scholarly journals The Role of Emotions in Delusion Formation

2016 ◽  
Vol 48 (1) ◽  
pp. 253-263
Author(s):  
Adrianna Smurzyńska
Keyword(s):  
Emotional Disorders ◽  
Affective Disorders ◽  
Emotional Problems ◽  
Capgras Delusion ◽  
The Core ◽  
Dsm V ◽  
Cognitive Theories ◽  
Dsm Iv

Abstract The text concerns the role of emotions in delusion formation. Provided are definitions from DSM-V and DSM-IV-R and the problems found in those definitions. One of them, the problem of delusion formation, is described when providing cognitive theories of delusions. The core of the paper is a presentation of the emotional and affective disorders in delusions, especially Capgras delusion and Cotard delusion. The author provides a comparison of the kinds of delusions and the conclusions taken from neuroimaging studies. As a result of the fact that an explanation of delusion formation focusing on emotional problems turns out to be insufficient, the author provides examples of the reasoning impairments which coexist with them. At the end of the article, some hypotheses are proposed concerning the role of emotions and reasoning in delusion formation and the relation between belief disorders and emotional disorders.

The (Emotive) worm at the core: The role of emotional problems in the process from physical suffering to psychological distress—A multiple step mediation analysis.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. 10063-10063
Author(s):  
Alessandro Rossi ◽  
Maria Marconi ◽  
Giuseppe Di Lucca ◽  
Raffaella Morena ◽  
Chiara Rossini ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Mediation Analysis ◽  
Emotional Problems ◽  
The Core ◽  
Physical Suffering ◽  
Multiple Step

scholarly journals SYMPTOM PROFILES OF DSM-IV-DEFINED REMISSION, RECOVERY, RELAPSE, AND RECURRENCE OF DEPRESSION: THE ROLE OF THE CORE SYMPTOMS

2012 ◽  
Vol 29 (7) ◽  
pp. 638-645 ◽  
Author(s):  
Henk Jan Conradi ◽  
Johan Ormel ◽  
Peter de Jonge
Keyword(s):  
The Core ◽  
Symptom Profiles ◽  
Dsm Iv ◽  
Core Symptoms

scholarly journals Sleep and Depression: What We Know and What to Learn?

2020 ◽  
pp. 33-49
Author(s):  
Andrey Viktorovich Antsyborov ◽  
Anna Valerievna Kalinchuk ◽  
Irina Vladimirovna Dubatova
Keyword(s):  
Obstructive Sleep Apnea ◽  
Circadian Rhythms ◽  
Affective Disorders ◽  
Sleep Disturbances ◽  
Biological Clock ◽  
The Core ◽  
Obstructive Sleep ◽  
Function Of Sleep ◽  
Depressive Episodes

Presently, a lot of data indicate that the disturbance of mechanisms underlying the regulation of sleep-waking cycle coincides with the mechanisms underlying the development of depression. The disturbance of circadian rhythms is one of the core factors in the genesis of the most affective disorders including depression, which indicates the role of the internal biological clock in the pathophysiology of affective disorders. The episodes of depression, mania or hypomania may result from the disturbances in endogenous biological timing. In this review, we have summarized the literature data obtained in animal models or in the patients with affective pathology, in which the connection between the function of sleep and depression was demonstrated. Specifically, we highlight the mechanisms underlying sleep dysfunction during depression (imbalance of circadian rhythms, melatonin metabolism and mechanisms of neuroinflammatory dysregulation) and provide an evidence for the link between sleep function and depression (sleep disturbances during depressive episodes, the effects of pharmacotherapy, chronotherapy, the effect of sleep deprivation, comorbidity of obstructive sleep apnea and depression).

scholarly journals Gambaran deteksi dini masalah mental emosional anak taman kanak-kanak

2020 ◽  
Vol 2 (2) ◽  
pp. 325-329
Author(s):  
Siti Rohani ◽  
Rini Wahyuni
Keyword(s):  
Emotional Disorders ◽  
Univariate Analysis ◽  
Emotional Problems ◽  
Sampling Technique ◽  
Autism Spectrum ◽  
Hyperactivity Disorder ◽  
Descriptive Research ◽  
Role Of Parents ◽  
Quantitative Descriptive

Mental and emotional disorders are one type of developmental disorder in children. These disorders are all diagnosed with mental disorders and begin in childhood, including Attention Deficit Hyperactivity Disorder (ADHD), Tourette syndrome, behavior disorders, mood disorders and anxiety, autism spectrum disorders, and substance use disorders. This study aims to determine the description of Early Detection of Children's Mental Emotional Problems in the TK Aisyiyah  Pringsewu Regency in 2019. The method used in this research is the univariate analysis method. This study used a quantitative descriptive research design. The population in this study were all children in Aisyiyah Pringsewu Kindergarten, Pringsewu Regency, as many as 80 children. The sampling technique in this study using total sampling. Univariate data analysis. Univariate analysis found that 32 respondents (40 percent) were male and 48 female respondents (60 percent), and 14 respondents (17.5 percent) who experienced emotional mental problems. 66 respondents (82.5 percent) did not experience mental-emotional problems. The results of this study can be used as input and additional knowledge to parents and school parents about the importance of the role of parents, especially mothers, families and the environment in the process of children's mental development.

An Adolescent Girl Experiments with Sexuality: Rain (Christine Jeffs, 2001)

2018 ◽  
Author(s):  
Alistair Fox
Keyword(s):  
New Zealand ◽  
Adolescent Girl ◽  
Emotional Problems ◽  
Human Condition ◽  
The Core ◽  
Parental Neglect ◽  
The Human Condition

The analysis in this chapter focuses on Christine Jeffs’s Rain as evidence of a shift that had occurred in New Zealand society whereby puritan repression is no longer perceived as the source of emotional problems for children in the process of becoming adults, but rather its opposite – neoliberal individualism, hedonism, and the parental neglect and moral lassitude it had promoted. A comparison with Kirsty Gunn’s novel of the same name, upon which the adaptation is based, reveals how Jeffs converted a poetic meditation on the human condition into a cinematic family melodrama with a girl’s discovery of the power of her own sexuality at the core.

Does a Ribosome Really Read? On the Cognitive Roots and Heuristic Value of Linguistic Metaphors in Molecular Genetics. Part 2

2020 ◽  
Vol 63 (2) ◽  
pp. 46-62
Author(s):  
Suren T. Zolyan
Keyword(s):  
Information Processing ◽  
Genetic Information ◽  
Formal Organization ◽  
Dual Nature ◽  
Reading Frame ◽  
The Core ◽  
Genetic Information Processing ◽  
Cognitive Frame ◽  
Effective Instrument

We discuss the role of linguistic metaphors as a cognitive frame for the understanding of genetic information processing. The essential similarity between language and genetic information processing has been recognized since the very beginning, and many prominent scholars have noted the possibility of considering genes and genomes as texts or languages. Most of the core terms in molecular biology are based on linguistic metaphors. The processing of genetic information is understood as some operations on text – writing, reading and editing and their specification (encoding/decoding, proofreading, transcription, translation, reading frame). The concept of gene reading can be traced from the archaic idea of the equation of Life and Nature with the Book. Thus, the genetics itself can be metaphorically represented as some operations on text (deciphering, understanding, code-breaking, transcribing, editing, etc.), which are performed by scientists. At the same time linguistic metaphors portrayed gene entities also as having the ability of reading. In the case of such “bio-reading” some essential features similar to the processes of human reading can be revealed: this is an ability to identify the biochemical sequences based on their function in an abstract system and distinguish between type and its contextual tokens of the same type. Metaphors seem to be an effective instrument for representation, as they make possible a two-dimensional description: biochemical by its experimental empirical results and textual based on the cognitive models of comprehension. In addition to their heuristic value, linguistic metaphors are based on the essential characteristics of genetic information derived from its dual nature: biochemical by its substance, textual (or quasi-textual) by its formal organization. It can be concluded that linguistic metaphors denoting biochemical objects and processes seem to be a method of description and explanation of these heterogeneous properties.

Exploring the Mechanism of Lingzhu San in Treating Febrile Seizures by Using Network Pharmacology

2020 ◽  
Vol 23 ◽  
Author(s):  
Xiao Zhou ◽  
Xiao-Fei Zhang ◽  
Dong-Yan Guo ◽  
Yan-Jun Yang ◽  
Lin Liu ◽  
...  
Keyword(s):  
Febrile Seizures ◽  
Network Pharmacology ◽  
Biological Processes ◽  
Active Compounds ◽  
Potential Core ◽  
R Language ◽  
The Core ◽  
Multiple Factors ◽  
Therapeutic Mechanism

Objective: Lingzhu San (LZS) is a traditional Chinese medicine (TCM) prescription which can be effective in treating febrile seizures (FS) and has few researches on the mechanisms. In order to better guide the clinical use of LZS, we used the research ideas and methods of network pharmacology to find the potential core compounds, targets and pathways of LZS in the complex TCM system for the treatment of FS, and predict the mechanism. Materials and Methods: Databases such as BATMAN, TCMSP, TCMID, and SWISS TARGET are used to mine the active compounds and targets of LZS, and the target information of FS was obtained through GENECARDS and OMIM. Using Venny2.1.0 and Cytoscape software to locked the potential core compounds and targets of FS. The R language and ClusterProfiler software package were adopt to enrich and analyze the KEGG and GO pathways of the core targets and the biological processes and potential mechanisms of the core targets were revealed. Results: 187 active compounds and 2113 target proteins of LZS were collected. And 38 potential core compounds, 35 core targets and 775 metabolic and functional pathways were screened which involved in mediating FS. Finally, the role of the core compounds, targets and pivotal pathways of LZS regulated FS in the pathogenesis and therapeutic mechanism of FS was discussed and clarified. Conclusions: In this paper, the multi-compounds, multi-targets and multi-pathways mechanism of LZS in the treatment of FS was preliminarily revealed through the analysis of network pharmacology data, which is consistent with the principle of multi-compounds compatibility of TCM prescriptions and unified treatment of diseases from multiple angles, and it provides a new way for TCM to treat complex diseases caused by multiple factors.

Acid ceramidase, a double-edged sword in cancer aggression: A minireview

2020 ◽  
Vol 20 ◽  
Author(s):  
Helen Shiphrah Vethakanraj ◽  
Niveditha Chandrasekaran ◽  
Ashok Kumar Sekar
Keyword(s):  
Cell Fate ◽  
Cancer Progression ◽  
Potential Role ◽  
Tumour Progression ◽  
Acid Ceramidase ◽  
The Core ◽  
The Past ◽  
Sphingosine 1 Phosphate ◽  
Key Enzyme

: Acid ceramidase (AC), the key enzyme of the ceramide metabolic pathway hydrolyzes pro-apoptotic ceramide to sphingosine, which by the action of sphingosine-1-kinase is metabolized to mitogenic sphingosine-1-phosphate. The intracellular level of AC determines ceramide/sphingosine-1-phosphate rheostat which in turn decides the cell fate. The upregulated AC expression during cancerous condition acts as a “double-edged sword” by converting pro-apoptotic ceramide to anti-apoptotic sphingosine-1-phosphate, wherein on one end, the level of ceramide is decreased and on the other end, the level of sphingosine-1-phosphate is increased, thus altogether aggravating the cancer progression. In addition, cancer cells with upregulated AC expression exhibited increased cell proliferation, metastasis, chemoresistance, radioresistance and numerous strategies were developed in the past to effectively target the enzyme. Gene silencing and pharmacological inhibition of AC sensitized the resistant cells to chemo/radiotherapy thereby promoting cell death. The core objective of this review is to explore AC mediated tumour progression and the potential role of AC inhibitors in various cancer cell lines/models.

The Fox Diet

2018 ◽  
Author(s):  
Yochai Benkler ◽  
Robert Faris ◽  
Hal Roberts
Keyword(s):  
First Year ◽  
Right Wing ◽  
Justice Department ◽  
Fox News ◽  
The Core ◽  
Deep State ◽  
Media Ecosystem ◽  
Conservative Media ◽  
The Right

This chapter focuses on the role of the dominant player in conservative media, Fox News, during the first year of Donald Trump’s presidency. It looks at three case studies to illustrate how Fox News used its position at the core of the right-wing media ecosystem repeatedly to mount propaganda attacks in support of Trump: the Michael Flynn firing in March 2017, when Fox adopted the “deep state” framing of the entire controversy; the James Comey firing and Robert Mueller appointment in May 2017; when Fox propagated the Seth Rich murder conspiracy; and in October and November, when the arrests of Paul Manafort and guilty plea of Flynn seemed to mark a new level of threat to the president, Fox reframed the Uranium One story as an attack on the integrity of the FBI and Justice Department officials in charge of the investigation.

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