Ascertainment and evaluation of interval cancers in population-based mammography screening programmes: a collaborative study in four European centres

Objectives: The purpose of the present study was to estimate the interval cancer (IC) rates in four population-based mammography screening programmes in four countries with different health-care environments, different access to cancer registry data, and different age groupsof women invited. Setting: The screening programmes in Coimbra (Portugal), Dublin (Ireland), Stockholm (Sweden), and Turin (Italy) participated in the study. Methods: All cancer cases were searched for in cancer registries. IC rates and other outcome measures from the screeningprogrammes were estimated and compared between the centres. Poisson regression model was used to estimate the proportional incidence based on IC rate in relation to expected total breast cancer incidence rate in the absence of screening. Results: There was a more than tenfold difference inthe number of invited women at the first round between the involved centres. The IC rates varied between 4.3 and 23.8 per 10,000 women screened. The levels of IC rates in relation to the estimated background incidence varied from 0.35 up to 0.46 depending on age groups involved in the programme,but did not differ significantly between three of the four involved centres. Conclusions: IC rates were quite similar between three of the four centres despite the differences in target population, invited ages, length of building-up of the programmes and different health-care organizations.Different access to complete cancer registry data is likely to explain the lower IC rates in the fourth centre.

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Distinct temporal trends in breast cancer incidence from 1997 to 2016 by molecular subtypes: A population-based study of Scottish cancer registry data

10.1101/19011411 ◽

2019 ◽

Author(s):

Ines Mesa-Eguiagaray ◽

Sarah H Wild ◽

Philip S. Rosenberg ◽

Sheila M Bird ◽

David H Brewster ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Registry ◽

Cancer Incidence ◽

Molecular Subtypes ◽

Breast Cancer Incidence ◽

Temporal Trends ◽

Population Based ◽

Registry Data ◽

Cancer Registry Data ◽

Er Status

AbstractBackgroundStrategies for breast cancer prevention are informed by assessing whether incidence differs by tumour biology. We describe temporal trends of breast cancer incidence by molecular subtypes in Scotland.MethodsPopulation-based cancer registry data on 72,217 women diagnosed with incident primary breast cancer from 1997 to 2016 were analysed. Age-standardised rates (ASR) and age-specific incidence were estimated by tumour subtype after imputing the 8% of missing oestrogen receptor (ER) status. Joinpoint regression and age- period- cohort models were used to assess whether significant differences were observed in incidence trends by ER status.ResultsER positive tumour incidence steadily increased particularly for women of screening age 50 to 69 years from 1997 till around 2011 (1.6%/year, 95%CI: 1.2 to 2.1). ER negative incidence decreased among all ages at a consistent rate of −0.7%/year (95%CI: −1.5, 0) from around 2000-2016. Compared to the 1941-1959 central birth cohort, women born 1912-1940 had lower incidence rate ratios (IRR) for ER+ tumours and women born 1960- 1986 had higher IRR for ER- tumours.ConclusionsWe show evidence of aetiologic heterogeneity of breast cancer. Future incidence and survival reporting should be monitored by molecular subtypes.

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Global patterns of breast cancer incidence and mortality: A population‐based cancer registry data analysis from 2000 to 2020

Cancer Communications ◽

10.1002/cac2.12207 ◽

2021 ◽

Author(s):

Shaoyuan Lei ◽

Rongshou Zheng ◽

Siwei Zhang ◽

Shaoming Wang ◽

Ru Chen ◽

...

Keyword(s):

Breast Cancer ◽

Data Analysis ◽

Cancer Registry ◽

Cancer Incidence ◽

Breast Cancer Incidence ◽

Population Based ◽

Registry Data ◽

Cancer Registry Data ◽

Incidence And Mortality ◽

Global Patterns

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CLL/SLL Is More Common Than Registry Incidence Suggests: A Population-Based Study in Manitoba, Canada.

Blood ◽

10.1182/blood.v106.11.1334.1334 ◽

2005 ◽

Vol 106 (11) ◽

pp. 1334-1334 ◽

Cited By ~ 1

Author(s):

Matthew D. Seftel ◽

Donna Hewitt ◽

Hui Zhang ◽

Donna Turner ◽

Spencer Gibson ◽

...

Keyword(s):

Flow Cytometry ◽

Cancer Registry ◽

Census Data ◽

Tertiary Care ◽

Cancer Registries ◽

Population Based ◽

Lymphocytic Leukemia ◽

Registry Data ◽

Population Based Study ◽

Cancer Registry Data

Abstract Background: The exact incidence of chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) is unknown. In the appropriate clinical setting, peripheral blood immunophenotyping is often sufficient for diagnosis. Cancer registries that rely only on histological or cytological reporting may inaccurately estimate the incidence of CLL/SLL. The province of Manitoba, with a population of 1.2 million people, has a centralized flow cytometry service as well as a provincial cancer registry. We thus had the opportunity to use these large databases to describe the demographic and clinical patterns of CLL/SLL. This has enabled us to test the hypothesis that registry data underestimates the incidence of this disease. Methods: All patients diagnosed with CLL/SLL between January 1, 1998 and December 31, 2003 were obtained from the Manitoba cancer registry and the central flow cytometry database. Additional clinical characteristics were obtained from a chart review. Results: 491 patients were diagnosed by flow cytometry. In contrast, cancer registry data reported 345 patients with CLL/SLL, 131 (38%) of which were diagnosed in tertiary care centres. Thus, 146 (30%) patients were not known to the provincial cancer registry. Median age of pts was 71 years (range, 24–97). Based on 2001 Canadian census data, the crude incidence of CLL/SLL in Manitoba is estimated to be 7 per 100 000 persons. Other demographic and clinical data of this population-based study will be presented. Conclusion: By incorporating diagnostic immunophenotyping, the incidence of CLL/SLL appears to be higher than that reported by a large Canadian cancer registry. This observation may apply to other local and national jurisdictions, and should be studied further.

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Distinct temporal trends in breast cancer incidence from 1997 to 2016 by molecular subtypes: a population-based study of Scottish cancer registry data

British Journal of Cancer ◽

10.1038/s41416-020-0938-z ◽

2020 ◽

Vol 123 (5) ◽

pp. 852-859 ◽

Cited By ~ 1

Author(s):

Ines Mesa-Eguiagaray ◽

Sarah H. Wild ◽

Philip S. Rosenberg ◽

Sheila M. Bird ◽

David H. Brewster ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Registry ◽

Cancer Incidence ◽

Molecular Subtypes ◽

Breast Cancer Incidence ◽

Temporal Trends ◽

Population Based ◽

Registry Data ◽

Population Based Study ◽

Cancer Registry Data

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Data from Population-based Cancer Registration for Secondary Data Analysis: Methodological Challenges and Perspectives

Das Gesundheitswesen ◽

10.1055/a-1009-6466 ◽

2019 ◽

Vol 82 (S 01) ◽

pp. S62-S71 ◽

Cited By ~ 1

Author(s):

Volker Arndt ◽

Bernd Holleczek ◽

Hiltraud Kajüter ◽

Sabine Luttmann ◽

Alice Nennecke ◽

...

Keyword(s):

Data Analysis ◽

Cancer Registry ◽

Secondary Data ◽

Cancer Registries ◽

Population Based ◽

Secondary Data Analysis ◽

Data Availability ◽

Registry Data ◽

Cancer Registration ◽

Cancer Registry Data

AbstractPopulation-based cancer registries have a long-standing role in cancer monitoring. Scientific use of cancer registry data is one important purpose of cancer registration, but use of cancer registry data is not restricted to cancer registries. Cancer registration in Germany is currently heading towards population-based collection of detailed clinical data. This development together with additional options for record linkage and long-term follow-up will offer new opportunities for health services and outcome research. Both regional population-based registries and the German Centre for Cancer Registry Data (ZfKD) at the Robert Koch-Institute as well as international cancer registries and consortia or organizations may provide external researchers access to individual or aggregate level data for secondary data analysis. In this review, we elaborate on the access to cancer registry data for research purposes, availability of specific data items, and options for data linkage with external data sources. We also discuss as well as on limitations in data availability and quality, and describe typical biases in design and analysis.

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