scholarly journals Genetic Polymorphisms of Cyp19 and Myostatin Genes in Turkish Indigenous Sheep Breeds

2018 ◽  
Vol 68 (3) ◽  
pp. 313
Author(s):  
I. AKIŞ ◽  
F. ESEN GÜRSEL ◽  
N. HACIHASANOĞLU ÇAKMAK ◽  
G. ATMACA ◽  
H. YARDIBI ◽  
...  
Keyword(s):  
Growth Traits ◽  
Muscle Growth ◽  
Reproductive Activity ◽  
Meat Production ◽  
Production Traits ◽  
Sheep Breeds ◽  
Indigenous Sheep ◽  
Estrogen Synthesis ◽  
Pcr Rflp ◽  
Cyp19 Gene

Growth and meat production traits are very important in sheep breeding. Cyp19 gene has a major role in reproductive activity and growth due to its function in estrogen synthesis. Another gene affecting growth traits is  Myostatin (MSTN) gene, which mainly regulates skeletal muscle growth. In this study allele frequencies of genetic polymorphism in Cyp19 and Myostatin genes were identified by PCR-RFLP method in five indigenous Turkish sheep breeds, Chiose, Imroz, Kivircik, Zom and Morkaraman. Digestion of Cyp19 gene with HaeIII only revealed uncut AA genotype and digestion of MSTN with DraI also revealed only uncut AA genotype. Both loci analyzed in this study were found to be monomorphic in five Turkish indigenous sheep breeds. These highly conserved parts of the two genes can be useful for molecular evolutionary studies in sheep. Further studies regarding association analysis of Cyp19 and MSTN in sheep should be conducted.

scholarly journals Dorper sheep cross breeding with Indigenous sheep breed in Ethiopia

2019 ◽  
Vol 4 (1) ◽  
pp. 36
Author(s):  
Desalegn Ayichew Walle
Keyword(s):  
Research And Development ◽  
Research Output ◽  
Sheep Breed ◽  
Meat Production ◽  
Cross Breeding ◽  
Sheep Breeds ◽  
Indigenous Sheep ◽  
Dorper Sheep ◽  
On Farm ◽  
Better Than

The objective of this review paper was to review dorper sheep cross breeding with indigenous sheep breed in Ethiopia. The paper reviewed and discussed the history of dorper breed introduction, research and development efforts in crossbreeding and their performance under on-station and on-farm management. Formal survey on farmers perception on Dorper cross sheep indicated that the crossbred dorper sheep have non selective feed behavior and excellent in meat production under farmer`s management. On other study showed that dorper sheep was not meet farmer interest in breeding sheep aspect because of black coat color. The performance of indigenous sheep and their crosses with Dorper varied as per the location, management, farming conditions and percentage of exotic blood level inheritance. Different research output by team of researchers on farm and on station performance evaluation of dorper indicated that crossbreds often outperformed their local contemporaries. Under on farm condition, body weight at different ages was significantly higher in 50% Dorper crosses as compared to their 25% and75% counter parts.On station birth weight of Dorper (3.39 3.8 kg) better than crossbreed (3.0 3.24 ± 0.04 kg) and local sheep (2.36 2.77 kg), respectively.While the mean weaning weight (14 16 kg) and yearling weight (26.95 32.43 ± 0.46 kg) of 50% Dorper crossbreed was better than indigenous sheep breeds. However, crossbred ewes and local sheep breeds did not differ in litter size. Dorper crosses with Afar under on station is not economically important due to lower weight in all aspects. Crossbreeding programs of dorper with indigenous sheep require strong research and development support from public service and non-governmental institutions for sustainable design, optimization, and implementation in clearly defined production environments.

scholarly journals Meat production characteristics of Turkish native breeds: I. Fattening, slaughter and carcass traits of lambs

1970 ◽  
Vol 48 (4) ◽  
pp. 666-672
Author(s):  
Y. Aksoy ◽  
M. Uğurlu ◽  
A. Önenç ◽  
E. Şirin ◽  
U. Şen ◽  
...  
Keyword(s):  
Carcass Traits ◽  
Sheep Breed ◽  
The Other ◽  
Meat Production ◽  
Muscle Area ◽  
Sheep Breeds ◽  
Indigenous Sheep ◽  
Dressing Percentage ◽  
Production Characteristics ◽  
Carcass Cuts

The present study was conducted to determine the slaughter and carcass traits of male lambs of the Akkaraman (A), Morkaraman (M), Awassi (IW), Karayaka (KR), Kıvırcık (KV) and Middle Anatolian Merino (MAM) sheep breeds. Fattening of all lambs started when they were at 90 days at weaning and finished when they reached bodyweight of 40 kg. The cold dressing percentage of lambs of A, M, and IW breeds were significantly lower than those of KV, KR and MAM. Fat depth and muscle area were significantly greater in KV and MAM lambs than those of the other breeds. There were significant differences among breeds in shoulder, leg and lean weights. Weights of back loin in KV and MAM lambs were significantly greater than those of the other breeds. The highest values for carcass fleshiness were obtained in MAM and IW lambs, but they had a significantly lower carcass fatness score. There were significant differences among the breeds in carcass compactness and leg conformation. The results of the present study indicated that A and MAM breeds could be recommended for desirable carcass characteristics.Keywords: Carcass cuts, indigenous sheep breed, intensive lamb finishing, meat formation, SEUROP classification

scholarly journals Effects of polymorphisms at <i>LEP</i>, <i>CAST</i>, <i>CAPN1</i>, <i>GHR</i>, <i>FABP4</i> and <i>DGAT1</i> genes on fattening performance and carcass traits in Simmental bulls

2017 ◽  
Vol 60 (2) ◽  
pp. 61-70 ◽  
Author(s):  
Sena Ardicli ◽  
Deniz Dincel ◽  
Hale Samli ◽  
Faruk Balci
Keyword(s):  
Average Daily Gain ◽  
Carcass Traits ◽  
Meat Production ◽  
The Novel ◽  
Nucleotide Polymorphisms ◽  
Production Traits ◽  
Single Nucleotide ◽  
Fattening Performance ◽  
Pcr Rflp ◽  
Fattening Period

Abstract. The aim of this study was to investigate the effects of single nucleotide polymorphisms (SNPs) at six candidate genes (LEP, CAST, CAPN1, GHR, FABP4 and DGAT1) on fattening performance and carcass traits of Simmental bulls in Turkey. The analysis covered a total of 81 Simmental bulls grown on a private farm that were randomly selected for their fattening period for use in this study. Genotyping was performed using the PCR-RFLP method. The S20T polymorphism at the CAST gene and the G316A polymorphism at the CAPN1 gene were associated with variation in final weight, fattening period, weight gain and average daily gain (P < 0.05). In addition, LEP A80V had a significant effect on hot and chilled carcass weight and dressing percentage (P < 0.05). There was no association between GHR S555G, FABP4 V110M and DGAT1 K232A markers with the traits analysed. These results suggested that focusing on the novel effects of LEP, CAST and CAPN1 gene polymorphisms on meat production traits might be useful for marker-assisted selection in Simmental cattle.

Effect of myog genotypes on growth rate and production traits in Hungarian Large White pigs

2006 ◽  
Vol 54 (3) ◽  
pp. 393-397 ◽  
Author(s):  
I. Anton ◽  
A. Zsolnai ◽  
I. Komlósi ◽  
A. Király ◽  
L. Fésüs
Keyword(s):  
Growth Rate ◽  
Birth Weight ◽  
Additional Data ◽  
Growth Traits ◽  
Production Traits ◽  
Large White ◽  
Weight Growth ◽  
Pcr Rflp ◽  
Rflp Assay ◽  
Lean Weight

The effect of the porcine myogenin (Myog) 3' polymorphism on birth weight, growth rate, carcass weight, lean weight, lean meat percentage and backfat thickness has been investigated in Hungarian Large White pigs. MYOG genotypes were determined by PCR-RFLP assay. The obtained MYOGA frequency value was 0.6275. Due to the small number of BB piglets the effect of the MYOG genotypes on birth weight was not significant; however, an increasing tendency was observed from genotype AA to BB. The growth rate difference between MYOG genotypes was significant: BB animals showed the highest growth rate values during the fattening period. Since few results are available on the possible use of MYOG gene polymorphism in selection to improve carcass and growth traits, by this study the authors hope to provide additional data on this particular subject.

mtDNA D-loop of Chinese main indigenous sheep breeds using PCR-RFLP

2007 ◽  
Vol 1 (3) ◽  
pp. 352-356
Author(s):  
Xianglong Li ◽  
Zengli Zhang ◽  
Yuanfang Gong ◽  
Zhengzhu Liu ◽  
Qing Jia ◽  
...  
Keyword(s):  
Sheep Breeds ◽  
Indigenous Sheep ◽  
Pcr Rflp ◽  
D Loop

scholarly journals Allele-specific expression reveals the phenotypic differences between thin- and fat-tailed sheep

2020 ◽  
Author(s):  
Junjie Shao ◽  
Sangang He ◽  
Xiangyu Pan ◽  
Zhirui Yang ◽  
Hojjat Asadollahpour Nanaei ◽  
...  
Keyword(s):  
Gene Expression ◽  
Fat Deposition ◽  
Meat Production ◽  
Production Traits ◽  
Specific Expression ◽  
Allele Specific Expression ◽  
Phenotypic Differences ◽  
Sheep Breeds ◽  
Muscle Tissues ◽  
Allele Specific

Abstract Background: The thin-tailed sheep breeds from Europe and the fat-tailed sheep breeds from China exhibit distinct phenotypic differences in fat deposition and meat production traits. However, the molecular mechanisms underlying gene expression related to these phenotypic differences are not well understood. Allele-specific expression (ASE) refers to the significant imbalance of expression levels of two parental alleles. Characterization of such events in F1 hybrid offspring generated from these two groups of sheep breeds can minimize the external factors influencing gene expression and reveal the variants with a cis -regulatory effect on gene expression. The aim of the present study was to investigate the genetic factors that influence different fat-deposition and meat production traits between thin- and fat-tailed sheep.Results: Fifteen F1 hybrids were generated from crosses between Texel and Kazakh sheep as the representative phenotypes of thin- and fat-tailed breeds, respectively. Totally, 33 whole genomes from F1 individuals and their parents were sequenced with an average depth of ~17.21× coverage per sample. ASE analysis results from 70 RNA-seq samples of adipose and skeleton muscle tissues showed 128 ASE candidate genes were related to the function of fat deposition and meat production traits. A genome-wide scan of selective sweeps was also conducted between these two groups of sheep breeds in an effort to identify genomic regions related to fat deposition and meat production, respectively. We detected signatures of selection in ASE genes associated with fat deposition (e.g., PDGFD ) and meat production traits (e.g., LRCC2 ). Further analysis suggested that PDGFD and LRCC2 genes were speculated to be causative genes for fat deposition and meat production traits in sheep, respectively. Furthermore, AMPK signaling pathway was significantly enriched in ASE genes related to fatty acid biosynthesis in both adipose and skeleton muscle tissues, while PPAR signaling pathway was significantly enriched in ASE genes related to lipid metabolism in adipose tissue. Conclusions: Our finding illustrates that the expression of identified ASE genes could potentially lead to the differences in traits of fat deposition and meat production between thin- and fat-tailed sheep. Keywords: allele-specific expression, phenotypic difference, thin- and fat-tailed sheep, whole-genome sequencing, transcriptome

scholarly journals Some reproductive and growth traits of crossbred genotypes produced by crossing local sheep breeds of Kivircik x White Karaman and Chios x White Karaman in steppe conditions

2006 ◽  
Vol 49 (1) ◽  
pp. 55-63 ◽  
Author(s):  
N. Unal ◽  
H. Akcapinar ◽  
F. Atasoy ◽  
M. Aytac
Keyword(s):  
Birth Weight ◽  
Survival Rate ◽  
Reproductive Performance ◽  
Mediterranean Climate ◽  
Growth Traits ◽  
Survival Rates ◽  
Production Traits ◽  
Climate Conditions ◽  
Sheep Breeds ◽  
Survival And Growth

Abstract. The aim of this study was to investigate some production traits of crossbred genotypes produced for lamb production by crossing local sheep breeds of Kivircik (K) x White Karaman (W) and Chios (C) x White Karaman in steppe conditions. W breed is raised in steppe conditions while K and C breeds are raised in Mediterranean climate conditions in Turkey. A total of 340 ewes was used through 3 years. The litter size for W, KWF1 and CWF1 ewes were 1.26, 1.19 and 1.52 (P<0.05), respectively. The least squares means of W, KW F2, KW B1, CW F2 and CW B1 lambs were 91.2, 95.7, 95.6, 87.3 and 94.2 % for survival rate at weaning (90 days); 4.4, 4.3, 4.1, 4.2 and 4.1 kg for birth weight; 21.1, 20.3, 19.6, 20.3 and 19.9 kg for weaning weight; 31.9, 29.4, 30.3, 30.5 and 30.1 kg for 180 day weight, respectively. The differences among genotypes for survival rates and growth performance of lambs were not statistically significant (P>0.05). The results indicated that Chios crossbred ewes had the highest reproductive performance while all genotypes had similar performance in terms of survival and growth of lambs in steppe conditions.

scholarly journals Single Nucleotide Polymorphisms of Porcine lncMGPF Regulate Meat Production Traits by Affecting RNA Stability

2021 ◽  
Vol 9 ◽  
Author(s):  
Wei Lv ◽  
Shiyu Zhao ◽  
Yunqing Hou ◽  
Qian Tong ◽  
Yaxin Peng ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Myogenic Differentiation ◽  
Muscle Growth ◽  
Backfat Thickness ◽  
Meat Production ◽  
Nucleotide Polymorphisms ◽  
Production Traits ◽  
Muscle Area ◽  
Single Nucleotide ◽  
Pig Breeds

lncMGPF is a novel positive regulator of myogenic differentiation, muscle growth and regeneration in mouse, pig, and human. But whether natural mutations within lncMGPF gene regulate animal meat production traits is unclear. In this study, ten single nucleotide polymorphisms (SNPs) of pig lncMGPF (plncMGPF) gene were identified among commercial pig breeds and Chinese local pig breeds. These SNPs are highly linked and constructed into multiple haplotypes, and haplotype ATTCATGTTC (H1) mainly exists in commercial pig breeds while haplotype GCCTGCACCT (H3) is more frequent in Chinese local pig breeds. Association analysis indicated that all SNPs are significantly associated with the backfat thickness and loin muscle area (P &lt; 0.05), respectively, and homologous H1 individuals have higher loin muscle area and lower backfat thickness than H3 pigs. Bioinformatics and functional analysis showed that haplotype H1 has a longer half-life and more stable RNA secondary structure than haplotype H3. plncMGPF haplotype H1 has stronger effects on pig primary myogenic progenitor cells differentiation and muscle growth than haplotype H3. Further experiments showed that two SNPs (rs81403974 and rs325492834) function together to confer plncMGPF stability and function. Our observation suggested that the SNPs in lncMGPF can change the RNA stabilities and lncMGPF function, thereby affecting the porcine meat production traits.

scholarly journals BROWN PLUMAGE JAPANESE QUAILS ARE THE BEST BIRDS POPULATION FOR THE LARGE-SCALE EGG PRODUCTION

2021 ◽  
Vol 52 (2) ◽  
pp. 309-314
Author(s):  
D. A. Ali ◽  
F. R. Al-Khafajy ◽  
M. B. S. Al-Shuhaib
Keyword(s):  
Egg Production ◽  
Large Scale ◽  
Growth Traits ◽  
Meat Production ◽  
Production Traits ◽  
Feed Conversion ◽  
Black Line ◽  
White Line ◽  
Black And White ◽  
Japanese Quails

This study was conducted to investigate the effect of the line of Japanese quails on several production traits of 800 hatched eggs in three populations differ in plumage color, Brown-line (n = 300), Black-line (n = 220), and White-line (n = 280). Variables growth traits were examined on weekly intervals, namely live body weight (LBW), egg weight (EW), egg numbers (EN), hen day production (HD%), and feed conversion ratio (FCR) in the entire investigated period. Results indicated the presence of a significant effect of the studied lines on the majority of investigated traits. Concerning LBW, Black-line showed higher values than Brown and White lines respectively, in the last three weeks of measurements. Concerning EW, no obvious superiority was recorded for each investigated line except for the 10th week, in which significant (P<0.01) higher values of Brown-line were observed over the other two lines. Meanwhile, Brown-line had exhibited significantly (P<0.01) higher EN and HD% values over Black and White lines, respectively. On the contrary, FCR in White-line scored higher values starting from the 10th week to the end of the experiment (12th week) than Black and Brown lines, respectively. In conclusion, this study demonstrated the obvious superiority of the Brown-line over Black and White lines in the egg production traits measured. Since Black-line showed relatively higher values in LBW, we may suggest it for meat production. Meanwhile, Brown-line is the best-suited population for egg production. The observed data can be used by breeders in the large-scale egg production purposes of Japanese quails.

scholarly journals Function of the Porcine TRPC1 Gene in Myogenesis and Muscle Growth

Cells ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 147
Author(s):  
Yu Fu ◽  
Peng Shang ◽  
Bo Zhang ◽  
Xiaolong Tian ◽  
Ruixue Nie ◽  
...  
Keyword(s):  
Transient Receptor Potential ◽  
Growth Traits ◽  
Expression Profiles ◽  
Muscle Growth ◽  
Receptor Potential ◽  
Transient Receptor Potential Channel ◽  
Nucleotide Polymorphisms ◽  
Pig Breeds ◽  
Muscle Tissues ◽  
Transient Receptor

In animals, muscle growth is a quantitative trait controlled by multiple genes. Previously, we showed that the transient receptor potential channel 1 (TRPC1) gene was differentially expressed in muscle tissues between pig breeds with divergent growth traits base on RNA-seq. Here, we characterized TRPC1 expression profiles in different tissues and pig breeds and showed that TRPC1 was highly expressed in the muscle. We found two single nucleotide polymorphisms (SNPs) (C-1763T and C-1604T) in TRPC1 that could affect the promoter region activity and regulate pig growth rate. Functionally, we used RNAi and overexpression to illustrate that TRPC1 promotes myoblast proliferation, migration, differentiation, fusion, and muscle hypertrophy while inhibiting muscle degradation. These processes may be mediated by the activation of Wnt signaling pathways. Altogether, our results revealed that TRPC1 might promote muscle growth and development and plays a key role in Wnt-mediated myogenesis.

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