Research Progress on the Relationship between Intestinal Flora, Immune System and Glioma

2021 ◽  
Vol 11 (10) ◽  
pp. 4357-4364
Author(s):  
灵峰 潘
2019 ◽  
Vol 117 ◽  
pp. 109138 ◽  
Author(s):  
Quantao Ma ◽  
Yaqi Li ◽  
Pengfei Li ◽  
Min Wang ◽  
Jingkang Wang ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Monika Adamczyk-Sowa ◽  
Aldona Medrek ◽  
Paulina Madej ◽  
Wirginia Michlicka ◽  
Pawel Dobrakowski

Aim.Evaluation of the impact of gut microflora on the pathophysiology of MS.Results. The etiopathogenesis of MS is not fully known. Gut microbiota may be of a great importance in the pathogenesis of MS, since recent findings suggest that substitutions of certain microbial population in the gut can lead to proinflammatory state, which can lead to MS in humans. In contrast, other commensal bacteria and their antigenic products may protect against inflammation within the central nervous system. The type of intestinal flora is affected by antibiotics, stress, or diet. The effects on MS through the intestinal microflora can also be achieved by antibiotic therapy andLactobacillus. EAE, as an animal model of MS, indicates a strong influence of the gut microbiota on the immune system and shows that disturbances in gut physiology may contribute to the development of MS.Conclusions.The relationship between the central nervous system, the immune system, and the gut microbiota relates to the influence of microorganisms in the development of MS. A possible interaction between gut microbiota and the immune system can be perceived through regulation by the endocannabinoid system. It may offer an opportunity to understand the interaction comprised in the gut-immune-brain axis.


2019 ◽  
Vol 78 ◽  
pp. 01008
Author(s):  
Weiliang Wang

Allergic diseases are the major health problems in the world today. The abnormal structure of intestinal flora is closely related to the occurrence and development of allergic diseases. The formation process of intestinal flora structure in early life is affected by various factors such as delivery mode, feeding mode, addition of probiotics or prebiotics, and heredity, etc. Moreover, the abnormal intestinal flora structure in early life is an important influencing factor for later allergic diseases. In this paper, the relationship between early intestinal flora structure abnormality and the occurrence and development of allergic diseases is discussed in combination with the latest literature.


2020 ◽  
Vol 10 (06) ◽  
pp. 295-305
Author(s):  
Huang Tao ◽  
Chun-Ru Wang ◽  
Jun-Cheng Guo ◽  
Min Guo

2020 ◽  
Vol 9 (2) ◽  
pp. 40
Author(s):  
Yang Hui ◽  
Junming Hou ◽  
Yong Jia ◽  
Ming Dong ◽  
Feixue Feng ◽  
...  

<p>Cancer is a common chronic disease all over the world, which will cause serious health burden. At present, the debate about the role of intestinal flora in the prevention and control of cancer has always existed. Therefore, researchers should pay close attention to the impact of intestinal flora on several cancers (such as colon cancer, liver cancer and breast cancer). In addition, it is reported that intestinal flora may also affect the efficacy of cancer chemotherapy and immunotherapy. This paper introduces some energy research results to help clear the relationship between intestinal flora and cancer, even cancer micro environment. It can help clarify the mist of cancer and gut microbiota, let those little creatures to serve the progress of improving mankind living condition and of health and medicine.</p>


Author(s):  
Zezhen Wu ◽  
Yongru Chen ◽  
Dan Zhu ◽  
Yingmiao Zheng ◽  
Khan Barkat Ali ◽  
...  

Background: Intestinal microecology is the largest and most complex human microecology. The intestinal microflora plays an important role in human health. Imbalance of intestinal microflora contributes to the occurrence and development of many diseases. Recently, the treatment of human diseases by regulating intestinal microflora has become a research topic of interest. Traditional Chinese medicine considers the whole human body as the central concept in disease treatment strategies. It advocates maintaining the coordination and balance of the functions of various organs and systems of the human body, including the intestinal microflora. Traditional Chinese medicine improves the metabolism and immune function of the human body by regulating the intestinal microflora. The intestinal microflora could trigger pharmacological activity or reduce toxicity of drugs through regulating metabolism, which enables traditional Chinese medicine formulations to exert their best therapeutic effects. Methods: This review summarized the relationship between the intestinal microflora and digestive system, tumors, and other diseases. Furthermore, the role of traditional Chinese medicine in the treatment of tumors, and other diseases is discussed. The relationship among traditional Chinese medicine and the common intestinal microflora, pathogenesis of human diseases, and effective intervention methods were elaborated. In addition, we explored the research progress of traditional Chinese medicine in the treatment of various human diseases by regulating intestinal microflora to provide new treatment concepts. Results: There is a close relationship between traditional Chinese medicine and the intestinal microflora. Traditional Chinese medicine formulations contribute to maintain the natural balance of the intestinal tract and the intestinal microflora to achieve treatment effects. This paper summarizes the mechanism of action of traditional Chinese medicine formulations in regulating the intestinal microflora in the prevention and treatment of various diseases. Furthermore, it summarizes information on the application of the interaction between traditional Chinese medicine preparations and regulation of intestinal microflora in the treatment of common human diseases. Conclusion: Intestinal microflora plays a key role in traditional Chinese medicine in maintaining the natural balance of physiology and metabolism of human body. It will provide a theoretical basis for the traditional Chinese medicine preparations in the prevention and treatment of common human diseases, and simulate future research on this aspect.


2020 ◽  
Vol 21 (15) ◽  
pp. 1603-1615
Author(s):  
Eva Alvarez-Vieites ◽  
Arora López-Santamarina ◽  
José M. Miranda ◽  
Alicia del Carmen Mondragón ◽  
Alexandre Lamas ◽  
...  

In recent decades, there has been a very rapid increase in the prevalence of diabetes globally, with serious health and economic implications. Although today there are several therapeutic treatments for this disease, these do not address the causes of the disease and have serious side effects, so it is necessary to seek new treatments to replace or complement the existing ones. Among these complementary treatments, a strong link between the intestinal microbiota and diabetes has been demonstrated, which has focused attention on the use of biotherapy to regulate the function of the intestinal microbiota and, thus, treat diabetes. In this way, the main objective of this work is to provide a review of the latest scientific evidence on diabetes, gathering information about new trends in its management, and especially, the influence of the intestinal microbiota and microbiome on this pathology. It is possible to conclude that the relationship between the intestinal microbiota and diabetes is carried out through alterations in energy metabolism, the immune system, changes in intestinal permeability, and a state of low-intensity systemic inflammation. Although, currently, most of the experimental work, using probiotics for diabetes management, has been done on experimental animals, the results obtained are promising. Thus, the modification of the microbiota through biotherapy has shown to improve the symptoms and severity of diabetes through various mechanisms related to these alterations.


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