scholarly journals Optimization of extraction conditions for polyphenols from the stem bark of Funtumia elastica (Funtum) utilizing response surface methodology

2021 ◽  
Vol 4 ◽  
pp. 46
Author(s):  
Theophilus Fadjare Frempong ◽  
Nathaniel Owusu Boadi ◽  
Mercy Badu
Keyword(s):  
Phenolic Compounds ◽  
Response Surface ◽  
Response Surface Method ◽  
Phenolic Content ◽  
Stem Bark ◽  
Total Phenolic ◽  
Liquid Ratio ◽  
Surface Method ◽  
Solid Liquid ◽  
The Impact

Background: The recovery of phenolic compounds is seen as an arduous task because phenolic compounds are available as free aglycones, as sugar or ester conjugates, or as polymers with several monomeric components. Furthermore, phenolic compounds do not disperse evenly and may be connected to cell walls, carbohydrates, or proteins. This study looks at the optimization of factors that affect the efficiency for the extraction of phenolic compounds from the stem-bark of Funtumia elastica. Methods: Five independent variables (solvent concentration, time, the temperature, solid-liquid ratio, and pH) of the extraction process were selected. Single factor analysis as well as the response surface method was used to evaluate the impact of the selected factors on the total phenolic content. The effect of the extraction factors on the phenolic content was statistically significant (p <0.05). For the response surface method, a five/factor, five/level central composite design used, and a fitted second-order polynomial regression model equation was used to show how the extraction parameters affected the total phenolic recovery. Results: The predicted value (R² of 0.5917) agreed with the adjusted value (R² of 0.7707). The residuals for response predictions were less than 5%. The optimal factors for the extraction were ethanol concentration of 75.99% v/v, extraction time of 193.86 minutes, temperature of 63.66°C, pH of 5.62, and solid-liquid ratio of 1:21.12 g/mL. Actual overall content of the phenolic compounds was validated at 82.83 ± 3.335 mg gallic acid equivalent (GAE) /g weight of extract, which agreed with the predicted response of 89.467 mg GAE/g of the dried extract under the optimal factors. Conclusions: The rich phenolic content of stem-bark of Funtumia elastica points to its potential as a functional medicinal product to alleviate diseases caused by oxidative stress such as asthma, breathing disorders, inflammation, and cardiovascular diseases.

scholarly journals Modeling of Total Phenolic contents in Various Tea samples by Experimental Design Methods

2018 ◽  
Vol 16 (1) ◽  
pp. 738-744
Author(s):  
Nuraniye Eruygur ◽  
Nazire Gulsah Kutuk Dincel ◽  
Nursah Kutuk
Keyword(s):  
Phenolic Compounds ◽  
Experimental Design ◽  
Green Tea ◽  
Total Phenolic ◽  
Phenolic Substance ◽  
Extraction Temperature ◽  
Liquid Ratio ◽  
Polyphenol Content ◽  
Positive Effects ◽  
Solid Liquid

AbstractTea, from the old ages to the day, is widely consumed both for enjoyment and health care due to its positive effects. The consumption of these products is increasing day by day as a result of the clear presentation of the fact that tea contains high amount of antioxidant substances (such as phenolic compounds), which is important in prevention and treatment of diseases. Tea beverage is a very important source of polyphenols. In this study, phenolic content and antioxidant capacity of different tea species were calculated by modeling with experimental design method. In the experimental part, polyphenol content was determined using the Folin-Ciocalteu method. The total amount of phenolic substance content was examined by Box-Behnken design and response surface method on black tea, green tea and white tea on different extraction temperature, extraction time and solid / liquid ratio. Solid / liquid ratio was found to be the most important parameter in terms of polyphenol content extraction from different tea samples. The highest polyphenol amount (411.762 mg gallic acid / mL) was found in green tea. To the best of our knowledge, this is the first data presenting comparatively study the effect of extraction condition on amounts of phenolic compounds from different tea samples.

scholarly journals Processing of Herbal Tea from Roselle (Hibiscus sabdariffa L.): Effects of Drying Temperature and Brewing Conditions on Total Soluble Solid, Phenolic Content, Antioxidant Capacity and Sensory Quality

Beverages ◽  
2020 ◽  
Vol 6 (1) ◽  
pp. 2
Author(s):  
Quang Vinh Nguyen ◽  
Hoang Van Chuyen
Keyword(s):  
Antioxidant Capacity ◽  
Sensory Quality ◽  
Phenolic Content ◽  
Hot Water ◽  
Total Phenolic ◽  
Hibiscus Sabdariffa ◽  
Liquid Ratio ◽  
Herbal Tea ◽  
Soluble Solid ◽  
Solid Liquid

Roselle (Hibiscus sabdariffa L.) is an annual shrub popularly grown in tropical and subtropical areas. Although Roselle fruit has been used for a long time as a herbal tea due to its high content of bioactive compounds like phenolic acids and anthocyanins, the studies on the effects of the drying process and brewing conditions on the content of beneficial components and bioactivities of Roselle tea is limited. In this study, the influence of drying temperature on the retention of total phenolic content (TPC) and antioxidant capacity (AC) of the dried Roselle and the effects of brewing conditions including water temperature, liquid-solid ratio and brewing time on total soluble solid (TSS) content, total phenolic content, and antioxidant capacity of Roselle tea were investigated. The drying at 80 °C produced the dried Roselle with the highest retention of TPC (25.196 mg GAE/g) and AC (IC50 of 2.2 mg/mL for 2,2-diphenyl-1-picrylhydrazyl (DPPH) inhibition) and the highest sensory quality compared to the drying at other temperatures. The brewing process using hot water at 90 °C with the solid-liquid ratio of 1:10 (g/mL) for 30 min resulted in the highest TSS content (5.4 oBx), TPC (12.7 mg GAE/g dried Roselle) and AC (73.3% DPPH inhibition) of the Roselle tea. Thus, the drying at 80 °C combined with the brewing of dried Roselle for 30 min using 90 °C hot water with the solid-liquid ratio of 1:10 (g/mL) are recommended to produce Roselle tea with the highest content of beneficial ingredients.

Determination of optimal extraction conditions for phenolic compounds from Pistacia atlantica leaves using the response surface methodology

2016 ◽  
Vol 8 (31) ◽  
pp. 6107-6114 ◽  
Author(s):  
Ziyad Ben Ahmed ◽  
Mohamed Yousfi ◽  
Johan Viaene ◽  
Bieke Dejaegher ◽  
Kristiaan Demeyer ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Phenolic Compounds ◽  
Response Surface ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Total Phenolic ◽  
Box Behnken Design ◽  
Pistacia Atlantica

Response surface methodology in combination with a Box–Behnken design was performed to optimize the extraction conditions, resulting in a maximum total phenolic content yield from Pistacia atlantica leaves.

scholarly journals Ultrasound-Assisted Extraction of Polyphenols from Crude Pollen

Antioxidants ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 322 ◽  
Author(s):  
Mircea Oroian ◽  
Florin Ursachi ◽  
Florina Dranca
Keyword(s):  
Extraction Efficiency ◽  
Phenolic Content ◽  
Extraction Yield ◽  
Total Phenolic ◽  
Optimum Conditions ◽  
Liquid Ratio ◽  
Ultrasound Assisted Extraction ◽  
Assisted Extraction ◽  
Ultrasonic Process ◽  
Solid Liquid

The aim of this study was to evaluate the extraction efficiency of polyphenols from crude pollen by an ultrasonic process. Prior to the polyphenols extraction, the crude pollen was defatted. The extraction from defatted pollen was carried out by varying four extraction parameters: ultrasonic amplitude (20%, 60% and 100%), solid/liquid ratio (10 g/L, 20 g/L and 30 g/L), temperature (35, 50 and 65 °C) and time (10, 20 and 30 min). The extracts were analyzed in terms of extraction yield (%), total phenolic content (TPC) and total flavones content (TFC). The extracted oil was analyzed in terms of fatty acids composition; myristic acid (159.1 µg × g−1) and cis-14-pentadecenoic acid (106.6 µg·g−1) were found in the highest amount in the pollen oil. The optimum conditions of extraction were determined and were, as follows: 100% amplitude of ultrasonic treatment, 30 g/L solid/liquid ratio, 40.85 °C and 14.30 min, which led to the extraction of 366.1 mg GAE/L of TPC and 592.2 mg QE/g of TFC, and also to an extraction yield of 1.92%.

scholarly journals Impact of Brewing Methods on Total Phenolic Content (TPC) in Various Types of Coffee

Molecules ◽  
2020 ◽  
Vol 25 (22) ◽  
pp. 5274
Author(s):  
Ewa Olechno ◽  
Anna Puścion-Jakubik ◽  
Renata Markiewicz-Żukowska ◽  
Katarzyna Socha
Keyword(s):  
Phenolic Compounds ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Hot Water ◽  
Effect Of Temperature ◽  
Total Phenolic ◽  
Water Type ◽  
Preparation Methods ◽  
The Impact ◽  
Coffee Machine

Coffee is a widely consumed beverage, both in Europe, where its consumption is highest, and on other continents. It provides many compounds, including phenolic compounds. The aim of the study was to assess the effect of various brewing methods on the total phenolic content (TPC) in the infusion. Research material comprised commercially available coffees: Instant Arabica and Robusta, freshly ground Arabica and Robusta (immediately prior to the analysis), ground Arabica and Robusta, decaffeinated Arabica, and green Arabica and Robusta. The following preparation methods were used: Pouring hot water over coffee grounds or instant coffee, preparing coffee in a percolator and using a coffee machine. Additional variables which were employed were water temperature (90 or 100 °C) and its type (filtered or unfiltered). In order to determine the impact of examined factors, 225 infusion were prepared. Total phenolic content was determined by the spectrophotometric method using the Folin-Ciocalteu reagent and the obtained results were expressed in mg gallic acid (GAE) per 100 g of brewed coffee. The highest value was obtained for 100% Arabica ground coffee prepared in a coffee percolator using unfiltered water at a temperature of 100 °C: 657.3 ± 23 mg GAE/100 g of infusion. High values were also observed for infusions prepared in a coffee machine, where the highest TPC value was 363.8 ± 28 mg GAE/100 g for ground Arabica. In turn, the lowest TPC was obtained for Arabica green coffee in opaque packaging, brewed with filtered water at a temperature of 100 °C: 19.5 ± 1 mg GAE/100 g of infusion. No significant effect of temperature and water type on the TPC within one type of coffee was observed. Due to its high content of phenolic compounds, Arabica coffee brewed in a coffee percolator should be the most popular choice for coffee drinkers.

scholarly journals ASSESSMENT OF THE IMPACT OF GEOMECHANICAL PARAMETERS VARIABILITY ON UNDERGROUND EXCAVATIONS STABILITY USING RESPONSE SURFACE METHOD

2013 ◽  
Vol 35 (1) ◽  
pp. 183-194 ◽  
Author(s):  
Witold Pytel ◽  
Joanna Świtoń
Keyword(s):  
Rock Mass ◽  
Response Surface ◽  
Response Surface Method ◽  
Safety Issue ◽  
Mineral Deposit ◽  
Mining Operations ◽  
Mean Values ◽  
Surface Method ◽  
Geomechanical Parameters ◽  
The Impact

Abstract Recognition of properties of the rock mass surrounding a mineral deposit is particularly important for the mining operations at greater depths. Since the rock mass is usually not homogeneous, and its parameters have characteristics of randomness, underground workings safety issue should always be analysed taking into account the dispersion of the values of these parameters around their mean values. In order to assess the impact of geotechnical parameters uncertainty on the excavation stability one uses the appropriate statistical approach. In this paper, by analysing successive combinations of geomechanical parameters of the rock in the measured range, we examined the effect of their variability on risk of underground excavation instability using response surface method.

scholarly journals Optimization of the extraction of phenolic compounds and antioxidant activity from the roots of Waltheria ovata using the response surface methodology

Food Research ◽  
2020 ◽  
Vol 4 (6) ◽  
pp. 2095-2102
Author(s):  
O. Herrera-Calderon ◽  
R. Vega
Keyword(s):  
Antioxidant Activity ◽  
Response Surface Methodology ◽  
Phenolic Compounds ◽  
Response Surface ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Natural Antioxidants ◽  
Total Phenolic ◽  
Dpph Assay ◽  
Sample Ratio

Waltheria ovata is a medicinal plant belonging to the Sterculiaceae genus. Natural products of Waltheria ovata could be used in the food industry as natural antioxidants due to its high content of polyphenols according to the literature. The main objective in this research was to optimize the extraction of phenolic compounds and the antioxidant activity from Waltheria ovata roots using response surface methodology (RSM). The total phenolic content in different extracts was determined by spectrophotometric method (Folin-Ciocalteu reagent) and the antioxidant activity by using DPPH assay. To optimize the conditions for total phenolic content and antioxidant activity were used three independent variables: solvent/sample ratio (1:10, 1:20 and 1:30 g/mL), temperature (40, 50, and 60°C) and time (40, 50 and 60 mins). The results showed that total phenolic content and antioxidant activity in the experiments ranged from 8.7 to 12.1 mg GAE/g and 76.1% to 96.7%, respectively. The coefficients of determination (R2 values) for phenolic content and antioxidant activity were 0.86 and 0.91, respectively. Under the optimum conditions of 1:20 g/mL, 60°C and 55 mins of extraction, the values for total phenolic content and antioxidant activity were 0.448±0.02 mg GAE/g and 87.00±2.0%, respectively. These data showed that the experimental responses were reasonably close to the predicted responses (0.444 mg GAE/g and 84.67%). Therefore, the results showed that Waltheria ovata can be used as antioxidant in foods.

scholarly journals Ultrasound-Assisted Extraction of Total Phenolic Compounds fromInula helenium

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Jin Wang ◽  
Yong-Ming Zhao ◽  
Ya-Ting Tian ◽  
Chun-Lin Yan ◽  
Chun-Yan Guo
Keyword(s):  
Phenolic Compounds ◽  
Ethanol Concentration ◽  
Total Phenolic ◽  
Total Phenolic Compounds ◽  
Liquid Ratio ◽  
Ultrasound Assisted Extraction ◽  
Assisted Extraction ◽  
Ultrasonic Time ◽  
Ultrasound Assisted ◽  
Solid Liquid

Ultrasound-assisted extraction (UAE) of phenolic compounds fromInula heleniumwas studied. Effects of ethanol concentration, ultrasonic time, solid-liquid ratio, and number of extractions were investigated. An orthogonal array was constructed to optimize UAE process. The optimized extraction conditions were as follows: ethanol concentration, 30%; solid-liquid ratio, 1 : 20; number of extractions, 2 times; extraction time, 30 min. Under the optimal conditions, the yield of total phenolic compounds and chlorogenic acid was6.13±0.58and1.32±0.17 mg/g, respectively. The results showed that high amounts of phenolic compounds can be extracted fromI. heleniumby ultrasound-assisted extraction technology.

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