Uninstantiability

Semiotica ◽  
2016 ◽  
Vol 2016 (208) ◽  
pp. 1-20
Author(s):  
John Deely

AbstractJohn Poinsot (1589–1644), aka Joannes a Sancto Thoma, was the first of St Thomas’ followers among the Latins to demonstrate that the origins of animal knowledge in sensation is already – from the first – a matter of the action of signs. This action, “semiosis,” results in the formation of an irreducibly triadic relation apart from which there is no awareness at all on the part of animals. At the level of internal sense, and then again at the level of intellect (the two having in common dependency upon concept-formation in order to interpret the data provided by sensation), Poinsot shows how the concept serves to make objects known only by serving as the foundation for relations which, exactly as those in sensation, exhibit an irreducibly triadic character, with only this difference: that, whereas the triadic relations of sensation are directly founded upon or “provenate from” species impressa (stimulation of sense powers in bodily interaction with the surroundings) determining the external sense powers, the triadic relations of perceptual and intellectual awareness have as their immediate foundations or “sources of provenation” species expressae (“ideas” or concepts) actively formed by the cognitive powers of memory, imagination, estimation, and intellect. Being relations, all of these triadic relations exhibit no direct instantiation as signate matter, and it is this which makes them only indirectly knowable to sense powers. Intellect, by contrast, in being able to know relations precisely in their difference from related objects and things, manifests the species-specific distinctness of human animals in being able to construct and to know and to communicate about objects – beginning with relations – which admit of no direct sensory instantiation. The purpose of this paper is to show how the ability of the human mind to consider objects which admit of no direct instantiation in sense perception is what distinguishes the human being as “semiotic animal” from what the Latins identified as “brute animals,” not because brutes (the “alloanimals,” to use a term from late modern anthropology) are not “rational” in the modern sense of being able creatively to work through problems (indeed they are rational in this sense!), but because human animals are not confined to the consideration of objects as perceptually instantiable.

Phronesis ◽  
2021 ◽  
pp. 1-32
Author(s):  
Eyjólfur K. Emilsson

Abstract This paper discusses the role of innate concepts derived from Intellect in Plotinus’ account of cognition of the sensible realm. Several passages have been claimed as evidence for such innateness, but an analysis of them shows that they do not support this claim. It is tentatively suggested that, nevertheless, some very general concepts such as difference, sameness and being are integral to the faculty of sense and play a crucial role in concept formation. It is further argued that reasoning about the sensible realm takes place to a large extent without the involvement of the higher realms of Plotinus’ hierarchy of being. Clearly, however, for value concepts such as those of goodness, justice and beauty human beings are dependent upon an illumination from Intellect.


Reproduction ◽  
2016 ◽  
Vol 152 (6) ◽  
pp. 727-739 ◽  
Author(s):  
Andrea Miccoli ◽  
Ike Olivotto ◽  
Andrea De Felice ◽  
Iole Leonori ◽  
Oliana Carnevali

The European anchovy Engraulis encrasicolus, a member of the Clupeiformes order, holds a great biological and economical importance. In the past, this species was mostly investigated with the aim of assessing its reproductive biology, trophic ecology, population dynamics and the relations existing with the physical environment. At present days, though, an almost complete lack of information afflicts its neuroendocrinology and reproductive physiology. The hypothalamic–pituitary–gonadal (HPG) axis at its highest levels was herein investigated. In this study, the gonadotropin-releasing hormone (GnRH), a neuropeptide underlying many reproduction-related processes, the most critical of which is the stimulation of gonadotropin synthesis and secretion from the pituitary gland, was cloned. Three forms (salmon GnRH, chicken-II GnRH and the species-specific type) were characterized in their full-length open-reading frames and, in accordance with other Clupeiformes species, the distinctive one was found to be the herring-type GnRH. We qualitatively and semiquantitatively evaluated the localizations of expressions and the temporal transcription patterns of the three GnRH forms in male and female specimens throughout their reproductive cycle as well as described their phylogeny with regard to teleost GnRH lineages, and, specifically, to other Clupeiformes species.


2018 ◽  
Vol 15 (1) ◽  
pp. 103-124
Author(s):  
JONATHAN CROSS

AbstractThe appearance of thecorps sonoreat a key dramatic moment in Rameau'sPygmalion(1748) opens up anespace sensible(a term borrowed from Michel Leiris) where sounds derived from the harmonic series can articulate transformed temporal and spatial environments. Thecorps sonore– rediscovered and repurposed by the spectral movement of the 1970s – reappears in a number of twenty-first-century operas in order to animate a late-modern sense of theespace sensible. Instead of crossing a threshold towards the transcendent, the seemingly immobilecorps sonorecan now represent a modernist sense of loss, death, exile, ruin, and failure. Michaël Levinas's 2010 operatic reinterpretation of Kafka'sMetamorphosisstands as an exemplar of the ways in which the spectrum of sound (here the voice of the ‘becoming-animal’ Gregor Samsa metamorphosed by electronic means) can create a ‘deterritorialized’ space of alienation. Liminal, spectral spaces in works by Dufourt, Grisey, Haas, Harvey, Murail, and Saariaho are also discussed.


Weed Research ◽  
2008 ◽  
Vol 48 (2) ◽  
pp. 163-168 ◽  
Author(s):  
M FERNÁNDEZ-APARICIO ◽  
A ANDOLFI ◽  
A EVIDENTE ◽  
A PÉREZ-DE-LUQUE ◽  
D RUBIALES

1994 ◽  
Vol 72 (4) ◽  
pp. 2015-2025 ◽  
Author(s):  
B. Hedwig

1. In the acridid grasshopper Omocestus viridulus, I performed intracellular recording and stimulation of descending brain neurons simultaneously with the recording of the stridulatory hindleg movements in a minimally dissected preparation. The descending B-DC-3 interneurons were identified with intracellular staining techniques. In each half of the brain at least two sibling B-DC-3 interneurons exist. Main features of the neurons are a medial soma position and a pronounced dendritic arborization within the medial dorsal posterior protocerebrum. The axon descends contralaterally and occupies an extreme medial position in the cervical and thoracic connectives. 2. The occurrence of stridulatory behavior is strictly coupled with tonic spike activity in the B-DC-3 interneurons. During spontaneous stridulation these interneurons discharge action potentials at a rate of approximately 100 action potentials per second. 3. Individual B-DC-3 interneurons are sufficient to initiate and maintain the species-specific leg movements of courtship stridulation. During gradual depolarization stridulation is elicited at discharge rates of approximately 70 action potentials per second. On pulselike depolarization the neurons show a phasic-tonic discharge pattern. 4. The interneurons are necessary for the generation of stridulatory leg movements. Inhibition of an individual B-DC-3 interneuron can stop spontaneous stridulatory motor activity. 5. Depolarization of an individual B-DC-3 interneuron during ongoing spontaneous stridulation increases the repetition rate and amplitude of the stridulatory leg movements. Thus the B-DC-3 interneurons can also modulate the output of the stridulatory pattern generator. 6. Because of their number, structure, and properties, the B-DC-3 interneurons have to be regarded as the command system of stridulation in the acridid grasshopper O. viridulus.


2021 ◽  
Author(s):  
Ryohei Iwata ◽  
Pierre Casimir ◽  
Emir Erkol ◽  
Leila Boubakar ◽  
Melanie Planque ◽  
...  

The evolution of species involves changes in the timeline of key developmental programs. Among these, neuronal development is considerably prolonged in the human cerebral cortex compared with other mammals, leading to brain neoteny. Here we explore whether mitochondria influence the species-specific properties of cortical neuron maturation. By comparing human and mouse cortical neuronal maturation at high temporal and cell resolution, we found a slower pattern of mitochondria development in human cortical neurons compared with the mouse, together with lower mitochondria metabolic activity, particularly oxidative phosphorylation. Stimulation of mitochondria metabolism in human neurons resulted in accelerated maturation, leading to excitable and complex cells weeks ahead of time. Our data identify mitochondria as important regulators of the pace of neuronal development underlying human-specific features of brain evolution.


Author(s):  
Shuang-jin Xu ◽  
Tilat A. Rizvi ◽  
Maorong Jiang ◽  
Matthew Ennis ◽  
Michael T. Shipley

Activation of the midbrain periaqueductal gray (PAG) elicits species specific defense reactions and marked autonomic adjustments. In agreement with recent studies by Bandler and colleagues in the cat, we found that activation of rostrocaudally-oriented, longitudinally organized columns in PAG elicit differential cardiovascular and behavioral responses. Activation of dorsolateral/lateral PAG produces aggressive/flight behaviors accompanied by pressor responses while stimulation of ventrolateral PAG produces immobility and depressor responses. The pathways mediating these selective behavioral and autonomic responses are poorly understood.The projection from PAG to the sympathoexcitatory zone in the rostral ventrolateral medulla is a likely substrate for PAG-evoked pressor responses. However, circuits mediating PAG-evoked depressor responses are not known. The present studies have identified a robust, focal projection from PAG to the nucleus ambiguus (NA), a potent depressor area in the ventral medulla. In addition, we have used tract tracing techniques and immunocytochemistry to examine the organization of PAG projections in relation to cholinergic preganglionic parasympathetic NA neurons that innervate the heart.


Rhizomata ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 247-270
Author(s):  
Lenka Karfíková

Abstract The article treats the role of attention (intentio or attentio) in Augustine’s analysis of sense perception, the notion of time, and the Trinitarian structure of the human mind. The term intentio covers a broad range of meanings in Augustine’s usage. Its most fundamental meaning is the life-giving presence of the soul in the body, intensified in attention’s being concentrated on a particular thing or experience; Augustine also uses the term attentio in this latter sense. According to his analysis of time, by way of attention (intentio or attentio), the soul fixes the present in which the future passes into the past. Due to the intention of the soul, the form abstracted from an external object is both imprinted into the sense organ and retained in the memory in order to be, by intention again, recalled before the sight of mind. As “the intention of the will” or just “the will”, attention connects intellectual understanding with memory. In Augustine’s eyes, attention has a different quality depending on the object it is oriented to, and a different intensity, ranging from inattentive distraction (distentio) to concentrated effort (intentio).


2003 ◽  
Vol 93 (2) ◽  
pp. 160-166 ◽  
Author(s):  
Xinrong Wang ◽  
Nathalie Bosselut ◽  
Chantal Castagnone ◽  
Roger Voisin ◽  
Pierre Abad ◽  
...  

The species X. index, X. diversicaudatum, X. vuittenezi, and X. italiae are established (E) or putative (P) vectors of Grapevine fanleaf virus (GFLV) (E), Arabis mosaic virus (E), Grapevine chrome mosaic virus (P), and GFLV (P) nepoviruses of grapevine, respectively. All four species are very closely related taxonomically and their low field densities make them difficult to identify from morphological and morphometrical diagnostic characters when only single or few individuals are detected. To improve diagnostic accuracy, a simple method was developed. The internal transcribed spacer 1 (ITS1) region spanning the 18S and 5.8S ribosomal genes was sequenced in one population of each species using two conserved primers from these genes. The ITS1 fragments were 1,132 bp (X. vuittenezi), 1,153 bp (X. index), 1,175 bp (X. diversicaudatum), and 1,190 bp (X. italiae), i.e., a difference of over 5% between the extremes. The sequence variability made it possible to design species-specific internal sense primers that amplified, in combination with the same antisense ITS1 primer, a single signature fragment (340 bp for X. index, 414 bp for X. italiae, 591 bp for X. vuittenezi, and 813 bp for X. diversicaudatum). Tests with DNA from a single adult or juvenile nematode confirmed the specificity of the primers from diverse isolates or populations. The primers were successfully used in a multiplex test for the reliable detection of two to four mixed species, each represented by a single individual. This multiplex-based diagnostic tool will be particularly useful for successful nematode management practices in vineyards.


2011 ◽  
Vol 77 (20) ◽  
pp. 7307-7315 ◽  
Author(s):  
Karel Šimek ◽  
Vojtěch Kasalický ◽  
Eliška Zapomělová ◽  
Karel Horňák

ABSTRACTWe examined the proportions of major Betaproteobacteria subgroups within bacterial communities in diverse nonaxenic, monospecific cultures of algae or cyanobacteria: four species of cryptophyta (generaCryptomonasandRhodomonas), four species of chlorophyta (generaPediastrum,Staurastrum, andChlamydomonas), and two species of cyanobacteria (generaDolichospermumandAphanizomenon). In the cryptophyta cultures,Betaproteobacteriarepresented 48 to 71% of total bacteria, the genusLimnohabitansrepresented 18 to 26%, and thePolynucleobacterB subcluster represented 5 to 16%. In the taxonomically diverse chlorophyta group, the genusLimnohabitansaccounted for 7 to 45% of total bacteria. In contrast, cyanobacterial cultures contained significantly lower proportions of theLimnohabitansbacteria (1 to 3% of the total) than the cryptophyta and chlorophyta cultures. Notably, largely absent in all of the cultures wasPolynucleobacter necessarius(PolynucleobacterC subcluster). Subsequently, we examined the growth ofLimnohabitansstrains in the presence of different algae or their extracellular products (EPP). Two strains, affiliated withLimnohabitansplanktonicusandLimnohabitansparvus, were separately inoculated into axenic cultures of three algal species growing in an inorganic medium:Cryptomonassp.,Chlamydomonas noctigama, andPediastrum boryanum. TheLimnohabitansstrains cocultured with these algae or inoculated into their EPP consistently showed (i) pronounced population growth compared to the control without the algae or EPP and (ii) stronger growth stimulation ofL. planktonicusthan ofL. parvus.Overall, growth responses of theLimnohabitansstrains cultured with algae were highly species specific, which suggests a pronounced niche separation between two closely relatedLimnohabitansspecies likely mediated by different abilities to utilize the substrates produced by different algal species.


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