scholarly journals The mongolian gerbil: qualitative and quantitative aspects of the cellular blood picture

1975 ◽  
Vol 9 (4) ◽  
pp. 283-287 ◽  
Author(s):  
Walter G. Dillon ◽  
Chester A. Glomski

The gerbil displays sex determined differences in packed red-cell volume, haemoglobin level, total leukocyte count and absolute number of circulating lymphocytes. The erythrocytes demonstrate a prominent polychromasia and frequent occurrence of basophilic stippling.

1973 ◽  
Vol 53 (2) ◽  
pp. 229-236 ◽  
Author(s):  
G. PELLETIER ◽  
L. J. MARTIN

Sheep were used to compare the anemia effects of fresh marrow-stem kale (Brassica oleracea var. acephala D.C.) with low-temperature dehydrated marrow-stem kale (MSK). There was a drop in hemoglobin (P < 0.01), packed-cell volume (P < 0.05), and red blood cell count (P < 0.05) after the 4th, 5th, and 6th wk, respectively, of feeding fresh MSK. Similar drops in hemoglobin (P < 0.05), packed-cell volume (P < 0.05), and red cell count (P < 0.05) occurred after the 4th wk of feeding dried MSK. Formation of Heinz-Ehrlich bodies peaked at the corresponding lowest values of hemoglobin and packed-cell volume for both fresh and dried MSK. These criteria returned almost to normal in the 2nd and 3rd wk after stopping the feeding of kale and using ground hay as the entire ration instead. It was concluded that high levels of either fresh or dried MSK could not be fed to sheep even for a relatively short period of time.


2021 ◽  
Author(s):  
Ananya Bhattacherjee ◽  
Prafulla Kumar Mohanty ◽  
Bandi Kumar Mallik

Abstract This study delineates influence of sex and age on haematological and cytometrical parameters in Japanese quail. Sixty birds were sampled, out of which 20 belong to each age-group (chicks, growers and adults). Haemoglobin, Total Erythrocyte Count, Packed Cell Volume, Erythrocyte indices, Total Leukocyte Count and Differential Leukocyte Count for all 3 age groups and cytometry of blood cells for chicks were analysed. Haemoglobin and packed cell volume of chicks differs significantly with other age-groups at p < 0.01. Significant differences at p = 0.01, p < 0.01 and p < 0.05 observed in lymphocytes, monocytes and Heterophil to Lymphocyte ratio between chicks and growers. Length, length to breadth, nuclear length, breadth, area and Nucleus to Cytoplasm of erythrocytes, length and area of lymphocytes, breadth and area of heterophils also vary significantly at p < 0.01 between Japanese quail chick male and female. Moreover, breadth of erythrocyte and length of heterophil differs significantly at p < 0.05 between two groups. Thus, age and sex influence physiology and hence haematology and may therefore affect egg and meat production.


Blood ◽  
1947 ◽  
Vol 2 (2) ◽  
pp. 154-163 ◽  
Author(s):  
EDITH SEYMOUR JONES ◽  
KEITH B. MCCALL ◽  
C. A. ELVEHJEM ◽  
P. F CLARK

Abstract 1. Rhesus monkeys fed purified rations supplemented with adequate amounts of the B vitamins, ascorbic acid, and whole liver substance maintained the following average blood picture: See PDF for Table 2. Natural diets or purified rations supplemented with liver extract do not support the above blood picture. The hemoglobin is lower and there is an increase in the range of the total leukocyte count and in the neutrophil-lymphocyte ratio to 2.0 ([unknown]). These figures are similar to the values in the literature and generally accepted as the normal. 3. Previous reports have shown the characteristic blood dyscrasias which develop when monkeys are fed certain B vitamin-deficient diets. These changes are summarized graphically in this paper. 4. The importance of determining the concentration of hemoglobin and the formed elements of the blood as a diagnostic test in nutritional studies has been shown.


Blood ◽  
1948 ◽  
Vol 3 (8) ◽  
pp. 896-910 ◽  
Author(s):  
ADOLPH J. CRESKOFF ◽  
THOMAS FITZ-HUGH ◽  
JOHN W. FROST

Abstract 1. The results of urethane therapy in 24 cases of leukemia are described. 2. The average daily dose is 4 Gm. orally or intravenously. 3. The drug is irregularly effective. Chronic myelogenous leukemia appears more responsive than the lymphatic variety. 4. Acute leukemias are not significantly altered in course by urethane. 5. Urethane produces a fall in the total leukocyte count in a majority of all types of leukemia. Clinical improvement does not necessarily follow. 6. Nausea is the most frequent side effect of urethane therapy. Possible marrow aplasia is the most dangerous toxic effect. 7. Urethane is of definite, but of limited value in the treatment of chronic leukemia. In some instances, it compares favorably with x-ray therapy, but in general, it is less dependable, particularly in its frequent failure to induce optimum return of normal red cell and platelet values, and optimum regression of organ infiltration.


1970 ◽  
Vol 6 (2) ◽  
pp. 203-210 ◽  
Author(s):  
MSH Khan ◽  
M Mostofa ◽  
MS Jahan ◽  
MA Sayed ◽  
MA Hossain

The experiment was performed on 25 adult mice, (Swiss albino), weighing about 25 gm, maintained on standard pellet diet and drinking water ad libitum. All the mice were randomly divided into five equal groups (5x5). Each group comprised of five mice was marked as group A, B, C, D and E. In the present study an attempt has been taken to study the effect of Garlic and vitamin B-complex in lead induced toxicities in mice with the observation of some parameters as toxic signs and body weight, some haematological parameters like total erythrocyte count (TEC), total leukocyte count (TLC), haemoglobin content (Hb%) and Packed cell volume (PCV), some biochemical parameters such as serum glutamate pyruvate transaminase SGPT/ALT, Serum glutamate Oxaloacetate transaminase (SGOT/AST) and postmortem changes in mice. An attempt was also made to estimate the residual deposition of lead in body tissues i.e. blood, liver, kidney, brain and bone in mice. Mice treated with lead acetate showed severe toxic signs and significantly reduced total erythrocyte count, total leukocyte count, haemoglobin content and packed cell volume and significant elevation of SGPT and SGOT. But in case of mice treated by lead acetate along with Garlic and vitamin B-complex showed almost normal levels of haematological and biochemical parameters. From this experiment it is revealed that Garlic and vitamin B-complex has protective and curative effect in lead toxicity. The mean body weight of mice of group B (only lead acetate) was significantly (p < 0.01) decreased, in comparison with the other treated groups. Lead acetate group also significantly reduced (p < 0.01) total erythrocyte count, packed cell volume and hemoglobin content was on 42 days of treatment. SGPT and SGOT were significantly elevated in all treated groups in comparison with control group. The liver of the mice of group B were blackish discoloration and enlarged. The significant reduction of lead in blood, liver and kidney was found in group E < C< D in comparison to group B (lead treated). The order of effectiveness was Garlic + Vitamin B- complex > Garlic > Vitamin Bcomplex. Key words: Garlic, vitamin B-complex, lead acetate, mice   doi: 10.3329/bjvm.v6i2.2337 Bangl. J. Vet. Med. (2008). 6 (2): 203-210


2019 ◽  
Vol 12 (2) ◽  

This study was conducted to diagnose of Babesia spp by using fluorescent microscope and light microscope, the study also included evaluating of Hemogram (RBC, HB, PCV, MCV, MCHC, Total Leukocyte Count, Differential Leukocyte Count) in cows infected with Babesia spp which cause piroplasmosis. The study included examination of 60 local breed Cows from many districts of Mosul city from the beginning of February 2018 until the end of July 2018, 17 were clinically infected with piroplasmosis and the infection was confirmed by using Giemsa and Acridine orange staining blood smears, and 10 cows were clinically intact and served as control. the results indicated that the percentage of the infection with Babesia spp was 28.33%, and the percentage of parasitemia ranged between (5-23%) with mean of (12.57%). The Results showed a statistical significant decrease (P<0.05) in RBC, Hb, and PCV values of diseased animals, Normocytic Normochromic type of anemia was found, the results also indicated a significant decrease in total Leukocyte count and neutrophil, with significant increase in lymphocytes number. the results also indicated non-significant changes in Eosinophil, Basophil and Monocyte numbers.


1965 ◽  
Vol 18 (1) ◽  
pp. 124 ◽  
Author(s):  
V Evans ◽  
HG Turner

The following red cell characters were studied in a herd of 217 calves repre-senting Brahman cross, Africander cross, Grade Brahman, and British (Hereford X Shorthorn) breeding, and in their dams: packed cell volume, haemoglobin level, red cell count, fragility, potassium and sodium concentrations, catalase activity, and haemoglobin type. There were distinct breed differences. In some characters, e.g. packed cell volume and potassium concentration, Africander cross were inter-mediate between Brahman cross and British, whereas in others, e.g. fragility and catalase activity, they were indistinguishable from British. Within breeds, the characters showed highly repeatable differences between animals and high herita-bilities.


2020 ◽  
Vol 2020 (1) ◽  
pp. 114-128
Author(s):  
Carmen Hové ◽  
Benjamin C Trumble ◽  
Amy S Anderson ◽  
Jonathan Stieglitz ◽  
Hillard Kaplan ◽  
...  

Abstract Background and objectives Among placental mammals, females undergo immunological shifts during pregnancy to accommodate the fetus (i.e. fetal tolerance). Fetal tolerance has primarily been characterized within post-industrial populations experiencing evolutionarily novel conditions (e.g. reduced pathogen exposure), which may shape maternal response to fetal antigens. This study investigates how ecological conditions affect maternal immune status during pregnancy by comparing the direction and magnitude of immunological changes associated with each trimester among the Tsimane (a subsistence population subjected to high pathogen load) and women in the USA. Methodology Data from the Tsimane Health and Life History Project (N = 935) and the National Health and Nutrition Examination Survey (N = 1395) were used to estimate population-specific effects of trimester on differential leukocyte count and C-reactive protein (CRP), a marker of systemic inflammation. Results In both populations, pregnancy was associated with increased neutrophil prevalence, reduced lymphocyte and eosinophil count and elevated CRP. Compared to their US counterparts, pregnant Tsimane women exhibited elevated lymphocyte and eosinophil counts, fewer neutrophils and monocytes and lower CRP. Total leukocyte count remained high and unchanged among pregnant Tsimane women while pregnant US women exhibited substantially elevated counts, resulting in overlapping leukocyte prevalence among all third-trimester individuals. Conclusions and implications Our findings indicate that ecological conditions shape non-pregnant immune baselines and the magnitude of immunological shifts during pregnancy via developmental constraints and current trade-offs. Future research should investigate how such flexibility impacts maternal health and disease susceptibility, particularly the degree to which chronic pathogen exposure might dampen inflammatory response to fetal antigens. Lay Summary This study compares immunological changes associated with pregnancy between the Tsimane (an Amazonian subsistence population) and individuals in the USA. Results suggest that while pregnancy enhances non-specific defenses and dampens both antigen-specific immunity and parasite/allergy response, ecological conditions strongly influence immune baselines and the magnitude of shifts during gestation.


1985 ◽  
Vol 14 (6) ◽  
pp. 345-356
Author(s):  
Michael G. Garner ◽  
Andrew F. Phippard ◽  
John S. Horvath ◽  
Geoffrey G. Duggin ◽  
David J. Tiller

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