Association of Thiamine Intake with Human Papillomavirus (HPV) Infection in American Women: A Secondary Data Analysis Based on the National Health and Nutrition Examination Survey from 2003 to 2016

Nearly all cases of cervical cancer are attributable to human papillomavirus (HPV), making it a significant women’s health issue. Though there have been advances in the prevention of HPV via vaccination, significant barriers continue to suppress vaccination rates for girls. Delaying vaccination until after sexual debut increases a woman’s chance of HPV infection, but there has been no quantification of this risk in the literature. The present study sought to address this gap via secondary data analysis with 173 female participants from the 2015–2016 National Health and Nutrition Examination Survey dataset. Results indicate that women in the sample who received the HPV vaccine after their sexual debut were 2.63 times more likely than women who receive the vaccine before their sexual debut to report an HPV diagnosis. These results have clear public and sexual health implications.

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Concurrent and Concordant Oral and Genital High-Risk Human Papillomavirus in the United States: Results from the National Health and Nutrition Examination Survey

The Journal of Infectious Diseases ◽

10.1093/infdis/jiaa519 ◽

2020 ◽

Author(s):

James Custer ◽

Riddhi Patel ◽

George L Delclos ◽

Stacia M DeSantis

Keyword(s):

United States ◽

Human Papillomavirus ◽

High Risk ◽

National Health ◽

The United States ◽

Hpv Infection ◽

High Rate ◽

Nutrition Examination Survey ◽

Sex Partners ◽

Health And Nutrition

Abstract Background Oropharyngeal cancers associated with high-risk human papillomavirus (HR-HPV) infection are increasing in the United States, especially among men. We evaluated the prevalence and predictors of concurrent (genital and oral) and concordant (same-type) HR-HPV infections in the United States. Methods We used the National Health and Nutrition Examination Survey from 2009 to 2016. Predictors were assessed via multivariable logistic regression. Results Among 10 334 respondents, 172 (2.1%) had concurrent infections (109 [3.5%] men and 63 [0.76%] women]. Ninety-three (1.0%) had concordant infections (54 [1.6%] men and 39 [0.5%] women). Predictors of concurrence in men included the following: no longer married versus married (odds ratio [OR], 2.3; 95% confidence interval [CI], 1.3–4.9), living with a partner versus married (3.0; 1.2–7.5), and having 2–5 lifetime oral sex partners (3.0; 1.2–7.5). In women they included the following: no longer married versus married (3.6; 1.3–10.3), ≥2 recent sex partners (4.6; 1.4–15.6 for 2–5 partners and 3.9; 1.1–14.3 for ≥6 partners), and marijuana use (2.2; 1.0–4.5). The predictor of concordance in men and women was no longer married versus married (3.5; 1.2–9.9 in men and 3.2; 1.1–9.4 in women). Conclusions Concurrent and concordant HR-HPV infections occur at a high rate, especially among men, and are associated with behavioral factors. This underscores the importance of HPV vaccination, screening, and education in men.

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