2018 ◽  
Vol 3 (86) ◽  
Author(s):  
Lina Kreivėnaitė

Research background and hypothesis. Physical fitness problems in biathlon are quite extensively discussed, but biathlon shooting in Lithuania is not analyzed enough. The special literature lacks information about the shooting parameters that leaders demonstrate in the world biathlon championships. Moreover, shooting parameters in different age and gender groups have not been analyzed enough. The hypothesis that shooting parameters in adult, youth and junior age group biathletes would differ was tested. Research aim. The aim of our study was to analyze shooting parameters of biathletes in various age groups in 2011–2012 world championships and reveal fundamental differences in the aspects of age and gender. Research methods. Research participants were youths (age: 17–18 years), juniors (age: 19–20 years) and adults (age: 21–41 years), male and female biathletes. The number of subjects was 2175. Descriptive statistical methods were used for data analysis.Research results. Data analysis revealed the main differences in shooting parameters between adult, junior and youth groups, male and female biathletes. Also, comparison of shooting parameters between biathletes in various age groups and leaders in the same group was carried out. Discussion and conclusions. Our research revealed that the highest shooting accuracy was observed in adult male and female biathlete groups (p < 0.025). The shooting accuracy of junior and youth female biathletes was higher than that in the junior and youth male groups (p < 0.05). The longest average shooting time was in youth group (p < 0.001). The shooting time of biathletes in adult group was the shortest. We found that male biathletes in various age groups performed shots in less time compared to female biathletes (p < 0.05). Research results revealed that shooting parameters among leaders statistically significantly differed comparing them with the average shooting parameters in the group (p < 0.05).Keywords: biathlon, shooting accuracy, shooting time.


2017 ◽  
Vol 43 (6) ◽  
pp. 431-436 ◽  
Author(s):  
Juliana Pereira Franceschini ◽  
Sérgio Jamnik ◽  
Ilka Lopes Santoro

ABSTRACT Objective: To determine the demographic and clinical characteristics of patients with non-small cell lung cancer (NSCLC), as well as their disease course, by age group and gender. Methods: This was a retrospective cohort study of patients diagnosed with NSCLC from 2000 to 2012 and followed until July 2015 in a tertiary referral hospital in the city of São Paulo, Brazil. Based on the 25th and 75th percentiles of the age distribution, patients were stratified into three age groups: < 55 years; ≥ 55 and < 72 years; and ≥ 72 years. Survival time was evaluated during the follow-up period of the study. Functions of overall and gender-specific survival stratified by age groups (event: all-cause mortality) were calculated using the Kaplan-Meier method. Differences among survival curves were assessed via the log-rank test. Results: We included 790 patients with the following age distribution: < 55 years, 165 patients; ≥ 55 and < 72 years, 423; and ≥ 72 years, 202. In the entire sample, there were 493 men (62.4%). Adenocarcinoma was the most common histological pattern in the < 72-year age groups; 575 patients (73%) presented with advanced disease (stages IIIB-IV). The median 5-year survival was 12 months (95% CI: 4-46 months), with no significant differences among the age groups studied. Conclusions: NSCLC remains more common in men, although we found an increase in the proportion of the disease in women in the < 55-year age group. Adenocarcinoma predominated in women. In men, squamous cell carcinoma predominated in the ≥ 72-year age group. Most patients presented with advanced-stage disease at diagnosis. There were no statistical differences in survival between genders or among age groups.


2011 ◽  
Vol 8 (3) ◽  
pp. 352-360 ◽  
Author(s):  
Pedro Silva ◽  
Luisa Aires ◽  
Rute Marina Santos ◽  
Susana Vale ◽  
Greg Welk ◽  
...  

Background:The purpose of the study is to evaluate age and gender differences in objectively measured levels of physical activity (PA) in a large and diverse sample of residents from an urban area in Porto, Portugal.Methods:Participants included 822 residents, 334 males (41%), and 488 females (59%), aged 6 to 90 years. GT1M accelerometer was used to assess daily PA over 7 consecutive days, and the measurement was from October (2007) to June (2008).Results:Males were more active than females. This difference was attenuated in the 2 oldest age groups (40−59 and 60+ yrs). An accentuated declined in all PA variables occurred between the youngster group (6−11 yrs) and adolescents group (12−19 yrs). Surprisingly, young adults (20−39 yrs) engaged in more moderate-to-vigorous PA (MVPA) than adolescents. Further, females also had higher MVPA in the fourth group (40−59 yrs) compared with the second group (12−19 yrs). Males had higher compliance rates of PA guidelines than females regardless the age group considered. Adolescents had very low compliance rates (females = 18.18%; males = 33.50%).Conclusions:Porto metropolitan area residents had low rates of compliance with current PA guidelines. A low level of PA in Porto adolescents is a matter of concern and suggests that interventions are needed.


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
C Rammos ◽  
O Petrikhovich ◽  
A Mahabadi ◽  
M Steinmetz ◽  
J Lortz ◽  
...  

Abstract Background Cardiovascular diseases are the leading causes of death in the industrialized world. In addition to coronary heart disease, PAD defines morbidity and is associated with increased mortality. Guideline-recommended therapy and specialized ambulatory care is essential for optimal treatment. Knowledge of the treatment structures, contact with dedicated specialists and pharmacotherapy in the outpatient area are essential for improving treatment, reducing symptoms and finally improve mortality in this high-risk population. Methods The study is based on the ambulatory claims data of the panel doctors services according to § 295 SGB V and drug prescription data according to § 300 SGB V. The prevalence of PAD in Germany (medical diagnoses of PAD ICD I70.2–9) was analyzed by age and gender-specific characteristics with a timeframe of 10 years (2009–2018). In addition, the current ambulatory care structure was examined subdivided by vascular specialist (vascular surgeons or angiologists) and primary care physicians (internal medicine or general practitioners). Additionally, the prescription of guideline-recommended pharmacotherapy like statins and antiplatelet inhibitors was analyzed for the years 2009–2016. Results An increase of PAD diagnosis was observed with a maximum in 2018 with 2.280.000 patients in Germany. The rise of PAD patients strongly correlates with increased age (age group 50–59: 243.000, age group 60–69: 533.000, age group 70–79: 735.000, age group 75–79: 438.000, age group 80–89: 710.000) and more commonly affects males (55%) than females (45%). Access to vascular specialist was low for all age groups with only 11% of patients receiving care from vascular surgeons and only 9% from angiologists. However, 99% received care by a primary care physician. The prescription of lipid-lowering drugs and platelet aggregation inhibitors in the current analysis period from 2009–2016 is insufficient, with only 46% receiving statins and 29% receiving antiplatelets and 15% oral anticoagulation, Conclusion There are relevant differences in age and gender-specific prevalence of PAD in Germany. In addition to the regular care provided by primary care physicians, PAD patients are in need for specialized vascular care. Guideline recommended prescriptions are alarmingly low in PAD patients. There is a clear need to improve the treatment algorithms in the high-risk PAD population. Funding Acknowledgement Type of funding source: None


Retos ◽  
2015 ◽  
pp. 40-43
Author(s):  
Javier Yanci Irigoyen ◽  
Asier Los Arcos

El principal objetivo de esta investigación fue conocer la influencia de la edad y el género en la capacidad de cambiar de dirección (CODA) en niños y niñas de educación primaria. En este estudio participaron 343 niños y niñas (8.2 ± 1.1 años, 143.2 ± 8.7 cm, 37.8 ± 9.9 kg) estudiantes de primer, segundo, tercer y cuarto curso de educación primaria. Para evaluar la CODA se utilizó el Modified Agility Test (MAT). Los resultados mostraron diferencias significativas (F(3) = 56.25, p ≤ 0.001) entre los grupos de edad. Las diferencias en la CODA entre chicos y chicas no se han manifestado hasta el cuarto curso (t(56) = -2.30, p = 0.02) de educación primaria. Atendiendo a la edad y al género, la evolución de los chicos y las chicas fue diferente. Estos resultados pueden exponer la necesidad de implementar programas específicos para mejorar la capacidad de cambio de dirección en distintos momentos en función de la edad y del género.Abstract. The main objective of this study was to determine the influence of age and gender on the ability to change direction (ACD) in elementary education children. This study involved 343 children (8.2 ± 1.1 years, 143.2 ± 8.7 cm, 37.8 ± 9.9 kg) from first, second, third and fourth year of elementary education. The Modified Agility Test (MAT) was used to evaluate the ACD. The results showed significant differences (F(3) = 56.25, p ≤ 0.001) between the age groups. Differences in ACD between boys and girls have not manifested through fourth grade (t(56) = -2.30, p = 0.02). The development of boys and girls was different by age. These results may lead us to think about the need to implement age- and gender-specific programs to improve the ACD at different times.


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