Research Progress on the Identification and Pharmacological Activity of the Active Components of the Rhododendron Species

2021 ◽  
Vol 18 (3) ◽  
pp. 543-565
Author(s):  
Myong- Hun Han ◽  
Kwang Yong Kim
Keyword(s):  
Traditional Medicine ◽  
Pharmacological Activity ◽  
Present Review ◽  
Research Progress ◽  
Pharmacological Properties ◽  
Medicine Use ◽  
Active Components ◽  
Wide Range ◽  
History Of ◽  
Phytochemical Compounds

Rhododendron is one of the plants with the broadest spectrum species, the most extended history of traditional medicine use, and the wide range of pharmacological properties. In 2013, a report was published to summarize the studies reported from 1898 to 2012. Many phytochemical compounds and their various treatment effects of over 40 Rhododendron species were mentioned in the present review. This review aims to evaluate the newly discovered and observed phytochemical compounds in recent years and their activities in some Rhododendron species.

A Brief Review on the Development of Novel Potentially Active Azetidin-2-ones Against Cancer

2020 ◽  
Vol 24 (5) ◽  
pp. 473-486 ◽  
Author(s):  
Ligia S. da Silveira Pinto ◽  
Thatyana R. Alves Vasconcelos ◽  
Claudia Regina B. Gomes ◽  
Marcus Vinícius N. de Souza
Keyword(s):  
Side Effects ◽  
Anticancer Agents ◽  
Heterocyclic Compounds ◽  
Biological Activities ◽  
Present Review ◽  
Pharmacological Properties ◽  
Important Group ◽  
Wide Range ◽  
Anti Inflammatory

Azetidin-2-ones (β-lactams) and its derivatives are an important group of heterocyclic compounds that exhibit a wide range of pharmacological properties such as antibacterial, anticancer, anti-diabetic, anti-inflammatory and anticonvulsant. Efforts have been made over the years to develop novel congeners with superior biological activities and minimal potential for undesirable side effects. The present review aimed to highlight some recent discoveries (2013-2019) on the development of novel azetidin-2-one-based compounds as potential anticancer agents.

Review on pharmacological and phytochemical prospects of traditional medicinal plant: Persicaria hydropiper (Smartweed)

2021 ◽  
Vol 21 ◽  
Author(s):  
Abdul Nasir ◽  
Atif Ali Khan Khalil ◽  
Muhammad Zeeshan Bhatti ◽  
Ashfaq Ur Rehman ◽  
Jiayi Li ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Traditional Medicine ◽  
Northern Hemisphere ◽  
Biological Activities ◽  
Folk Medicine ◽  
Present Review ◽  
Polygonum Hydropiper ◽  
Wide Range ◽  
Pharmacological Data ◽  
Different Parts

: Persicaria hydropiper (L.) Delarbre (family Polygonacea), commonly known as Polygonum hydropiper, is a popular medicinal plant used in traditional medicine. The plant is indigenous to the tropical northern hemisphere and temperate zone including China, Bangladesh, India, and Japan. The plant is used in folk medicine for numerous ailments such as hemorrhoids, antifertility, diarrhea, and dyspepsia. Its medicinal usage in Unani, Ayurveda, Siddha, and other traditional medicine is well-recognized. So far, a wide range of active phytochemicals of this plant has been identified, such as flavonoids, sulphated flavonoids, terpenoids, anthraquinones, steroids, coumarin, simple phenolics, and others. Pharmacological data reported in the literature suggest that various parts of P. hydropiper exhibit antimicrobial, antioxidant, hypoglycemic, antidepressant, cardioprotective, hepatoprotective, anticancer, and antifertility effects. The present review aim is to compile the coherently document research on the phytochemical, pharmacological, and biological activities of P. hydropiper from different parts of the globe.

Asperugo Procumbens: a Review of Botany, Traditional Uses, Phytochemistry and Pharmacology

2021 ◽  
Vol 15 (10) ◽  
pp. 3092-3095
Author(s):  
Grzegorz Łazarski
Keyword(s):  
Fatty Acids ◽  
Traditional Medicine ◽  
Linolenic Acid ◽  
Pharmacological Study ◽  
Stearidonic Acid ◽  
Pharmacological Properties ◽  
Omega 3 ◽  
Comprehensive Overview ◽  
Traditional Uses ◽  
Wide Range

Asperugo procumbens is a medicinal plant widely distributed in the world, which is commonly used in the traditional medicine of the Middle East, while currently overlooked in European pharmacopoeias. The aim of the study is to present a comprehensive overview of A. procumbens in botany, traditional medicine, phytochemistry and pharmacology according to the up-to-date data. Scientific literature on the species was collected based on publicly available databases such as: PubMed, Web of Science, Scopus, Google, Google Scholar as well as monographs and PhD theses. In traditional medicine the aerial part of A. procumbens is used for treatment of skin infections, herpes, liver and respiratory tract diseases, to strengthen the heart and the nervous system, and others. Contemporary studies on the pharmacological activity of A. procumbens revealed that it exhibits a wide range of pharmacological properties, including antioxidant, antidepressant, sedative-hypnotic, antibacterial, as well as chemopreventive and antihypertensive properties. Despite many proven medicinal properties, the species does not have a developed phytochemical profile and its chemical composition is very poorly understood. The species is known to contain tannins, flavonoids and phenolics. Only the content of fatty acids is recognised in detail. The species is a good source of omega-3 fatty acids – stearidonic acid (SDA), α-linolenic acid (ALA), and omega-6 fatty acid – γ-linolenic acid (GLA). This article, based on the available literature, highlights the traditional uses, phytochemistry and pharmacological properties of A. procumbens, which may provide a foundation for further pharmacological study as well as clinical application of the species. Keywords: Asperugo procumbens, German madwort, Boraginaceae, traditional uses

Progress in Synthesis and Bioactivity Evaluation of Pyrazoloquinazolines

2020 ◽  
Vol 17 (2) ◽  
pp. 104-113
Author(s):  
Hui Zhao ◽  
Xiaoxia Hu ◽  
Yue Zhang ◽  
Chunlei Tang ◽  
Bainian Feng
Keyword(s):  
Present Article ◽  
Research Progress ◽  
Synthesis Methods ◽  
Pharmacological Properties ◽  
Recent Advances ◽  
Wide Range ◽  
Significant Interest ◽  
Antiviral Activities ◽  
Anti Inflammatory ◽  
Derivatives Of

Background: This paper reviews the research progress of pyrazoloquinazolines which widely used in the field of medicine and pesticide in recent years. Five types of pyrazoloquinazolines are introduced: pyrazolo [4,3-h]quinazolines, pyrazolo[1,5-c]quinazolines, pyrazolo[4,3-f]quinazolines, pyrazolo[1,5-a] quinazolines , pyrazolo[1,5-b]quinazolines, and their new progress in the synthesis methods and treatment of diseases. Methodology: The derivatives of pyrazoloquinazolines exhibit a wide range of pharmacological properties such as antibacterial, anticancer, antioxidants, anti-inflammatory, anti-diabetic, antiviral activities. Consequently, their syntheses have attracted significant interest. Various methodologies have been developed for the synthesis and functionalization of these class of compounds. Conclusion: In the present article, the relevant and recent advances in the field will be briefly covered.

scholarly journals Pemanfaatan Tumbuhan Liar Bandotan (Ageratum conyzoides L.) sebagai Obat Tradisional dan Aktivitas Farmakologinya

BIOSCIENTIAE ◽  
2021 ◽  
Vol 18 (1) ◽  
pp. 28
Author(s):  
Raudatul Hilaliyah
Keyword(s):  
Herbal Medicine ◽  
South America ◽  
Essential Oils ◽  
Traditional Medicine ◽  
Pharmacological Activity ◽  
Ageratum Conyzoides ◽  
Phytochemical Compounds ◽  
Anti Inflammatory ◽  
Hiv Aids

Bandotan (Ageratum conyzoides L.) is a plant belonging to the Asteracea family. This plant is widely used as medicine in various countries such as Africa, Asia and South America. Bandotan is used as medicine because it contains useful phytochemical compounds such as terpenoids, alkaloids, essential oils, saponins and phenolics. Some of the pharmalogical activities on bandotan include antibacterial, anti-inflammatory, antioxidant, and antidiabetic. Several studies have shown that bandotan can be used as a treatment for fever, rheumatism, headaches, stomach aches, medicine for pneumonia, drugs for diarhea, diabetes, and HIV/AIDS. The article review is expected to provide information about the use of bandotan as a traditional medicine or herbal medicine and its pharmacological activity.

scholarly journals New Insights Into the Biosynthesis of Typical Bioactive Components in the Traditional Chinese Medicinal Fungus Cordyceps militaris

2021 ◽  
Vol 9 ◽  
Author(s):  
Xiuyun Wu ◽  
Tao Wu ◽  
Ailin Huang ◽  
Yuanyuan Shen ◽  
Xuanyu Zhang ◽  
...  
Keyword(s):  
Low Cost ◽  
Gene Clusters ◽  
Cordyceps Militaris ◽  
Research Progress ◽  
Microbial Cell Factories ◽  
Medicinal Fungus ◽  
Cell Factories ◽  
Wide Range ◽  
History Of ◽  
Bioactive Ingredients

Cordyceps militaris, a traditional medicinal ingredient with a long history of application in China, is regarded as a high-value fungus due to its production of various bioactive ingredients with a wide range of pharmacological effects in clinical treatment. Several typical bioactive ingredients, such as cordycepin, D-mannitol, cordyceps polysaccharides, and N6-(2-hydroxyethyl)-adenosine (HEA), have received increasing attention due to their antitumor, antioxidant, antidiabetic, radioprotective, antiviral and immunomodulatory activities. Here, we systematically sorted out the latest research progress on the chemical characteristics, biosynthetic gene clusters and pathways of these four typical bioactive ingredients. This summary will lay a foundation for obtaining low-cost and high-quality bioactive ingredients in large amounts using microbial cell factories in the future.

scholarly journals A synthesis and review of medicinal uses, phytochemistry and pharmacological properties of Schef৒lera umbellifera (Sond.) Baill. (Ar aliaceae )

2020 ◽  
Vol 11 (4) ◽  
pp. 5460-5466
Author(s):  
Alfred Maroyi
Keyword(s):  
Traditional Medicine ◽  
Pharmacological Properties ◽  
Journal Articles ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Documented Information ◽  
Phytochemical Compounds ◽  
Cytotoxicity Activities ◽  
The University ◽  
Online Sources

Schefflera umbellifera (Sond.) Baill. is an evergreen tree widely used as traditional medicine throughout its distributional range in southern Africa. Schefflera umbellifera is indigenous to Eswatini, Malawi, Mozambique, South Africa and Zimbabwe. This study was aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of S. umbellifera. Documented information on medicinal uses, phytochemical and pharmacological properties of S. umbellifera was collected from several online sources such as Scopus, Google Scholar, PubMed, Francis and Taylor and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the University library. This study revealed that the bark, leaf and root decoction or infusion of S. umbellifera are mainly used as diuretic, laxative, colic and protective charm, and traditional medicine for stomach ulcers, weaning infants, insanity, inflammation, rheumatism and malaria. Phytochemical compounds identified from the species include 3-hydroxy-20(29)-lupen-28-ol, 7-hydroxy-6-methoxycoumarin, betulin, ent-kaur-16-en-19-oic acid and oleanolic acid. Pharmacological research revealed that S. umbellifera extracts and compounds isolated from the species have antibacterial, anti-HIV, anti-inflammatory, antimalarial, antiprotozoal, larvicidal and cytotoxicity activities. Schefflera umbellifera should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.

A wide range of pharmacological properties of melatonin

2021 ◽  
Vol 19 (1) ◽  
pp. 103-106
Author(s):  
Eduard B. Arushanian ◽  
Stanislav S. Naumov
Keyword(s):  
Pineal Gland ◽  
Pharmacological Activity ◽  
Experimental Work ◽  
Pharmacological Properties ◽  
Wide Range ◽  
Anti Inflammatory

The pineal gland hormone melatonin has various pharmacological activity. In experimental work, he revealed anti-anxiety, antidepressant, neuroprotective, anti-pain and anti-inflammatory properties.

scholarly journals Review of Pharmacological Properties, Phytochemistry and Medicinal uses of Volkameria glabra -

2020 ◽  
Vol 10 (5) ◽  
pp. 264-273
Author(s):  
Alfred Maroyi
Keyword(s):  
Traditional Medicine ◽  
Pharmacological Properties ◽  
Ethnoveterinary Medicine ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Documented Information ◽  
Phytochemical Compounds ◽  
Cytotoxicity Activities ◽  
Immune Booster ◽  
The University

Volkameria glabra (E. Mey.) Mabb. & Y.W. Yuan is a deciduous shrub or a small tree widely used as traditional medicine throughout its distributional range in tropical Africa. This study is aimed at providing a critical review of pharmacological properties, phytochemistry, and medicinal uses of V. glabra. Documented information on pharmacological properties, phytochemistry and medicinal uses of V. glabra was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. This study revealed that the bark, leaf and root infusion and/or decoction of V. glabra are mainly used as immune booster, protective charm, anthelmintic and ethnoveterinary medicine, and traditional medicine for convulsions, fractured bones, fever, wounds, gastro-intestinal problems, snake bite and respiratory diseases. Phytochemical compounds identified from the species include aliphatic glycosides, anthraquinones, cardiac glycosides, flavonoids, iridoid, phenols, saponins, steroids, tannins and triterpenoids. The V. glabra and compounds isolated from the species exhibited acaricidal, anthelmintic, antibacterial, antifungal, antimycobacterial, anti-collagenase, antidiabetic, anti-elastase, anti-inflammatory, antileishmanial, antioxidant, antiplasmodial, antipyretic, cholinesterase enzyme inhibition, immune-stimulant and cytotoxicity activities. Volkameria glabra should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.

scholarly journals ETHNOBOTANICAL AND PHYTOPHARMACOLOGICAL REVIEW OF PISONIA ALBA SPAN

2017 ◽  
Vol 10 (5) ◽  
pp. 69
Author(s):  
Tamizhazhagan V ◽  
K Pugazhendy
Keyword(s):  
Traditional Medicine ◽  
Chronic Diseases ◽  
Pharmacological Properties ◽  
Medicine Use ◽  
Long Period ◽  
Toxicity Studies ◽  
Whole Plant ◽  
Novel Drug ◽  
Anti Inflammation

Pisonia alba is used for the long period in various chronic diseases in traditional medicine use. To desire of this review is to search literature for the pharmacological properties toxicity studies, pharmacology studies and phytochemical exploration of anti-inflammation, antidiabetic studies,antioxidant, etc., and the amassed data may be helpful for the researchers to attention on the significance areas of research yet to be revealed. Widespread information about the plant has been together from various books, journals and ayurvedic classical texts, etc. Researcher and pharmacologist and Ayurveda treatment may be helpful security of the whole plant was settled in the criticism.Keywords: Pisonia alba, Antioxidant, Ayurvedic, Novel drug, Ethno botanical.  

Sign in / Sign up

Export Citation Format

Share Document