scholarly journals ATXN2 and Its Neighbouring Gene SH2B3 Are Associated with Increased ALS Risk in the Turkish Population

PLoS ONE ◽  
2012 ◽  
Vol 7 (8) ◽  
pp. e42956 ◽  
Author(s):  
Suna Lahut ◽  
Özgür Ömür ◽  
Özgün Uyan ◽  
Zeynep Sena Ağım ◽  
Aslihan Özoğuz ◽  
...  
Keyword(s):  
Turkish Population ◽  
Neighbouring Gene

Türkiye'de iller arası göçlerin nodexl ile sosyal ağ analizi

2017 ◽  
Vol 4 (1) ◽  
pp. 82-109 ◽  
Author(s):  
Mustafa Yakar ◽  
Fatma Sert Eteman
Keyword(s):  
Network Structure ◽  
Population Data ◽  
Single Mode ◽  
Turkish Population ◽  
Place Of Birth ◽  
Place Of Residence ◽  
Migration Flow ◽  
Population Structures ◽  
The Republic ◽  
Provincial Scale

Türkiye'de 20.yy'ın ortasından itibaren başlayan iç göçler zamanla kurulan göçmen ağları ile süreklilik kazanmış ve ülke içinde nüfusun kır-kent dağılımını değiştirecek boyutlara erişmiştir. Araştırma, göçün doğum yeri verisinden hareketle ikamet edilen yerdeki nüfus miktarına göre alınan ve verilen göç akışının büyüklüğünü iller ölçeğinde yönlü ağlar kullanılarak analiz edilmesini amaçlamaktadır. Araştırmada, TÜİK tarafından yayınlanmış olan 2015 yılına ait, iller ölçeğinde doğum yerine göre ikamet yeri verisi kullanılmıştır. Göçün kaynak ve hedef sahaları arasındaki akışını incelemek için NodeXL ile oluşturulan tek modlu, yönlü ve ağırlıklandırılmış göç ağının istatistiksel olarak tam ağ yapısına sahip olduğu görülmüştür. Ağ grafiklerinden ve istatistiklerinden göç hareketinin doğudan batıya doğru gerçekleştiği ve İstanbul’ un ülkenin tamamına hâkim bir görünüme sahip olduğu anlaşılmaktadır. Türkiye nüfusunun cumhuriyet tarihi içinde geçirdiği iç göç süreçleriyle birlikte ülke içinde kurulmuş ve oldukça karmaşık bir görünüme sahip ağ yapısının olduğu ileri sürülebilir. Kurulan ağlar göçlerin devamını sağladığı gibi, göçün yöneldiği merkezlerde daha heterojen nüfus yapılarının ortaya çıkmasına yol açmıştır.ABSTRACT IN ENGLISHSocial Network Analysis of Migration Inter Provinces In Turkey with Nodexl The internal migrations which started in Turkey in the middle of the 20th century have gained permanency with the migration networks that were established at the time and reached dimensions which have the potential to change the rural-urban distribution of the population within the country.  The study aims to analyze the magnitude of the incoming and outgoing migration flow at the provincial scale based on the population data for place of birth according to place of residence by using directional networks. Place of residence according to place of birth at the provincial scale data for 2015 published by TÜİK was used in the study. A single mode, directional and weighted migration network created with NodeXL to examine the migration flows between the source and target has a statistically complete network structure. The network graphs and statistics show that the migrations have taken place from east to west and Istanbul has a view as dominant of the country. It can be argued that internal network structure of Turkish population has  a very complex view because of internal migration in the history of the republic. The established networks have enabled the continuation of migration and have manifested as the emergence of more heterogeneous population structures in centers where migration had been directed.

Investigation Between MTHFR A1298C polymorphism and Oral Squamous Cell Carcinoma Risk in Turkish Population

Experimed ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 44-52
Author(s):  
Ozlem Kucukhuseyin ◽  
◽  
Kivanc Bektas Kayhan ◽  
Meral Unur ◽  
Hulya Yilmaz Aydogan ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Turkish Population ◽  
Mthfr A1298c ◽  
A1298c Polymorphism ◽  
Carcinoma Risk

Association between Vaspin rs2236242 Gene Polymorphism and Psoriasis Vulgaris

2020 ◽  
pp. 1-6
Author(s):  
Nazli Dizen-Namdar ◽  
Raziye Akcilar ◽  
Zeynep Bayat
Keyword(s):  
Gene Polymorphism ◽  
Metabolic Disorders ◽  
Psoriasis Vulgaris ◽  
Turkish Population ◽  
Inflammatory Skin Disease ◽  
Control Groups ◽  
Diagnostic Biomarkers ◽  
Increased Risk ◽  
Visceral Adipose ◽  
And Control

<b><i>Background:</i></b> Psoriasis known as a chronic inflammatory skin disease is accompanied by metabolic disorders such as obesity, diabetes, and dyslipidemia. Vaspin (a serine protease inhibitor derived from visceral adipose tissue) is a newly identified adipokine and a link between inflammation and obesity has been reported. We aimed to determine whether vaspin gene polymorphism is associated with the development and/or clinical features of psoriasis vulgaris. <b><i>Methods:</i></b> Our study group consisted of 96 psoriasis vulgaris patients and 100 matched controls. Vaspin rs2236242 gene was genotyped using PCR. <b><i>Results:</i></b> The vaspin genotypes showed a meaningful difference between psoriasis and control groups (<i>p</i> = 0.02). The frequency of the vaspin rs2236242 TT genotype was lower in psoriasis patients than in control participants (<i>p</i> &#x3c; 0.05). The TA genotype was associated with a 2.38-fold increased risk of psoriasis compared to the TT genotype (<i>p</i> = 0.007, odds ratio: 2.38; 95% confidence interval: 1.25–4.55), but not the AA genotype. All subjects were the Turkish population, the study in other populations is needed and the sample size was small in number. <b><i>Conclusion:</i></b> Our study demonstrated that vaspin rs2236242 polymorphism is related to psoriasis in the Turkish population. Polymorphisms of the vaspin gene might serve as diagnostic biomarkers of psoriasis.

scholarly journals Ultrasonographic assessment of ossification of the distal radial epiphysis for estimating forensic age

2021 ◽  
Author(s):  
Oguzhan Ekizoglu ◽  
Ali Er ◽  
Asli Dilara Buyuktoka ◽  
Mustafa Bozdag ◽  
Gokce Karaman ◽  
...  
Keyword(s):  
Health Risk ◽  
Age Estimation ◽  
Turkish Population ◽  
Kappa Statistics ◽  
Left Wrist ◽  
Interobserver Error ◽  
Kappa Value ◽  
Critical Age ◽  
Age Limits ◽  
Ultrasonographic Assessment

AbstractSince forensic age estimation is not a valid medical indication, research on the use of nonionizing methods is increasing. Ultrasonography is a radiological approach that protects patients from radiation exposure and offers special convenience to them. In this study, ultrasonography was used for age estimation by investigating the degree of ossification of the distal radial epiphysis. Its applicability on the Turkish population was investigated. The left wrist of 688 (322 males, 366 females) patients between the ages of 9 and 25 years was prospectively evaluated by ultrasonography. The intra- and interobserver reliabilities in evaluating the distal radial epiphysis and Cohen’s kappa statistics show that the interobserver error was very low, and the kappa value was found to be 0.919. Stage 3 and 4 ossification of the distal radial epiphysis was first detected at age 14.3 and 15.3 years in males and 12.7 and 14.8 years in females, respectively. The data obtained may help determine legally critical age limits of 14 and 15. Although it does not seem useful for the age of 18, ultrasonography may be recommended in selected cases as a fast, inexpensive, frequently reproducible radiological method without concern about radiation and without a predictable health risk.

The Prevalence of Fabella in Turkish Population and the Association between the Presence of Fabella and Osteoarthritis

2021 ◽  
Author(s):  
Abdulkadir Sari ◽  
Yasar Mahsut Dincel ◽  
Mehmet Umit Cetin ◽  
Burak Gunaydin ◽  
Melih Guney
Keyword(s):  
Turkish Population

scholarly journals The Prevalence of Carotid Artery Calcification on the Panoramic Radiographs in Cappadocia Region Population

2007 ◽  
Vol 01 (03) ◽  
pp. 132-138 ◽  
Author(s):  
Yildiray Sisman ◽  
Elif Tarim Ertas ◽  
Cumali Gokce ◽  
Ahmed Menku ◽  
Mustafa Ulker ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Turkish Population ◽  
Smoking History ◽  
Panoramic Radiographs ◽  
Carotid Artery Calcification ◽  
Medical Evaluation ◽  
Life Saving ◽  
Males And Females ◽  
School Of Dentistry ◽  
And Gender

ABSTRACTObjectives: The aim of this study is to determine retrospectively the presence of carotid artery calcifications (CACs) detected on panoramic radiographs (PRs) in a group of Turkish population. Further, the relationships between CACs and gender, life style, and medical history were evaluated.Methods:During the years 2004 to 2006, a random sample of 1282 PRs was collected from patients older than 40 years who were being treated by the School of Dentistry, Erciyes University. Of these 1282 PRs, 750 PRs were included in this study. Medical data was collected from the archival records of the dental school.Results: About 38 (5.06%) CACs were found on the PRs of 12 (4.5%) males and 26 (5.4%) females. The CAC prevalence was not significantly different between the males and females (P=0.583). These calcifications were unilateral in 26 (68.4%) and bilateral in 12 (31.6%) subjects. Of those in the positive group, there were 12 subjects (31.58%) with hyperlipidemia, 12 subjects (31.58%) with hypertension, 7 subjects (18.4%) with diabetes mellitus, 6 subjects (15.8%) with cardiovascular disease, and 6 subjects (15.8%) with smoking history.Conclusions: This study has the highest CACs prevalence in comparison to the other studies. Therefore, dentists caring for subjects with dental problems should carefully evaluate their PRs for the evidence of CACs, and refer them for medical evaluation as indicated. So, incidental findings could provide life-saving information. (Eur J Dent 2007;1:132-138)

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