scholarly journals Determinants of Early Cancer Screening Behaviour in Nigeria

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 54s-54s
Author(s):  
R.C.W. Chidebe ◽  
T.C. Orjiako ◽  
D.K. Atakere ◽  
O.O. Arowosegbe ◽  
D. Onu ◽  
...  

Background: Early detection and improvements/advancements in medicine have contributed to an overall decrease in mortality and morbidity rates resulting from cancer diagnoses. Despite this improvement in national and global health status, Nigerians continue to be diagnosed at a later stage, with a more aggressive disease state. This is an important observation given the impact cancer has on the abilities of individuals to function physically, psychologically, and socially within the context of their environment. It is important therefore to identify and target specific groups that may be less willing to present for early cancer screening. Aim: To understand the characteristics of people who are likely or not likely to present for early cancer screening among Nigerians, and to address the use of mechanisms by which to ensure a timely diagnosis of preventable cancers among Nigerians. Methods: Adult Nigerians (N=144), 18-71 years of age who presented for clinical breast exam (CBE), visual inspection with acetic acid (VIA) and prostate specific antigen test (PSA) screenings after an awareness exercise; completed survey forms which included a personality inventory, early cancer detection behavior scale and a demography profile. Multiple regression and ANOVA were used to examine predictive patterns as well as differences between and within groups. Results: Results showed income ( b = 0.18, P < .05) to be a significant determinant of early cancer detection behavior, such that higher income earners were more likely to go for screening. There were also significant gender differences in current cancer detection behavior between males (M = 0.15, SD = 0.51) and females (M= 0.47, SD = 0.80); males are less likely to engage in early detection behavior ( F(1,145) = 4.76, P = .03). Data further show differences between older (≥ 41) and younger (≤ 40) participants in intention to screen for cancer, with older participants reporting more willingness to engage in cancer screening. Conclusion: Our finding enhances our understanding of the profile of the groups who are less likely to screen for cancer. Also, it suggests that awareness campaign and free screening exercises should target these at-risk groups in Nigeria.

2018 ◽  
Vol 4 (Supplement 3) ◽  
pp. 33s-33s
Author(s):  
Tochukwu Charles Orjiako

Purpose Early detection and improvements and advancements in medicine have contributed to an overall decrease in mortality and morbidity rates that result from cancer diagnoses. Despite this improvement in national and global health status, Nigerians continue to be diagnosed at a later stage and with a more aggressive disease state. This is an important observation given the impact that cancer has on the ability of individuals to function physically, psychologically, and socially within the context of their environment. It is important, therefore, to identify and target specific groups that may be less willing to present for early cancer screening. The aim of this work was to understand the characteristics of Nigerians who are likely or not to present for early cancer screening and to address the use of mechanisms by which we can ensure the timely diagnosis of preventable cancers among Nigerians. Methods Adult Nigerians (N = 144), age 18 to 71 years, presented for clinical breast examination, visual inspection with acetic acid, and prostate-specific antigen test screenings after an awareness exercise. Participants completed survey forms that included a personality inventory, early cancer detection behavior scale, and a demography profile. We used multiple regression and analysis of variance to examine predictive patterns and differences between and within groups. Results Our results indicate that income (β = .18; P < .05) is a significant determinant of early cancer detection behavior, such that higher earners were more likely to go for screening. There were also significant gender differences in current cancer detection behavior between males (mean, 0.15; standard deviation, 0.51) and females (mean, 0.47; standard deviation, 0.80). Males are less likely to engage in early detection behavior (F1,145 = 4.76; P = .03). Data also show differences between older (age > 41 years) and younger (age < 40 years) participants in the intention to screen for cancer, with older participants reporting more willingness to engage in cancer screening. Conclusion Our findings enhance our understanding of the profile of groups who are less likely to screen for cancer. Our results also suggest that awareness campaigns and free screening exercises should target these at-risk groups in Nigeria. AUTHOR’S DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated. Relationships are self-held unless noted. I = Immediate Family Member, Inst = My Institution. Relationships may not relate to the subject matter of this manuscript. For more information about ASCO's conflict of interest policy, please refer to www.asco.org/rwc or ascopubs.org/jco/site/ifc . No COIs from the author.


2018 ◽  
Vol 4 (Supplement 3) ◽  
pp. 26s-26s
Author(s):  
Carlos Munoz-Zuluaga ◽  
Armando Sardi ◽  
Mavalynne Orozco-Urdaneta ◽  
Luis Gabriel Parra-Lara ◽  
Andres Perez ◽  
...  

Purpose For Colombian women, breast and cervical cancer are the leading causes of mortality, despite being potentially curable through early detection and timely treatment. Tedious administrative processes and a lack of cancer screening education and awareness hinders early detection. Mobile applications (mApps) have permeated all levels of society and are potential tools by which to deliver personalized information and identify high-risk patients in need of screening tests thereby improving early cancer detection. The aim of this work is to create a free mApp that educates and guides patients to the national screening programs for breast and cervical cancer. Methods An mApp Amate was advertised to women (age ≥ 14 years) in the waiting rooms of a health care facility of a community hospital during a period of 9 months. Amate used educational, evaluative, and risk factor questions to measure the population’s knowledge of breast and cervical cancer. Each question was followed by an explanation. Correct answers yielded points that were redeemable for cellular data. Risk assessment questions identified women who required screening who were subsequently contacted by a health care provider and enrolled in the national cancer care program. Results A total of 4,553 women were contacted from August 2017 to May 2018. Of this group, 830 downloaded Amate and answered all of the questions. On the basis of the risk factor questions, 16% of patients (n = 131) were identified as being at risk for breast and/or cervical cancer and needed to be enrolled in the national screening program. Thus far, 24% of patients (n = 32) have successfully completed their recommended screening tests—mammogram, Papanicolau smear, or both. We also identified specific barriers to enrolling patients in these programs, including an unwillingness to be enrolled, limited available appointments at health care centers, and denied access as a result of health care coverage. Conclusion Amate is a low-cost, accessible tool that identifies women who are at risk for breast and cervical cancer and detects access barriers to early cancer detection. Administrative obstacles still exist and must be addressed to improve early cancer detection and screening. Amate has the potential to reach people from rural areas of Colombia and other underserved countries. AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated. Relationships are self-held unless noted. I = Immediate Family Member, Inst = My Institution. Relationships may not relate to the subject matter of this manuscript. For more information about ASCO's conflict of interest policy, please refer to www.asco.org/rwc or ascopubs.org/jco/site/ifc . Armando Sardi Stock or Other Ownership: Celgene, Johnson & Johnson Mavalynne Orozco-Urdaneta Employment: Partners For Cancer Care And Prevention Foundation, Stamina-in-Action Stock or Other Ownership: Celgene, Johnson & Johnson Luis Gabriel Parra-Lara Research Funding: Merk & Co


Cancer ◽  
1972 ◽  
Vol 30 (3) ◽  
pp. 774-781 ◽  
Author(s):  
Henry T. Lynch ◽  
William Harlan ◽  
Milton Swartz ◽  
John Marley ◽  
William Becker ◽  
...  

Author(s):  
Minetta C. Liu

SummaryEarly cancer detection should lead to an overall stage shift, less-intensive treatments and better patient outcomes. Current recommended screening programmes are limited to a handful of individual cancers. A multi-cancer early detection test that simultaneously detects and localises multiple cancers could reduce the morbidity and mortality associated with cancer.


1988 ◽  
Vol 78 (1) ◽  
pp. 58-60 ◽  
Author(s):  
S A Grover ◽  
E F Cook ◽  
L Goldman

2002 ◽  
Vol 18 (4) ◽  
pp. 153-158 ◽  
Author(s):  
Steven J. Zullo ◽  
Sudhir Srivastava ◽  
J. Patrick Looney ◽  
Peter E. Barker

A recent meeting jointly sponsored by the National Cancer Institute (NCI) and National Institute of Standards and Technology (NIST) brought together researchers active in nanotechnology and cancer molecular biology to discuss and evaluate the interface between disciplines. Emerging areas where nanotechnologies may impact cancer prevention and early cancer detection were elaborated by key researchers who catalyzed interdisciplinary dialogue aimed at fostering cross-discipline communications and future collaboration.


2020 ◽  
Vol 38 (15_suppl) ◽  
pp. 2065-2065
Author(s):  
Carlos A. Munoz-Zuluaga ◽  
José David Gallo-Perez ◽  
Andres Perez-Bustos ◽  
Mavalynne Orozco-Urdaneta ◽  
Karen Druffel ◽  
...  

2065 Background: Despite being potentially curable with early detection and timely treatment, breast (BC) and cervical cancers (CC) remain leading causes of death for Colombian women. Lack of cancer screening education, tedious administrative processes, and geographical limitations hinder early cancer detection. Today, technological tools permeate all levels of society and could gather data for user risk stratification, deliver clear and customized information, and help with care coordination, tracking, and addressing communication, transportation, and financial barriers. We aimed to assess the effectiveness of a free mobile application (mApp) to reach women, understand misconceptions about cancer screening, identify users at risk for BC and CC, and coordinate screening tests in Cali, Colombia. Methods: The mApp, Ámate, was developed over 4 months and advertised to women (≥14 years) in waiting rooms of 4 healthcare facilities in Cali, Colombia for 23 months. Ámate used educational, evaluative, and risk factor questions followed by brief explanations to assess the population’s knowledge, educate users on BC and CC, and identify users in need of BC and/or CC screenings. Correct answers yielded points redeemable for cellular data. Women who required screening were subsequently navigated to a healthcare provider and enrolled in the national cancer program. Results: From August 2017-August 2019, 1,043 women from Cali downloaded Ámate and answered all questions. Misconceptions about BC included beliefs that BC can be prevented (87%), obesity does not increase the risk of BC (49%), deodorant causes BC (17%), and only women with a relative with BC can get BC (16%). For CC, misconceptions included that pap smears should not be performed while sexually active (64%), vaginal pain is an early sign of CC (44%), and only women contract HPV (33%). Overall, 31.5% (329) were identified as at-risk and needed a mammogram and/or pap smear. So far, 30% (98) were successfully navigated and completed their recommended screening test(s). Barriers to enrollment in these programs included patient unwillingness, using fake contact information, limited available appointments, and denied access due to healthcare coverage. Conclusions: Ámate is an accessible tool that identifies women at-risk for breast and cervical cancer and detects barriers to early cancer detection. Administrative obstacles exist and must be addressed to improve early cancer detection/screening. Ámate is currently being tested in other areas of Colombia and may be useful in other underserved countries.


JAMA ◽  
2020 ◽  
Vol 323 (23) ◽  
pp. 2429
Author(s):  
Héloïse Schmeltz ◽  
Cédric Rat ◽  
Corinne Pogu ◽  
Gaëlle Bianco ◽  
Anne Cowppli-Bony ◽  
...  

2021 ◽  
Vol 67 (5) ◽  
pp. 593-599
Author(s):  
Grigoriy Yanus ◽  
Tatiana Laidus ◽  
Aleksandr S Martianov ◽  
Svetlana Aleksakhina ◽  
Ekaterina Kuligina ◽  
...  

Until recently, the establishment of a universal test, allowing the early cancer detection by the analysis of blood, urine or other biological fluids seemed as realistic as the development of "Perpetuum mobile". There are numerous obstacles on this road: above all being the ultra-low concentrations of biomarkers shed by such tumors in the bloodstream. Meanwhile, in attempts to create such a test, the methodology of ultrasensitive DNA analysis has emerged, and stunning practical successes have been achieved in this field over the past few years. The performance of the CancerSEEK test has already reached the threshold for clinical utility of its practical implementation. Techniques based on the analysis of methylation patterns (Galleri test, cfMeDIP-seq) are also rapidly developing. A number of promising studies are based on quite unconventional approaches, for example, the analysis of tumor-associated viral or microbial DNA sequences circulating in plasma. In addition to universal tests aiming at the detection of any or many types of neoplasms in older people, the methods for early DNA-based detection of certain cancer types in selected high-risk groups are being developed. These advances finally make the prospects for introducing liquid biopsy into routine cancer screening look like a matter of the near future.


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