scholarly journals Proteinuria and malaria parasite counts in children

2013 ◽  
Vol 53 (6) ◽  
pp. 295 ◽  
Author(s):  
Mahrani Lubis ◽  
Rusdidjas Rusdidjas ◽  
Rafita Ramayati ◽  
Oke Rina Ramayani ◽  
Rosmayanti S Siregar ◽  
...  
Keyword(s):  
Malaria Parasite ◽  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Urine Dipstick ◽  
Weak Association ◽  
Blood Smears ◽  
Moderate Malnutrition ◽  
Peripheral Blood Smears

Background Malaria-induced proteinuria has been observed insevere cases of malaria. Few studies have been done to assess foran association between proteinuria and malaria parasite countsbefore the disease becomes severe.Objective To investigate a possible association between proteinuriaand malaria parasite counts in children .Methods A cross-sectional study was conducted on school-agedchildren in Panyabungan, Mandailing Natal, between Septemberto November 2010. Malaria was diagnosed by microscopicexamination of peripheral blood smears. Children with malariaunderwent proteinuria t ests by urine dipstick method. Anassociation between proteinuria and malaria parasite counts wasanalyzed using linear regression test.Results Of 181 participants with Plasmodium fak:iparum malaria,53.6% were female and had a mean age of 7.8 years. Subjects'nutritional status were as follows: 50.8% normoweight, 28.2%mild malnutrition, 3 .3% moderate malnutrition, and 17. 7% severemalnutrition. Clinical manifestations showed 36.5% suffered fromsubfebrile temperatures and 29.8% had pallor. Proteinuria occurredin 45.9% participants and there was a weak association betweenproteinuria and malaria parasite counts (raa .261, Paa .0001).Conclusion There is a weak association between proteinuria andmalaria parasite counts in children.

scholarly journals Seroprevalence of Canine Ehrlichiosis and Microscopic Screening for Canine Babesiosis in Dogs in Harare, Zimbabwe, 2016-2017

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Solomon Dhliwayo ◽  
Brighton Chihambakwe ◽  
Knowledge Taonezvi ◽  
Silvester M. Chikerema ◽  
Musavengana T. Tivapasi ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Sectional Study ◽  
Canine Babesiosis ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Canine Ehrlichiosis ◽  
Blood Smears ◽  
Peripheral Blood Smears ◽  
Common Laboratory

A cross-sectional study was done to determine ehrlichiosis seroprevalence and babesiosis prevalence in dogs that were presented to selected veterinary clinics in Harare. Sera from randomly selected dogs were tested for antibodies to Ehrlichia spp. using an enzyme-linked immunosorbent assay while microscopy of peripheral blood smears was used to confirm babesiosis. Overall, 75.2% (88/117, 95% CI: 66.2–82.5) of sera samples tested were positive to Ehrlichia spp. antibodies while the prevalence of canine babesiosis was 47.9% (56/117, 95% CI: 38.6–57.3). Age, breed, and sex were found not to be associated with the two disease conditions p>0.05. Most of the dogs with babesiosis (82.1%, 46/56) were also positive to Ehrlichia spp. antibodies. Hypoalbuminaemia (53.8%, 63/117), anaemia (53.0%, 62/117) and thrombocytopaenia (40.2%, 47/117) were the most common laboratory findings. Thrombocytopaenia and hypoalbuminaemia was more pronounced in dogs with babesiosis only while anaemia was more marked in dogs with babesiosis and positive to Ehrlichia spp. antibodies.

Etiologies, Clinical Manifestations, and Factors Associated with Severe Symptomatic Hyponatremia among Hospitalized Hyponatremia Patients

2020 ◽  
Vol 103 (5) ◽  
pp. 465-471
Keyword(s):  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
Hospitalized Patients ◽  
Sectional Study ◽  
Close Attention ◽  
Cross Sectional ◽  
Factors Associated ◽  
Present Cross Sectional Study ◽  
Important Health ◽  
Baseline Characteristics

Background: Hyponatremia is associated with unfavorable outcomes in many cases. The mainstay of hyponatremia treatment depends on its symptoms and etiology. However, etiologies, clinical manifestations, and factors associated with severe symptomatic hyponatremia have been rarely reported. Objective: To analyze and report etiologies, clinical manifestations, and factors associated with severe symptomatic hyponatremia. Materials and Methods: In the present cross-sectional study, the authors enrolled hospitalized patients with hyponatremia who had consulted a nephrologist between October 1, 2017, and October 31, 2018. Their baseline characteristics and clinical manifestations were recorded. Etiologies were confirmed by the attending nephrology staff. Factors associated with severe symptomatic hyponatremia were evaluated using logistic regression analysis. Results: One hundred patients were included in this study. The syndrome of inappropriate antidiuresis (SIAD), hypovolemia, and hydrochlorothiazide use were the leading hyponatremia etiologies. Hyponatremia etiologies differed between patients with community-acquired hyponatremia (n=50) and those with hospital-associated hyponatremia (n=50). Patients with communityacquired hyponatremia were older, presented with a higher frequency of severe symptomatic hyponatremia, and showed lower SNa-levels. Low SNa-levels were significantly associated with severe symptomatic hyponatremia (p=0.014). Conclusion: Hyponatremia remains an important health problem. SIAD, hypovolemia, and hydrochlorothiazide use are among the leading etiologies of hyponatremia. Low SNa-levels are associated with severe symptomatic hyponatremia; thus, physicians should pay close attention to low SNa-levels in hospitalized patients. Keywords: Hyponatremia, Symptomatic Hyponatremia, Community-acquired hyponatremia, Hospital-associated hyponatremia

Clinical manifestations, risk factors and quality of life in patients with pitted keratolysis: a cross-sectional study in cadets

2018 ◽  
Vol 179 (5) ◽  
pp. 1220-1221 ◽  
Author(s):  
S. Bunyaratavej ◽  
C. Leeyaphan ◽  
P. Chanyachailert ◽  
P. Pattanaprichakul ◽  
P. Ongsri ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Risk factors of developing Pneumonia Among Confirmed Measles Cases

2018 ◽  
Vol 52 (4) ◽  
Author(s):  
Michelle C. Ylade
Keyword(s):  
Risk Factors ◽  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
The Philippines ◽  
Measles Vaccine ◽  
Sectional Study ◽  
Cross Sectional ◽  
Younger Age ◽  
Potential Risk Factors ◽  
Measles Outbreaks

Background. Deaths may occur due to complications of measles. The most common measles complication is pneumonia and accounts for most measles-related deaths. Objective. The study aimed to identify risk factors for developing pneumonia among measles cases. Methodology. A cross-sectional study was conducted using measles surveillance data from an outbreak in the Philippines from January 2013 to December 2014. Data on age, sex, area of residence, clinical manifestations, receipt of measles vaccine, and other exposure variables were obtained and analyzed using logistic regression. Results. Approximately 25,166 confirmed measles cases were included in the study where 16% had pneumonia. Potential risk factors identified in the development of pneumonia among confirmed measles cases were younger age (<5 years = OR 2.49, 95% CI: 1.81,3.42; 5-14 years = OR 2.34, 95% CI: 1.64,3.33), resident of Mindanao (OR 2.18, 95% CI: 1.74,2.74), presence of cough (OR 5.51, 95% CI: 2.04,14.86), presence of conjunctivitis (OR 1.31, 95% CI: 1.11,1.55), and being admitted to hospital (OR 3.16, 95% CI: 2.57,3.90). Confirmed measles cases with receipt of measles containing vaccine (MCV) (OR 0.74, 95% CI: 0.63,0.87) were found to be less likely to have pneumonia. Conclusion. These risk factors help identify cases requiring prompt management to reduce morbidity and mortality in any future measles outbreaks.

scholarly journals Feasibility of Asynchronous and Automated Telemedicine in Otolaryngology: Prospective Cross-Sectional Study

10.2196/23680 ◽  
2020 ◽  
Vol 8 (10) ◽  
pp. e23680
Author(s):  
Dongchul Cha ◽  
Seung Ho Shin ◽  
Jungghi Kim ◽  
Tae Seong Eo ◽  
Gina Na ◽  
...  
Keyword(s):  
Medical Records ◽  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
Interrater Agreement ◽  
Diagnostic Model ◽  
Sectional Study ◽  
Perfect Agreement ◽  
Cross Sectional ◽  
Machine Learning Model ◽  
Community Transmission

Background COVID-19 often causes respiratory symptoms, making otolaryngology offices one of the most susceptible places for community transmission of the virus. Thus, telemedicine may benefit both patients and physicians. Objective This study aims to explore the feasibility of telemedicine for the diagnosis of all otologic disease types. Methods A total of 177 patients were prospectively enrolled, and the patient’s clinical manifestations with otoendoscopic images were written in the electrical medical records. Asynchronous diagnoses were made for each patient to assess Top-1 and Top-2 accuracy, and we selected 20 cases to conduct a survey among four different otolaryngologists to assess the accuracy, interrater agreement, and diagnostic speed. We also constructed an experimental automated diagnosis system and assessed Top-1 accuracy and diagnostic speed. Results Asynchronous diagnosis showed Top-1 and Top-2 accuracies of 77.40% and 86.44%, respectively. In the selected 20 cases, the Top-2 accuracy of the four otolaryngologists was on average 91.25% (SD 7.50%), with an almost perfect agreement between them (Cohen kappa=0.91). The automated diagnostic model system showed 69.50% Top-1 accuracy. Otolaryngologists could diagnose an average of 1.55 (SD 0.48) patients per minute, while the machine learning model was capable of diagnosing on average 667.90 (SD 8.3) patients per minute. Conclusions Asynchronous telemedicine in otology is feasible owing to the reasonable Top-2 accuracy when assessed by experienced otolaryngologists. Moreover, enhanced diagnostic speed while sustaining the accuracy shows the possibility of optimizing medical resources to provide expertise in areas short of physicians.

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