Nationwide Trends in Incidence and Mortality of Stroke Among Younger and Older Adults in Denmark

ObjectiveTo investigate the extent to which the incidence and mortality of a first-time stroke among younger and older adults changed from 2005 to 2018 in Denmark using nationwide registries.MethodsWe used the Danish Stroke Registry and the Danish National Patient Registry to identify patients 18 to 49 years of age (younger adults) and those ≥50 years of age (older adults) with a first-time ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage. We computed age-standardized incidence rates and 30-day and 1-year mortality risks separately for younger and older adults and according to smaller age groups, stroke subtype, sex, and severity (Scandinavian Stroke Scale score). Average annual percentage changes (AAPCs) were computed to assess temporal trends.ResultsWe identified 8,680 younger adults and 105,240 older adults with an ischemic stroke or intracerebral hemorrhage. The incidence rate per 100,000 person-years of ischemic stroke (20.8 in 2005 and 21.9 in 2018, AAPC −0.6 [95% confidence interval (CI) −1.5 to 0.3]) and intracerebral hemorrhage (2.2 in 2005 and 2.5 in 2018, AAPC 0.6 [95% CI −1.0 to 2.3]) remained steady in younger adults. In older adults, rates of ischemic stroke and intracerebral hemorrhage declined, particularly in those ≥70 years of age. Rates of subarachnoid hemorrhage declined, but more so in younger than older adults. Stroke mortality declined over time in both age groups, attributable largely to declines in the mortality after severe strokes. Most trends were similar for men and women.ConclusionThe incidence of ischemic stroke and intracerebral hemorrhage was steady in younger adults from 2005 to 2018, while it dropped in adults >70 years of age. Stroke mortality declined during this time.

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Trends in age- and sex-specific prevalence and incidence of cardiovascular disease in Western Australia

European Journal of Preventive Cardiology ◽

10.1177/2047487318786585 ◽

2018 ◽

Vol 25 (12) ◽

pp. 1280-1290 ◽

Cited By ~ 11

Author(s):

Danja Sarink ◽

Lee Nedkoff ◽

Tom Briffa ◽

Jonathan E Shaw ◽

Dianna J Magliano ◽

...

Keyword(s):

Cardiovascular Disease ◽

Older Adults ◽

Temporal Trends ◽

Incidence Rates ◽

Younger Adults ◽

Important Indicator ◽

Annual Prevalence ◽

Incidence And Mortality ◽

Western Australian ◽

Age And Sex

Background Temporal trends in incidence and mortality of cardiovascular disease (CVD) have been well described, with recent data suggesting declining improvements in those aged under 55 years. However, little is known about the combined impact of incidence and mortality trends on disease prevalence, an important indicator of disease burden and cost. We analysed changes in age-specific and age-standardised temporal trends in prevalence and incidence of CVD subtypes. Methods Annual prevalence and incidence rates of coronary heart disease, cerebrovascular disease and peripheral arterial disease for the Western Australian population for 1995–2010 were calculated using data from the Western Australian Data Linkage System. Joinpoint regression analyses were used to identify joinpoints in trends in age-specific and age-standardised annual prevalence and incidence rates for each CVD subtype. Results Between 1995 and 2010, age- and sex-specific incidence and prevalence of the CVD subtypes generally decreased among middle-aged and older adults, but were stable or increased among younger adults. In < 55 year olds, increases in incidence tended to occur from 2003, while increases in prevalence were from 2007/2008. Declines in age-standardised incidence were greater than those in crude incidence, with changes in population structure having a greater impact among men than women. Conclusions The majority of CVDs occurs in older adults. Our findings of generally worsening trends in prevalence in younger adults across most CVD subtypes were in contrast to generally declining trends in older age groups. These data highlight the importance of monitoring prevalence and incidence, particularly in younger adults.

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Cognitive Load Affects Speech Motor Performance Differently in Older and Younger Adults

Journal of Speech Language and Hearing Research ◽

10.1044/2018_jslhr-s-17-0222 ◽

2019 ◽

Vol 62 (5) ◽

pp. 1258-1277 ◽

Cited By ~ 1

Author(s):

Megan K. MacPherson

Keyword(s):

Older Adults ◽

Cognitive Load ◽

Motor Performance ◽

Age Groups ◽

Incongruent Condition ◽

Sentence Production ◽

Movement Duration ◽

Production Task ◽

Younger Adults ◽

Speech Motor

PurposeThe aim of this study was to determine the impact of cognitive load imposed by a speech production task on the speech motor performance of healthy older and younger adults. Response inhibition, selective attention, and working memory were the primary cognitive processes of interest.MethodTwelve healthy older and 12 healthy younger adults produced multiple repetitions of 4 sentences containing an embedded Stroop task in 2 cognitive load conditions: congruent and incongruent. The incongruent condition, which required participants to suppress orthographic information to say the font colors in which color words were written, represented an increase in cognitive load relative to the congruent condition in which word text and font color matched. Kinematic measures of articulatory coordination variability and movement duration as well as a behavioral measure of sentence production accuracy were compared between groups and conditions and across 3 sentence segments (pre-, during-, and post-Stroop).ResultsIncreased cognitive load in the incongruent condition was associated with increased articulatory coordination variability and movement duration, compared to the congruent Stroop condition, for both age groups. Overall, the effect of increased cognitive load was greater for older adults than younger adults and was greatest in the portion of the sentence in which cognitive load was manipulated (during-Stroop), followed by the pre-Stroop segment. Sentence production accuracy was reduced for older adults in the incongruent condition.ConclusionsIncreased cognitive load involving response inhibition, selective attention, and working memory processes within a speech production task disrupted both the stability and timing with which speech was produced by both age groups. Older adults' speech motor performance may have been more affected due to age-related changes in cognitive and motoric functions that result in altered motor cognition.

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Video Games and Emotion Regulation

GeroPsych ◽

10.1024/1662-9647/a000196 ◽

2018 ◽

Vol 31 (4) ◽

pp. 205-213 ◽

Cited By ~ 1

Author(s):

Kathryn L. Ossenfort ◽

Derek M. Isaacowitz

Keyword(s):

Older Adults ◽

Emotion Regulation ◽

Video Games ◽

Age Differences ◽

Interactive Media ◽

Age Groups ◽

Younger Adults ◽

Media Usage ◽

The Everyday ◽

Media Preferences

Abstract. Research on age differences in media usage has shown that older adults are more likely than younger adults to select positive emotional content. Research on emotional aging has examined whether older adults also seek out positivity in the everyday situations they choose, resulting so far in mixed results. We investigated the emotional choices of different age groups using video games as a more interactive type of affect-laden stimuli. Participants made multiple selections from a group of positive and negative games. Results showed that older adults selected the more positive games, but also reported feeling worse after playing them. Results supplement the literature on positivity in situation selection as well as on older adults’ interactive media preferences.

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Are the Acute Effects of THC Different in Aging Adults?

Brain Sciences ◽

10.3390/brainsci11050590 ◽

2021 ◽

Vol 11 (5) ◽

pp. 590

Author(s):

Raeghan L. Mueller ◽

Jarrod M. Ellingson ◽

L. Cinnamon Bidwell ◽

Angela D. Bryan ◽

Kent E. Hutchison

Keyword(s):

Older Adults ◽

Young Adults ◽

Age Groups ◽

Young Group ◽

Self Administration ◽

Behavioral Measures ◽

Younger Adults ◽

Different Types ◽

Before And After ◽

Aging Adults

In recent years of expanding legalization, older adults have reported the largest increase in cannabis use of any age group. While its use has been studied extensively in young adults, little is known about the effects of THC in older adults and whether the risks of cannabis might be different, particularly concerning intoxication and cognition. The current study investigated whether age is associated with the deleterious effects of THC on cognitive performance and other behavioral measures before and after ad libitum self-administration of three different types of cannabis flower (THC dominant, THC + CBD, and CBD dominant). Age groups consisted of young adults (ages 21–25) and older adults (ages 55–70). Controlling for pre-use scores on all measures, the THC dominant chemovar produced a greater deleterious effect in younger adults compared with older adults in tests of learning and processing speed, whereas there were no differences between old and young in the effects of the other chemovars. In addition, the young group reported greater cannabis craving than the older group after using the THC chemovar. Consistent with some reports in the preclinical literature, the findings suggest that older adults may be less sensitive to the effects of THC on cognitive and affective measures.

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Housing Transitions and Recovery of Older Adults Following Hurricane Sandy

The Journals of Gerontology Series B ◽

10.1093/geronb/gby126 ◽

2018 ◽

Vol 74 (6) ◽

pp. 1041-1052 ◽

Cited By ~ 2

Author(s):

Alexis A Merdjanoff ◽

Rachael Piltch-Loeb ◽

Sarah Friedman ◽

David M Abramson

Keyword(s):

Older Adults ◽

Age Groups ◽

Family Health ◽

Hurricane Sandy ◽

Younger Adults ◽

Younger Age ◽

Observational Cohort ◽

Emergency Housing ◽

Young Old ◽

Post Disaster

Abstract Objectives This study explores the effects of social and environmental disruption on emergency housing transitions among older adults following Hurricane Sandy. It is based upon the Sandy Child and Family Health (S-CAFH) Study, an observational cohort of 1,000 randomly sampled New Jersey residents living in the nine counties most affected by Sandy. Methods This analysis examines the post-Sandy housing transitions and recovery of the young-old (55–64), mid-old (65–74), and old-old (75+) compared with younger adults (19–54). We consider length of displacement, number of places stayed after Sandy, the housing host (i.e., family only, friends only, or multi-host), and self-reported recovery. Results Among all age groups, the old-old (75+) reported the highest rates of housing damage and were more likely to stay in one place besides their home, as well as stay with family rather than by themselves after the storm. Despite this disruption, the old-old were most likely to have recovered from Hurricane Sandy. Discussion Findings suggest that the old-old were more resilient to Hurricane Sandy than younger age groups. Understanding the unique post-disaster housing needs of older adults can help identify critical points of intervention for their post-disaster recovery.

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Colorectal Cancer in Young and Older Adults in Uruguay: Changes in Recent Incidence and Mortality Trends

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18158232 ◽

2021 ◽

Vol 18 (15) ◽

pp. 8232

Author(s):

Carina Musetti ◽

Mariela Garau ◽

Rafael Alonso ◽

Marion Piñeros ◽

Isabelle Soerjomataram ◽

...

Keyword(s):

Colorectal Cancer ◽

Older Adults ◽

Cancer Incidence ◽

Age Groups ◽

Incidence Rates ◽

Mortality Trends ◽

Screening Programs ◽

Lifestyle Risk Factors ◽

Incidence And Mortality ◽

Colorectal Cancer Incidence

Uruguay has the highest colorectal cancer incidence rates in Latin America. Previous studies reported a stable incidence and a slight increase in mortality among males. We aimed to assess colorectal cancer incidence (2002–2017) and mortality trends (1990–2017) by age groups and sex, using data from the National Cancer Registry. Annual percent changes (APCs) were estimated using joinpoint regression models. We included 27,561 colorectal cancer cases and 25,403 deaths. We found an increasing incidence among both males and females aged 40–49, with annual increases of 3.1% (95%CI: 1.21–5.03) and 2.1% (95%CI: 0.49–3.66), respectively, and an increasein the rate in older males (70+) of 0.60% (95%CI: 0.02–1.20) per year between 2002 and 2017. Mortality remained stable among those younger than 50, whereas it decreased for older females aged 50–69 and 70+ (APC: −0.61% (−1.07–0.14) and −0.68% (−1.02–0.34), respectively), and increased for the oldest males (70+; APC: 0.74 (0.47–1.01)). In conclusion, we found rising colorectal cancer incidence accompanied by stable mortality in young adults. Sex disparities were also found among the older adults, with a more favorable pattern for females. Exposures to dietary and lifestyle risk factors, and inequalities in access to and awareness of screening programs, are probably among the main underlying causes and deserve further investigation.

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Structural differences in the semantic networks of younger and older adults

10.31234/osf.io/s73dp ◽

2018 ◽

Cited By ~ 2

Author(s):

Dirk U. Wulff ◽

Thomas Hills ◽

Rui Mata

Keyword(s):

Older Adults ◽

Cognitive Modeling ◽

Semantic Network ◽

Semantic Networks ◽

Edge Weight ◽

Younger Adults ◽

Age Related ◽

Weight Distributions ◽

Path Lengths ◽

First Time

Cognitive science invokes semantic networks to explain diverse phenomena from reasoning to memory retrieval and creativity. While diverse approaches are available, researchers commonly assume a single underlying semantic network that is shared across individuals. Yet, semantic networks are considered the product of experience implying that individuals who make different experiences should possess different semantic networks. By studying differences between younger and older adults, we demonstrate that this is the case. Using a network analytic approach and diverse empirical data, we present converging evidence of age-related differences in semantic networks of groups and, for the first time, individuals. Specifically, semantic networks of older adults exhibited larger degrees, less clustering, and longer path lengths. Furthermore, the edge weight distributions of older adults individual networks exhibited significantly more skew and higher entropy across node pairs and, except for unrelated node pairs, less inter-individual agreement, suggesting that older adults networks are generally more distinct than younger adults networks. Our results challenge the common conception of a single semantic network shared by individuals and highlight the importance of individual differences in cognitive modeling. They also present valuable benchmarks to discern between theories of age-related changes in cognitive performance.

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Risks of Stroke Recurrence and Mortality After First and Recurrent Strokes in Denmark: A Nationwide Registry Study

Neurology ◽

10.1212/wnl.0000000000013118 ◽

2021 ◽

pp. 10.1212/WNL.0000000000013118

Author(s):

Nils Skajaa ◽

Kasper Adelborg ◽

Erzsébet Horváth-Puhó ◽

Kenneth J Rothman ◽

Victor W. Henderson ◽

...

Keyword(s):

Ischemic Stroke ◽

Intracerebral Hemorrhage ◽

Risk Score ◽

Recurrent Stroke ◽

Recurrent Event ◽

Risk Scores ◽

Stroke Recurrence ◽

Stroke Severity ◽

Risk Of Death ◽

First Time

Background and Objectives:To examine risks of stroke recurrence and mortality after first and recurrent stroke.Methods:Using Danish nationwide health registries, we included patients (age ≥18 years) with first-time ischemic stroke (N = 105,397) or intracerebral hemorrhage (N = 13,350) during 2004–2018. Accounting for the competing risk of death, absolute risks of stroke recurrence were computed separately for each stroke subtype and within strata of age groups, sex, stroke severity, body mass index, smoking, alcohol, the Essen stroke risk score, and atrial fibrillation. Mortality risks were computed after first and recurrent stroke.Results:After adjusting for competing risks, the overall 1-year and 10-year risks of recurrence were 4% and 13% following first-time ischemic stroke and 3% and 12% following first-time intracerebral hemorrhage. For ischemic stroke, the risk of recurrence increased with age, was higher for men and following mild than more severe stroke. The most marked differences were across Essen risk scores, for which recurrence risks increased with increasing scores. For intracerebral hemorrhage, risks were similar for both sexes and did not increase with Essen risk score. For ischemic stroke, the 1-year and 10-year risks of all-cause mortality were 17% and 56% after a first-time stroke and 25% and 70% after a recurrent stroke; corresponding estimates for intracerebral hemorrhage were 37% and 70% after a first-time event and 31% and 75% after a recurrent event.Conclusion:The risk of stroke recurrence was substantial following both subtypes, but risks differed markedly among patient subgroups. The risk of mortality was higher after a recurrent than first-time stroke.

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Human-Technology Interaction Factors Associated with Electronic Personal Health Records (ePHRs) Use Among Younger and Older Adult Users: A Secondary Data Analysis (Preprint)

10.2196/preprints.27966 ◽

2021 ◽

Author(s):

Yan Luo ◽

Krystal Dozier ◽

Carin Ikenberg

Keyword(s):

Older Adults ◽

Health Information ◽

Personal Health Record ◽

Age Groups ◽

Personal Health ◽

Younger Adults ◽

Clinical Notes ◽

Interaction Factors ◽

The Relationship ◽

Two Age Groups

BACKGROUND An electronic personal health record (ePHR), also known as a personal health record (PHR), was broadly defined as an electronic application through which individuals can access, manage, and share their health information in a secure and confidential environment. Although ePHRs can benefit individuals as well as caregivers and healthcare providers, the use of ePHRs among individuals continues to remain low. The relationship between age and ePHRs use has been documented in previous studies, which indicated younger age was related to higher ePHRs use, and patients who are younger were more likely to use ePHRs. OBJECTIVE The current study aims to examine the relationship between human-technology interaction factors and ePHRs use among adults, and then compare the different effects of human-technology interaction factors on ePHRs use between younger adults (18-54 years old) and older adults (55 years of age and over). METHODS We analyzed the from the Health Information National Trends Survey (HINTS5, Cycle 3) collected from U.S. adults aged 18 years old and over in 2019. Descriptive analysis was conducted for all variables and each item of ePHRs use. Bivariate tests (Pearson test for categorical variable and F-test for continuous variables) were conducted over four age groups. Lastly, adjusting for socio-demographics and healthcare resources, a weighted multiple linear regression was conducted to examine the relationship between human-technology interaction factors and ePHRs use. RESULTS The final sample size was 1,363 and divided into two age groups: 18-54 years old and 55 years of age and older. The average level of ePHRs use was low (Mean=2.76, range=0-8). There is no significant difference on average ePHRs use between two age groups. Including clinical notes was positively related to ePHRs use in both groups: 18-54 years old (beta=0.28, P<0.01), 55 years old and above (beta=0.15, P<0.01). While accessing ePHRs using a smartphone app was only associated with ePHRs use among younger adults (beta=0.29, P<0.001), ease to understand health information in ePHRs was positively linked to ePHRs use only among older adults (beta=0.13, P<0.01). CONCLUSIONS This study found that including clinical notes was positively related to ePHRs use in both age groups, which suggested that including clinical notes as a part of ePHRs might improve the effective use of ePHRs among patients. Moreover, accessing ePHRs using a smartphone app was associated with higher ePHRs use among younger adults while ease of understanding health information in ePHRs was linked to higher ePHRs use among older adults. The design of ePHRs should provide the option of being accessible through mobile devices to promote greater ePHRs use among young people. For older adults, providers could add additional notes to explain health information recorded in the ePHRs.

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Age Differences in the Malleability of Attitudes toward Automated Shared Mobility

Proceedings of the Human Factors and Ergonomics Society Annual Meeting ◽

10.1177/1071181321651250 ◽

2021 ◽

Vol 65 (1) ◽

pp. 128-128

Author(s):

Kathryn Baringer ◽

Dustin J. Souders ◽

Jeremy Lopez

Keyword(s):

Older Adults ◽

Older Adult ◽

Age Groups ◽

Educational Video ◽

Middle Aged ◽

Automated Vehicles ◽

Younger Adults ◽

Difference Scores ◽

Video Condition ◽

Middle Aged Adults

Introduction: The use of shared automated vehicles (SAVs) should lead to several societal and individual benefits, including reduced greenhouse gas emissions, reduced traffic, and improved mobility for persons who cannot safely drive themselves. We define SAVs as on-demand, fully automated vehicles in which passengers are paired with other riders traveling along a similar route. Previous research has shown that younger adults are more likely to report using conventional ridesharing services and are more accepting of new technologies including automated vehicles (AVs). However, older adults, particularly those who may be close to retiring from driving, stand to greatly benefit from SAV services. In order for SAVs to deliver on their aforementioned benefits, they must be viewed favorably and utilized. We sought to investigate how short educational and/or experiential videos might impact younger, middle-aged, and older adult respondents’ anticipated acceptance and attitudes toward SAVs. Knowing what types of introductory experiences improve different age groups’ perceptions of SAVs will be beneficial for tailoring campaigns aiming to promote SAV usage. Methods: We deployed an online survey using the platform Prolific for middle-aged and older respondents, and our departmental participant pool for younger adults, collecting 585 total responses that resulted in 448 valid responses. Respondents answered questions regarding their demographic attributes, their ridesharing history, preconceptions of technology, as well as their anticipated acceptance attitudes towards SAVs as measured by the dimensions of the Automated Vehicle User Perception Survey (AVUPS). After this, respondents were randomly assigned to an intervention condition where they either watched 1) an educational video about how SAVs work and their potential benefits, 2) an experiential video showing a AV navigating traffic, 3) both the experiential and educational videos, or 4) a control video explaining how ridesharing works. Anticipated acceptance attitudes towards SAVs were measured again after this intervention and difference scores calculated to investigate the effect of the intervention conditions. Prolific respondents were paid at a rate of $9.50/hour and younger adults received course credit. Results: Controlling for preconceptions of technology and ridesharing experience, a MANOVA was run on the difference scores of the dimensions of the AVUPS (intention to use, trust/reliability, perceived usefulness (PU), perceived ease of use (PEOU), safety, control/driving-efficacy, cost, authority, media, and social influence). Both older and middle-aged adults expressed significantly greater increases in PEOU and PU of SAVs than younger adults. We also observed an interaction between age and condition for both PU and PEOU. For PU, older adults’ difference scores were found to be significantly greater than younger adults’ for the control video condition. With PEOU, older adults’ difference scores were significantly greater than both younger adults’ for the control video condition, and middle-aged adults had greater difference scores for the educational-only video condition than younger or older adults. Discussion: The increases in PU observed for older adults in the control condition suggests that educating them on how to use currently available ridesharing services might transfer to and/or highlight the benefits that automated ridesharing might provide. The PEOU interactions also suggest that middle-aged adults might respond more positively than younger or older adults to an educational introduction to SAVs. Conclusion: The positive findings pertaining to PU and PEOU show that exposure to information related to SAVs has a positive impact on these attitudes. PU’s and PEOU’s positive relationship to behavioral intentions (BI) in the Technology Acceptance Model, coupled with the findings from this study, bode well for higher fidelity interventions seeking to inform and/or give individuals experience with SAVs. Providing information on how currently available ridesharing services work helped our older adult respondents recognize the potential usefulness of SAVs. Knowing that different age groups may respond better to educational versus experiential interventions, for example middle-aged adults in this study responding more positively to the educational video condition than younger or older adults, may be useful for targeted promotional campaigns.

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