scholarly journals The Relationship between Bipolar Disorder and Cannabis Use in Daily Life: An Experience Sampling Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0118916 ◽  
Author(s):  
Elizabeth Tyler ◽  
Steven Jones ◽  
Nancy Black ◽  
Lesley-Anne Carter ◽  
Christine Barrowclough
2017 ◽  
Vol 41 (S1) ◽  
pp. S479-S479
Author(s):  
L. Montes Reula ◽  
A. Portilla Fernández ◽  
H. Saiz García

Cannabis is seen among general population as an “anti-depressive drug”. Many papers have been published in the field of investigation about the relationship between cannabis use and affective disorders. We pretend to find the aspect of the psychological consequences of cannabis use.MethodsUsing Pubmed and PsychInfo, we conducted a narrative review of the literature on cannabis and psychiatric comorbidity using the keywords cannabis, psychosis, mood, depression, mania, bipolar, and anxiety.ResultsThere is substantial evidence of an association between cannabis use and psychosis. A few reports suggest an association with bipolar disorder while the association with depression and anxiety disorders is mixed.ConclusionsThe present review confirms earlier findings of an association between cannabis use and a lower age at onset. Data shows that cannabis use, beginning in the adolescence and with a frequency higher than once a week, correlates with the development in adult age of affective symptoms and/or disorder, mainly in bipolar disorder, with a moderate relation with Depressive spectrum. Even more, some authors hypothesize that cannabis may play a role in the development of the disorder, that to say, affective disorder would not appear in the absence of cannabis use. The current findings suggest that recent cannabis use is associated with a more severe course of illness in the early phase of BD I.Recent cannabis use was also associated with more lifetime suicide attempts.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2020 ◽  
Author(s):  
Oskar Hougaard Jefsen ◽  
Maria Speed ◽  
Doug Speed ◽  
Søren Dinesen Østergaard

AbstractAimsCannabis use is associated with a number of psychiatric disorders, however the causal nature of these associations has been difficult to establish. Mendelian randomization (MR) offers a way to infer causality between exposures with known genetic predictors (genome-wide significant single nucleotide polymorphisms (SNPs)) and outcomes of interest. MR has previously been applied to investigate the relationship between lifetime cannabis use (having ever used cannabis) and schizophrenia, depression, and attention-deficit / hyperactivity disorder (ADHD), but not bipolar disorder, representing a gap in the literature.MethodsWe conducted a two-sample bidirectional MR study on the relationship between bipolar disorder and lifetime cannabis use. Genetic instruments (SNPs) were obtained from the summary statistics of recent large genome-wide association studies (GWAS). We conducted a two-sample bidirectional MR study on the relationship between bipolar disorder and lifetime cannabis use, using inverse-variance weighted regression, weighted median regression and Egger regression.ResultsGenetic liability to bipolar disorder was significantly associated with an increased risk of lifetime cannabis use: scaled log-odds ratio (standard deviation) = 0.0174 (0.039); P-value = 0.00001. Genetic liability to lifetime cannabis use showed no association with the risk of bipolar disorder: scaled log-odds ratio (standard deviation) = 0.168 (0.180); P-value = 0.351. The sensitivity analyses showed no evidence for pleiotropic effects.ConclusionsThe present study finds evidence for a causal effect of liability to bipolar disorder on the risk of using cannabis at least once. No evidence was found for a causal effect of liability to cannabis use on the risk of bipolar disorder. These findings add important new knowledge to the understanding of the complex relationship between cannabis use and psychiatric disorders.


2020 ◽  
pp. 113695
Author(s):  
T. Jordan Walter ◽  
Nina Pocuca ◽  
Jared W. Young ◽  
Mark A. Geyer ◽  
Arpi Minassian ◽  
...  

2020 ◽  
Author(s):  
T. Jordan Walter ◽  
Nina Pocuca ◽  
Jared W. Young ◽  
Mark A. Geyer ◽  
Arpi Minassian ◽  
...  

ABSTRACTBipolar disorder (BD) and cannabis use are highly comorbid and are each associated with cognitive impairment. It is therefore important to understand the relationship between cannabis use and cognition in people with BD, as cannabis use in BD may be associated with greater cognitive impairment. We performed a scoping review to determine how much and what is currently known in this field. We systematically searched PubMed, Embase, CINAHL, Web of Science, and PsycINFO for studies on the relationship between cannabis and cognition in people with BD or relevant animal models. Six observational human studies met inclusion criteria. Two studies found cannabis use in BD was associated with better performance in some cognitive domains, while three studies found no association. One study found cannabis use in BD was associated with worse overall cognition. Overall, most identified studies suggest cannabis use is not associated with significant cognitive impairment in BD; however, the scope of knowledge in this field is limited, and more systematic studies are clearly required. Future studies should focus on longitudinal and experimental trials, as well as well-controlled observational studies with rigorous quantification of the onset, frequency, quantity, duration, and type of cannabis use.


2020 ◽  
Author(s):  
Katherine N. Cotter ◽  
Paul Silvia

Mental control of musical imagery consists of two components: initiation—did you start it on purpose?—and management—did you alter, sustain, or end the experience after it began?. The present research examined these two components of mental control using both behavioral lab-based musical imagery tasks and self-reports of mental control in daily life using experience sampling methods. Both music students and members of the general university community participated. This project had four primary aims: (1) examining the relationship between initiation and management of musical imagery; (2) assessing how mental control abilities differ as a function of stimulus type; (3) describing perceptions of initiation and management in daily life; and (4) evaluating how well performance on lab-based behavioral tasks aligns with self-reported mental control in daily life. The findings suggest that initiation and management abilities are closely related, people perform equivalently when asked to control tonal stimuli and song stimuli, people generally report the ability to control musical imagery in daily life, and self-report and behavioral assessments of mental control of musical imagery show a modest association. These findings have implications for current understandings of control of musical imagery and identify several avenues for future research.


2003 ◽  
Vol 33 (1) ◽  
pp. 23-32 ◽  
Author(s):  
H. VERDOUX ◽  
C. GINDRE ◽  
F. SORBARA ◽  
M. TOURNIER ◽  
J. D. SWENDSEN

Background. Epidemiological findings suggest that cannabis use is a risk factor for the emergence of psychosis, and that the induction of psychotic symptoms in the context of cannabis use may be associated with a pre-existing vulnerability for psychosis. This study investigated in a non-clinical population the interaction between cannabis use and psychosis vulnerability in their effects on psychotic experiences in daily life.Method. Subjects (N = 79) with high or low levels of cannabis use were selected among a sample of 685 undergraduate university students. Experience sampling method (ESM) was used to collect information on substance use and psychotic experiences in daily life. Vulnerability to develop psychosis was measured using a clinical interview assessing the level of psychotic symptoms. Statistical analyses were performed using multilevel linear random regression models.Results. The acute effects of cannabis are modified by the subject's level of vulnerability for psychosis. Subjects with high vulnerability for psychosis are more likely to report unusual perceptions as well as feelings of thought influence than subjects with low vulnerability for psychosis, and they are less likely to experience enhanced feelings of pleasure associated with cannabis. There is no evidence that use of cannabis is increased following occurrence of psychotic experiences as would be expected by the self-medication model.Conclusion. Cannabis use interacts with psychosis vulnerability in their effects on experience of psychosis in daily life. The public health impact of the widespread use of cannabis may be considerable.


2016 ◽  
Vol 37 (3) ◽  
pp. 181-193 ◽  
Author(s):  
Aire Mill ◽  
Anu Realo ◽  
Jüri Allik

Abstract. Intraindividual variability, along with the more frequently studied between-person variability, has been argued to be one of the basic building blocks of emotional experience. The aim of the current study is to examine whether intraindividual variability in affect predicts tiredness in daily life. Intraindividual variability in affect was studied with the experience sampling method in a group of 110 participants (aged between 19 and 84 years) during 14 consecutive days on seven randomly determined occasions per day. The results suggest that affect variability is a stable construct over time and situations. Our findings also demonstrate that intraindividual variability in affect has a unique role in predicting increased levels of tiredness at the momentary level as well at the level of individuals.


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