Evaluation of the Nutritional Status of Chronic Haemodialysis Patients at Nouakchott National Hospital (Mauritania): Prevalence and Risk Factors for Undernutrition

Abstract Background This study aimed to investigate the connection between malnutrition evaluated by the Controlling Nutritional Status (CONUT) score and the risk of contrast-associated acute kidney injury (CA-AKI) in elderly patients who underwent percutaneous coronary intervention (PCI). Methods A total of 1308 patients aged over 75 years undergoing PCI was included. Based on the CONUT score, patients were assigned to normal (0–1), mild malnutrition (2–4), moderate-severe malnutrition group (≥ 5). The primary outcome was CA-AKI (an absolute increase in ≥ 0.3 mg/dL or ≥ 50% relative serum creatinine increase 48 h after contrast medium exposure). Results Overall, the incidence of CA-AKI in normal, mild, moderate-severe malnutrition group was 10.8%, 11.0%, and 27.2%, respectively (p < 0.01). Compared with moderate-severe malnutrition group, the normal group and the mild malnutrition group showed significant lower risk of CA-AKI in models adjusting for risk factors for CA-AKI and variables in univariate analysis (odds ratio [OR] = 0.48, 95% confidence interval [CI]: 0.26–0.89, p = 0.02; OR = 0.46, 95%CI: 0.26–0.82, p = 0.009, respectively). Furthermore, the relationship were consistent across the subgroups classified by risk factors for CA-AKI except anemia. The risk of CA-AKI related with CONUT score was stronger in patients with anemia. (overall interaction p by CONUT score = 0.012). Conclusion Moderate-severe malnutrition is associated with higher risk of CA-AKI in elderly patients undergoing PCI.

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Revisiting Konzo Risk Factors in Three Areas Differently Affected by Spastic Paraparesis in Eastern Democratic Republic of the Congo Discloses a Prominent Role of the Nutritional Status—A Comparative Cross-Sectional Study

Nutrients ◽

10.3390/nu13082628 ◽

2021 ◽

Vol 13 (8) ◽

pp. 2628

Author(s):

Marius Baguma ◽

Espoir Bwenge Malembaka ◽

Esto Bahizire ◽

Germain Zabaday Mudumbi ◽

Dieudonné Bahati Shamamba ◽

...

Keyword(s):

Risk Factors ◽

Nutritional Status ◽

Democratic Republic ◽

Cross Sectional Study ◽

Sectional Study ◽

Cyanide Poisoning ◽

Cross Sectional ◽

High Prevalence ◽

Republic Of The Congo

This comparative cross-sectional study aimed to better understand the respective contributions of protein malnutrition and cassava-derived cyanide poisoning in the development of konzo. We compared data on nutritional status and cyanide exposure of school-age adolescent konzo-diseased patients to those of non-konzo subjects of similar age from three areas in the Eastern Democratic Republic of the Congo. Our results show that konzo patients had a high prevalence of both wasting (54.5%) and stunting (72.7%), as well as of cyanide poisoning (81.8%). Controls from Burhinyi and those from Idjwi showed a similar profile with a low prevalence of wasting (3.3% and 6.5%, respectively) and intermediate prevalence of stunting (26.7% and 23.9%, respectively). They both had a high prevalence of cyanide poisoning (50.0% and 63.0%, respectively), similar to konzo-patients. On the other hand, controls from Bukavu showed the lowest prevalence of both risk factors, namely chronic malnutrition (12.1%) and cyanide poisoning (27.6%). In conclusion, cassava-derived cyanide poisoning does not necessarily coexist with konzo outbreaks. The only factor differentiating konzo patients from healthy individuals exposed to cyanide poisoning appeared to be their worse nutritional status. This further suggests that, besides the known role of cyanide poisoning in the pathogenesis of konzo, malnutrition may be a key factor for the disease occurrence.

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SAT0047 RISK FACTORS FOR THE POSTOPERATIVE DELAYED WOUND HEALING IN PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH A BIOLOGICAL AGENT

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2020-eular.3424 ◽

2020 ◽

Vol 79 (Suppl 1) ◽

pp. 954.3-954

Author(s):

S. Okita ◽

H. Ishikawa ◽

A. Abe ◽

S. Ito ◽

A. Murasawa ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Risk Factors ◽

Wound Healing ◽

Retrospective Study ◽

Nutritional Status ◽

Disease Activity ◽

Disease Duration ◽

Foot And Ankle ◽

Delayed Wound Healing ◽

Chugai Pharmaceutical

Background:It has been suggested that perioperative use of biological disease-modifying anti-rheumatic drugs (bDMARDs) in rheumatoid arthritis (RA) patients carries risks for the surgical-site infection and the delayed wound healing (DWH); however, the risk of DWH with perioperative use of bDMARDs has not reached a general consensus.Objectives:This retrospective study aimed to investigate the risk factors associated with DWH after orthopedic surgery in RA patients treated with bDMARDs.Methods:We reviewed medical records of 277 orthopedic procedures for 188 RA patients treated with bDMARDs between from 2014 to 2017 in Niigata Rheumatic Center. As preoperative nutritional status assessment, we evaluated body mass index (BMI), prognostic nutritional index (PNI), and CONtrolling NUTritional status (CONUT). In addition, we evaluated DAS28-CRP, DAS28-ESR, face scale for pain, global health (GH), and Health Assessment Questionnaire-Disability Index (HAQ-DI) to assess the disease activity. Univariate and multivariate logistic regression analyses were performed to evaluate the risk factor for DWH.Results:The major characteristics of the patients in 277 procedures were mean age of 63.2 years old and mean disease duration of 18.2 years. Surgical site were hand and wrist (145 procedures), foot and ankle (76), hip and knee (31), elbow and shoulder (24), and spine (1). Seventy-four patients were treated with tocilizumab, 62 with etanercept, 55 with golimumab, 49 with abatacept, 16 with infliximab, 15 with adalimumab, and 6 with certolizumab. According to nutritional assessment in PNI and CONUT, 63% (n=175) and 47% (n=130) were normal nourished patients, respectively.In 277 procedures, DWH were identified in 24 patients (8.6%). The following variables were significant in the univariate analyses: disease duration (OR 1.053; 95% CI 1.010–1.099; p=0.016), foot and ankle surgery (OR 7.091; 95% CI 2.130–23.603; p=0.001), tocilizumab (OR 0.286; 95% CI 0.093–0.881; p=0.029) (Table 1). These variables were entered into a multivariate model, and it was revealed that pre-operative use of tocilizumab (OR 0.265; 95% CI 0.074–0.953; p=0.042) and procedures in the foot and ankle (OR 6.915; 95% CI 1.914–24.976; p=0.003) were associated with an increased risk of DWH (Table 1).Conclusion:As previous study on tocilizumab described, the current retrospective study suggested that pre-operative use of tocilizumab and procedures in the foot and ankle were risk factors for DWH. Pre-operative disease activity and nutritional status were not independent risk factors for an increase in the prevalence of DWH.References:[1] Momohara S, Hashimoto J, Tsuboi H et al. Analysis of perioperative clinical features and complications after orthopaedic surgery in rheumatoid arthritis patients treated with tocilizumab in a real-world setting: Results from the multicentre tocilizumab in perioperative period (TOPP) study. Modern rheumatology. 2013, 23: 440-9.Disclosure of Interests:Shunji Okita: None declared, Hajime Ishikawa: None declared, Asami Abe: None declared, Satoshi Ito Speakers bureau: Abbvie,Eisai, Akira Murasawa: None declared, Keiichiro Nishida Grant/research support from: K. Nishida has received scholarship donation from CHUGAI PHARMACEUTICAL Co., Eisai Co., Mitsubishi Tanabe Pharma and AbbVie GK., Speakers bureau: K. Nishida has received speaking fees from CHUGAI PHARMACEUTICAL Co., Eli Lilly, Janssen Pharmaceutical K.K., Eisai Co. and AYUMI Pharmaceutical Corporation., Toshifumi Ozaki: None declared

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Environmental risk factors and child nutritional status and survival in a context of climate variability and change

Applied Geography ◽

10.1016/j.apgeog.2014.08.007 ◽

2014 ◽

Vol 54 ◽

pp. 209-221 ◽

Cited By ~ 20

Author(s):

Kiersten Johnson ◽

Molly E. Brown

Keyword(s):

Risk Factors ◽

Nutritional Status ◽

Climate Variability ◽

Environmental Risk ◽

Environmental Risk Factors ◽

Climate Variability And Change ◽

Child Nutritional Status

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Prevalence and risk factors of hepatitis b infection in HIV infected children seen at national hospital Abuja

Nigerian Journal of Paediatrics ◽

10.4314/njp.v48i2.1 ◽

2021 ◽

Vol 48 (2) ◽

pp. 62-65

Author(s):

O.A. Adeoye ◽

O. Oniyangi ◽

I.A. Ojuawo

Keyword(s):

Risk Factors ◽

Hepatitis B ◽

Hepatitis B Surface Antigen ◽

Significant Risk ◽

Hepatitis B Vaccination ◽

Rapid Progression ◽

Hepatitis B Infection ◽

National Hospital ◽

Blood Samples ◽

Paediatric Hiv

Background: Human immunodeficiency virus infection remains a global pandemic. Co infection with hepatitis B virus leads to rapid progression to AIDS if not diagnosed and promptly treated or better still prevented. The study aims at determining the prevalence and risk factors of hepatitis B infection in HIV infected children being followed up at the Paediatric HIV clinic. Patients and methods: A cross-sectional study of 261 HIV infected children aged eight months to fourteen years to determine the prevalence of Hepatitis B infection and pattern of hepatitis B vaccination was carried out between July and October 2012 at the Paediatric HIV clinic of National Hospital Abuja. Ethical approval was obtained from Ethical Committee of the hospital. Vaccination and transfusion history were obtained from the parents and guardians of the subjects using a proforma after signed informed consent. Blood samples were collected for Hepatitis B surface antigen screening and Hepatitis B screening in those with HBsAg positive blood samples. Results: Only 3 (1.15%) of the 261 HIV infected children had Hepatitis B infection. All the children less than 5 years old in this cohort received hepatitis B vaccination and none of them had Hepatitis B infection. The HIV/HBV co infected children were older than ten years (p = 0.047) and history of blood transfusion (p = 0.003) was also significant. However, scarification (p = 0.996), local circumcision (p = 0.928); uvulectomy (p = 0.898) were not significant risk factors in this cohort. Conclusion: There is need to intensify routine hepatitis B vaccination and routine screening of blood before necessary transfusion. This would further lead to a low prevalence of Hepatitis B in HIV infected children and the general populace at large.

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A prospective cohort study of older colorectal cancer surgical patients: an association of post-operative clinical outcome with sarcopenia, frailty, and nutritional status [Protocol] (Preprint)

10.2196/preprints.16846 ◽

2019 ◽

Author(s):

Nia Humphry

Keyword(s):

Colorectal Cancer ◽

Risk Factors ◽

Nutritional Status ◽

Significant Proportion ◽

The Elderly ◽

Operative Risk ◽

Surgical Patients ◽

Clinical Frailty Scale ◽

Colorectal Cancer Surgery ◽

Colorectal Cancer Resection

UNSTRUCTURED Older patients account for a significant proportion of patients undergoing colorectal cancer surgery, and are vulnerable to a number of pre-operative risk factors that are not often present in younger patients. Three pre-operative risk factors more prevalent in the elderly are frailty, sarcopenia, and malnutrition. Whilst each of these has been studied in isolation, there is little information on the interplay between them in older surgical patients. One particular area of increasing interest is the use of urine metabolomics for objective evaluation of dietary profiles and malnutrition. Herein we describe the design, cohort, and standard operating procedures of a planned prospective study of older surgical patients undergoing colorectal cancer resection across multiple institutions in the United Kingdom. These procedures include serial frailty evaluations (Clinical Frailty Scale and Groningen Frailty Indicator), functional assessments (with hand grip strength and 4-metre walk test), muscle mass evaluations using computerized tomography morphometric analysis and evaluation of nutritional status using analysis of urinary dietary biomarkers. As these are all areas of common derangement in the elderly surgical population, prospectively studying them in concert will allow for analysis of their interplay as well as the development of predictive models for those at risk for commonly tracked surgical complications and outcomes.

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Prevalence and Determinants of Nutritional Status Among Women and Children in Pakistan

10.21203/rs.3.rs-646383/v1 ◽

2021 ◽

Author(s):

Hanumant Waghmare ◽

Shekhar Chauhan ◽

Santosh Kumar Sharma

Keyword(s):

Risk Factors ◽

Nutritional Status ◽

Rural Women ◽

Urban Women ◽

Wealth Quintile ◽

Educational Status ◽

Household Wealth ◽

Poor Nutritional Status ◽

Women And Children ◽

Status Of Women

Abstract Background: Nutrition has been a low-priority area in Pakistan, with low visibility from the political leadership. Despite various efforts, Pakistan has been reported to have one of the highest prevalence of child and women malnutrition compared to other developing counties. Therefore, this study intends to examine the prevalence and determinants of nutritional status of women and children in Pakistan.Methods: The present study uses the Demographic Health Survey (DHS) data from Pakistan 2012-13 (PDHS-3). The nutritional status of women was examined through Body-Mass Index (Underweight, normal, overweight, & obese), and that of children was examined through stunting (severe and moderate), wasting (severe, moderate, overweight), and underweight (severe, moderate, overweight). Descriptive statistics and bivariate analysis have been used along with multinomial logistic regression.Results: A higher proportion of children in rural areas were severely stunted (19.57% vs. 12.49%), severe wasted (2.36% vs. 2.23%), and severe underweight (9.37% vs. 6%) than their urban counterparts. A higher proportion of rural women (9.5% vs. 5.45%) were underweight than urban women, whereas a higher proportion of urban women were obese (24.32% vs. 19.01%) than rural women. The odds of severe stunting (OR= 0.24; C.I.=0.15-0.37), severe underweight (OR= 0.11; C.I.=0.05-0.22) were lower among children from the richest wealth quintile than their poorest counterparts. The Relative Risk Ratio (RRR) of being overweight (RRR= 3.7; C.I.=2.47-5.54) and Obese (RRR= 4.35; C.I.=2.67-7.07) than normal BMI were higher among women from richest wealth quintile than women belonged to poorest wealth quintile.Conclusion: This study has highlighted determinants associated with maternal and child nutritional status, whereby child’s nutritional status was measured by stunting, wasting, and underweight, and the mother’s nutritional status was measured by BMI. The main risk factors for child’s poor nutritional status include low household wealth, urban residence, and mother’s educational status. Similarly, the main risk factors for women’s poor nutritional status include increasing the women's age, educational status, rural residence, and household wealth. Emphasis should be placed on educating mothers as it would improve their nutritional status and improve their child’s nutritional status simultaneously.

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Dietary Practices and Nutritional Status of the Urban Vulnerable: A Cross Sectional Study on Waste Collectors of Dhaka City in Bangladesh

World Nutrition ◽

10.26596/wn.202011444-55 ◽

2020 ◽

Vol 11 (4) ◽

pp. 44-55

Author(s):

Asit Biswas ◽

M A Rifat ◽

Hazera Binte Sufian ◽

MD Khurshidul Zahid

Keyword(s):

Risk Factors ◽

Nutritional Status ◽

Multinomial Logistic Regression ◽

Cross Sectional Study ◽

Dietary Quality ◽

Dhaka City ◽

Dietary Practices ◽

Cross Sectional ◽

Multinomial Logistic Regression Analysis ◽

Main Meals

Purpose The socioeconomic conditions of urban waste collectors are vulnerable. However, their nutrition vulnerability remains undocumented. Here we focused on dietary practices and the nutritional status of waste collectors of Dhaka city in Bangladesh. Methods A cross-sectional design was employed that included 130 waste collectors from 15 different sites of Dhaka city. The 24-hours recall method, body mass index (BMI) and BMI for age Z-score were used to determine dietary practices and nutritional status respectively. Chi-square test, Fisher’s exact test, and multinomial logistic regression analysis were used to observe the associations and their risk factors. Results The majority (58.5%) of the waste collectors were normal by BMI whereas 36.2%, 4.5%, and 0.8% were underweight, overweight, and obese respectively. The prevalence of underweight was higher among males and respondents less than 18-years old (P<0.001). The dietary pattern of the respondents was poor. Meals were mainly rice and vegetable-based. Consumption of meats, eggs and fruits was low. Only 18.4% and 16.92% respondents were found to consume meat and eggs at least once a day, respectively. In addition, 78.5% consumed insufficient foods in their main meals, 9.2% had skipped meals and 13.1% consumed stale food and food waste regularly. Consumption of less than three main meals a day and food of poor dietary quality were risk factors of underweight. Conclusion Findings demonstrated that waste collectors in Dhaka city had poor nutritional status which was primarily associated with inadequate dietary intake. Increased quality and quantity of food in the diet, which could be achieved through appropriate health and nutritional support, are needed to overcome the situation.

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