scholarly journals Effectiveness of medicinal herbs on psychological indices before and after surgeries

2019 ◽  
Vol 6 (3) ◽  
pp. 321-327
Author(s):  
Gholamreza Shabanian ◽  
Saeid Heidari-Soureshjani ◽  
Johannes Salcher

Psychological complications appear to be significant disorders which need prolonged recovery period. They cause disability and impose hospitalized costs on patients. This systematic review was aimed to investigate the effectiveness of medicinal herbs on psychological indices in patients undergoing surgeries. The keywords such as anxiety, depression, aggressive, impulsive, stress, delirium and cognitive in combination with surgery and medicinal plants search terms such as medicinal plant or phyto or herb were used to search for relevant publications indexed in the Institute for Scientific Information (ISI), Scopus and PubMed using EndNote software. A total of 1231 studies with mentioned keywords were added to the bank of the study and after considering inclusion and exclusion criteria, 36 human studies were reviewed. Some medicinal plants such as Passiflora incarnata L., Valeriana officinalis L., Melissa officinalis L., Crocus sativus L., and Rosa damascena Mill. and some herbal formulas like Hochu-ekki-to and Yokukansan and also some phytochemicals such as ?-6 PUFA and Gastrodin reduce the psychological symptoms in several ways in the patients undergoing operation. Most of the clinical studies were carried out on aromatherapy and the others were based on oral administration. Taken together, using medicinal herbs in medical settings before and after surgery is an effective alternative way for alleviating some psychological disorders such as anxiety, depression, aggressive and impulsive behavior, stress, delirium and cognitive dysfunction. However, the surgeons and anesthesiologists must be aware of their interaction and possible complications.

Author(s):  
Hajar ZIAEI HEZARJARIBI ◽  
Najmeh NADEALI ◽  
Mahdi FAKHAR ◽  
Masoud SOOSARAEI

Background: Trichomoniasis, due to Trichomonas vaginalis, is one of the most common sexually transmitted parasitic diseases in the world such as Iran. This systematic review aimed to explore the studies evaluating the medicinal herbs with anti- T. vaginalis activity which used in Iran. Methods: Articles published in 4 Persian and 4 English databases were obtained between 2000 and 2015 including Google Scholar, PubMed, Science Direct, Scopus, Magiran, Barakatkns (formerly IranMedex), Elm net, and SID (Scientific Information Database). Studies out of Iran, studies on animal models and articles on other parasite species than T. vaginalis were excluded from this review. Results: Twenty-one articles including in vitro experiments, met our eligibility criteria. Thoroughly, 26 types of plants were examined against T. vaginalis. Medicinal herbs such as Artemisia, Zataria multiflora, and Lavandula angustifolia are remarkably effective on T. vaginalis. As such, use of other parts of these plants in different concentrations and timelines is recommended for future in vivo studies. Conclusion: The present systematic review provides comprehensive and useful information about Iranian medicinal plants with anti-T. vaginalis activity, which would be examined in the future experimental and clinical trials and herbal combination therapy.


Author(s):  
Farzaneh Shakeri ◽  
Vahideh Ghorani ◽  
Saeideh Saadat ◽  
Zahra Gholamnezhad ◽  
Mohammad Hossein Boskabady

Medicinal plants have been identified and used as primary sources in prevention and treatment of pulmonary diseases (mainly obstructive pulmonary diseases) from ancient times due to various pharmacological activities. In this review, the stimulatory effects of extracts, some fractions and constituents of medicinal plants on β2-adrenoceptors which could be used as possible therapeutic agents in the future were reviewed. Various databases including; Medline, PubMed, ScienceDirect, Scopus, and Google Scholar were searched using stimulatory effect, β2-adrenoceptors, possible mechanism, tracheal smooth muscle (TSM), medicinal plants and their constituents as keywords from 1985 to 2017. All studied plants including; Nigella sativa, Rosa damascena, Thymus vulgaris, Carum copticom, Carum carvi, Zataria multiflora, Crocus sativus, Cuminum cyminum, Liomnia acidissima, Portulaca oleraceae, Satureja hortensis, Ephedra sinica and Achillea millefolium showed relaxant effect on tracheal smooth muscle with a stimulatory effect on β2-adrenoceptors mechanism. The studied plants and their constituents could be of therapeutic value in clinical practice as a bronchodilatory drug by β2-adrenoceptors stimulatory mechanism for treatment of obstructive pulmonary diseases.


Author(s):  
Mohammad Mahdi Ahmadian-Attari ◽  
Seyed Hamed Moosavi-Asil ◽  
Leila Mohammad Taghizadeh Kashani ◽  
Meysam Shirzad

Premature ejaculation (PE) is one of the main sexual problems among the male population. There is a folk treatment for this ailment in a small town near Kashan, Iran. The treatment contains hydro-alcoholic extracts of Tribulus terrestris L., Rosa × damascena Herrm, Zingiber officinale Roscoe, and Crocus sativus L. in honey. The aim of this preliminary study was to evaluate the effect of the syrup on premature ejaculation. The study population was 17 outpatients visited by a traditional healer. Each patient was diagnosed clinically based on the Premature Ejaculation Diagnostic Tool (PEDT). Inclusion criteria included male participants between 20 to 60 years old, PE more than 6 months, PEDT score more than 11, IELT more than 1 minute, no severe organic disease. Exclusion criteria included taking any chemical drug during the intervention, and sexual contacts less than twice in 3 weeks. 17 male patients aged between 26-65 years old were eligible for the study according to the inclusion criteria. The patients enrolled in the study, filled out the written consent form and conditions of the research were explained. The medication (Bastibaj syrup) was administered for the patients 5 milliliters 3 times daily for 3 sequential weeks. The intravaginal ejaculatory latency time was recorded in all coitus. After the course of the intervention, the mean of IELTs before and after the intervention was compared via paired T-test. Results show that the mean IELT before the intervention (33.2 seconds) in comparison to after it (129.3 seconds) has been improved significantly (P < 0.01). According to the results, the study revealed that the traditional remedy prescribed in this study, i.e. Bastibaj, can be effective in patients with premature ejaculation, and can prolong the IELT significantly.


2019 ◽  
Vol 6 (4) ◽  
pp. 383-388
Author(s):  
Saber Abbaszadeh ◽  
Parisa Arvin ◽  
Mojtaba Khaksarian

Chronic pain can be periodic, persistent, or even a combination of both. Unlike acute pain, chronic pain is not usually useful, reduces the quality of life and functional abilities and also weakens mental health, interpersonal relationships, and financial status, leading to changes in appetite, sleep disorders, psychomotor retardation, tiredness and depression. Human being has always faced various kinds of pain during life and sought to relieve his pain. Pain is a sign of a disease that acts as a warning mechanism and informs of a tissue injury. In this regard, the analgesic effects of many medicinal plants have also been studied. Therefore, in this review study, indigenous medicinal plants with anti-chronic pain effects were reported. Information to conduct this review was obtained using the keywords chronic pain, herbal drug, Iran, medicinal plants, extracts and essential oils to retrieve articles indexed in databases such as Scopus, SID, Magiran, Google Scholar and other Persian databases. The related articles were reviewed for plants serving as chronic pain killers. After reviewing the literature, it was found that Solanum melongena, Hyoscyamus niger, Phoenix dactylifera, Cinnamomum zeylanicum, Artemisia sieberi, Crocus sativus, Carum copticum, Euphorbia helioscopia, Hypericum perforatum, Cucurbita maxima, Passiflora caerulea, Rosa damascena, Tanacetum parthenium, Allium jesdianum and Pistacia atlantica among indigenous medicinal plants with analgesic effect.


Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1237
Author(s):  
Nikolaos Pitsikas

Schizophrenia is a chronic mental devastating disease. Current therapy suffers from various limitations including low efficacy and serious side effects. Thus, there is an urgent necessity to develop new antipsychotics with higher efficacy and safety. The dried stigma of the plant Crocus sativus L., (CS) commonly known as saffron, are used in traditional medicine for various purposes. It has been demonstrated that saffron and its bioactive components crocins and safranal exert a beneficial action in different pathologies of the central nervous system such as anxiety, depression, epilepsy and memory problems. Recently, their role as potential antipsychotic agents is under investigation. In the present review, I intended to critically assess advances in research of these molecules for the treatment of schizophrenia, comment on their advantages over currently used neuroleptics as well-remaining challenges. Up to our days, few preclinical studies have been conducted to this end. In spite of it, results are encouraging and strongly corroborate that additional research is mandatory aiming to definitively establish a role for saffron and its bioactive components for the treatment of schizophrenia.


1985 ◽  
Vol 69 (5) ◽  
pp. 505-510 ◽  
Author(s):  
E. Hultman ◽  
S. Del Canale ◽  
H. Sjöholm

1. Five volunteers were studied before and after oral administration of NH4Cl (0.3 g/kg body wt.) given in order to create a moderate acidosis. 2. The quadriceps femoris muscles were stimulated electrically for 75 s and muscle biopsies for determination of pH and metabolite content were taken before, at the end of contraction and after 10 min in the recovery period. 3. Muscle pH at rest (mean 7.04) was not significantly decreased after acidification despite an extracellular pH decrease of 0.15 unit. 4. After contraction muscle pH was significantly lower after NH4Cl. Mean values before and after acidification were 6.70 and 6.54 respectively. 5. The buffer capacity calculated as the total capacity of the muscle to buffer H+ produced during the isometric contraction before and after NH4Cl ingestion was reduced from 68.6 sl to 54.5 sl. 6. The force produced by contracting muscle was significantly lower at the end of the contraction period after NH4Cl ingestion, 44.6% of initial compared with 55.4% without NH4Cl.


2021 ◽  
Vol 25 ◽  
Author(s):  
Mohamad Hesam Shahrajabian

: One of the principal causes of different disorders is an uncontrolled inflammatory response. Alkaloids, flavonoids, polyphenolic, proanthocyanidin, terpenoid, and steroid compounds are the main reasons for the anti-inflammatory activities of medicinal herbs and plants. The current manuscript introduces a series of potential anti-inflammatory plants, particularly those which are routines in Iranian and Chinese traditional herbal medicine, and simplifies the function and mechanisms of natural constituents for the prevention and treatment of inflammatory disorders. PubMed, Science Direct, Google Scholar, Wiley Online Library, Springer, Taylor, Francis, etc., have been used to search for collecting of scientific publications for a full evaluation of current documentation in the literature showing the importance of medicinal plants with anti-inflammatory characteristics and natural medicines. The most notable medicinal plants with anti-inflammatory activities are Baccharis dracunculifolia, Aconitum bulleyanum, Crateya adansonii, Alliums spp., Centella asiatica, Flos lonicerae, Corydalis dubia, Syringae folium, Coptis chinensis, Casearia decandra, Nigella sativa, Cannabis sativa, Tamarindus indica L., Glycyrrhiza glabra, Panax ginseng, Panax notoginseng, Pistacia vera, Smilax china, Scutellaria baicalensis, Rosemarinus officinalis, Moringa olifera, Pulsatilla radix, Pistacia atlantica, Rullia tuberose, Canarium album, Dodonaea polyandra, Forsythia suspense, Polygala tenuifolia, Radiz Isatidis, Hypericum sampsonii, Geranium koreanum, Typha capensis, Isatidis folium, Ginkgo biloba, Houttuynia cordata, snow lotus, etc. Herbal medicine mainly uses numerous parts of plants or combinations of them to prevent and remedy diseases and promote health. More investigations and clinical experiments are needed to provide more information on the importance of medicinal plants as well as their roles in the treatment and prevention of inflammatory diseases.


Author(s):  
Dinesh Kumar Patel

Background: Herbal drugs and their derived phytochemicals are valuable for human being as a source of vital component of food material and drugs. Flavonoids are naturally occurring phytochemical produced in plants through metabolisms and they are having anti-hyperlipidemia, anti-inflammatory, anti-oxidant and anti-apoptotic activity. Flavonoids have been identified in the fruits, nuts, vegetables, seeds, stem, flowers and tea. Kaempferol is a natural flavonoidal compound present in edible plants such as apples, broccoli, strawberries, beans, grapefruit, propolis and medicinal plants such as Aloe vera, Ginkgo biloba, Rosmarinus officinalis, Crocus sativus L., Hypericum perforatum L. Kaempferol have anti-oxidant, anti-inflammatory, anti-apoptotic, pro-apoptotic, cardio-protective and anti-cancer activities. Methods: Glycosides of kaempferol such as kaempferitrin also called kaempferol 3,7-dirhamnoside are known to be more abundant than their flavonoid monomers in plants. Various literature databases have been searched to collect all the scientific information of kaempferitrin in the present investigation and analyzed in order to know the therapeutic benefit and biological potential of kaempferitrin. Moreover all the information has been presented here in two broad sections i.e. pharmacological and analytical. Results: From the analysis of all the collected and presented information, it was found that kaempferitrin has potent insulin-mimetic potential and could be used for the treatment of diabetes and related complication. However, it has also shown anti-oxidant, anti-inflammatory, anti-convulsant, anti-osteoporotic, anti-depressant, anthelmintic, immunostimulatory and natriuretic properties and inhibits cell proliferation and apoptosis. Kaempferitrin also improves meat quality of broiler chickens. Conclusions: The presented information in this work will be valuable to justify the biological importance and therapeutic potential of kaempferitrin in the scientific field.


2018 ◽  
Vol 23 (5) ◽  
pp. 298-308 ◽  
Author(s):  
Dominique Vibert ◽  
John H.J. Allum ◽  
Martin Kompis ◽  
Simona Wiedmer ◽  
Christof Stieger ◽  
...  

The aim of this study was to investigate changes in balance control for stance and gait tasks in patients 2 years before and after vestibular neurectomy (VN) performed to alleviate intractable Meniere’s disease. Amplitudes of trunk sway in roll and pitch directions were measured for stance and gait tasks in 19 patients using gyroscopes mounted at the lower-back. Measurements before VN and 2 years later were compared to those of healthy age-matched controls (HC). We also examined if changes in trunk sway amplitudes were correlated with patients’ subjective assessment of disability using the AAO-HNS scale. For patients with low AAO-HNS scores 0–2 (n = 14), trunk roll and pitch sway velocities, standing eyes closed on foam, increased 2 years post VN compared to HC values (p < 0.01). Trunk sway amplitudes remained at levels of HC for simple gait tasks, but task durations were longer and therefore gait slower. For complex gait tasks (stairs), balance control remained impaired at 2 years. In patients with AAO-HNS high scores level 6 (n = 5), balance control remained abnormal, compared to HC, 2 years postoperatively for all stance, several simple and all complex gait tasks. Trunk sway in the pitch and roll directions for stance tasks was correlated with clinical (AAO-HNS) scores (p ≤ 0.05). These results indicate that VN leads to chronic balance problems for stance and complex gait tasks. The problems are greater for patients with high compared to low AAO-HNS scores, thereby explaining the different symptoms reported by these patients. The lack of balance recovery in VN patients to levels of HCs after 2 years contrasts with the 3 months average recovery period for acute vestibular neuritis patients and is indicative of the effects of neurectomy on central compensation processes.


1993 ◽  
Vol 75 (1) ◽  
pp. 173-180 ◽  
Author(s):  
M. J. McKenna ◽  
T. A. Schmidt ◽  
M. Hargreaves ◽  
L. Cameron ◽  
S. L. Skinner ◽  
...  

This study investigated the effects of sprint training on muscle Na(+)-K(+)-adenosinetriphosphatase (ATPase) concentration, plasma [K+] regulation, muscle performance, and fatigue during severe intermittent exercise. Six untrained male subjects underwent intensive cycle-sprint training for 7 wk. Muscle biopsies were taken at rest from the vastus lateralis muscle before and after 7 wk of training and were assayed for Na(+)-K(+)-ATPase concentration using vanadate-facilitated [3H]ouabain binding to intact samples. Before and after the training period, subjects performed four maximal 30-s exercise bouts (EB) on a cycle ergometer, each separated by a 4-min recovery. Arterialized venous blood samples were drawn immediately before and after each sprint bout and were analyzed for plasma [K+]. The work output was significantly elevated (11%) across all four EBs after training. The muscle [3H]ouabain binding site concentration was significantly increased (16%) from 333 +/- 19 to 387 +/- 15 (SE) pmol/g wet wt after training but was unchanged in muscle obtained from three control subjects. Plasma [K+] rose by 1–2 mmol/l with each EB and declined rapidly by the end of each recovery period. The increases in plasma [K+] resulting from each EB were significantly lower (19%) after training. The ratios of rise in plasma [K+] relative to work output during each EB were also significantly lower (27%) after training. The increased muscle [3H]ouabain binding site concentration and the reduced ratio of rise in [K+] relative to work output with exercise are both consistent with improved plasma and skeletal muscle K+ regulation after sprint training.


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