scholarly journals Adverse events following the first dose of Covishield (ChAdOx1 nCoV-19) vaccination among health workers in selected districts of central and western Nepal: A cross-sectional study

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0260638
Author(s):  
Prativa Subedi ◽  
Gopal Kumar Yadav ◽  
Binod Paudel ◽  
Anu Regmi ◽  
Prajjwal Pyakurel

Introduction The study aimed at exploring the adverse events following immunization (AEFI) and their incidences among health workers in three different districts of central and western Nepal following the first dose of Covishield vaccine,. It also aimed at studying the association of AEFI with demographic and clinical characteristics of vaccinees, pre-vaccination anxiety level and prior history of COVID-19 infection (RT- PCR confirmed) status. Materials and methods This was a cross-sectional study carried out via face-to-face or telephonic interview among 1006 health workers one week after receiving their first dose of the Covishield vaccine. Incidence of adverse events was calculated in percentage while Chi-square Test was used to check the association of AEFI with independent variables. Logistic regression was used to find out the adjusted odd’s ratio at 95% CI. Results Incidence of AEFI was 79.8% with local and systemic AEFI being 68.0% and 59.7% respectively. Injection site tenderness was the commonest manifestation. Local and systemic symptoms resolved in less than one week among 96.8% and 98.7% vaccinees respectively. Females were more likely to develop AEFI than males (AOR = 1.7, 95% CI = 1.2–2.4). Vaccinees aged 45–59 years were 50% less likely to develop AEFI as compared to those aged less than 30 years (AOR 0.5, 95% CI = 0.3–0.8). Most of the vaccinees had not undergone RT-PCR testing for COVID-19 (59.8%). Those who were not tested for COVID-19 prior were 1.5 odds more likely to develop AEFI compared to those who were negative (AOR = 1.5, 95% CI = 1.1–2.1). Conclusion More than two-third of the vaccinees developed one or more forms of adverse events, but most events were self-limiting. Females and young adults were more prone to develop AEFI.

Cephalalgia ◽  
2020 ◽  
Vol 40 (13) ◽  
pp. 1443-1451 ◽  
Author(s):  
Pedro Augusto Sampaio Rocha-Filho ◽  
João Eudes Magalhães

Objectives To assess the frequency and characteristics of headache in patients with COVID-19 and whether there is an association between headache and anosmia and ageusia. Methods This was a cross-sectional study. Consecutive patients admitted to hospital with COVID-19, confirmed by reverse transcription polymerase chain reaction (RT-PCR) technique, were assessed by neurologists. Results Seventy-three patients were included in the study, 63% were male; the median age was 58 years (IQR: 47–66). Forty-seven patients (64.4%) reported headaches, which had most frequently begun on the first day of symptoms, were bilateral (94%), presenting severe intensity (53%) and a migraine phenotype (51%). Twelve patients (16.4%) presented with headache triggered by coughing. Eleven (15%) patients reported a continuous headache. Twenty-eight patients (38.4%) presented with anosmia and 29 (39.7%) with ageusia. Patients who reported hyposmia/anosmia and/or hypogeusia/ageusia experienced headache more frequently than those without these symptoms (OR: 5.39; 95% CI:1.66–17.45; logistic regression). Patients with anosmia and ageusia presented headache associated with phonophobia more often compared to those with headache without these complaints (Chi-square test; p < 0.05). Headache associated with COVID-19 presented a migraine phenotype more frequently in those experiencing previous migraine ( p < 0.05). Conclusion Headaches associated with COVID-19 are frequent, are generally severe, diffuse, present a migraine phenotype and are associated with anosmia and ageusia.


2020 ◽  
Vol 5 (2) ◽  
pp. 104-116
Author(s):  
Eva Nurhidayati ◽  
Emdat Suprayitno

Background: K4 is the fourth prenatal check-up visit for health workers to obtain antenatal care according to standards and to detect complications as early as possible during pregnancy. The K4 coverage in Batang-Batang Daya village, the working area of ​​the Batang-Batang Puskesmas is still below the target in 2018. The purpose of this study was to determine the relationship between husband's support and the decision of pregnant women in carrying out K4 examinations. Methods: The design of this study is analytic correlational with a cross-sectional study approach, the population of pregnant women in the third trimester of pregnancy in Batang-Batang Daya Village in 2019 was 27 respondents, using total sampling techniques, husband's support data was collected using a valid and reliable questionnaire. K4 examination data used a checklist in the KIA book, and the statistical test used was Chi-Square with an expected value of less than 5. Result: The results showed that most of the pregnant women received support from their husbands as many as 20 people (74.1). Most of the pregnant women underwent a K4 examination (4th pregnancy visit), as many as 20 people (74.1%). The analysis result from the Chi-Square test shows the value (ρ) = 0.000. Conclusion: It can be concluded that the husband's support is related to the decision by pregnant women to carry out K4 examinations. Husbands should always provide support to their wives to carry out routine checks so that pregnant women are motivated to carry out K4 examinations, and are more confident about carrying out their pregnancy.


2018 ◽  
Vol 5 (1) ◽  
pp. 16-21
Author(s):  
Poonam Shrestha ◽  
Sanjay Kumar Singh ◽  
Diwa Hamal ◽  
Afaque Anwar

Introductions: To assess the level of awareness and willingness of eye donation among eye health workers and compare it among the two institutes, one with cornea transplant services and other without cornea transplant services. Methods: This was comparative, questionnaire based, cross- sectional study under taken among eye health workers in two institutes. The questionnaire contained questions on demographic details, their awareness on eye donation, reasons for donating and not donating eyes by people as perceived by them, their intention to donate eyes and source of information. The responses were compared and statistically analyzed using chi-square test. Results: Of the 178 participants 132 participants were aware that eye donation was donation of eye after death. The most common source of information about eye donation was from eye professional. It was observed that 107 participants knew that eyes can be donated after death ideally within 6-8 hours of death. 139 respondents believed donated eye gives good sight to blind. Lack of awareness was cited as an important reason for people not donating eyes. Conclusions: Eye health workers are well aware about eye donation they can be actively involved in eye donation campaigns in community level and can act as counselors for eye donors.


Author(s):  
Harpreet Singh ◽  
Kanwaljit Kaur ◽  
S. K. Ghai ◽  
Pranaya Gurmeet ◽  
Raju Agarwal ◽  
...  

Background: COVID-19 pandemic is one of the greatest challenges faced worldwide and has not only posed health crisis but also had social, economic and political devastating effects. The speedy transmission risk enforced bygone practices of quarantine of healthy persons and isolation of all positive patients. The basis of all key policy making is the understanding of virus clearance from the body so that transmission can be ceased. The aim of the study was to understand the viral clearance and its’ co-relates for guiding infection control and transmission practices in COVID-19.Methods: Cross sectional study in a tertiary care hospital. A cross-sectional study of total 398 patients admitted for COVID-19 between June 2020 and November 2020 at a tertiary care centre. Statistical analysis used: frequency, percentage, and chi square test Chi square test for linear trend and was used to find association.Results: 88.19% were males and 11.81% were female patients, mean age of study participants was 34.84 years. 61.56% were symptomatic and among them 1.64% presented with severe symptoms. Mean duration to turn RT-PCR negative was 11.83 days. No significant difference in time taken to turn RT-PCR negative among asymptomatic and symptomatic cases is suggestive of no difference in viral load and its clearance in symptomatic vs asymptomatic cases.Conclusions: The disease profile of COVID-19 in our setup was alike the national disease profile and the recovery rate being 98.76%. Presence of co-morbidities affects viral clearance in COVID-19.


2018 ◽  
Vol 3 (3) ◽  
pp. 440
Author(s):  
Sri Handayani ◽  
Puteri Fannya ◽  
Putri Nazofah

<p><em>Based on data from the Indonesia Ministry of Health in 2015, In Indonesia, new professional nurses were just 2% of the total nurses. This figure was much lower than the Philippines which has reached 40% with bachelor and master level as their education. The purpose of this study was to determine the relationship between age, and leadership with the performance of health personnel</em><em>. </em><em>The design of this research was analytical research with Cross Sectional Study. The population in this study was all nurses and doctors who served in the internal room, children, surgery and midwifery</em><em>. </em><em>Sampling using total sampling</em><em> </em><em>by questionnaires. The data was processed by univariate and bivariate analysis using Chi-square test</em><em>. </em><em>The result showed that 57,8% nurses had poor performance, 56,3% doctors had poor performance, 64,4% nurses had average age 26-35 years, 56,2% doctors had average age  36-45 years, 64.4% nurses have poor leadership, </em><em>and </em><em>50.0% of doctors have less good leadership</em><em>.</em><em> There is a relationship between age</em><em> and </em><em>leadership with the performance of health personnel.</em><em></em></p><p><strong><em> </em></strong></p><p>Berdasarkan data kemenkes RI tahun 2015 jumlah tenaga kesehatan terbanyak yaitu perawat sebanyak 147.264 orang (45,65%). Di Indonesia, perawat profesional baru mencapai 2% dari total perawat yang ada. Angka ini jauh lebih rendah dibandingkan dengan Filipina yang sudah mencapai 40% dengan pendidikan strata satu dan dua. Tujuan penelitian ini untuk mengetahui hubungan antara umur, kepemimpinan dengan kinerja tenaga kesehatan. Jenis penelitian yang digunakan adalah desain penelitian analitik dengan Cross Sectional Study. Populasi pada penelitian ini adalah semua perawat dan dokter. Pengambilan sampel dengan menggunakan Total Sampling. Pengambilan data menggunakan kuesioner. Data diolah dengan analisis univariat menggunakan statistik deskriptif dan analisis bivariat menggunakan uji Chi-square. Hasil penelitian didapatkan 57,8% perawat memiliki kinerja kurang baik, 56,3% dokter memiliki kinerja kurang baik, 64,4% perawat memiliki umur rata-rata 26-35 tahun 64,4%, 56,2% dokter memiliki umur rata-rata 36-45 tahun, 64,4% perawat memiliki kepemimpinan kurang baik, 50,0% dokter memiliki kepemimpinan kurang baik. Terdapat hubungan antara umur dan kepemimpinan dengan kinerja tenaga kesehatan.</p>


2020 ◽  
Vol 54 (4) ◽  
pp. 225-230
Author(s):  
Marc Tshilanda ◽  
Ulrick S. Kanmounye ◽  
Remy Kapongo ◽  
Michel Tshiasuma

Objectives: Stroke is one of the leading causes of death, disability, and dementia in developing countries. Our study aimed to evaluate the systemic disorders associated with mortality in patients admitted within 72 hours of the initial stroke event. Setting: The study took place at a tertiary hospital in Kinshasa. Participants: Patients admitted within 72 hours of the initial stroke event. Interventions: This cross-sectional study consisted of a retrospective review of stroke patient records from January 2016 to December 2018. The Pearson-Chi square test and odds ratios were calculated with a threshold of significance of 0.05. Main outcome measures: Mortality Results: We recruited 114 cases. The mean age was 61.8 ± 2.4 years, and the sex ratio was 1.78 in favor of men. Hypertension (76.3%), dyslipidemia (71.1%), and diabetes mellitus (58.8%) were the most frequent comorbidities. Most patients had hypoxia (85.9%), hypertension (82.4%), hyperglycemia (57.8%), and fever (28.1%). We registered thirty-two deaths (28.1%): 20 (62.5%) from the ischemic strokes, and 12 (37.5%) from hemorrhagic strokes. Systemic disorders with the worst prognosis during were arterial hypotension (OR=3.87, p >0.001), and fever (OR = 1.56, p = 0.047). Conclusion: Arterial hypotension and fever adversely affect stroke patient outcomes, and strokes are responsible for high mortality in Congo


2020 ◽  
Vol 15 (1) ◽  
pp. 6-9
Author(s):  
Irmayani

Diare adalah pengeluaran kotoran (tinja) dengan frekuensi yang meningkat (tiga kali dalam 24 jam) disertai dengan perubahan konsistensi tinja menjadi lembek atau cair, dengan atau tanpa darah/lendir dalam tinja.(Wijoyo, yosef 2013). Penelitian ini bertujuan untuk mengetahui hubungan kebiasaan jajan dengan terjadinya penyakit diare pada anak di SD Inpres Amaro Kabupaten barru. Penelitian ini dilakukan dengan menggunakan jenis penelitian Analitik Correlative dengan desain Cross Sectional Study, populasi dalam penelitian ini adalah siswa yang ada di SD Inpres Amaro Kabupaten Barru sebanyak 109 orang. Pengambilan sampel menggunakan teknik purposive sampling, didapatkan 51 responden sesuai dengan kriteria inklusi. Pengumpulan data dilakukan dengan menggunakan kuesioner. analisa data mencakup analisis univariat dengan mencari distribusi frekuensi, analisis bivariat menggunakan uji Chi- Square Test dengan interval kemaknaan α 0,05. Dari hasil analisis bivariat pada kebiasaan jajan didapat nilai ρ = 0,004 dan personal hygiene didapat nilai ρ = 0,008. Kesimpulan dalam penelitian ini adalah terdapat hubungan antara kebiasaan jajan dengan terjadinya penyakit diare pada anak di SD Inpres Amaro Kabupaten Barru


2020 ◽  
Author(s):  
Milad Al-kalisi ◽  
Manal Al-Hajri ◽  
Sarah Al-Rai

Abstract Background: Undernutrition is an inadequate supply of energy and nutrients. Periodontal diseases (PDs) defined as a broad form of chronic inflammatory diseases of the gingiva, bone and ligaments supporting the teeth. This study aimed to reveal the effect of undernutrition, using body mass index (BMI) and serum albumin level (Alb) on PDs and other risk factors as age, smoking and khat chewing. Methods: This was a cross-sectional study conducted at the faculty of dentistry, Sana’a University. Of 1920 patients attended to clinics, only 229 matched the study criteria. Oral examination was performed to assess the periodontal clinical parameters measurements. BMI and Alb was measured. Statistical analysis was used to present the association between categorical variables was assessed using Chi square test and Fisher-Exact test. ANOVA was used to assess the differences in the mean values of the quantitative outcomes. Chi square test was used to evaluate the association between BMI and age, gender, occupation, education level, smoking, khat chewing as well as BMI with PDs. Results: Most of participants (58.5%) were males and most of the study sample (91.3%) was at the age group of (18-35). Among all subjects, (81.2%) of cases were diagnosed with gingivitis. (60.7%) of study participants were mildly undernourished according to BMI. (93%) of participants showed normal Alb level. Regarding to habits, only (18.2%) of patients were smokers and more than half of participants (59.4%) were khat chewers. Conclusion: There was a relationship between PDs and undernutrition which was obviously seen between gingivitis and mild undernutrition.


CoDAS ◽  
2021 ◽  
Vol 33 (6) ◽  
Author(s):  
Silvia Márcia Andrade Campanha ◽  
Roberta Lopes de Castro Martinelli ◽  
Durval Batista Palhares

ABSTRACT Purpose Verify the position of lips and tongue at rest in newborns with and without ankyloglossia. Methods Cross-sectional study, carried out with 130 newborns in University Hospital. Data collection was performed by the researcher and speech-language pathologists from the Hospital. Information on gestational age, sex, weight, height and days of life was collected. The position of the lips and tongue at rest was evaluated through visual inspection with the newborns asleep. After the newborns were awakened, Neonatal Screening of the validated Protocol for the evaluation of the lingual frenulum for infants was performed to detect the alteration of the lingual frenulum. The data obtained were described and submitted to statistical analysis using the Chi-Square test to verify the association between the position of the lips with the tongue and to compare the position of the lips and tongue with and without ankyloglossia. The Mann-Whitney test was used to verify the behavior of the variables the differed between newborns with and without ankyloglossia. The significance level of 5% was adopted. Results When comparing the data, a significant difference was found between: weight and height with and without ankyloglossia; position of lips and tongue. An association between the position of the tongue and lips with and without ankyloglossia was also found. Conclusion Newborns without alteration of the lingual frenulum have a tendency to remain with their lips closed and their tongue elevated during rest and newborns with ankyloglossia have a tendency to keep their lips parted and their tongue low during rest.


2020 ◽  
Vol 4 (1-3) ◽  
pp. 38
Author(s):  
Marie Christabelle ◽  
Bernie Endyarni Medise

Objective: In different parts of the world, Indonesia included, overweight and obese people are seen to have worse performance compared to their healthy counterparts. Although there were research that had been done to observe the relationship between overweight, obesity, and academic performance, the results obtained were still divided into significantly and non-significantly related.Methods: A cross-sectional study was done to 373 students from two different schools in South Jakarta on December 2017–January 2018. Data was obtained by measuring height and weight of the participant to get his/her nutritional status and the average of participant’s odd semester Continual Assessment and Semestral Assessment of Academic Year 2017/2018 to see if the result was higher or equal to the passing grade.Results: Data analysis with chi square test shows that there was no significant relationship between overweight, obesity, and academic performance (p = 0.452 for Indonesian Language and p = 0.476 for Mathematics) although overweight and obese students tend to have better performance in some exam.Conclusion: The events that lead to overweight, obesity, and one’s academic performance are all multifactorial that the relationship between the two is difficult to be determined.


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