Nanocoutured Metallic Biomaterials and Surface Functionalization of Titanium-Based Alloys for Medical Applications

2018 ◽  
pp. 17-50
Author(s):  
Jalal Azadmanjiri ◽  
Wai Hong Wong ◽  
Jagat R. Kanwar ◽  
Christopher C. Berndt ◽  
James Wang ◽  
...  
Keyword(s):  
Surface Functionalization ◽  
Medical Applications ◽  
Metallic Biomaterials

scholarly journals Surface Modifications of Biodegradable Metallic Foams for Medical Applications

Coatings ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 819
Author(s):  
Renáta Oriňaková ◽  
Radka Gorejová ◽  
Zuzana Orságová Králová ◽  
Andrej Oriňak
Keyword(s):  
Bone Tissue ◽  
Surface Modifications ◽  
Metallic Foam ◽  
Future Research ◽  
Medical Applications ◽  
Metallic Foams ◽  
Preparation Methods ◽  
Processing Technologies ◽  
Metallic Biomaterials ◽  
Bonding Properties

Significant progress was achieved presently in the development of metallic foam-like materials improved by biocompatible coatings. Material properties of the iron, magnesium, zinc, and their alloys are promising for their uses in medical applications, especially for orthopedic and bone tissue purposes. Current processing technologies and a variety of modifications of the surface and composition facilitate the design of adjusted medical devices with desirable mechanical, morphological, and functional properties. This article reviews the recent progress in the design of advanced degradable metallic biomaterials perfected by different coatings: polymer, inorganic ceramic, and metallic. Appropriate coating of metallic foams could improve the biocompatibility, osteogenesis, and bone tissue-bonding properties. In this paper, a comprehensive review of different coating types used for the enhancement of one or several properties of biodegradable porous implants is given. An outline of the conventional preparation methods of metallic foams and a brief overview of different alloys for medical applications are also provided. In addition, current challenges and future research directions of processing and surface modifications of biodegradable metallic foams for medical applications are suggested.

Surface Functionalization and Antibacterial Characteristics of the Titanium-Based Metallic Biomaterials at Nanoscale

2018 ◽  
pp. 167-194
Author(s):  
Jalal Azadmanjiri ◽  
Wai Hong Wong ◽  
Jagat R. Kanwar ◽  
Christopher C. Berndt ◽  
James Wang ◽  
...  
Keyword(s):  
Surface Functionalization ◽  
Metallic Biomaterials

Advanced carbon dots via plasma-induced surface functionalization for fluorescent and bio-medical applications

Nanoscale ◽  
2017 ◽  
Vol 9 (26) ◽  
pp. 9210-9217 ◽  
Author(s):  
So Young Park ◽  
Che Yoon Lee ◽  
Ha-Rim An ◽  
Hyeran Kim ◽  
Young-Chul Lee ◽  
...  
Keyword(s):  
Surface Functionalization ◽  
Carbon Dots ◽  
Medical Applications

scholarly journals Biocompatible Titanium Alloys used in Medical Applications

2019 ◽  
Vol 70 (4) ◽  
pp. 1302-1306 ◽  
Author(s):  
Madalina Simona Baltatu ◽  
Catalin Andrei Tugui ◽  
Manuela Cristina Perju ◽  
Marcelin Benchea ◽  
Mihaela Claudia Spataru ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Corrosion Resistance ◽  
Biomedical Applications ◽  
Elasticity Modulus ◽  
Medical Applications ◽  
Global Level ◽  
Medical Field ◽  
High Corrosion Resistance ◽  
Metallic Biomaterials ◽  
Ti Alloys

At global level, there is a continuing concern for the research and development of alloys for medical and biomedical applications. Metallic biomaterials are used in various applications of the most important medical fields like orthopedic, dental and cardiovascular. The main metallic biomaterials used in human body are stainless steels, Co-based alloys and Ti-based alloys. Titanium and its alloys are of greater interest in medical applications because they exhibit characteristics required for implant materials, namely, good mechanical properties (less elasticity modulus than stainless steel or CoCr alloys, fatigue strength, high corrosion resistance), high biocompatibility. The aim of this review is to describe and compare the main characteristics (mechanical properties, corrosion resistance and biocompatibility) for latest research of nontoxic Ti alloys biomaterials used for medical field.

Advanced Metallic Biomaterials

2022 ◽  
Author(s):  
Madalina-Simona Baltatu
Keyword(s):  
Stainless Steels ◽  
Medical Applications ◽  
Metallic Biomaterials

The book presents the characterization and classification of metallic biomaterials; with focus on titanium-based alloys, cobalt-based alloys, stainless steels and biodegradable alloys. Emphasis is placed on the synthesis, assessment of properties and medical applications such as multifunctional implants. The book references 423 original resources and includes their direct web link for in-depth reading.

scholarly journals Polymer-Based Electrophoretic Deposition of Nonwovens for Medical Applications: The Effect of Carrier Structure, Solution, and Process Parameters

Marine Drugs ◽  
2021 ◽  
Vol 19 (10) ◽  
pp. 533
Author(s):  
Ewelina Pabjanczyk-Wlazlo ◽  
Nina Tarzynska ◽  
Anna Bednarowicz ◽  
Adam Puszkarz ◽  
Grzegorz Szparaga
Keyword(s):  
Process Parameters ◽  
Electrophoretic Deposition ◽  
Structural Characteristics ◽  
Complex Structure ◽  
Poly Lactic Acid ◽  
Medical Applications ◽  
Fibrous Materials ◽  
Surface Mass ◽  
Metallic Biomaterials ◽  
Molecular Structure Analysis

Hyaluronate and alginate are non-toxic and biocompatible polymers, which can be used for surface modification and functionalization of many kinds of materials. Electrophoretic deposition (EPD) has several advantages, including its versatility, simplicity, and ability to coat substrates with complex shapes, and is used for the creation of antimicrobial or hydrophobic coatings on metallic biomaterials, among other applications. However, its utilization for applying biopolymer layers on textiles is very limited due to the more complex structure and spatial characteristics of fibrous materials. The aim of this research was to analyze the effects of selected EPD process parameters and the structural characteristics of fibrous carriers on the kinetics of the process and the microscopic characteristics of the deposited layers. The influence of solution characteristics, process parameters, and carrier structures obtained using two different techniques (melt blown and spun-bonded) were analyzed. The morphology and structure of the created deposits were analyzed using scanning electron microscopy and computed tomography, and molecular structure analysis was performed with Fourier Transform Infrared spectroscopy. The surface mass and thickness of fibrous poly (lactic acid)-based carriers were analyzed in accordance with the respective standards. This study serves as a basis for discussion and further development of this method with regard to fibrous materials for medical applications.

Bioinspired surface functionalization of metallic biomaterials

2018 ◽  
Vol 77 ◽  
pp. 90-105 ◽  
Author(s):  
Yingchao Su ◽  
Cheng Luo ◽  
Zhihui Zhang ◽  
Hendra Hermawan ◽  
Donghui Zhu ◽  
...  
Keyword(s):  
Surface Functionalization ◽  
Metallic Biomaterials

Fabrication and Characterization of Metallic Biomaterials in Medical Applications

2021 ◽  
pp. 95-105
Author(s):  
Ganesh Kumar Sharma ◽  
Vikas Kukshal ◽  
Deepika Shekhawat ◽  
Amar Patnaik
Keyword(s):  
Medical Applications ◽  
Metallic Biomaterials ◽  
Fabrication And Characterization

Porous Metallic Biomaterials Processing (Review) Part 1: Compaction, Sintering Behavior, Properties and Medical Applications

2017 ◽  
Vol 15 (13) ◽  
pp. 28-40
Author(s):  
Ileana Nicoleta Popescu ◽  
Ruxandra Vidu ◽  
Vasile Bratu
Keyword(s):  
Sintering Behavior ◽  
Medical Applications ◽  
Biomedical Domain ◽  
Metallic Materials ◽  
Medical Implants ◽  
Metallic Biomaterials ◽  
Controlled Porosity ◽  
Complex Forms ◽  
Materials Used ◽  
Porous Biomaterials

AbstractOver the last few decades, researchers has been focused on the study of processing using different methods of new biocompatible and/or biodegradable materials such as permanent or temporary medical implants in reconstructive surgery. The advantages of obtaining biomedical implants by Powder Metallurgy (P/M) techniques are (i) obtaining the near-net-shaped with complex forms, (ii) making materials with controlled porosity or (iii) making mechanically resistant sintered metallic materials used as reinforcing elements for ceramic/polymeric biocompatible materials. In this first part of the 2-part review, the most used and newest metallic biomaterials obtained by P/M methods are presented, along with their compaction and sintering behavior and the properties of the porous biomaterials studied in correlation with the biomedical domain of application.

scholarly journals Bioorthogonal Functionalization of Material Surfaces with Bioactive Molecules

2021 ◽  
Author(s):  
Kern Hast ◽  
Zhaoju Jia ◽  
Melih Baci ◽  
Tushar Aggarwal ◽  
Enver C Izgu
Keyword(s):  
Cell Adhesion ◽  
Surface Functionalization ◽  
Medical Devices ◽  
Cyclic Peptide ◽  
Bioactive Molecules ◽  
Metal Catalyst ◽  
Medical Applications ◽  
Biological Applications ◽  
Cytoskeletal Organization ◽  
Material Surfaces

The ability to control and modify the bioactivity of surfaces is pivotal to the success of many medical devices. A biocompatible and bioorthogonal method to functionalize surfaces with a wide variety of bioactive molecules is an important tool for enabling innovative biotechnology and medical applications. We report herein a novel, catecholamine-based surface functionalization method that is chemoselective and free of a metal catalyst. This method utilizes the ligation between a coating formed from the tyrosinase-catalyzed polymerization of a tetrazine-containing catecholamine and one or more strained alkene-containing molecules of interest. The process is achieved under conditions ideal for biological applications. Using this method, we graft surfaces with a variety of active molecules, including a small molecule fluorophore, enzymes, and a cyclic peptide with the RGD motif, and demonstrate the maintenance of their activity on the surface. Additionally, we establish the cytocompatibility of grafted ECM-mimicking surfaces with fibroblasts and show improved cell adhesion and cytoskeletal organization.

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