scholarly journals PHYTOCHEMICAL STUDY OF THE HERB SANGUISORBA OFFICINALIS L. IN THE REPUBLIC OF BASHKORTO-STAN

2019 ◽  
pp. 279-284
Author(s):  
Alina Ramilevna Kazeeva ◽  
Kira Aleksandrovna Pupykina ◽  
Svetlana Galimullovna Denisova ◽  
Galija Gaitnurovna Shaydullina ◽  
Antonina Anatol'yevna Reut

The main purpose of the work was the phytochemical study of the herb of the blood burnet drug (Sanguisorba officinalis L.) from six regions of the Republic of Bashkortostan and the rationale for the prospect of expanding its use in medicine. The collection of herbs was carried out in the flowering phase. The analysis of raw materials was carried out on the basis of the Bashkir State Medical University. Qualitative and quantitative determination of biologically active substances was carried out according to standard and modified methods. Amino acid composition was determined by x-ray fluorescence method The quantitative characteristics of the following groups of biologically active substances were determined: ascorbic acid (0.307–0.521%), organic (1.46–2.27%) and hydroxycinnamic (1.13–1.30%) acids, carotenoids (31.17–35.89 mg%), polysaccharides (0.43–1.05%), saponins (0.56–0.88%), coumarins (0.285–0.326%), tannins (5.1–6.3%). A characteristic of the amino acid composition. The possibility of using the herb of burnet drug is shown along with the rhizomes and roots, which will solve the problem of waste-free processing of this plant.

2020 ◽  
Vol 100 (4) ◽  
pp. 52-59
Author(s):  
А.S. Kishkentayeva ◽  
◽  
S.N. Mantler ◽  
М.М. Zhakanov ◽  
S.М. Adekenov ◽  
...  

The review summarizes data on biologically active compounds of Achillea nobilis L. and methods of their isolation. From Achillea nobilis L., collected in different places of growth, the following have been isolated: essential oil, the main components of which are monoterpene compounds; sesquiterpene lactones estafiatin, hanphyllin, anobin, chrysartemine A, canin, anolide and tanapartin-β-peroxide; the steroid acetyleucanbin; flavonoids: 3,5-dihydroxy-6,7,8-trimethoxyflavone, 5-hydroxy-3,6,7,4’-tetramethoxyflavone and 5,3’-di-hydroxy-3,6,7,4’-tetramethoxyflavone. It has been determined that the component composition of the essen-tial oil of Achillea nobilis L. largely depends on the soil and climatic factors in the places of its growth, the phase of the growing season and the method of its extraction from plant raw materials, and the extractant used (chloroform, ethanol, hot water, diethyl ether). Antibacterial, antimicrobial, antioxidant, antiparasitic activi-ties are characteristic both for the sums of extractive substances from Achillea nobilis L. and for individual compounds isolated from them. Methods for the isolation of biologically active substances from Achillea nobilis L. for the development of new drug substances are described. The main aim of this work was a com-parative analysis of the available research results on the phytochemical study of Achillea nobilis L.


Author(s):  
V. Yu. Ageyets ◽  
Z. V. Lovkis ◽  
Z. V. Koshak ◽  
A. E. Koshak

The paper raises problems of production of domestic compound feed for valuable fish species. The following representatives of valuable fish species are reared in the Republic of Belarus: rainbow trout, sterlet sturgeon, sturgeon, European and African catfish. All these types need high-quality and inexpensive compound feeds. Production of such feed is developing in our country. All the feeds for valuable fish species are extruded in the modern world. A range of raw materials has been studied that can be used as part of compound feeds for valuable fish species, such as Belarusian made fish meal, dry hemoglobin, soy concentrate, and whey fat concentrate. It has been determined that Belarusian fishmeal is of high quality and not inferior in balance to the amino acid composition of imported fishmeal made in Mauritania, and in terms of leucine and isoleucine level, over 2 times exceeds the imported one. Amino acid composition of dry hemoglobin was studied. It was determined that this feed additive can be used only for balancing feed for crude protein level and practically does not contain such an important essential amino acid as methionine. Valuable fish species are predators, for this reason compound feed contain high amount of protein (up to 50 %) and fat (up to 30 %) depending on the type and age of the fish. Therefore, soy protein concentrate can be used in terms of protein content and absence of anti-nutritional substances in compound feed, and whey-fat concentrate can be used for balancing the formulation for fat content. At the same time, the need for development of such deep processing industry in our republic is noted.


2021 ◽  
pp. 113-119
Author(s):  
Evgeny Evgenievich Kurdyukov ◽  
Elena Fedorovna Semenova ◽  
Ol'ga Aleksandrovna Vodopyanova ◽  
Yakov Petrovich Moiseev ◽  
Olesya Petrovna Rodina ◽  
...  

Dried stevia leaves (Stevia rebaudiana Bertoni) were used as objects of research. We studied the leaves of stevia varieties Ramon sweetener grown in the Penza region, the leaves of stevia varieties Ramon sweetener grown in the Tver region, Krasnodar region, the Republic of Crimea, as well as imported raw stevia from India and Paraguay. The purpose of this work is a comparative study of the amino acid composition of raw stevia grown in different conditions. The amino acid composition of stevia leaves (Stevia rebaudiana Bertoni) was revealed by capillary electrophoresis.13 amino acids were identified, of which eight are "essential" (lysine, phenylalanine, histidine, leucine, isoleucine, methionine, valine, threonine). The proportion of essential amino acids in stevia raw materials ranged from 2.99 to 4.64%. The content of interchangeable acids was: tyrosine from 0.24% to 0.36%, Proline from 0.44 to 0.68%, serine from 0.77 to 1.03%, alanine from 0.48 to 0.83%, glycine from 0.40 to 0.68%. The total amount of amino acids detected is higher in the Ramon sweetener variety grown in the Penza region (9.52%) compared to other samples, the lowest amount is found in stevia grown in Paraguay (6.46%). The results obtained indicate the prospects for further studies of the amino acid composition of Stevia rebaudiana and can characterize this species as a source of valuable medicinal substances with a wide range of pharmacological activity.


Author(s):  
SHAPOVALOVA Nataliia ◽  
VEZHLIVTSEVA Svitlana ◽  
ANTIUSHKO Dmytro

Background. The deficiency of essential nutrients in the human body is the root cause of reduced efficiency, general resistance of the body to various diseases. That is an urgent problem in the context of the spread of coronavirus infection. In this regard, the search for opportunities to meet the needs of the population in food products that contain biologically active substances (BAS) through the use of high-value and at the same time available plant raw materials is extremely important. Marigolds attract special attention among such raw materials. The aim of the work is to study the chemical composition and evaluate the consumer properties of Tagetes L. varieties, zoned in the Kiev region, to prove the possibility of increasing the biological value of pasta by adding to their recipe powder from marigold inflorescences. Materials and methods. The object of research is pasta of B group (noodles). Inflorescences of marigolds of different varieties gathered during the flowering period in July-September 2019–2020 in the territory of Vasylkiv and Obukhiv districts of Kyiv region, Ukraine were used as enriching plant raw materials. The quality of finished pasta was assessed by organoleptic and physicochemical indexes (moisture content and titratable acidity). The content of mineral elements in the fine powder of marigold inflorescences was determined on the EXHERT-3L device, the quantitative composition and BAS identification – by spectrophotometric analysis on the device Specord-200 Analytic Jena UV-vis. The integrated quality index of pasta products was calculated taking into account the importance factors of individual indexes. Results. Comparing the obtained results, we can state that all the studied varieties – Gold Kopfen, Orange Flame, Hawaii, Equinox are characterized by high biological value, regardless of the area of collection. As a result of calculated and experimental studies it was determined that the addition of 7 % of the supplement does not provide the required supply of vitamins and minerals. Replacing the flour in the recipe by 20 % significantly improves the mineral composition, but deteriorates the taste and aromatic properties of pasta. The most optimal and rational amount of added additive is 15 %, as it improves the organoleptic properties of pasta and enriches their BAS. Conclusion. The usage of non-traditional vegetable raw materials, in particular powder from marigold inflorescences, which is rich in biologically active substances, allows not only to expand the range, improve the quality of finished products, but also increase the biological value of the product. The optimal amount of additive –powder from marigold inflorescences, was defined. It is 15 % by weight of flour in the production of noodles. This concentration allows not only to improve the organoleptic properties, but also to increase the content of biologically active substances – vitamins, micro- and macronutrients. The usage of non-traditional natural raw materials (powder from marigold inflorescences) allows to abandon artificial colorsand give the finished pasta a pleasant colorand aroma.


2018 ◽  
pp. 30-36
Author(s):  
V. M. Minarchenko ◽  
A. Yu. Butko

The popularity of herbal remedies and medicines, with the participation of biologically active substances from plants is traditionally high. The annual increase of the domestic market for herbal remedies is due to the preservation and modernization of production capacities for processing of medicinal vegetative raw materials in Ukraine, introduction of modern scientific developments, a large natural resource base of medicinal plants and attracting investments in the development of this industry. The aim of our work was the study of the domestic market of medicines of plant origin, which includes herbal remedies, substances and preparations with the participation of biologically active substances from plants. The object of the study was domestic medicines of plant origin that are registered in Ukraine for 2012–2017. The study used the analytical, statistical methods, and the results of its own resource studies of medicinal plants. Phytopharmaceutical market of Ukraine is actively developing due to the attraction of new types of medicinal plants and expanding the range of medicines. The number of domestic drugs with the participation of biologically active substances from plants has increased by 17.4% compared with 2014. It is established that as of 1 January 2017 in Ukraine was 1 141 the form of medicinal drugs of plant origin. Of them: 645 – domestic products, 496 – foreign. Most of the herbal drugs in the pharmaceutical market of Ukraine are made from wild and cultivated domestic raw materials.


Vestnik MGTU ◽  
2020 ◽  
Vol 23 (3) ◽  
pp. 205-213
Author(s):  
N. V. Linovskaya ◽  
E. V. Mazukabzova ◽  
O. S. Rudenko ◽  
T. V. Savenkova

Milk chocolate is particularly popular with different age groups. It is characterized by low protein content with a large amount of fats and carbohydrates determining the food imbalance of the product. In conditions of high-grade animal proteins deficiency the selection of high-quality protein-containing ingredients for food production is very relevant. The aim of this work is to study the protein adequacy of various components of milk chocolate to enhance its biological value. The amino acid scale method has been used to assess the biological value of proteins; it is based on the determination of amino acid (chemical) score. It has been found that the limiting biological value amino acid for classical white raw ingredients of milk chocolate (cocoa products and milk powder) is methionine + cysteine. For constructing chocolate formulas with increased biological value it is advisable to use protein-containing raw materials (whey protein concentrate, oat flour, etc.) to compensate for the limiting amino acids. The indicator of amino acids utilitarianity of proteins of raw milk chocolate components has been calculated. On the basis of the utilitarian index we have established the coefficient of utilitarian of the amino acid composition of the raw materials characterizing essential amino acids' balance. We have determined the biological value of protein and the amino acid composition imbalance coefficient. It has been found that the amino acid composition of milk and whey protein concentrates is most balanced compared to the amino acid composition of traditional protein-containing raw components of milk chocolate. The limiting acid of whey protein concentrate is valine, which makes its use in the manufacture of chocolate products more attractive compared to milk protein concentrate (the limiting amino acid is methionine + cysteine). In the group of vegetable non-conventional raw materials oat and buckwheat flour are characterized by the best indicators of biological value. The amino acid adequacy of oat flour is comparable to the qualitative protein indicators of cocoa products, the limiting amino acid is lysine. Buckwheat flour is characterized by the smallest imbalance in amino acid composition, which distinguishes the proteins of this raw material with the highest degree of digestibility compared with the proteins of all the studied protein-containing components of milk chocolate.


Author(s):  
G.А. Zhorov ◽  
◽  
L.L. Zakharova ◽  
V.N. Obryvin ◽  
◽  
...  

For correctly assess the effectiveness and safety of the use of sorption-detoxifying agents and feed additives intended for animals receiving feed with an excess content of toxicants, it is necessary to take into account the background levels of radionuclides, toxic elements, pesticides and other technogenic and natural pollutants in the studied substances. The need for such studies is due both to the existence of areas with a naturally elevated level of natural toxicants in the sources of raw materials for the production of additives and drugs, and to the increasing anthropogenic influence, accompanied by the entry of xenobiotics into environmental objects. In series of radiometric studies, the specific activity of technogenic and natural radioactive isotopes (90Sr, 137Cs, 40К, 226Ra, 232Th) in a number of sorption-detoxifying and biologically active substances and preparations used in animal husbandry and veterinary medicine as part of feed additives and pharmacological agents was determined. It was found that in 43% of the studied samples, the level of specific activity of 1,1Sr in 3-90 times higher than allowed by the current standards. The maximum level of 90Sr, equal to (137±9) Bq/kg, was detected in perlite. The specific activity of 137Cs did not exceed the permissible level: in mineral sorbents its amount reached (40±7) Bq/kg, in organic and complex sorbents – (24±4), and in feed additives – (29±8) Bq/kg. The maximum levels of 40K were (1429±83) Bq/ kg in minerals (radionite) and (2613±100) Bq/kg in organic substances (lignohumate). The levels of 226Ra and 232Th did not exceed (153±13) and (79±13) Bq/kg, respectively, and were higher in the mineral samples.


2019 ◽  
pp. 205-216
Author(s):  
Vladimir Il'ich Otmahov ◽  
Inessa Vladimirovna Shilova ◽  
Elena Vasil'yevna Petrova ◽  
Anastasiya Alekseyevna Loginova ◽  
Evgeniya Sergeyevna Rabtsevich ◽  
...  

Using the methods of arc atomic emission spectrometry (AAES), atomic emission flame photometry (AEFP), atomic absorption spectrometry (AAS) and mass spectrometry (ICP-MS), the elemental composition of the aerial part of widely used in medical practice Alfredia cernua and Filipendula ulmaria, extracts and fractions obtained from them, is investigated. It was shown that not only biologically active substances, but also mineral elements are extracted by extractants, which may be due both to the formation of complexes with biologically active substances and affinity for extractants. Therefore, the elemental composition must be considered as an important component of plant extracts and medicinal products obtained from them. Simultaneously with biologically active substances in ethanol extracts there is an accumulation of not only biogenic, but also toxic elements, which degree of extraction is often higher. It increases even more during the transition from periodic to countercurrent extraction, which allows to obtain extracts with the highest yield of biologically active substances. Since the enriched extract is directly used to obtain the dosage form, a preliminary elemental analysis is necessary. Analytical control of the content of TM is also necessary when choosing the place of growth of plants raw materials, which are used to create medicinal herbal remedies.


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