Blood catalase and haematocrit values in a breeding colony of Dutch-belted rabbits

2001 ◽  
Vol 35 (2) ◽  
pp. 140-146 ◽  
Author(s):  
R. H. Foote ◽  
E. Hare
Keyword(s):  
Genetic Correlation ◽  
Seminal Plasma ◽  
Catalase Activity ◽  
Preliminary Evidence ◽  
Age Effect ◽  
Breeding Colony ◽  
First Report ◽  
Rabbit Blood ◽  
Different Ages ◽  
Males And Females

Rabbit seminal plasma catalase is much higher than in the semen of other mammals, and differences appear to be inherited. Because of the scarcity of information on rabbit blood catalase and haematocrit in Dutch-belted rabbits, an investigation of possible effects of gender, age and genetics on these variables was undertaken. There were 191 rabbits sampled at 2-3 months, 130 at 12 months and 61 at 18-24 months of age. There was no age effect on the haematocrit values and on blood catalase activity. At 12 months of age males had an average haematocrit value of 44% compared with 40% for females ( P < 0.05). Corresponding average catalase values were 431 and 356 units/ml of blood ( P < 0.05). Also catalase was measured in the semen and blood of 34 males, and males differed in both their blood and semen catalase activity ( P < 0.05). The correlation between the two traits was r = 0.44. Heritability ( h2) estimates, based on 231 rabbits were 0.40 for blood catalase activity, and 0.26 for haematocrit. The genetic correlation between the two variables was 0.83 ( P < 0.05). These studies are consistent with the literature in that female rabbits have a slightly lower haematocrit value than males, and this is associated with a lower catalase activity. This appears to be the first report of a study that compares rabbit blood catalase in males and females of different ages. Preliminary evidence that differences may have a heritable basis is consistent with previous studies on rabbit semen catalase.

scholarly journals All-Cause and Cancer Mortality Trends in Macheng, China (1984–2013): An Age-Period-Cohort Analysis

2018 ◽  
Vol 15 (10) ◽  
pp. 2068
Author(s):  
Chunhui Li ◽  
Songbo Hu ◽  
Chuanhua Yu
Keyword(s):  
Cancer Mortality ◽  
Disease Surveillance ◽  
Cohort Analysis ◽  
Cohort Effect ◽  
Age Effect ◽  
Mortality Data ◽  
Period Effect ◽  
Mortality Trends ◽  
All Cause Mortality ◽  
Males And Females

The aim was to study the variation trends of all-cause and cancer mortality during 1984–2013 in Macheng City, China. The mortality data were collected from Macheng City disease surveillance points system and Hubei Center for Disease Control and Prevention. The model life table system was used to adjust mortality rates due to an under-reporting problem. An age-period-cohort model and intrinsic estimator algorithm were used to estimate the age effect, period effect, and cohort effect of all-cause mortality and cancer mortality for males and females. Age effect of all-cause mortality for both sexes increased with age, while the age effect of cancer mortality for both sexes reached a peak at the age group of 55–59 years old and then decreased. The relative risks (RRs) of all-cause mortality for males and females declined with the period and decreased by 51.13% and 63.27% during the whole study period, respectively. Furthermore, the period effect of cancer mortality in both sexes decreased at first and then increased. The cohort effect of all-cause and cancer mortality for both sexes born after 1904 presented the pattern of “rise first and then fall,” and decreased by 82.18% and 90.77% from cohort 1904–1908 to 1989–1993, respectively; especially, the risk of all-cause and cancer mortality for both sexes born before 1949 was much higher than that for those born after 1949.

scholarly journals Anti-Diarrheal Effects of Wood Creosote, Seirogan, in Japanese Patients

Reports ◽  
2019 ◽  
Vol 2 (4) ◽  
pp. 28
Author(s):  
Masanori Takagi ◽  
Masafumi Ito ◽  
Hirofumi Morino ◽  
Takanori Miura ◽  
Kyoichi Oshida ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Prescription Drug ◽  
Clinical Effectiveness ◽  
Japanese Patients ◽  
Clinical Use ◽  
Younger Patients ◽  
First Report ◽  
Males And Females ◽  
Wood Creosote

Wood creosote, Seirogan, is a non-prescription drug used to treat diarrhea. However, reports of its clinical use are rare. Here, we report the efficacy of wood creosote (3 capsules daily) in alleviating diarrheal symptoms in 148 patients from 10 clinics in Osaka, Japan. Wood creosote was classified to be remarkably effective, effective, partially effective, or not effective on the basis of the degree of alleviation of diarrheal symptoms. The anti-diarrheal efficacy of wood creosote soft capsules did not differ between males and females. Younger patients (21–30 years) showed greater improvement in diarrhea symptoms than elderly patients (>61 years) did. Wood creosote soft capsules were remarkably effective (44 patients), effective (71 patients), and partially effective (13 patients) in alleviating diarrhea symptoms due to a variety of causes. To the best of our knowledge, this is the first report on the clinical effectiveness of wood creosote soft capsules in treating diarrhea.

EFFECTS OF CHRONIC INTAKE OF ETHANOL ON RATE OF ETHANOL METABOLISM

1966 ◽  
Vol 44 (2) ◽  
pp. 241-257 ◽  
Author(s):  
Rosemary D. Hawkins ◽  
H. Kalant ◽  
J. M. Khanna
Keyword(s):  
Catalase Activity ◽  
Test Dose ◽  
Male Rats ◽  
Ethanol Metabolism ◽  
Total Daily Dose ◽  
Normal Male ◽  
Liver Alcohol Dehydrogenase ◽  
Wistar Strain ◽  
Daily Dose ◽  
Males And Females

In two separate studies of 6 and 12 weeks duration, adult male rats of the Wistar strain received ethanol in a total daily dose of about 9 g/kg. Growth rate was the same as that of glucose-treated controls. In comparison with controls of comparable weight, ethanol-treated rats showed significant increases in liver alcohol dehydrogenase (LAD) activity at all times after the first 2 weeks, but no significant change in catalase activity. The rate of disappearance of ethanol from the blood after a test dose was also significantly increased in the chronically treated rats, and the increase was initially comparable to that found in LAD activity. Later, the rate of ethanol disappearance rose more than could be explained by increased LAD activity. Normal male rats showed higher liver catalase activity than did normal females, but did not differ in LAD activity, which was higher at 9–10 weeks of age than in older or younger animals. It is suggested that failure of some investigators to find an alcohol-induced increase in LAD activity may be due to different responses by males and females.

Regulation of Catalase Activity in Mice of Different Ages

Gerontology ◽  
1971 ◽  
Vol 17 (2) ◽  
pp. 105-115 ◽  
Author(s):  
M.B. Baird ◽  
H.V. Samis
Keyword(s):  
Catalase Activity ◽  
Different Ages

A new species of Diomedenema (Nematoda, Rhabditida, Spiruromorpha) from Spheniscus magellanicus (Aves, Sphenisciformes) found on the southern coast of Brazil

2017 ◽  
Vol 92 (4) ◽  
pp. 514-519 ◽  
Author(s):  
M. Knoff ◽  
J.N. Santos ◽  
E.G. Giese ◽  
D.C. Gomes ◽  
Â.T. Silva-Souza
Keyword(s):  
New Species ◽  
Rio Grande ◽  
The State ◽  
Southern Coast ◽  
Rio Grande Do Sul ◽  
First Report ◽  
Spheniscus Magellanicus ◽  
The Third ◽  
Males And Females ◽  
A New Species

AbstractA new species of the genus Diomedenema, a spiruromorph nematode, collected from the lung of Spheniscus magellanicus (Sphenisciformes) found on the southern coast of the state of Rio Grande do Sul, Brazil, is described. The new species is differentiated from the only previously described species of the genus, D. diomedeae Johston & Mawson, 1952, by males possessing a set of caudal papillae with three pairs of precloacal, two pairs of adcloacal and one pair of postcloacal papillae; precloacal papillae with the papillae of the first two pairs being closer to each other than those of the third pair; a longer and pointed tail in males; and females with the vulva at mid-body. This is the first report of a nematode infecting the lung of a sphenisciforme host.

Retention of copper in the liver of sheep genetically selected for high and low concentrations of copper in plasma

1985 ◽  
Vol 41 (2) ◽  
pp. 219-226 ◽  
Author(s):  
J. A. Woolliams ◽  
G. Wiener ◽  
Carol Woolliams ◽  
N. F. Suttle
Keyword(s):  
Genetic Correlation ◽  
Dry Matter ◽  
Genetic Selection ◽  
Blood Samples ◽  
The Third ◽  
High Line ◽  
Low Concentrations ◽  
Different Ages ◽  
Female Sheep ◽  
Mountain Population

ABSTRACTThe extent to which genetic selection to change the concentration of copper (Cu) in plasma also affected the retention of Cu in the liver was assessed in three experiments. In each, the concentration of Cu was measured in samples of liver (taken by biopsy) and of plasma from female sheep of lines selected from a Scottish Blackface × Welsh Mountain population (which had previously been interbred for several generations) for high and low plasma Cu levels (high line and low line) and from purebred Scottish Blackface and Welsh Mountain females.The concentration of Cu in the liver and plasma was found to be consistently greater in high-line and Welsh Mountain than in low-line and Scottish Blackface females (P < 0·01) in the first experiment in which grazing animals were sampled at both 6 and 10 months of age and in the second, where sampling' was at 6 months only. Mean Cu concentrations in the liver ranged from 13 to 115 mg/kg dry matter (DM) and the correlations with those in plasma varied from 0·28 to 0·53 (all P < 0·05) and was highest when the concentration of Cu in the liver was lowest. The correlation between the concentrations of Cu in liver at different ages was 0·57 (P < 0·05).In the third experiment, 10-month-old high- and low-line females were given complete diets containing either 5, 10, 22 or 28 mg Cu per kg DM for 12 weeks. Liver samples were obtained at the beginning and end of this period and blood samples were taken every 3 weeks. The concentration of Cu in the liver was greater in high- than in low-line sheep on all diets and increased linearly with the Cu concentration of the diet but at a greater rate in the high line. At the end, the high line had significantly greater concentrations of Cu in plasma on the 5 and 10 mg Cu per kg DM diets.The experiments showed that high-line females retained more Cu in the liver than low-line females. It is most likely that this was caused by a positive genetic correlation between concentration of Cu in plasma and the efficiency of absorption of Cu.

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