Antimicrobial Activity of New Phorbins from Jatropha curcas Linn. (Euphorbiaceae) Leaves

2011 ◽  
Vol 66 (9-10) ◽  
pp. 441-446
Author(s):  
Irene M. Villaseñor ◽  
Flerida A. Cariño
Keyword(s):  
Escherichia Coli ◽  
Saccharomyces Cerevisiae ◽  
Antimicrobial Activity ◽  
Jatropha Curcas ◽  
Methanol Extract ◽  
Trichophyton Mentagrophytes ◽  
Spectroscopic Methods ◽  
Pheophorbide A ◽  
Mycobacterium Phlei ◽  
Crude Methanol Extract

The crude methanol extract of Jatropha curcas leaves exhibited activity against Staphylococcus aureus, Bacillus subtilis, Mycobacterium phlei, Candida albicans, and Trichophyton mentagrophytes but was inactive against Escherichia coli, Pseudomonas aeruginosa, and Saccharomyces cerevisiae. In a bioassay-directed fractionation, two new phorbins were isolated and analysed by spectroscopic methods. Isolate 1 was characterized as an analogue of pheophytin b with a phytyl moiety containing three double bonds which are at positions P2/P3, P6/P7, and P10/P11. Compound 2 was characterized as methyl pheophorbide a with 132-OH and 17- and 171-CH3 moieties. It is active against Serratia marcescens.

scholarly journals Spectral Studies and Bactericidal, Fungicidal, Insecticidal and Parasitological Activities of Organotin(IV) Complexes of Thio Schiff Bases Having no Donor Atoms

1995 ◽  
Vol 2 (6) ◽  
pp. 297-309 ◽  
Author(s):  
Mala Nath ◽  
Savita Goyal
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Schiff Bases ◽  
Thermal Studies ◽  
Far Infrared ◽  
Trichophyton Mentagrophytes ◽  
Spectral Studies ◽  
No Donor

Twelve new organotin(IV) complexes of the type RnSnLm [where n = 3, m = 1, R = CH3 or C6H5 ; n = 2, m = 2, R = C6H5 or C4H9 ; L = anion of Schiff bases derived from the condensation of 2-amino-5-(o -anisyl)-l,3,4-thiadiazole with salicylaldehyde (HL-1), 2- hydroxynaphthaldehyde (HL-2) and 2-hydroxyacetophenone (HL-3)] have been synthesized and characterized by elemental analysis, molar conductances, electronic, infrared, far-infrared, H1 NMR and S119n Mössbauer spectral studies. Thermal studies of two complexes, viz., Ph3Sn (L-1) and Ph2Sn(L-2)2 have been carried out in the temperature range 25-1000∘C using TG, DTG and DTA techniques. All these complexes decompose gradually with the formation of SnO2 as an end product. In vitro antimicrobial activity of the Schiff bases and their complexes has also been determined against Streptococcus faecalis, Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus Penicillin resistance (2500 units), Candida albicans, Cryptococcus neoformans, Sporotrichum schenckii, Trichophyton mentagrophytes and Aspergillus fumigatus. The Schiff bases (HL-1), (HL-2) and the organotin(IV) compounds have also been tested against various important herbicidal, fungicidal, insecticidal species and also for parasitological activity against freeliving nematode.

scholarly journals Antimicrobial properties of ZnO nanoparticles incorporated in polyurethane varnish

2011 ◽  
Vol 5 (1) ◽  
pp. 41-45 ◽  
Author(s):  
Dusan Zvekic ◽  
Vladimir Srdic ◽  
Maja Karaman ◽  
Milan Matavulj
Keyword(s):  
Escherichia Coli ◽  
Saccharomyces Cerevisiae ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Zno Nanoparticles ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
Plate Test ◽  
Sacharomyces Cerevisiae

The antimicrobial effect of the ZnO nanoparticles dispersed in polyurethane varnishes was investigated. Antimicrobial activity was evaluated against three bacteria (Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa) and one strain fungi (Sacharomyces cerevisiae) by the 'pour-plate' test. It was shown that the ZnO nanoparticles efficiently inhibit growth of the colonies of Staphylococcus aureus, Pseudomonas aeruginosa and Saccharomyces cerevisiae, but their activity against Escherichia coli was found to be questionable suggesting more detailed research.

scholarly journals ANTIMICROBIAL ACTIVITY OF METHANOL EXTRACT FROM STEM BARK OF Cinnamomum sintoc

2017 ◽  
Vol 17 (2) ◽  
pp. 77
Author(s):  
Nurdin Saidi ◽  
Hira Helwati ◽  
Lailatul Qhadariah Lubis ◽  
Muhammad Bahi
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Methanol Extract ◽  
Stem Bark ◽  
Dilution Method ◽  
Agar Dilution Method ◽  
E Coli ◽  
Paper Disk ◽  
Agar Dilution

Antimicrobial activity of methanol extract from stem bark of Cinnamomum sintoc has been evaluated against Candida albicans, Staphylococcus aureus and Escherichia coli. The extraction of compound was carried out by maceration, then isolation by column chromatograph, which yielded five (5) subfractions (A-E). Activity against fungus C. albicans, S. aureus bacteria dan E. coli using agar dilution method in paper disk. Methanol extract was not potent against antifungal activity but shows antibacterial activity with medium category. Subfraction C showed that antibacterial activity against S. aureus and E. coli with weak category, but subfractions D and E did not show any activity.

scholarly journals Antimicrobic activity concept of water extract of plants Galega orientalis (Lam.)

2018 ◽  
Vol 20 (87) ◽  
pp. 122-125
Author(s):  
L.M. Darmohray ◽  
B.V. Gutyj ◽  
О.О. Darmohray
Keyword(s):  
Escherichia Coli ◽  
Saccharomyces Cerevisiae ◽  
Antimicrobial Activity ◽  
Aqueous Extract ◽  
Micrococcus Luteus ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative ◽  
Pure Cultures ◽  
Galega Orientalis

It was first conducted testing on antimicrobial activity of Galega orientalis (La) on the growth pure cultural of bacteria gram positive (Micrococcus luteus), gram negative (Escherichia coli XL1, DH5) and yeasts (Saccharomyces cerevisiae W303). The material for the study was dried vegetative mass Galega orientalis (Lam) in the phase of budding and early flowering. In experiment used medium «Endo» for gram negative, medium LB for gram positive and gram negative, and suslo agar for yeasts. As a result of the experiment was revealed that 20% concentration of aqueous extract of this plant had inhibitory effects on the growth of pure cultures of bacteria and yeast. Antimicrobial effect of this drug on the growth of gram-negative bacteria (Escherichia coli XL1, DH5) were within 20.0–30.0% (P < 0.001), gram-positive bacteria (M. Luteus) – 12.0% (P < 0.05) and yeast (S. cerevisiae W303) – 30.5% (P < 0.01) compared with control. It should be noted that in all cases the addition of the drug Galega orientalis (La) did not alter the morphology of colonies (colony size) test strains. The questions of search the new antimicrobial agents, include natural origin, is very actual during last years. Increasing microbiological pure of eating products, feed grinders, veterinarian preparations are one of the urgent task of Scientifics and industrials. It has proved the influence of different concentrations of aqueous extract of this culture on the growth of pure cultures of gram-positive and gram-negative bacteria and yeast. Install antimicrobial influence 20–30% concentrations of preparation on the bacteries growth (Escherichia coli XL1, DH5). Bacterial action of preparation on the bacteries (Micrococcus luteus) and yeasts (Saccharomyces cerevisiae W303) were lower. It was described the prospects for further investigation of this problem. It has proved possible relationship between the antimicrobial activity of the extract of this plant and bloating of the rumen in ruminants.

Synthesis of Novel Tetra-Substituted Pyrazole Derivatives from 2,3- Furandione

2019 ◽  
Vol 16 (11) ◽  
pp. 891-897 ◽  
Author(s):  
Hasan Genç ◽  
Volkan Taşdemir ◽  
İsrafil Tozlu ◽  
Erdal Ögün
Keyword(s):  
Escherichia Coli ◽  
Saccharomyces Cerevisiae ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Solid State ◽  
Carboxylic Acid ◽  
Micrococcus Luteus ◽  
Antimicrobial Activities ◽  
Pyrazole Derivatives ◽  
Gram Positive Bacteria

Synthesis of pyrazole-3-carboxylic acid was progressed via two different protocols, one of which is solid state. Pyrazole-3-carboxylic acid was converted into different derivatives such as ester, urea, amide and nitrile. The amide compound was converted to nitrile using SOCl2 and DMF. Solid state heating of carboxylic acid gave decarboxylated product. Cyclization of tetra-substituted pyrazole with hydrazines resulted in pyrazolopyridazinones. The antimicrobial activities of the synthesized pyrazole derivatives against Bacillus cereus, Escherichia coli, Micrococcus luteus, Staphylococcus aureus, and Saccharomyces cerevisiae were evaluated. One of the pyrazole derivatives which possess nitro group showed antimicrobial activity in only B. cereus, a Gram-positive bacteria, with an MIC of 128 μg/mL.

DL-S-TRIFLUOROMETHYLHOMOCYSTEINE, A NOVEL INHIBITOR OF MICROBIAL GROWTH

1966 ◽  
Vol 12 (1) ◽  
pp. 143-148 ◽  
Author(s):  
Walter A. Zygmunt ◽  
Peter A. Tavormina
Keyword(s):  
Escherichia Coli ◽  
Saccharomyces Cerevisiae ◽  
Natural Products ◽  
Candida Albicans ◽  
Mycobacterium Smegmatis ◽  
Microbial Growth ◽  
Leuconostoc Mesenteroides ◽  
Geotrichum Candidum ◽  
Candida Lipolytica ◽  
Mycobacterium Phlei

DL-S-Trifluoromethylhomocysteine was tested for its effect on the growth of a wide variety of microorganisms. The compound, trifluoromethylhomocysteine, markedly inhibited growth of Mycobacterium smegmatis, Mycobacterium phlei, Candida lipolytica, Saccharomyces cerevisiae, Geotrichum candidum, and to a lesser extent, Candida albicans and Escherichia coli. In M. smegmatis, glutamine, methionine, norleucine, norvaline, and certain natural products reversed this antagonism. Utilization of DL-methionine by Leuconostoc mesenteroides, a culture which requires preformed methionine, was not inhibited by trifluoromethylhomocysteine. The compound was also inactive as a replacement for methionine in growth of L. mesenteroides.

scholarly journals Antimicrobial Activity Jangjingki (Oxalis corniculata L.) Against The Growth Of Staphylococcus Aureus, Escherichia Coli, and Candida Albicans

2021 ◽  
Vol 4 (1) ◽  
pp. 1-11
Author(s):  
Misrahanum Misrahanum ◽  
Syarifah Dhea Almunawwarah ◽  
Hira Helwati ◽  
Hilda Maysarah ◽  
Sadli Sadli
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Methanol Extract ◽  
Water Soluble ◽  
Test Results ◽  
Soluble Extract ◽  
E Coli ◽  
Activity Test ◽  
Water Soluble Extract

Jangjingki (Oxalis corniculata L.) is a plant from Oxalidaceae that has potential as a natural antimicrobial agent. The purpose of this research is to see the antimicrobial activity of methanol extract of jangjingki against the growth of Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, and Candida albicans ATCC 10231. The thick extract of jangjingki was obtained by the maceration method with methanol solvent. At the same time, the antimicrobial activity test on S. aureus and E. Coli bacteria was carried out using the hole diffusion method. The simplicia characterization showed 7.17% water, 9.68% of total ash, 11.67% water-soluble extract, and 9.17% of the ethanol-soluble section. At the same time, the methanol extract of jangjingki characterization showed 22.5% of water, 10.16% of total ash, 55.83% water-soluble extract, and 62.91% of the ethanol-soluble section. Phytochemical test results showed that the methanol extract of jangjingki contains alkaloids, saponins, flavonoids, tannins, and steroids. The results of the antimicrobial activity test with variations in the concentration of jangjingki methanol extract 15, 20, 30, and 40% on S. aureus and E. Coli bacteria showed growth inhibition activity of these two bacteria, the largest diameter of the inhibition zone was formed when the extract was given a concentration of 40% with a diameter of the area. Resistance of 8,07 mm and 11 mm, respectively. Meanwhile, the test results of inhibition of growth of the fungus C. Albicans by presenting variations in the concentration of jangjingki methanol extract of 5, 10, 15, and 20% could not inhibit the growth fungus C. Albicans.

scholarly journals PENAPISAN DAN KARAKTERISASI PARSIAL SENYAWA ANTIMIKROBA DARI SIPUT BAKAU DAN PROFIL KROMATOGRAFI LAPIS TIPIS FRAKSI AKTIF

2006 ◽  
Vol 12 (1) ◽  
pp. 63-68
Author(s):  
Alimuddin Ali ◽  
Yusminah Hala ◽  
Darminto Darminto
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Candida Albicans ◽  
Bacterial Infection ◽  
Bacterial Growth ◽  
Methanol Extract ◽  
Antimicrobial Effect ◽  
Inhibition Zone ◽  
Mangrove Snail

Mangrove snail is one of the animal medicines used againts bacterial infection, however, the scientific basic of the activity still void. The aim of this research were to investigate the antimicrobial effect of mangrove snail as the primary step to identify an antimicrobial activity and find out substances responsible to this activity. The study was conducted by collecting 4 snail samples. Extract were made be maceration of methanol and followed by chloroform and n-butanol partision, respectively. Antimicrobial activity has been done using Salmonella typhii, Staphylococcus aureus, Escherichia coli and fungi Candida albicans. The result showed that these mangrove snail capable inhibit bacterial growth either Gram positive or negative, but can not inhibition fungi. Methanol extract of Terebralia sulcata showed inhibition zone has the Rf 0.27, whereas chloroform fractions of Charonia sp. has 6 spots by bioautographic. Two out of six spots showed inhibition zone with Rf 0.16 and Rf 0.4. Methanol extract of N. birmanica has inhibit with Rf 0.56. One spots with Rf 0.42 unclear as inhibition zone suggested negative. Then the methanol extract of Telescopium telescopium with Rf 0.34 showing inhibition zone.

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