scholarly journals The Relationship between Cannabis Use and Cognition in People with Bipolar Disorder: A Systematic Scoping Review

2020 ◽  
pp. 113695
Author(s):  
T. Jordan Walter ◽  
Nina Pocuca ◽  
Jared W. Young ◽  
Mark A. Geyer ◽  
Arpi Minassian ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Scoping Review ◽  
Cannabis Use ◽  
The Relationship

scholarly journals The Relationship between Cannabis Use and Cognition in People with Bipolar Disorder: A Systematic Scoping Review

2020 ◽  
Author(s):  
T. Jordan Walter ◽  
Nina Pocuca ◽  
Jared W. Young ◽  
Mark A. Geyer ◽  
Arpi Minassian ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Cognitive Impairment ◽  
Scoping Review ◽  
Web Of Science ◽  
Cannabis Use ◽  
Inclusion Criteria ◽  
Cognitive Domains ◽  
Future Studies ◽  
Experimental Trials ◽  
The Relationship

ABSTRACTBipolar disorder (BD) and cannabis use are highly comorbid and are each associated with cognitive impairment. It is therefore important to understand the relationship between cannabis use and cognition in people with BD, as cannabis use in BD may be associated with greater cognitive impairment. We performed a scoping review to determine how much and what is currently known in this field. We systematically searched PubMed, Embase, CINAHL, Web of Science, and PsycINFO for studies on the relationship between cannabis and cognition in people with BD or relevant animal models. Six observational human studies met inclusion criteria. Two studies found cannabis use in BD was associated with better performance in some cognitive domains, while three studies found no association. One study found cannabis use in BD was associated with worse overall cognition. Overall, most identified studies suggest cannabis use is not associated with significant cognitive impairment in BD; however, the scope of knowledge in this field is limited, and more systematic studies are clearly required. Future studies should focus on longitudinal and experimental trials, as well as well-controlled observational studies with rigorous quantification of the onset, frequency, quantity, duration, and type of cannabis use.

scholarly journals The Effects of Cannabis Use on Cognitive Function in Healthy Aging: A Systematic Scoping Review

2020 ◽  
Author(s):  
Nina Pocuca ◽  
T Jordan Walter ◽  
Arpi Minassian ◽  
Jared W Young ◽  
Mark A Geyer ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Scoping Review ◽  
Healthy Aging ◽  
Web Of Science ◽  
Cannabis Use ◽  
Future Research ◽  
Meta Analyses ◽  
Older Populations ◽  
The Relationship ◽  
Chronic Doses

Abstract Background Older adults (≥50 years) represent the fastest-growing population of people who use cannabis, potentially due to the increasing promotion of cannabis as medicine by dispensaries and cannabis websites. Given healthy aging and cannabis use are both associated with cognitive decline, it is important to establish the effects of cannabis on cognition in healthy aging. Objective This systematic scoping review used preferred reporting items for systematic reviews and meta-analyses guidelines to critically examine the extent of literature on this topic and highlight areas for future research. Method A search of six databases (PubMed, EMBASE, PsycINFO, Web of Science, Family and Society Studies Worldwide, and CINAHL) for articles published by September 2019, yielded 1,014 unique results. Results Six articles reported findings for older populations (three human and three rodent studies), highlighting the paucity of research in this area. Human studies revealed largely null results, likely due to several methodological limitations. Better-controlled rodent studies indicate that the relationship between ∆9-tetrahydrocannabinol (THC) and cognitive function in healthy aging depends on age and level of THC exposure. Extremely low doses of THC improved cognition in very old rodents. Somewhat higher chronic doses improved cognition in moderately aged rodents. No studies examined the effects of cannabidiol (CBD) or high-CBD cannabis on cognition. Conclusions This systematic scoping review provides crucial, timely direction for future research on this emerging issue. Future research that combines neuroimaging and cognitive assessment would serve to advance understanding of the effects of age and quantity of THC and CBD on cognition in healthy aging.

scholarly journals The Relationship between Bipolar Disorder and Cannabis Use in Daily Life: An Experience Sampling Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0118916 ◽  
Author(s):  
Elizabeth Tyler ◽  
Steven Jones ◽  
Nancy Black ◽  
Lesley-Anne Carter ◽  
Christine Barrowclough
Keyword(s):  
Bipolar Disorder ◽  
Daily Life ◽  
Experience Sampling ◽  
Cannabis Use ◽  
The Relationship

Aspects of the psychological consequences of cannabis use

2017 ◽  
Vol 41 (S1) ◽  
pp. S479-S479
Author(s):  
L. Montes Reula ◽  
A. Portilla Fernández ◽  
H. Saiz García
Keyword(s):  
Bipolar Disorder ◽  
Suicide Attempts ◽  
Age At Onset ◽  
Cannabis Use ◽  
Psychological Consequences ◽  
Course Of Illness ◽  
Adult Age ◽  
Affective Symptoms ◽  
Competing Interest ◽  
The Relationship

Cannabis is seen among general population as an “anti-depressive drug”. Many papers have been published in the field of investigation about the relationship between cannabis use and affective disorders. We pretend to find the aspect of the psychological consequences of cannabis use.MethodsUsing Pubmed and PsychInfo, we conducted a narrative review of the literature on cannabis and psychiatric comorbidity using the keywords cannabis, psychosis, mood, depression, mania, bipolar, and anxiety.ResultsThere is substantial evidence of an association between cannabis use and psychosis. A few reports suggest an association with bipolar disorder while the association with depression and anxiety disorders is mixed.ConclusionsThe present review confirms earlier findings of an association between cannabis use and a lower age at onset. Data shows that cannabis use, beginning in the adolescence and with a frequency higher than once a week, correlates with the development in adult age of affective symptoms and/or disorder, mainly in bipolar disorder, with a moderate relation with Depressive spectrum. Even more, some authors hypothesize that cannabis may play a role in the development of the disorder, that to say, affective disorder would not appear in the absence of cannabis use. The current findings suggest that recent cannabis use is associated with a more severe course of illness in the early phase of BD I.Recent cannabis use was also associated with more lifetime suicide attempts.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Bipolar disorder and cannabis use: a bidirectional two-sample Mendelian randomization study

2020 ◽  
Author(s):  
Oskar Hougaard Jefsen ◽  
Maria Speed ◽  
Doug Speed ◽  
Søren Dinesen Østergaard
Keyword(s):  
Bipolar Disorder ◽  
Standard Deviation ◽  
Odds Ratio ◽  
Mendelian Randomization ◽  
Causal Effect ◽  
Cannabis Use ◽  
Genome Wide ◽  
Log Odds ◽  
The Relationship ◽  
Mr Study

AbstractAimsCannabis use is associated with a number of psychiatric disorders, however the causal nature of these associations has been difficult to establish. Mendelian randomization (MR) offers a way to infer causality between exposures with known genetic predictors (genome-wide significant single nucleotide polymorphisms (SNPs)) and outcomes of interest. MR has previously been applied to investigate the relationship between lifetime cannabis use (having ever used cannabis) and schizophrenia, depression, and attention-deficit / hyperactivity disorder (ADHD), but not bipolar disorder, representing a gap in the literature.MethodsWe conducted a two-sample bidirectional MR study on the relationship between bipolar disorder and lifetime cannabis use. Genetic instruments (SNPs) were obtained from the summary statistics of recent large genome-wide association studies (GWAS). We conducted a two-sample bidirectional MR study on the relationship between bipolar disorder and lifetime cannabis use, using inverse-variance weighted regression, weighted median regression and Egger regression.ResultsGenetic liability to bipolar disorder was significantly associated with an increased risk of lifetime cannabis use: scaled log-odds ratio (standard deviation) = 0.0174 (0.039); P-value = 0.00001. Genetic liability to lifetime cannabis use showed no association with the risk of bipolar disorder: scaled log-odds ratio (standard deviation) = 0.168 (0.180); P-value = 0.351. The sensitivity analyses showed no evidence for pleiotropic effects.ConclusionsThe present study finds evidence for a causal effect of liability to bipolar disorder on the risk of using cannabis at least once. No evidence was found for a causal effect of liability to cannabis use on the risk of bipolar disorder. These findings add important new knowledge to the understanding of the complex relationship between cannabis use and psychiatric disorders.

scholarly journals A Scoping Review of Associations Between Cannabis Use and Anxiety in Adolescents and Young Adults

2021 ◽  
Author(s):  
Colleen Stiles-Shields ◽  
Joseph Archer ◽  
Jim Zhang ◽  
Amanda Burnside ◽  
Janel Draxler ◽  
...  
Keyword(s):  
Young Adults ◽  
Young People ◽  
Scoping Review ◽  
Positive Association ◽  
Database Search ◽  
Negative Association ◽  
Cannabis Use ◽  
Adolescents And Young Adults ◽  
Clear Association ◽  
The Relationship

AbstractCannabis and anxiety are both rising issues that impact young people. This review seeks to explore the association between anxiety and cannabis in adolescents and young adults (AYA). A database search was run retrospectively from July 2020 through calendar year 2013. Articles had to present outcomes examining cannabis use and symptoms of anxiety, be written in English, contain samples with ≥ 50% who are age 25 or younger, and be published in a peer-reviewed journal. Forty-seven studies were identified that examined the relationship between anxiety and cannabis use. Twenty-three studies found a positive association that greater anxiety among AYA was associated with greater cannabis use. In contrast, seven studies found a negative association that greater anxiety was related to less cannabis use. And finally, 17 studies found no clear association between anxiety and cannabis use. Further research is needed to better understand the relationship between anxiety and cannabis use.

scholarly journals How hospitalized patients evaluate and report their pain together with nurses: A scoping review

2021 ◽  
pp. 205715852110134
Author(s):  
Bente Dale Malones ◽  
Sindre Sylte Kallmyr ◽  
Vera Hage ◽  
Trude Fløystad Eines
Keyword(s):  
Scoping Review ◽  
Pain Assessment ◽  
Health Professionals ◽  
Clinical Care ◽  
Hospitalized Patients ◽  
Assessment Tools ◽  
Post Surgery ◽  
Reliable Assessment ◽  
Scoping Reviews ◽  
The Relationship

Pain assessment tools are often used by patients to report their pain and by health professionals to assess patients’ reported pain. Although valid and reliable assessment of pain is essential for high-quality clinical care, there are still many patients who experience inappropriate pain management. The aim of this scoping review is to examine an overview of how hospitalized patients evaluate and report their pain in collaboration with nurses. Systematic searches were conducted, and ten research articles were included using the PRISMA guidelines for scoping reviews. Content analysis revealed four main themes: 1) the relationship between the patient and nurse is an important factor of how hospitalized patients evaluate and report their post-surgery pain, 2) the patient’s feelings of inconsistency in how pain assessments are administered by nurses, 3) the challenge of hospitalized patients reporting post-surgery pain numerically, and 4) previous experiences and attitudes affect how hospitalized patients report their pain. Pain assessment tools are suitable for nurses to observe and assess pain in patients. Nevertheless, just using pain assessment tools is not sufficient for nurses to obtain a comprehensive clinical picture of each individual patient with pain.

scholarly journals Cannabis use, sedentary behavior, and physical activity in a nationally representative sample of US adults

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Lydia Q. Ong ◽  
John Bellettiere ◽  
Citlali Alvarado ◽  
Paul Chavez ◽  
Vincent Berardi
Keyword(s):  
Physical Activity ◽  
Sedentary Behavior ◽  
Vigorous Physical Activity ◽  
Health Impact ◽  
Cannabis Use ◽  
Objective Measures ◽  
Health And Nutrition ◽  
Nationally Representative ◽  
The Relationship ◽  
Potential Public Health

Abstract Background Prior research examining the relationship between cannabis use, sedentary behavior, and physical activity has generated conflicting findings, potentially due to biases in the self-reported measures used to assess physical activity. This study aimed to more precisely explore the relationship between cannabis use and sedentary behavior/physical activity using objective measures. Methods Data were obtained from the 2005–2006 National Health and Nutrition Examination Survey. A total of 2,092 participants (ages 20–59; 48.8% female) had accelerometer-measured sedentary behavior, light physical activity, and moderate-to-vigorous physical activity. Participants were classified as light, moderate, frequent, or non-current cannabis users depending on how often they used cannabis in the previous 30 days. Multivariable linear regression estimated minutes in sedentary behavior/physical activity by cannabis use status. Logistic regression modeled self-reported moderate-to-vigorous physical activity in relation to current cannabis use. Results Fully adjusted regression models indicated that current cannabis users’ accelerometer-measured sedentary behavior did not significantly differ from non-current users. Frequent cannabis users engaged in more physical activity than non-current users. Light cannabis users had greater odds of self-reporting physical activity compared to non-current users. Conclusions This study is the first to evaluate the relationship between cannabis use and accelerometer-measured sedentary behavior and physical activity. Such objective measures should be used in other cohorts to replicate our findings that cannabis use is associated with greater physical activity and not associated with sedentary behavior in order to fully assess the potential public health impact of increases in cannabis use.

Sign in / Sign up

Export Citation Format

Share Document