scholarly journals Cell scientist to watch – Christine Faulkner

2020 ◽  
Vol 133 (24) ◽  
pp. jcs256826
Keyword(s):  
Cell Biology ◽  
Cell Communication ◽  
Plant Cells ◽  
Postdoctoral Position ◽  
Molecule Transport ◽  
University Of Edinburgh ◽  
The Uk ◽  
And Function ◽  
The University ◽  
Sydney Australia

ABSTRACTChristine Faulkner pursued her undergraduate degree at the University of Sydney, Australia. She then joined Robyn Overall's research group at the same institution to obtain her PhD in molecular and cell biology, where she characterised plasmodesmata, which are connection channels between plant cells that allow for communication and molecule transport. In 2005, Christine moved to the UK to continue studying plasmodesmata characterisation and function, as well as trying to understand their link to infection outcomes. Her first postdoctoral position was with Karl Oparka at the University of Edinburgh, followed by a second at the John Innes Centre in Norwich with Professor Andrew Maule. She subsequently joined the lab of Silke Robatzek at The Sainsbury Laboratory, also in Norwich, before starting an independent fellowship at Oxford Brookes University, in Oxford, in 2012. In December 2013, Christine returned to the John Innes Centre to establish her own lab. In 2016, she was awarded an ERC Consolidator grant. Her lab is trying to understand how cell–cell communication occurs in plants, focusing on plasmodesmata, and how this process is crucial for regulation of the plant immune response.

William Rutherford Sanders (1828–1881), anatomist, physician, linguist and museum conservator

2018 ◽  
Vol 28 (2) ◽  
pp. 120-123
Author(s):  
Dugald Gardner
Keyword(s):  
Neurological Disorders ◽  
Later Life ◽  
Structure And Function ◽  
Royal Infirmary ◽  
Abdominal Abscess ◽  
General Pathology ◽  
Consultant Physician ◽  
University Of Edinburgh ◽  
And Function ◽  
The University

William Rutherford Sanders spent a childhood and early student days divided between Edinburgh and Montpelier, France before graduating in Medicine in Edinburgh. An early interest in the spleen was encouraged by a two-year period in Europe where he became familiar with the work of Helmholtz, Bernard and Henle. Returning to Edinburgh, his growing experience led to the position of assistant in the Infirmary pathology department. He conducted classes in the University of Edinburgh and on behalf of the Royal Colleges became familiar with the museum of the Royal College of Surgeons where he was chosen as Conservator in 1853. Criticised by 20th century historians for concentrating on verbal teaching rather than on the conservation of the museum, Sanders became a consultant physician to the Royal Infirmary in 1861 and in 1869 Professor of General Pathology. Throughout these years, Sanders gave as much time as possible to the study of the structure and function of the spleen and to neurological disorders such as hemiplegia. His later life was interrupted by a series of illnesses commencing with an abdominal abscess. A prolonged convalescence allowed the resumption of work but deranged vision and hemiplegia preceded his death on 18 February 1881.

scholarly journals German Genetics Society Meeting 2009: Session VI

2009 ◽  
Author(s):  
Martin Fenner
Keyword(s):  
Cell Biology ◽  
Society Meeting ◽  
University Of Edinburgh ◽  
The University

Another guest post by Alex Knoll reporting from the German Genetics Society Meeting in Cologne.Saturday had two more sessions before the end of the meeting. Irina Stancheva from the Wellcome Trust Centre for Cell Biology at the University of Edinburgh ...

El informe sobre las implicaciones de la independencia de Escocia y su adhesión a la Unión Europea

2014 ◽  
pp. 981-1016
Author(s):  
Carlos COELLO MARTÍN ◽  
Fernando GONZÁLEZ BOTIJA
Keyword(s):  
International Law ◽  
Alternative Possibility ◽  
British Government ◽  
International Organisations ◽  
New States ◽  
University Of Edinburgh ◽  
Scottish Independence ◽  
The Uk ◽  
The University ◽  
The Eu

LABURPENA: Gobernu britainiarrak azterketa bat argitaratu du Eskozia burujabe batek ekarriko lituzkeen ondorioei buruz. Dokumentu horri erantsita doa bi irakasleren azterketa (James Crawford eta Alan Boyle, Edinburgoko Unibertsitatekoak), Eskoziaren burujabetza-erreferendumari buruzko alderdi juridikoak jorratuz. Bertan ondorioztatzen denez, Eskozia burujabe egiten bada, estatu berritzat hartuko da nazioarteko Zuzenbidearen ikuspegitik, eta gainerako estatuak oraingo Erresuma Batua ordeztuko luke, bere erakundeei eutsiz, eta bi estatu berri agertzearen ideia baztertuz. Horregatik, gainerako Erresuma Batuak orain kide den nazioarteko erakundeen kide izaten jarraituko luke, eta Eskoziak bere atxikipena eskatu beharko luke estatu berri gisa. Hala gertatuko litzateke, adibidez, Europar Batasunarekin. RESUMEN: El Gobierno britanico ha publicado un documento de analisis sobre las implicaciones que conllevaria una Escocia independiente. Como anexo a dicho documento se encuentra el estudio de dos profesores (James Crawford y Alan Boyle de la Universidad de Edimburgo) que analizan los aspectos juridicos del referendum sobre la independencia de Escocia. En ese estudio se concluye que si Escocia llega a ser independiente, se considerara como un nuevo Estado desde el punto de vista del Derecho internacional y el resto del actual Estado sucedera al actual Reino Unido, conservando sus instituciones, rechazandose la idea de que aparezcan dos nuevos Estados. Por ello el resto del Reino Unido continuaria como miembro de las organizaciones internacionales de las que es actualmente miembro, mientras que Escocia tendria que solicitar su adhesion como un nuevo Estado. Este seria el caso de la Union Europea. ABSTRACT: The British Government has published a major analysis paper on the implications of Scottish independence: ≪Scotland Analysis: Devolution and the Implications of Scottish Independence≫. The paper annexes an Opinion written by Professor James Crawford along with Professor Alan Boyle of the University of Edinburgh, entitled ‘Opinion: Referendum on the Independence of Scotland – International Law Aspects’. The Opinion concludes that if Scotland becomes independent, it will be considered a new state as a matter of international law and the remainder of the UK will continue the legal identity of the UK and retain its existing institutions generally uninterrupted. It rejects the alternative possibility that Scotland and the remainder of the UK will both be considered new states. The Opinion also concludes that one consequence of this is that the remainder of the UK will continue its membership of international organisations, whereas Scotland will have to join many of them as a new state. In particular, Scotland will have to join the EU as a new member state.

scholarly journals J. Murdoch Mitchison. 11 June 1922—17 March 2011

2019 ◽  
Vol 67 ◽  
pp. 279-306
Author(s):  
Peter Fantes ◽  
Sally Mitchison
Keyword(s):  
Cell Biology ◽  
Sea Urchins ◽  
Growth Cycle ◽  
Cell Physiology ◽  
Time Work ◽  
University Of Edinburgh ◽  
Membrane Changes ◽  
Post War ◽  
The University ◽  
Zoology Department

John Murdoch Mitchison, known as Murdoch, was elected FRS in recognition of his work on the cell cycle. This emerged from a lifelong interest in the natural sciences, interrupted by war-time work in Operational Research which developed his critical appraisal of research technique. Post-war, he completed a PhD at Cambridge, then worked with Sir Michael Swann FRS (1962) on mitotic membrane changes in sea urchins. In 1953 Murdoch joined the University of Edinburgh Zoology Department and in time switched his interest to the fission yeast Schizosaccharomyces pombe . Over the next 30 years he investigated cell growth and division, employing a meticulous approach to experiments. He considered there to be a ‘growth cycle’ in cells, independent of the DNA-division cycle. There is experimental evidence to support this idea, but further investigations of it have been limited. Actively fostering a relaxed but industrious and enquiring ethos in the lab, Murdoch ran the department jointly with Aubrey Manning. The Mitchison group's work at Edinburgh attracted students including Paul Nurse (later Sir Paul Nurse; FRS 1989, PRS 2010–2015), Béla Novak, Kim Nasmyth (FRS 1989) and Peter Fantes as well as many visiting academics. Murdoch's work on S. pombe came to both national and international recognition, forming a foundation for the current thriving community of researchers in cell physiology, cell genetics and molecular biology. Murdoch is remembered for his single-minded commitment to cell biology research and his generous, fair-minded support of younger colleagues and students. He was, additionally, an expert landscape gardener, a convivial host and phenomenally well-informed on most subjects.

scholarly journals Interview with 2020 Hooke medal winner Ian Chambers

2020 ◽  
Vol 133 (20) ◽  
pp. jcs254219
Keyword(s):  
Stem Cell ◽  
Stem Cell Research ◽  
Cell Biology ◽  
Embryonic Stem ◽  
British Society ◽  
Control Of Gene Expression ◽  
Erythroid Precursor ◽  
Cell Fate Decisions ◽  
University Of Edinburgh ◽  
The University

ABSTRACTIan Chambers studied biochemistry at the University of Strathclyde in Glasgow, UK. He then did his PhD in the laboratory of Paul Harrison at the Beatson Institute for Cancer Research, also in Glasgow. Ian studied the control of gene expression during the differentiation of erythroid precursor cells, discovering that the amino acid selenocysteine is encoded by UGA, which until then was thought to work only as a termination codon. Ian did his post-doctoral work on the regulation of the human immunodeficiency virus (HIV) with Paul Berg at Stanford University in California, USA. In 1991, he returned to Scotland to work on stem cell regulation with Austin Smith at the Centre for Genome Research (later the Institute for Stem Cell Research) at the University of Edinburgh, UK. During that time, Ian identified the transcription factor Nanog, which directs efficient embryonic stem cell self-renewal. Ian started his research group in 2006 at the University of Edinburgh, where he is also a Professor of Pluripotent Stem Cell Biology. His laboratory tries to understand the regulatory networks and transcription factors that control the identity of pluripotent embryonic stem cells, and how these modulate cell fate decisions during the differentiation process. Ian is now the Head of the Institute for Stem Cell Research at University of Edinburgh, an EMBO member and a Fellow of the Royal Society of Edinburgh. Ian is the recipient of the 2020 Hooke Medal from the British Society for Cell Biology (BSCB).

scholarly journals An interview with Jamie Davies

Development ◽  
2021 ◽  
Vol 148 (15) ◽  
Author(s):  
Seema Grewal
Keyword(s):  
Tissue Engineering ◽  
Developmental Biology ◽  
Public Engagement ◽  
Science Communication ◽  
Significant Contribution ◽  
British Society ◽  
University Of Edinburgh ◽  
The Uk ◽  
The University ◽  
Young Researchers

Jamie Davies is Professor of Experimental Anatomy at the University of Edinburgh. Spanning the fields of developmental biology, tissue engineering and synthetic biology, his research aims to understand the mechanisms by which cells organise themselves into tissues, focussing on the kidney. In addition to his research, Jamie is involved in science communication and public engagement, having written several books for specialist and non-specialist readers, and having given numerous public lectures and broadcasts. In April 2021, Jamie was awarded the inaugural Wolpert Medal from the British Society for Developmental Biology (BSDB), which is presented to outstanding developmental biologists who have made a significant contribution to teaching and communicating developmental biology in the UK. We spoke to Jamie to ask him about his cross-disciplinary research interests, his thoughts on public engagement and his advice for young researchers.

scholarly journals Social Pedagogy from a Scottish Perspective

2012 ◽  
Author(s):  
Mark Smith
Keyword(s):  
Social Welfare ◽  
Social Care ◽  
Policy Makers ◽  
Social Pedagogy ◽  
University Of Edinburgh ◽  
Scottish Government ◽  
Considerable Work ◽  
The Uk ◽  
Current Concerns ◽  
The University

There is growing interest across the UK around whether European models of social pedagogy might offer a conceptual framework within which to locate social care and social welfare work. Pilot programmes that seek to introduce and apply social pedagogical principles in practice settings are emerging, including in Scotland, where a joint BA run by The University of Aberdeen in conjunction with Camphill Schools was the first qualifying programme in social pedagogy in the UK. Many of these pockets of interest can seem only loosely connected to one another. ‘Scottish Conversations’, an initiative based around The University of Edinburgh, was conceived of to bring together practitioners, academics and policy makers with an interest in social pedagogy, to explore the possibilities and implications of introducing social pedagogical ways of working in Scotland. Considerable work has already been undertaken on this by the children’s charity ‘Children in Scotland’, supported by The Scottish Government. Our intention in this paper is to draw upon existing work and to encapsulate, within one document, key themes from the literature on social pedagogy, and to consider its relevance and possible application in a Scottish context. Specifically, we suggest that social pedagogy offers a means through which distinctively Scottish ideas around social welfare and education might be reframed in a way that resonates with current concerns about the role and direction of social work and social care more broadly. In this sense, we do not restrict our focus to areas of practice such as residential child care with which social pedagogy is most often associated, but consider its features to have relevance across a broad range of provision and professional groupings.

Protozoan paradigms for cell biology

1999 ◽  
Vol 112 (17) ◽  
pp. 2797-2798 ◽  
Author(s):  
K. Vickerman ◽  
G.H. Coombs
Keyword(s):  
Trypanosoma Brucei ◽  
Cell Biology ◽  
Antigenic Variation ◽  
Leishmania Species ◽  
Structure And Function ◽  
Holistic View ◽  
And Function ◽  
The University ◽  
Regius Professor ◽  
Made In

This article introduces a miniseries of three commentaries on parasite cell biology. The reviews were written as a tribute to Keith Vickerman FRS on his retirement as Regius Professor of Zoology at the University of Glasgow and are based on presentations given at a symposium held to honour his pioneering work in the field. On page 2799 of this issue, Michael Ferguson reviews the structure and function of GPI anchors, and the contributions that studies of trypanosomes have made. In subsequent issues, James Alexander, Abhay Satoskar and David Russell discuss Leishmania species as models of intracellular parasitism, and Michael Turner presents a holistic view of antigenic variation in Trypanosoma brucei infections.

scholarly journals T-cells play the classics with a different spin

2014 ◽  
Vol 25 (11) ◽  
pp. 1699-1703 ◽  
Author(s):  
Michael L. Dustin
Keyword(s):  
T Cells ◽  
Plasma Membrane ◽  
Immune Cells ◽  
Cell Biology ◽  
Immunological Synapse ◽  
Cell Communication ◽  
Intraflagellar Transport ◽  
Cell Types ◽  
Immune Synapse ◽  
And Function

The immune system uses much of the classic machinery of cell biology, but in ways that put a different spin on organization and function. Striking recent examples include the demonstration of intraflagellar transport protein and hedgehog contributions to the immune synapse, even though immune cells lack a primary cilium that would be the typical setting for this machinery. In a second example, lymphocytes have their own subfamily of integrins, the β2 subfamily, and only integrins in this family form a stable adhesion ring using freely mobile ligands, a key feature of the immunological synapse. Finally, we showed recently that T-cells use endosomal sorting complexes required for transport (ESCRTs) at the plasma membrane to generate T-cell antigen receptor–enriched microvesicles. It is unusual for the ESCRT pathway to operate at the plasma membrane, but this may allow a novel form of cell–cell communication by providing a multivalent ligand for major histocompatibility complex–peptide complexes and perhaps other receptors on the partnering B-cell. Immune cells are thus an exciting system for novel cell biology even with classical pathways that have been studied extensively in other cell types.

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