scholarly journals Variation in the Ace Gene in Elite Polish Football Players

2016 ◽  
Vol 17 (4) ◽  
Author(s):  
Paweł Cięszczyk ◽  
Agata Leońska-Duniec ◽  
Agnieszka Maciejewska-Skrendo ◽  
Marek Sawczuk ◽  
Katarzyna Leźnicka ◽  
...  

AbstractPurpose. A common polymorphism in the angiotensin converting enzyme I gene (the ACE I/D variant) represents one of the first characterized and the most widely studied genetic variants in the context of elite athletes status and performance related traits. The aim of the study was to determine the genotype and allele distribution of the allele and genotype of the ACE gene in Polish male football players. Methods. The total of 106 Polish male professional football players were recruited. They were divided into groups according to the position in the field: forwards, defenders, midfielders, and goalkeepers. For controls, samples were prepared with 115 unrelated volunteers. DNA was extracted from the buccal cells donated by the subjects, and the PCR amplification of the polymorphic region of the ACE gene containing either the insertion (I) or deletion (D) fragment was performed. Results. The genotype distribution and allele frequencies among all football players did not differ significantly when compared with sedentary control individuals (p = 0.887, p = 0.999, respectively). Likewise, the analysis of forwards, defenders, midfielders, and goalkeepers revealed no significant differences in either ACE genotype or allele frequencies. Conclusions. We did not provide evidence for difference of variation of the ACE I/D polymorphism between Polish football players and controls, as we did not obtain any statistically significantly higher frequency of either of the analysed alleles (I and D) or genotypes (DD, ID, and II) in the studied subgroups. It may be suspected that harbouring of I/D allelic variants of the ACE gene neither decreases nor increases the probability of being a professional football player in Poland.

Author(s):  
P. Gomez-Piqueras ◽  
S. Gonzalez-Villora ◽  
M. Sanchez-Gonzalez ◽  
P. Sainz de Baranda

Objetivo – El objetivo del presente estudio consistió en establecer valores de referencia para futbolistas profesionales en una serie de test funcionales seleccionados previamente. Método – Durante dos temporadas (2012/13 y 2013/14) y en tres momentos distintos de las mismas, 42 futbolistas profesionales fueron evaluados funcionalmente mediante las siguientes pruebas: CMJ (salto bipodal), 5 m Shuttle Run Sprint Test (velocidad/agilidad), Test de Barrow (agilidad), Y Balance Test (control postural), Single Hop Test y Triple Hop Test (salto unipodal). Resultados – Los valores medios obtenidos fueron: CMJ (40.25±4.13cm), 5 m Shuttle Run Sprint Test (10.89±0.38 segundos), Test de Barrow (7.46±0.27 segundos), Y Balance asimetría derecha (4.63±2.16%), Y Balance asimetría izquierda (3.91±2.25%), Single Hop Test derecha (2.06±0.11 metros), Single Hop Test izquierda (2.07±0.12 metros), Triple Hop Test derecha (6.87±0.29 metros) y Triple Hop Test izquierda (6.83±0.31). Conclusión – Este trabajo contribuye aportando valores de referencia que puedan ser utilizados para cuantificar el grado de recuperación funcional durante la recuperación de un futbolista profesional lesionado. Aim - The objective of this study was to establish reference values for professional football players in a series of previously selected functional tests. Methods - 42 professional football players were functionally assessed during two seasons (2012/13 and 2013/14), at three different times: preseason, midpoint of the season and end of the season. For this purpose, the following tests were carried out: Counter Movement Jump (bipodal jump), 5 metres Shuttle Run Sprint Test (speed/agility), Barrow Test (agility), Y Balance Test (posture control), Single Hop Test and Triple Hop Test (unipodal jump). Results - The average obtained values were: Counter Movement Jump (40.25±4.13cm), 5 metres Shuttle Run Sprint Test (10.89±0.38 seconds), Barrow Test (7.46±0.27 seconds), right asymmetry Y Balance Test (4.63±2.16%), left asymmetry Y Balance Test (3.91±2.25%), right Single Hop Test (2.06±0.11 meters), left Single Hop Test (2.07±0.12 meters), right Triple Hop Test (6.87±0.29 meters) and left Triple Hop Test (6.83±0.31). Conclusion - This paper contributes reference values which can be used to determine the sports performance or quantify the degree of functional recovery of an professional injured football player during his recovery.


2015 ◽  
Vol 47 (1) ◽  
pp. 99-106 ◽  
Author(s):  
Agata Grenda ◽  
Marek Sawczuk ◽  
Mariusz Kaczmarczyk ◽  
Agnieszka Maciejewska ◽  
Danuta Umiastowska ◽  
...  

Abstract Single nucleotide polymorphism C825T located within the GNB3 gene has been proposed in the literature as the performance enhancing polymorphism in highly trained athletes. Therefore, the aim of the present study was to verify the hypothesis assuming an association between the C825T polymorphic site and performance of competitive swimmers. The frequencies of C/T alleles and distribution of CC, CT and TT genotypes of the C825T GNB3 polymorphism were compared between athletes and nonathletic controls as well as between sprint and endurance swimmers. Genomic DNA was extracted from 197 competitive swimmers (50 long distance swimmers (LDS) and 147 short distance swimmers (SDS)) and 379 sedentary volunteers. The allele frequencies and genotype distribution of the C825T polymorphic site were not significantly different when LDS and SDS were compared to sedentary controls. Gender-specific analysis did not reveal any significant differences in allele and genotype distribution, neither between female controls and female swimmers nor between male controls and male swimmers. No significant differences in allele frequencies and genotype distribution were observed when LDS and SDS as well as groups of swimmers stratified by gender were compared. The results of this study do not support the hypothesis that the C825T polymorphism of the GNB3 gene is associated with swimming performance in competitive swimmers.


1999 ◽  
Vol 87 (4) ◽  
pp. 1313-1316 ◽  
Author(s):  
Saul Myerson ◽  
Harry Hemingway ◽  
Richard Budget ◽  
John Martin ◽  
Steve Humphries ◽  
...  

Human physical performance is strongly influenced by genetic factors. A variation in the structure of the human angiotensin I-converting enzyme (ACE) gene has been reported in which the insertion (I) variant is associated with lower ACE levels than the deletion (D) gene. We have previously reported that the I variant was associated with improved endurance performance in high-altitude mountaineers and British Army recruits. We now examine this genotype distribution in 91 British Olympic-standard runners (79 Caucasians). DNA was extracted from the buccal cells contained in 10 ml of saline mouthwash donated by the subjects, and the I and D variants of the ACE gene were identified by PCR amplification of the polymorphic region. There was an increasing frequency of the I allele with distance run [0.35, 0.53, and 0.62 for ≤200 m ( n = 20), 400–3,000 m ( n = 37), and ≥5,000 m ( n = 34), respectively; P = 0.009 for linear trend]. Among 404 Olympic-standard athletes from 19 other mixed sporting disciplines (in which endurance performance was not necessarily a key factor), the I allele did not differ significantly from that found in control subjects: 0.50 vs. 0.49 ( P = 0.526). These results support a positive association of the I allele with elite endurance performance.


2018 ◽  
Vol 39 (13) ◽  
pp. 1028-1034 ◽  
Author(s):  
Paweł Cięszczyk ◽  
Carla Maria Calò ◽  
Myosotis Massidda ◽  
Alberto Mendez-Villanueva ◽  
Valentina Ginevičienė ◽  
...  

AbstractThe aim of this study was to investigate the association between the MCT1 (monocarboxylate transporter 1) A1470T polymorphism and positional roles in a large cohort of professional football players from five different countries. We compared genotype distributions of the MCT1 A1470T polymorphism between football players (n=694) and non-athlete controls (n=781) from Italy, Poland, Lithuania, Ukraine and Malta, and we analyzed the MCT1 genotype distributions with respect to the players’ positions in the field (e. g. forwards, midfielders, defenders and goalkeepers). Genomic DNA was extracted from either buccal epithelium or peripheral blood using a standard protocol. In the pooled cohort of Italian, Polish, Lithuanian and Ukrainian football players, forwards (n=148) were more likely than controls (n=781) to possess the A allele (χ2=7.067, p=0.029, FDR q value 0.116), with a greater likelihood of having the AA genotype compared with the TT genotype (OR=1.97; C.I.=1.07-3.64; p=0.021, FDR q value 0.086). The MCT1 AA genotype was significantly more frequent in forwards then in controls. Further studies are needed to confirm these findings in other professional football player cohorts.


2019 ◽  
Vol 4 (1) ◽  
pp. 42
Author(s):  
Amin Akbar ◽  
Thomas Dicky Hastjarjo

This study aims to determine the role of team cohesiveness and attitude toward referee leadership to the aggressiveness tendency in Indonesian professional football player. Participants in this research were 90 Indonesian professional football players in "Liga Satu Gojek-Traveloka". The data were collected using three instruments: aggressiveness behavioral tendencies scale, team cohesiveness scale, and attitude toward referee leadership scale. Data were analyzed using linear regression analysis in SPSS 20. Findings from this research were the team cohesiveness and the attitude towards referee leadership have contributed in aggressive behavioral tendencies of Indonesian professional football player, shown by the value of R = 0.509 and R square = 0.259 p <0.01. Team cohesiveness and the attitude toward referee leadership effectively contribute as much as 25.9% on the aggressiveness tendency among Indonesia professional football players.


2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Ara Kassarjian ◽  
Eleanor Elstein

This study investigated the frequency of ACE genotypes in sporadic hypertrophic cardiomyopathy (HCM) and compared these frequencies to those found in the general population and in familial HCM. Delineation of the genotype of a 287 bp fragment in the ACE gene of 10 patients with confirmed sporadic HCM demonstrated that 2 (20%) were of the DD genotype, 5 (50%) of the ID genotype, and 3 (30%) of the II genotype. These genotype distributions did not differ significantly from controls (p < 0.57). Comparison of the present results with genotype frequencies in familial HCM reported in prior studies revealed a significant difference in genotype distribution between sporadic and familial HCM (p < 0.04). These findings indicate that the frequency of the ACE genotype does not appear to differ between patients with sporadic HCM and the general population. However, the results suggest that, with regard to the ACE polymorphism studied, genetic differences may exist between the sporadic and familial forms of HCM.


Author(s):  
Rasool Nazari ◽  
Saeid Mahmoodizad Azari

The present study intends to design a value model for professional players in the Iranian Football. The present study has been done with exploratory nature and with the aim of expanding the existing knowledge and understanding about capabilities in the field of football in order to present the model from the findings derived from the code, an attempt has been made to use a structural approach of data-based theory of the Charms Foundation. Three overlapping processes in the structural analysis of data-based theory are: Primary, centralized, and theoretical coding. In the implementation of the research, data collection and analysis were done consciously simultaneously, and the initial data were collected in order to form the process of continuous data collection. Participants included people familiar with the Iranian professional football, who were purposefully selected. Based on the findings in this stage of the research, out of about 220 sentences implemented from the interviews, after removing duplicate and unrelated items, 109 primary codes were identified and marked by the researcher in the first stage. In centralized coding, it was divided into 7 categories. Finally, at the highest level of reduction or brevity, the categories of construction were reduced to three general categories of equity, requirements and market value of a player, which in the most desirable way, integrated the concepts created in the research into three levels. The final price or value of a football player in the Iranian Premier League in the transfer market is determined based on the player's special values. <p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0795/a.php" alt="Hit counter" /></p>


2021 ◽  
Vol 47 ◽  
pp. 140-146
Author(s):  
César Augusto Bueno ◽  
João Breno de Araujo Ribeiro-Alvares ◽  
Gabriel dos Santos Oliveira ◽  
Rafael Grazioli ◽  
Filipe Veeck ◽  
...  

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