scholarly journals Prevalence and risk factors of retinopathy of prematurity

2012 ◽  
Vol 52 (3) ◽  
pp. 138 ◽  
Author(s):  
Cut Badriah ◽  
Idham Amir ◽  
Elvioza Elvioza ◽  
Evita Ifran
Keyword(s):  
Risk Factors ◽  
Retinopathy Of Prematurity ◽  
Significant Risk ◽  
Extremely Low Birth Weight ◽  
Chi Square ◽  
Discriminative Ability ◽  
Logistic Analysis ◽  
Background Retinopathy ◽  
Potential Risk Factors ◽  
Auc Value

Background Retinopathy of prematurity (ROP) is the main causeof visual impairment in premature infants. Due to advances inneonatal care, the increased survival of extremely low birth weight(ELBW) infants in recent years has produced a population ofinfants at very high risk of ROP.Objective The aims of this study were to determine theprevalence and potential risk factors for ROP.Methods This retrospective study was conducted at theNeonatalogy Ward, Cipto Mangunkusumo Hospital, fromJanuary 2005 to August 2010. We included all prematureinfants of gestational age (GA) < 37 weeks, body weight(BW) not exceeding 2000 grams, as well as those who hadeye examinations and complete medical records. Risk factorssuch as GA, BW, duration of oxygen (Oz) therapy, sepsis, andred blood cell (RBC) transfusion were analyzed using the Chi􀀻square and logistic regression tests. Pediatric ophthalmologistshad performed eye examinations on all infants. ROP was gradedaccording to the International Classification of ROP.Results The prevalence of ROP and of stage 3 or greaterROP was 11.9% and 4.8% of all subjects, respectively. Bodyweight, GA, duration of Oz therapy, and sepsis were found tobe associated with the development ofROP. However, stepwiselogistic regression analysis revealed that only BW of:s 1000g [odds ratio (OR) 10.88; 95% CI 3.09 to 38.31; P < 0.000],02 therapy 2: 7 days (OR 5.56; 95% CI 1.86 to 16.58; P <0.0001), and GA of oS 28 weeks (OR 4.26; 95% CI 1.15 to15.81; P = 0.030) were statistically significant risk factors forROP. The equation obtained was y 􀀃 -4.092 + 2.388 (BW)+ 1.451 (GA) + 1.716 (duration of 02 therapy). The modelshowed good calibration (a non􀀻significant Hosmer􀀻Lemeshowtest; P = 0.816) and discriminative ability. The area underthe curve (AUC) value was 92.2% (95% CI 0.867 to 0.976;P < 0.0001).Conclusion Prevalence ofROP in this study (11.9%) was lowerthan that of previous studies. By regression logistic analysis, themain risk factors for development ofROP were BW of:s 1000g, Oz therapy 2: 7 days, and GA :s 28 weeks. The probability ofROP occurrence increased v.ith greater number of risk factors.[Paediatr rndones. 2012;52:138-44].

scholarly journals Risk factors for mortality in children with Wilms tumor

2016 ◽  
Vol 56 (4) ◽  
pp. 226
Author(s):  
Yuni Purwanti ◽  
Sutaryo Sutaryo ◽  
Sri Mulatsih ◽  
Pungky Ardani Kusuma
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Wilms Tumor ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Stage Iii ◽  
Control Group ◽  
Case Group ◽  
Chi Square ◽  
Potential Risk Factors

Background Wilms tumor is the most common renal malignancy in children (95%) and one of the leading causes of death in children, with high mortality rates in developing countries. Identifying risk factors for mortality is important in order to provide early intervention to improve cure rates.Objective To identify risk factors for mortality in children with Wilms tumor.Methods We performed a case-control study of children (0-18 years of age) with Wilms tumor admitted to Dr. Sardjito Hospital between 2005 and 2012. The case group consisted of children who died of Wilms tumor, whereas the control group were children who survived. Data were collected from medical records. Statistical analyses using Chi-square and logistic regression tests were done to determine odds ratios and 95% CI of the potential risk factors for mortality from Wilms tumor.Results Thirty-five children with Wilms tumor were admitted to Dr. Sardjito Hospital during the study period. Nine (26%) children died and 26 survived. Stage ≥III was a significant risk factor for mortality in chidren with Wilms tumor (OR 62.8; 95%CI 5.6 to 70.5). Age ≥2 years (OR 1.4; 95%CI 0.1 to 14.3) and male sex (OR 1.2; 95%CI 0.1 to 10.8) were not significant risk factors for mortality.Conclusion Stage ≥III is a risk factor for mortality in children with Wilms tumor. 

scholarly journals PREVALENCE OF HBV AND HCV; AND THEIR ASSOCIATED RISK FACTORS AMONG PUBLIC HEALTH CENTER CLEANERS AT SELECTED PUBLIC HEALTH CENTERS IN SANA'A CITY-YEMEN

2018 ◽  
Author(s):  
Waleed Hasan Mohammed AL-Marrani ◽  
Hassan A. Al-Shamahy
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Health Center ◽  
Venous Blood ◽  
Significant Risk ◽  
Chi Square ◽  
Cross Sectional ◽  
Hbv Vaccine ◽  
Public Health Center ◽  
Potential Risk Factors

Occupational exposure of public health center cleaners (PHCCs) to blood and body fluids after skin injury or mucous membrane contact constitutes a risk for transmission of blood-borne pathogens. In the industrialized world, occupational surveillance is performed to assess and monitor health hazards related to blood borne pathogens. In contrast, in developing countries as Yemen, exposure and health impacts are rarely monitored and much remains to be done to protect PHCCs. The objective of this study was to determine the prevalence of HBV and HCV and their potential risk factors among PHCCs.  A cross sectional prospective study was conducted among 388 PHCCs. Data was collected using pre-tested and structured questions. Venous blood was collected and the sera were tested for HBV surface antigen and anti-hepatitis C antibodies using enzyme-linked immune sorbent assay technique. The data were analysis by EPI-Info. Chi square and Odds ratio tests were used to assess the association of risk factors with HBV and HCV positivity. Results revealed that among the total 388 PHCCs examined, HBV and HCV were detected in 32 (8.2%), and 4 (1.03%) of them respectively.  There was significant risk factors of hepatitis viruses with age group 20-24 years (OR=2.8), exposure to patients blood (OR=3), accidental stick of used needles (OR=2.3), sharp injury (OR=5.6), history of blood transfusion (OR=2.5), and hospital admission (OR=2.7). Also significant protected roles for HBV vaccine was found with infection. In conclusion high prevalence rates of HBV and HCV occurred in PHCCs. Unfortunately; all workers did not take training on medical waste and few workers use protective measures consistently as vaccination. There is needed to make vaccination of health care workers against HBV infection a firm policy and ensure complete and consistent adherence to work standard safety measures.

scholarly journals Risk factors for relapse in pediatric nephrotic syndrome

2018 ◽  
Vol 58 (5) ◽  
pp. 238-41 ◽  
Author(s):  
Husein Albar ◽  
Fadel Bilondatu ◽  
Dasril Daud
Keyword(s):  
Risk Factors ◽  
Nephrotic Syndrome ◽  
Risk Factor ◽  
Nutritional Status ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Chi Square ◽  
Female Ratio ◽  
High Relapse Rate ◽  
Potential Risk Factors

Background Nephrotic syndrome (NS) is the most common kidney disease in children and is characterized by edema, massive proteinuria, hypoalbuminemia, and hyperlipidemia. High relapse rate remains a major problem in the management of this syndrome. Objective To identify risk factors for relapse in pediatric nephrotic syndrome. Methods This study was carried out in the Wahidin Sudirohusodo Teaching Hospital in Makassar, South Sulawesi, Indonesia, from January to August 2017 using complete medical records of children diagnosed with NS. Subjects were divided into 2 groups: 1) relapsed NS or 2) non-relapsed NS.  The following potential risk factors for relapse were analyzed using Chi-square test: age, sex, nutritional status, hypertension, serum creatinine level, and infection at the time of established diagnosis of NS. Results A total of 142 children with NS who fulfilled the inclusion criteria aged 1.4 to 17.5 years were included in the study. Subjects were mostly boys (66.2%), with a male: female ratio of 1.95:1. The relapsed NS group had 80 cases (56.3%) and the non-relapsed NS group had 62 cases (43.7%). Statistical analysis revealed that nutritional status was a significant risk factor for relapse in pediatric nephrotic syndrome (P<0.05). Conclusion Nutritional status is an independent risk factor for relapse in pediatric nephrotic syndrome. 

scholarly journals MO829INSTITUTIONAL TRANSPORT AS RISK FACTOR FOR COVID-19 IN HEMODIALYSIS PATIENTS

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Line Heylen ◽  
Margaretha Van Kerrebroeck ◽  
Els Oris ◽  
Liesbet Hendrickx ◽  
Eline Macken ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Hemodialysis Patients ◽  
Nasopharyngeal Swab ◽  
Prevention Measures ◽  
Chi Square ◽  
Dialysis Unit ◽  
Potential Risk Factors

Abstract Background and Aims Hemodialysis patients face an exceptional risk in the current COVID19 pandemic, both for infection/transmission as well as for mortality. All efforts to reduce potential risk factors are needed to protect this vulnerable group. We aimed to evaluate risk factors for SARS-CoV-2 infection and transmission during the first COVID19 wave, in order to tackle these factors in the second. Method We included all hemodialysis patients who were dialyzed at our central institution on March 19, 2020 (date of first COVID19 diagnosis). External low care and home hemodialysis patients were excluded. Our central hemodialysis center has 5 dialysis shifts in 6 units located next to each other, with a separate seventh dialysis unit dedicated for COVID19 isolation. COVID19 infections were diagnosed with nasopharyngeal swab PCR at the discretion of the treating nephrologist. On May 18 and 19, after the first wave, all hemodialysis patients were evaluated for presence of SARS-CoV-2 antibodies using ELISA to screen for previous asymptomatic infections. Chi square and logistic regression were used for statistical analyses. Results 216 hemodialysis patients were included in this study, with a mean age of 72 years old (IQR 65-83). COVID19 was diagnosed in 17 patients during the first wave: in 15 symptomatic cases through nasopharyngeal swab PCR and in two additional asymptomatic cases through SARS-CoV-2 IgG positivity. Interestingly, we observed that 58.8% of COVID19 patients were transported by the same transport company, while this company transports only 20.4% of hemodialysis patients (p=0.005) (Figure A). As such, 22.7% of patients transported by this company became infected (OR 6.93, 95% CI 2.49-20.34, p=0.0002). Conclusion Institutional transport was the most significant risk factor for SARS-CoV-2 infection among hemodialysis patients at our center. After stringent prevention measures we were able to prevent transmission during transport in the second wave of the COVID19 pandemic.

Stratifying the risk of facial nerve palsy after benign parotid surgery

2014 ◽  
Vol 128 (2) ◽  
pp. 159-162 ◽  
Author(s):  
N Sethi ◽  
P H Tay ◽  
A Scally ◽  
S Sood
Keyword(s):  
Risk Factors ◽  
Facial Nerve ◽  
Facial Palsy ◽  
Significant Risk ◽  
Chi Square ◽  
Nerve Monitoring ◽  
Facial Nerve Monitoring ◽  
Parotid Surgery ◽  
Potential Risk Factors ◽  
Chi Square Test

AbstractIntroduction:Post-operative facial palsy is the most important potential complication of parotid surgery for benign lesions. The published prevalence of facial weakness is up to 57 per cent for temporary weakness and up to 7 per cent for permanent weakness. We aimed to identify potential risk factors for post-operative facial palsy.Materials and methods:One hundred and fifty patients who had undergone parotid surgery for benign disease were retrospectively reviewed. Tumour factors (size, location and histopathology), patient factors (age and sex) and operative factors (operation, surgeon grade, surgeon specialty and use of intra-operative facial nerve monitoring) were all analysed for significant associations with post-operative facial palsy.Results and analysis:The overall incidence of facial palsy was 26.7 per cent for temporary weakness and 2.6 per cent for permanent weakness. The associations between facial palsy and all the above factors were analysed using Pearson's chi-square test and found to be non-significant.Conclusion:These outcomes compare favourably with the literature. No significant risk factors were identified, suggesting that atraumatic, meticulous surgical technique is still the most important factor affecting post-operative facial palsy.

Venous Thromboembolism and High Grade Gliomas

1993 ◽  
Vol 70 (03) ◽  
pp. 393-396 ◽  
Author(s):  
Mandeep S Dhami ◽  
Robert D Bona ◽  
John A Calogero ◽  
Richard M Hellman
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Medical Center ◽  
Significant Risk ◽  
Bleeding Complications ◽  
Fisher Exact Test ◽  
High Grade ◽  
Chi Square ◽  
Exact Test ◽  
High Grade Gliomas

SummaryA retrospective study was done to determine the incidence of and the risk factors predisposing to clinical venous thromboembolism (VTE) in patients treated for high grade gliomas. Medical records of 68 consecutive patients diagnosed and treated at Saint Francis Hospital and Medical Center from January 1986 to June 1991 were reviewed. The follow up was to time of death or at least 6 months (up to December 1991). All clinically suspected episodes of VTE were confirmed by objective tests. Sixteen episodes of VTE were detected in 13 patients for an overall episode rate of 23.5%. Administration of chemotherapy (p = 0.027, two tailed Fisher exact test) and presence of paresis (p = 0.031, two tailed Fisher exact test) were statistically significant risk factors for the development of VTE. Thrombotic events were more likely to occur in the paretic limb and this difference was statistically significant (p = 0.00049, chi square test, with Yates correction). No major bleeding complications were seen in the nine episodes treated with long term anticoagulation.We conclude that venous thromboembolic complications are frequently encountered in patients being treated for high grade gliomas and the presence of paresis and the administration of chemotherapy increases the risk of such complications.

scholarly journals Risk Factors Associated with Retinopathy of Prematurity in Very and Extremely Preterm Infants

Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 420
Author(s):  
Claudia Ioana Borțea ◽  
Florina Stoica ◽  
Marioara Boia ◽  
Emil Radu Iacob ◽  
Mihai Dinu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preterm Infants ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Univariate Analysis ◽  
Significant Risk ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Surfactant Administration ◽  
Stage 1

Background and Objectives: Retinopathy of prematurity (ROP) is the leading cause of blindness in preterm infants. We studied the relationship between different perinatal characteristics, i.e., sex; gestational age (GA); birth weight (BW); C-reactive protein (CRP) and lactate dehydrogenase (LDH) concentrations; ventilation, continuous positive airway pressure (CPAP), and surfactant administration; and the incidence of Stage 1–3 ROP. Materials and Methods: This study included 247 preterm infants with gestational age (GA) < 32 weeks that were successfully screened for ROP. Univariate and multivariate binary analyses were performed to find the most significant risk factors for ROP (Stage 1–3), while multivariate multinomial analysis was used to find the most significant risk factors for specific ROP stages, i.e., Stage 1, 2, and 3. Results: The incidence of ROP (Stage 1–3) was 66.40% (164 infants), while that of Stage 1, 2, and 3 ROP was 15.38% (38 infants), 27.53% (68 infants), and 23.48% (58 infants), respectively. Following univariate analysis, multiple perinatal characteristics, i.e., GA; BW; and ventilation, CPAP, and surfactant administration, were found to be statistically significant risk factors for ROP (p < 0.001). However, in a multivariate model using the same characteristics, only BW and ventilation were significant ROP predictors (p < 0.001 and p < 0.05, respectively). Multivariate multinomial analysis revealed that BW was only significantly correlated with Stage 2 and 3 ROP (p < 0.05 and p < 0.001, respectively), while ventilation was only significantly correlated with Stage 2 ROP (p < 0.05). Conclusions: The results indicate that GA; BW; and the use of ventilation, CPAP, and surfactant were all significant risk factors for ROP (Stage 1–3), but only BW and ventilation were significantly correlated with ROP and specific stages of the disease, namely Stage 2 and 3 ROP and Stage 2 ROP, respectively, in multivariate models.

scholarly journals Risk Factors for Retinopathy of Prematurity in the Netherlands: A Comparison of Two Cohorts

Neonatology ◽  
2021 ◽  
pp. 1-8
Author(s):  
Kasia Trzcionkowska ◽  
Floris Groenendaal ◽  
Peter Andriessen ◽  
Peter H. Dijk ◽  
Frank A.M. van den Dungen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
The Netherlands ◽  
Retinopathy Of Prematurity ◽  
Screening Guideline ◽  
Potential Risk Factors ◽  
Second Period ◽  
Perinatal Database ◽  
Rop Screening

<b><i>Introduction:</i></b> Retinopathy of prematurity (ROP) remains an important cause for preventable blindness. Aside from gestational age (GA) and birth weight, risk factor assessment can be important for determination of infants at risk of (severe) ROP. <b><i>Methods:</i></b> Prospective, multivariable risk-analysis study (NEDROP-2) was conducted, including all infants born in 2017 in the Netherlands considered eligible for ROP screening by pediatricians. Ophthalmologists provided data of screened infants, which were combined with risk factors from the national perinatal database (Perined). Clinical data and potential risk factors were compared to the first national ROP inventory (NEDROP-1, 2009). During the second period, more strict risk factor-based screening inclusion criteria were applied. <b><i>Results:</i></b> Of 1,287 eligible infants, 933 (72.5%) were screened for ROP and matched with the Perined data. Any ROP was found in 264 infants (28.3% of screened population, 2009: 21.9%) and severe ROP (sROP) (stage ≥3) in 41 infants (4.4%, 2009: 2.1%). The risk for any ROP is decreased with a higher GA (odds ratio [OR] 0.59 and 95% confidence interval [CI] 0.54–0.66) and increased for small for GA (SGA) (1.73, 1.11–2.62), mechanical ventilation &#x3e;7 days (2.13, 1.35–3.37) and postnatal corticosteroids (2.57, 1.44–4.66). For sROP, significant factors were GA (OR 0.37 and CI 0.27–0.50), SGA (OR 5.65 and CI 2.17–14.92), postnatal corticosteroids (OR 3.81 and CI 1.72–8.40), and perforated necrotizing enterocolitis (OR 7.55 and CI 2.29–24.48). <b><i>Conclusion:</i></b> In the Netherlands, sROP was diagnosed more frequently since 2009. No new risk factors for ROP were determined in the present study, apart from those already included in the current screening guideline.

Post-Bariatric Abdominoplasty: Analysis of 406 Cases With Focus on Risk Factors and Complications

2020 ◽  
Vol 41 (1) ◽  
pp. 59-71 ◽  
Author(s):  
Torsten Schlosshauer ◽  
Marcus Kiehlmann ◽  
Diana Jung ◽  
Robert Sader ◽  
Ulrich M Rieger
Keyword(s):  
Risk Factors ◽  
Wound Healing ◽  
Surgical Technique ◽  
Significant Risk ◽  
Level Of Evidence ◽  
Increased Risk ◽  
Potential Risk Factors ◽  
Wound Healing Problems ◽  
Bariatric Patients

Abstract Background Post-bariatric patients present a surgical challenge within abdominoplasty because of residual obesity and major comorbidities. In this study, we analyzed complications following abdominoplasty in post-bariatric patients and evaluated potential risk factors associated with these complications. Objectives The authors sought to determine the complications and risk factors following abdominoplasty in post-bariatric patients. Methods A retrospective study of patients who underwent abdominoplasty was performed from January 2009 to December 2018 at our institution. Variables analyzed were sex, age, body mass index (BMI), smoking, surgical technique, operative time, resection weight, drain output, and complications. Results A total of 406 patients were included in this study (320 female and 86 male) with a mean age of 44.4 years and a BMI of 30.6 kg/m2. Abdominoplasty techniques consisted of traditional (64.3%), fleur-de-lis technique (27.3%), and panniculectomy without umbilical displacement (8.4%). Overall complications recorded were 41.9%, the majority of these being wound-healing problems (32%). Minor and major complications were found in 29.1% and 12.8% of patients, respectively. A BMI value of ≥30 kg/m2 was associated with an increased risk for wound-healing problems (P = 0.001). The frequency of total complications was significantly related to age (P = 0.007), BMI (P = 0.004), and resection weight (P = 0.001). Abdominoplasty technique tended to influence total complications. Conclusions This study demonstrates in a fairly large sample of post-bariatric patients (n = 406) that abdominoplasty alone can be performed safely, with an acceptable complication rate. Age, BMI, and resection weight are shown to be significant risk factors for total complications. The role of surgical technique needs to be evaluated further. Level of Evidence: 4

Prevalence of Human Cystic Echinococcosis in Rio Negro Province, Argentina and Direct Risk Factors for Infection

2021 ◽  
Author(s):  
Leonardo Uchiumi ◽  
Guillermo Mujica ◽  
Daniel Araya ◽  
Juan Carlos Salvitti ◽  
Mariano Sobrino ◽  
...  
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Rural Areas ◽  
Cystic Echinococcosis ◽  
Significant Risk ◽  
Prevalence Ratio ◽  
Bivariate Analysis ◽  
Rio Negro ◽  
Potential Risk Factors ◽  
Current Address

Abstract Background: Cystic echinococcosis (CE) is a parasitic zoonosis caused by infection with the larval stage of Echinococcus granulosus sensu lato This study investigated the prevalence and potential risk factors associated with human CE in the towns and rural areas of Ñorquinco and Ramos Mexia, Rio Negro province, Argentina. Methods: In order to detect abdominal CE cysts, we screened 892 volunteers by ultrasound and investigated potential risk factors for CE using a standardized questionnaire. Bivariate and multivariate analyses were used to estimate the Prevalence Ratio (PR) and their 95% CIs of the association between CE and the factors investigated. Results: Abdominal CE was detected in 42/892 screened volunteers (4.7%, CI 3.2-6.1), only two of who being under 15 years of age. Thirteen CE (30.9%) cases had 25 cysts in active stages (CE1, CE2, CE3) The most relevant risk factors identified in the bivariate analysis included: live in rural area (p=0.003), age >40 years (p=0.000), drinking always water of natural source (p=0.007), residing in rural areas during first five years of life (p=0.000) and live more than 20 years at your current address (p=0.013). In the multivariate model, statistically significant risk factors were: frequently touch dogs (p=0.012), residing in rural areas during first five years of life (p=0.004), smoking (p=0.000), age > 60 years (p­­=0.002) and live in rural areas (p=0.017).Conclusions: our results point toward infection with CE being acquired since childhood and with constant exposure throughout life, especially in rural areas with a general environmental contamination

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