Retinoblastoma as a Possible Primary Intracranial Tumor

Neurosurgery ◽  
1981 ◽  
Vol 9 (6) ◽  
pp. 706-709 ◽  
Author(s):  
Elizabeth Bullitt ◽  
Barbara J. Crain
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Intracranial Tumor ◽  
Intracranial Tumors ◽  
Retinal Lesion ◽  
The Central Nervous System ◽  
Primary Intracranial Tumor ◽  
Genetic Form

Abstract A 10-month-old infant with a small. unilateral, peripheral retinal lesion also had a large. well-encapsulated. suprasellar retinoblastoma. The primary vs. the metastatic nature of the intracranial tumor is considered. It is postulated that primary intracranial tumors may arise within areas of the central nervous system embryologically related to the retina in patients with the genetic form of retinoblastoma.

Presentation of central nervous system sarcoidosis as intracranial tumors

1985 ◽  
Vol 63 (6) ◽  
pp. 851-856 ◽  
Author(s):  
W. Craig Clark ◽  
James D. Acker ◽  
F. Curtis Dohan ◽  
Jon H. Robertson
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Pulmonary Involvement ◽  
Intracranial Tumor ◽  
Intracranial Tumors ◽  
Serum Angiotensin Converting Enzyme ◽  
Content Type ◽  
The Central Nervous System ◽  
A Site

✓ Five cases of sarcoid presenting as an intracranial tumor are reported. In one instance, the lesion presented as a tumor in the cerebellopontine angle, a site not previously reported for the initial presentation of sarcoid isolated to the central nervous system. The role of computerized tomography, surgery, and steroid therapy is discussed. In the absence of pulmonary involvement, serum angiotensin-converting enzyme levels do not appear to be helpful in predicting steroid response.

scholarly journals The microenvironment of brain metastases from solid tumors

2021 ◽  
Vol 3 (Supplement_5) ◽  
pp. v121-v132
Author(s):  
Ethan S Srinivasan ◽  
Krutika Deshpande ◽  
Josh Neman ◽  
Frank Winkler ◽  
Mustafa Khasraw
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Brain Metastases ◽  
Intracranial Tumor ◽  
Malignant Cells ◽  
Complex Interplay ◽  
Dismal Prognosis ◽  
Medical Need ◽  
Metabolic Conditions ◽  
The Central Nervous System

Abstract Brain metastasis (BrM) is an area of unmet medical need that poses unique therapeutic challenges and heralds a dismal prognosis. The intracranial tumor microenvironment (TME) presents several challenges, including the therapy-resistant blood–brain barrier, a unique immune milieu, distinct intercellular interactions, and specific metabolic conditions, that are responsible for treatment failures and poor clinical outcomes. There is a complex interplay between malignant cells that metastasize to the central nervous system (CNS) and the native TME. Cancer cells take advantage of vascular, neuronal, immune, and anatomical vulnerabilities to proliferate with mechanisms specific to the CNS. In this review, we discuss unique aspects of the TME in the context of brain metastases and pathways through which the TME may hold the key to the discovery of new and effective therapies for patients with BrM.

A CORRELATION OF CLINICOPATHOLOGICAL AND RADIOLOGICAL FINDINGS OF CENTRAL NERVES SYSTEM TUMOURS

2021 ◽  
pp. 17-20
Author(s):  
Monika hemin Shroff ◽  
Abhishek Rajawat ◽  
Kavita choudhary ◽  
Geeta w. Mukhiya
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Posterior Fossa ◽  
Annual Incidence ◽  
Cerebral Hemispheres ◽  
Cns Tumors ◽  
Intracranial Tumors ◽  
Radiological Findings ◽  
The Central Nervous System

The annual incidence of tumors of the central nervous system ranges from 10 to 17 per 100,000 persons for intracranial tumors and 1 to 2 per 100,000 persons for intraspinal tumors. Tumors of the CNS account for nearly 20% of all cancers of childhood. Seventy percent of childhood CNS tumors arise in the posterior fossa; a comparable number of tumors in adults arise within the cerebral hemispheres above the tentorium

scholarly journals Intracranial tumors of the central nervous system and air pollution – a nationwide case-control study from Denmark

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Aslak Harbo Poulsen ◽  
Ulla Arthur Hvidtfeldt ◽  
Mette Sørensen ◽  
Robin Puett ◽  
Matthias Ketzel ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Air Pollution ◽  
Nervous System ◽  
Case Control Study ◽  
Case Control ◽  
Intracranial Tumors ◽  
The Central Nervous System ◽  
Control Study

Clinical observation of a patient with thrombotic thrombocytopenic purpura with renal and intestinal lesions

2019 ◽  
Vol 91 (7) ◽  
pp. 106-110
Author(s):  
A G Stolyar ◽  
P V Avdonin ◽  
I E Valamina ◽  
E S Stolyarevich
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Thrombotic Microangiopathy ◽  
Clinical Observation ◽  
Pathological Process ◽  
Thrombocytopenic Purpura ◽  
Intestinal Lesions ◽  
The Central Nervous System ◽  
Genetic Form

The article presents a brief description of a rare disease - thrombotic thrombocytopenic purpura (Moshkovits - disease), which is based on the deficiency of ADAMTS-13 metalloproteinase, leading to the development of thrombotic microangiopathy with the defeat of vital organs. The article also describes the clinical observation of a patient with the Moshkovits - disease. The features of the above observation are involvement in the pathological process of the kidneys and intestines, while in the classical descriptions of the disease there is a predominant lesion of the Central nervous system, as well as the genetic form of the disease.

Dermoid/Epidermoid Tumors

2018 ◽  
Author(s):  
Ashish H. Shah ◽  
Jacques J. Morcos
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Central Nervous System ◽  
Nervous System ◽  
Cerebellopontine Angle ◽  
Intracranial Tumors ◽  
Imaging Findings ◽  
Resonance Imaging ◽  
Presenting Symptoms ◽  
The Central Nervous System

Epidermoid tumors of the central nervous system are typically found in the cerebellopontine angle or parasellar space and comprise approximately 1% of all intracranial tumors. Dermoid cysts tend to occur in midline locations. Both are derived from embryonal tissue and have classic imaging findings on computed tomography and magnetic resonance imaging. Epidermoid tumors and dermoid cysts are benign and grow slowly, although epidermoid cysts can undergo malignant transformation. Surgical decisions and approaches are based on the presenting symptoms and anatomic location of the tumor. Mollaret meningitis is a unique complication of these cysts and may occur if the cyst ruptures preoperatively or during surgery.

Radiological features of the meningoradicular metastases of tumors of the central nervous system

1973 ◽  
Vol 38 (5) ◽  
pp. 627-630
Author(s):  
Jean Pecker ◽  
Jacques Simon ◽  
Gilles Guy ◽  
Michel Carsin ◽  
Michel Jan
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Cauda Equina ◽  
Intracranial Tumors ◽  
Content Type ◽  
Radiological Features ◽  
The Central Nervous System ◽  
Radiological Studies ◽  
Fine Print

✓ The authors present two cases of intracranial tumors that metastasized through the CSF to the spinal cord and its roots, and discuss the value and hazards of radiological studies in making the diagnosis. Medulloblastomas, pinealomas, and ependymomas are the most common intracranial tumors to metastasize in this fashion. The metastases usually locate in the dural fundus and roots of the cauda equina due to the hydrodynamics of the CSF.

Effects of Hyperoxia on Lung Utrastructure

1970 ◽  
Vol 28 ◽  
pp. 26-27
Author(s):  
Gladys Harrison
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Light Microscopy ◽  
Oxygen Effects ◽  
Age Dependent ◽  
The Central Nervous System ◽  
The Subject ◽  
Space Age ◽  
Alveolar Septa ◽  
Extensive Damage

With the advent of the space age and the need to determine the requirements for a space cabin atmosphere, oxygen effects came into increased importance, even though these effects have been the subject of continuous research for many years. In fact, Priestly initiated oxygen research when in 1775 he published his results of isolating oxygen and described the effects of breathing it on himself and two mice, the only creatures to have had the “privilege” of breathing this “pure air”.Early studies had demonstrated the central nervous system effects at pressures above one atmosphere. Light microscopy revealed extensive damage to the lungs at one atmosphere. These changes which included perivascular and peribronchial edema, focal hemorrhage, rupture of the alveolar septa, and widespread edema, resulted in death of the animal in less than one week. The severity of the symptoms differed between species and was age dependent, with young animals being more resistant.

Sign in / Sign up

Export Citation Format

Share Document