scholarly journals Association of body mass index with atopy and allergic diseases

2016 ◽  
Vol 56 (4) ◽  
pp. 221
Author(s):  
Afnita Lestary ◽  
Lily Irsa ◽  
Tiangsa Sembiring ◽  
Rita Evalina ◽  
Meiviliani Sinaga

Background Prevalence of atopy, allergic diseases, and obesity are increasing. Atopy is an individu and/or familial tendency to sensitization in response to ordinary exposure to allergens. Obesity is defined as body mass index (BMI) greater or equal to 95 percentile. Research on association of BMI with atopy and allergic diseases in children were limited, with inconclusive results. Objective To assess association of BMI with atopy and allergic diseases in chidren.Methods A cross-sectional was conducted in school children aged 6-12 years in Lhokseumawe City, Aceh, June 2012. Children were assessed for BMI, skin prick test, and  International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. Statistical analyses included Chi-square, Fisher exact, and logistic regression.Results Children consisted of 137 (85.6%) normoweight, 12 (7.5%) overweight, and 11 (6.9%) obesity. Skin prick test results were positive in 44 (27.5%) and negative in 116 (72.5%) subjects. Allergic manifestations were allergic rhinitis (AR) 17 (10.6%), bronchial asthma 6 (3.8%), and atopic dermatitis (AD) 3 (1.9%). There was significant association of obesity with atopy, compared with normoweight (OR=3.78; 95%CI 1.08 to 13.19; P=0.037), but no significant association found when family history of atopy also assesed. There was significant association of obesity with bronchial asthma (OR=9.92; 95%CI 1.46 to 67.18; P=0.004) and AR (OR=6.49; 95%CI 1.64 to 25.66; P=0.015), compared with normoweight. Significant association of overweight with atopy and allergic disease was not found.Conclusion Obesity significantly associates with atopy, bronchial asthma, and AR, but overweight and normoweight  do not.  

2014 ◽  
Vol 54 (1) ◽  
pp. 52
Author(s):  
Schenny Regina Lubis ◽  
Lily Lrsa ◽  
Rita Evalina ◽  
Supriatmo Supriatmo ◽  
M. Sjabaroeddin

Background Allergic diseases cause an increasingly largeburden in developed countries and in urban areas of middleincomecountries . Paras itic infections may induce allergicresponses in humans, particularly soil-transmitted helminth(STH) infections that are prevalent in childhood in developingcountries. Although soil-transmitted helminth infec tions havebeen associated with lower prevalence of allergen skin testreactivity, study outcomes remain inconclusive.Objective To analyze for an association between STH infectionsand skin prick test reactivity in children.Methods We conducted a cross-sectional study in August 2009among primary school students aged 7- 12 years, at SecanggangSubdistrict, Langkat District, North Sumatera Province. Sixtyeight children were recruited in this study consisted of 34 childrenwith STH infections and the other 34 children without any STHinfection. Soil-transmitted helminth infections were determinedby Kato-Katz stool examination s. All subjects underwent skinprick tests for seven allergens. Results were con sidered to bepositive if wheal diameters 2: 3 mm and negative when whealdiameters < 3 mm. Data was an alysed by Chi-square test.Results Stool examinations revealed that the most commoninfec tion was T. trichiura (18/34 subjects), followed by mixedinfections (T. trichiura and A lumbricoides; 12/34 subjects), andA. lumbricoides (4134 subjects). There was a significant associationbetween STH infections and negative skin prick test (P= 0.002).In addition, there were significant associations with negative skinprick tests for each helminth type: A. lumbricoides (P=0.001) ,T. trichiura (P=0.01) and mixed infection (P = 0.006). Severeinfection intensity was also significantly associated with negativeskin prick tests (P=0.031) .Conclusion Children with STH infections tend to have negativeskin prick test results.


2015 ◽  
Vol 55 (4) ◽  
pp. 189
Author(s):  
Beatrix Siregar ◽  
Lily Irsa ◽  
Supriatmo Supriatmo ◽  
Sjabaroeddin Loebis ◽  
Rita Evalina

Background Some studies have shown that low birth order is a risk factor for developing atopy, although these results remain inconclusive. Those studies put forth the hygiene hypothesis, which states that early childhood infections in siblings may protect against atopy. Hence, an inverse relationship between family numbers and atopy was found. Atopy may be diagnosed from a history of atopy in an individual or his family, and can be confirmed by specific IgE for allergens or positive skin prick tests.Objective To assess for an association between skin prick test reactivity in atopic children and their number of siblings.Methods A cross-sectional study was conducted in May to June 2010 in elementary school children at the Kampung Baru District, Medan Regency, North Sumatera. Subjects were divided into two groups. Group I had children with < 3 siblings and group II had children with ≥ 3 siblings. Skin prick tests were done in 7 to 10-year-old children with a history of asthma, allergic rhinitis and atopic dermatitis. Skin prick test reactivity results were analyzed by Chi-square test.Results A total of 192 subjects were enrolled in this study, with 96 subjects in each group. Positive skin prick tests were significantly higher in subjects with <3 siblings than in those with >3 siblings (75% and 53.1%, respectively; P=0.003).Conclusion Atopic children with <3 siblings had more positive skin prick tests than children with >3 siblings.


Author(s):  
Mounika K. ◽  
Shivaswamy K. N.

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Urticaria is an allergic skin disorder characterized by wheals. Though the diagnosis is easy, it is difficult to identify the cause for the episodes. Autologous serum skin test (ASST) and skin prick test (SPT) help in the identification of the cause. The objective of the study was to determine the frequency of ASST and SPT positivity in patients with chronic idiopathic urticaria (CIU).</span></p><p class="abstract"><strong>Methods:</strong> Fifty-six patients attending the dermatology OPD with chronic idiopathic urticaria were evaluated and taken up for the study. ASST and SPT were performed on all the patients and the obtained results were documented. Data was analyzed using Chi square test.<strong></strong></p><p class="abstract"><strong>Results:</strong> Among the 56 patients studied, males (53.57%) outnumbered females and the majority was in the age group 21 to 30 years (33.9%). One third of the study patients gave history of known food allergy and 10.7% gave history of dust allergy. ASST positivity was seen in 30.3% and SPT positivity was seen in 64.3%. Ten of our patients (17.8%) were positive to both ASST and SPT. Amongst the SPT positives 33.3% showed positivity to food allergens, 19.4% showed positivity to aeroallergens and 47.2% showed positivity to both<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> ASST and SPT are two reliable tools in identifying the cause for urticaria and this in turn helps in avoidance of possible causes and providing proper treatment<span lang="EN-IN">.</span></p>


2020 ◽  
Vol 3 (2) ◽  
pp. 112-119
Author(s):  
Hafizd Komar ◽  
Hero Akbar ◽  
Theodorus

Abstract Laparoscopic cholecystectomy is the gold standard for cholecystectomy and can be performed by trained general surgeons. However, the percentage of complications that occur from cholecystectomy laparotomy is approximately 20 percent. So, it is necessary to research risk factors for complications. This research is an analytic observational study with a cross-sectional design using preoperative data and intraoperative findings of laparoscopic cholecystectomy. Age, gender, body mass index, history of cholecystitis, number of stones, and location of stones are identified as predictors that affect the difficulty of laparoscopic cholecystectomy. The data collection was performed at the Mohammad Hoesin Hospital Palembang Department from July 2019- July 2020. Of the 67 research samples, a Chi-square test was performed, and the factors that had a significant relationship were the body mass index (P-Value 0,000), history of cholecystitis (P-Value 0,000), number of stones (P-Value 0.049), and stone location. (P-Value 0.002). The backward stepwise logistic regression using the four variables showed that the history of cholecystiti


2021 ◽  
Vol 11 (5) ◽  
pp. 410-419
Author(s):  
Agus Yudawijaya ◽  
Tranggono Yudo Utomo ◽  
Vanessa Destiana

Osteoarthritis is a chronic and degenerative disease characterized by pain and damage to joint cartilage, which often causes pain and limited movement in the elderly population to disrupt daily activities and cause severe socio-economic impacts. The risk factor is more than 50 years, female gender, obesity, history of knee trauma, and anatomical abnormalities. This study was conducted to determine the relationship between body mass index to the degree of genu osteoarthritis. The design of this study was observational analytic with a cross-sectional study approach, using consecutive sampling. The tools used are medical record paper, weight scales, staturmeter, X photo articulation genu. Parameters examined were gender, age, weight (BB), height (TB), grade osteoarthritis (OA) genu Kellgren-Lawrence. It is conducted at Tarakan Hospital, Jakarta. The results showed 67,5% of respondents were female, 67,5% of respondents with OA genu aged > 50 years, 67,5% of respondents with BMI ≥ 23, 17,5% OA genu with grade Kellgren-Lawrence 1, 22,5% OA genu with grade Kellgren-Lawrence 2, 30% OA genu with grade Kellgren-Lawrence 3 and 30% OA genu with Kellgren-Lawrence 4. Results of the chi-square test have a relationship between body mass index (p = 0.042) on the degree of osteoarthritis genu in Tarakan Hospital, Jakarta. It was concluded that there was a relationship between body mass index to the degree of osteoarthritis genu in Tarakan Hospital, Jakarta. Key words: Osteoarthritis, Body Mass Index, Grade OA Genu Kellgren-Lawrence.


2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Agus Suseno

Hubungan Antara Kejadian Osteoartritis Dengan Obesitas Yang Diukur Dengan Metode Pengukuran BMI. Latar Belakang. Badan Kesehatan Dunia (WHO) telah menyatakan bahwa obesitas telah menjadi epidemi dunia. Saat ini prevalensi penderitanya tiap tahun semakin meningkat. Obesitas merupakan salah satu faktor resiko osteoartritis, ditandai dengan kerusakan pada tulang rawan sendi yang berakhir dengan kerusakan ke seluruh sendi. Hingga kini belum ada obat yang pasti untuk menanggulangi penyakit osteoartritis. Pengobatan yang dilakukan selama ini hanya untuk menghilangkan rasa nyerinya saja. Tujuan Penelitian. Untuk mengetahui adanya hubungan antara kejadian osteoartritis pada penderita obesitas dengan menggunakan metode BMI. Metodologi Penelitian. Analitik observasional dengan pendekatan secara cross sectional. Sampel diambil secara random sampling melalui rekam medik rawat jalan bagian Rheumatologi Rumah Sakit Swasta Kota Malang periode Januari – Desember 2006. Untuk menentukan adanya hubungan osteoartritis dengan obesitas dilakukan uji hipotesis Chi Square dengan nilai signifikasi (p) lebih kecil dari alpha 0.05. Hasil Penelitian. Dari 125 sampel penelitian didapatkan 70,4% wanita dan prevalensi osteoartritis dengan obesitas 58,4%. Hasil uji chi square didapatkan adanya hubungan antara kejadian osteoartritis dengan obesitas menggunakan metode pengukuran body mass index yang ditunjukkan dengan nilai signifikasi (p) 0.035. Kesimpulan. Didapatkan hubungan yang bermakna antara kejadian osteoarthritis dengan obesitas menggunakan metode pengukuran body mass index.


2018 ◽  
Vol 34 (5-6) ◽  
pp. 129-35
Author(s):  
Hendra Santoso

Thirty children from infancy to 12 years suffering from atopic dermatitis were evaluated for food hypersensitivity by means of history, skin prick test, total eosinophils count, and elimination of suspected food. Sixteen (53%) patients had history of allergy to suspected food, the other 16 (53%) had ether allergic diseases. Of the 30 patients, 15 (50%) had one of the parents with allergic diseases, and in 3 patients both parents suffered from a1Iergic diseases. Nineteen (6:3-1.) children had atopic dermatitis triggered by food; egg accounted for 400/o, fish for 53-lo and shrimp for 40% for the allergic manifestations. Skin prick test consisted of 20 food allergens was done to all children above 2 years of age, 12 (40%) of the pa1ients showed positive results. This study demonstrated that food hypersensitivity may play a pathogenic role in some children with atopic dermatitis. Appropriate diagnosis and restriction of diet can improve their skin symptoms.


Author(s):  
Nasrin Pazoki ◽  
Ali Ahmadi ◽  
Fatemeh Onsori ◽  
Mohsen Mosavi Khorshidi ◽  
Mahboubeh Mansori ◽  
...  

Background and Aims: Identification of different allergens is a major challenge in allergic diseases. Avoiding these allergens is known as one of the best types of treatment. The aim of this study is to determine the prevalence of aeroallergens and food allergens in patients with allergy by Skin Prick Test. Materials and Methods: A cross-sectional study was conducted on 255 patients with allergic diseases who had referred to the Khorshid Allergy and Immunology Clinic. Skin Prick Test was performed using 82 allergen extracts to determine the patients' sensitivity to food and aeroallergens. Results: One hundred percent of the patients were sensitive to at least one allergen. Allergy to food allergens and aeroallergens was 49% and 51 %, respectively. Most sensitivity to food allergens included hazelnut (26.27%), bananas (21.96%), egg yolk (21.56%) and wheat (20.39%). Among the aeroallergens, grass with a frequency of 87% and fungi with a frequency of 34% had the highest and lowest frequencies. Conclusion: Depending on the nutrition, cultural habits, environmental conditions, and life style, prevalence of the allergens in each area may be different. Therefore, early identification and avoidance from these allergens can be suggested.


2020 ◽  
Vol 20 (3) ◽  
Author(s):  
Cici Enjelia Nata ◽  
Safrizal Rahman ◽  
Sakdiah Sakdiah

Abstrak. Indeks Massa Tubuh (IMT) merupakan parameter yang digunakan untuk menilai komposisi tubuh dengan menggunakan klasifikasi Asia Pasifik. IMT menjadi salah satu faktor risiko terjadinya osteoartritis lutut. Osteoartritis lutut merupakan penyakit degeneratif yang terjadi pada sendi lutut. Berdasarkan RISKESDAS tahun 2018, Provinsi Aceh menduduki peringkat pertama sebagai provinsi dengan angka penyakit sendi terbanyak yang termasuk osteoartritis lutut yaitu 13.3%. Prevalensi indeks massa tubuh berlebih di Indonesia pada tahun 2018  meningkat dari 26.3% menjadi 34.4% sehingga kemungkinan terjadinya osteoartritis lutut juga meningkat. Penelitian ini menggunakan metode observasional analitik dengan desain cross-sectional dilakukan dengan cara mengukur berat badan dan tinggi badan responden yang memenuhi kriteria penelitian berdasarkan pedoman American College of Rheumatology (ACR). Sampel dikumpulkan berdasarkan rekam medis di Rumah Sakit Umum Zainoel Abidin kota Banda Aceh sejak september hingga oktober 2019 yang melibatkan tujuh puluh responden sebagai sampel penelitian yang dimana 51 responden (72.9%) memiliki indeks massa tubuh berlebih dan 43 responden (61.4%) didiagnosis dengan Osteoartritis lutut. Berdasarkan hasil analisis uji Chi Square, nilai p value yang diperoleh adalah 0.021 (p value ≤ 0,05). Dengan demikian, penelitian ini menunjukkan bahwa terdapat hubungan antara indeks massa tubuh dengan kejadian osteoartritis lutut di Rumah Sakit Umum Zainoel Abidin di kota Banda Aceh.Kata Kunci: Indeks massa tubuh; berat badan lebih, osteoartritis lutut;               Abstract. Body Mass Index (BMI) is a parameter to measure body composition which is classified into underweight, normal and overweight. Overweight has been known to potentially cause knee osteoarthritis. Knee osteoarthritis is a degenerative disease happening on the knee. Based on RISKESDAS 2018, Aceh led Indonesia as a province with the highest number of knee arthritis (13.3%). In the same year, the prevalence of overweight in Indonesia has also increased from 26.3% to 34.4% and is expected to rise annually. This research is an analytic observational using cross sectional design. The method used in this research is body weight and body length measurement of samples fulfilling the criteria based on American College of Rheumatology (ACR). Data were collected based on medicalr record at Zainoel Abidin General Hospital, Banda Aceh, from September to October 2019. We examined 70 respondents, 51 of them (72.9%) had overweight IMT and 43 of them (61.4%) were diagnosed with knee osteoarthritis. Chi Square analysis showed p value 0,021 (p value ≤ 0.05). We concluded that there is a correlation between body mass index with knee osteoarthritis in Zainoel Abidin General Hospital, Banda Aceh.Keyword: Body Mass Index; overweight; knee osteoarthritis;


2012 ◽  
Vol 7 (4) ◽  
pp. 169 ◽  
Author(s):  
Iwan Muhamad Ramdan ◽  
Tiyanpri Bayu Laksmono

Gangguan muskuloskeletal merupakan masalah kesehatan dan keselamatan kerja yang penting karena masih berkontribusi pada penurunan produktivitas kerja. Penelitian ini bertujuan untuk mengetahui hubungan umur tenaga kerja, masa kerja, indeks massa tubuh, dan sikap kerja dengankeluhan gangguan muskuloskeletal pada tenaga kerja wanita di unit produksi bagian kupas di PT SSM Kalimantan Timur. Penelitian kuantitatif yang menggunakan desain penelitian cross sectional ini dilakukan pada tenaga kerja wanita bagian pengupasan yang berjumlah 46 orang (total sampling).Variabel bebas penelitian terdiri dari umur, masa kerja, indeks massa tubuh, dan posisi kerja, sementara variabel terikat adalah keluhan gangguan muskuloskeletal. Analisis data yang digunakan adalah uji chi-square dengan level signifikansi 0,05 (5%). Hasil penelitian menunjukkan tidak terdapat hubungan umur dengan keluhan gangguan muskuloskeletal (p = 0,066),terdapat hubungan yang signifikan antara masa kerja (p = 0,044), indeks massa tubuh (p = 0,025), dan sikap kerja (p = 0,001) dengan keluhan gangguan muskuloskeletal. Perusahaan disarankan untuk membuat kursi kerja yang ergonomis, melakukan rotasi kerja, dan melakukan pelatihan dengan materi tata cara kerja yang ergonomis.Kata kunci: Gangguan muskuloskeletal, produktivitas, sikap kerjaAbstractMusculoskeletal disorders are still a health and safety issue that needs to be examined in more depth, because it still contributes to the decline in labor productivity. The objective of this research was to know the relationship between age, working periode, body mass index and work posture with complaint of musculoskeletal disorders. Quantitative research with crosssectional approach has been done on 46 (total sampling) female labor in peeling sections. The independent variables consisted of age, year, body mass index, and work posture, while the dependent variable was the complaint of musculoskeletal disorders. The data analysis used was chi-square test with a significance level of 0.05 (5%). The results showed no association between age with symptoms of musculoskeletal disorders (p = 0,066), there is a significant association between working period (p = 0,044), bodymass index (p = 0,025), and work posture (p = 0,001) with complaints of musculoskeletal disorders. Companies are advised to make an ergonomic office chair, job rotation, and training with ergonomic material working procedures.Keywords: Musculoskeletal disorders, productivity, work posture


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