Potential Brain Health Benefits of Royal Jelly

Abstract The worlds’ population is aging leading to increased rates of neurodegenerative disorders. Exercise has countless health benefits and has consistently been shown to improve brain health and cognitive function. The purpose of this review is to provide an overview of exercise-induced adaptations in the brain with a focus on crosstalk between peripheral tissues and the brain. We highlight recent studies into exercise-induced circulating factors, or exerkines, including irisin, cathepsin B, GPLD1, ketones, and the mechanisms mediating their effects in the brain.

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Bioactive Constituents in Indian Medicinal Plants Traditionally Recognized for Brain Health Benefits

Antioxidants and Functional Foods for Neurodegenerative Disorders ◽

10.1201/9780429319310-22 ◽

2020 ◽

pp. 277-327

Author(s):

Deepak Mundkinajeddu ◽

Amit Agarwal ◽

Gururaja Giligar Manjunatha ◽

Vineet Kumar Singh

Keyword(s):

Medicinal Plants ◽

Health Benefits ◽

Brain Health ◽

Bioactive Constituents ◽

Indian Medicinal Plants

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Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits

Oxidative Medicine and Cellular Longevity ◽

10.1155/2017/1259510 ◽

2017 ◽

Vol 2017 ◽

pp. 1-21 ◽

Cited By ~ 120

Author(s):

Visweswara Rao Pasupuleti ◽

Lakhsmi Sammugam ◽

Nagesvari Ramesh ◽

Siew Hua Gan

Keyword(s):

Wound Healing ◽

Neurodegenerative Disorders ◽

Royal Jelly ◽

Metabolic Diseases ◽

Health Benefits ◽

Mechanisms Of Action ◽

Gastrointestinal Disorders ◽

Protective Effects ◽

Potential Health ◽

Microbial Inhibition

Background. There are several health benefits that honeybee products such as honey, propolis, and royal jelly claim toward various types of diseases in addition to being food. Scope and Approach. In this paper, the effects of honey, propolis, and royal jelly on different metabolic diseases, cancers, and other diseases have been reviewed. The modes of actions of these products have also been illustrated for purposes of better understanding. Key Findings and Conclusions. An overview of honey, propolis, and royal jelly and their biological potentials was highlighted. The potential health benefits of honey, such as microbial inhibition, wound healing, and its effects on other diseases, are described. Propolis has been reported to have various health benefits related to gastrointestinal disorders, allergies, and gynecological, oral, and dermatological problems. Royal jelly is well known for its protective effects on reproductive health, neurodegenerative disorders, wound healing, and aging. Nevertheless, the exact mechanisms of action of honey, propolis, and royal jelly on the abovementioned diseases and activities have not been not fully elucidated, and further research is warranted to explain their exact contributions.

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Current Evidence on the Effect of Dietary Polyphenols Intake on Brain Health

Current Nutrition & Food Science ◽

10.2174/1573401316999200714160126 ◽

2020 ◽

Vol 16 (8) ◽

pp. 1170-1182 ◽

Cited By ~ 3

Author(s):

Stefania D'Angelo

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Dietary Intake ◽

Neurodegenerative Diseases ◽

Health Benefits ◽

Current Evidence ◽

Brain Health ◽

Dietary Polyphenols ◽

The Central Nervous System ◽

The Brain

Background: In recent years, the possibility of favorably influencing the cognitive capacity through the promotion of lifestyle modifications has been increasingly investigated. In particular, the relationship between nutritional habits and brain health has attracted special attention. Polyphenols are secondary metabolites of plants. These phytochemicals are present in vegetables, fruits, legumes, olive oil, nuts. They include several antioxidant compounds and are generally considered to be involved in defense against chronic human diseases. In recent years, there has been a growing scientific interest in their potential health benefits to the brain. Objective: In this mini-review, we focus on the current evidence defining the position of polyphenols dietary intake in the prevention/slowdown of human neurodegenerative diseases. Methods: A literature research was performed using the keywords “polyphenols”, “brain”, “nutrition”, individually or all together, focusing on human trials. Results: The available clinical studies on the effect of polyphenols on cognitive functions are quite convincing. Regular dietary intake of polyphenols would seem to reduce the risk of neurodegenerative diseases. Moreover, beyond their beneficial power on the central nervous system, these phytochemicals seem also to be able to work on numerous cellular targets. They show different biological actions, that however, have to be confirmed in long-term randomized clinical trials. Currently, most data propose that a combination of phytonutrients instead of any single polyphenol is responsible for health benefits. Conclusions: Evolving indications suggest that dietary polyphenols may exercise beneficial actions on the central nervous system, thus representing a possible tool to preserve cognitive performance. Key questions to improve the coherence and reproducibility in the development of polyphenols as a possible future therapeutic drug require a better understanding of the sources of polyphenols, their treatment and more standardized tests including bioavailability of bioactive metabolites and studies of permeability of the brain.

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Selenium-rich royal jelly inhibits hepatocellular carcinoma through PI3K/AKT and VEGF pathways in H22 tumor-bearing mice

Food & Function ◽

10.1039/d1fo01070k ◽

2021 ◽

Author(s):

Xuepeng Chi ◽

Zhenguo Liu ◽

Wei Wei ◽

Xiyi Hu ◽

Ying Wang ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Royal Jelly ◽

Health Benefits ◽

Tumor Bearing

Royal jelly (RJ) and selenium (Se)-rich foods have well-known health benefits that are attributable to a broad range of pharmacologic effects including antioxidant, anti-tumor, and immunoregulatory activities. However, the physiologic...

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