Recombination Spaces, Metrics, and Pretopologies

Author(s):  
Bärbel M. R. Stadler ◽  
Peter F. Stadler ◽  
Max Shpak ◽  
Günther .P. Wagner

The topological features of genotype spaces given a genetic operator have a substantial impact on the course of evolution. We explore the structure of the recombination spaces arising from five different unequal crossover models in the context of pretopological spaces. We show that four of the models are incompatible with metric distance measures due to a lack of symmetry.

2019 ◽  
Author(s):  
Peter Wills ◽  
François G. Meyer

AbstractComparison of graph structure is a ubiquitous task in data analysis and machine learning, with diverse applications in fields such as neuroscience [1], cyber security [2], social network analysis [3], and bioinformatics [4], among others. Discovery and comparison of structures such as modular communities, rich clubs, hubs, and trees in data in these fields yields insight into the generative mechanisms and functional properties of the graph.Often, two graphs are compared via a pairwise distance measure, with a small distance indicating structural similarity and vice versa. Common choices include spectral distances (also known asλdistances) and distances based on node affinities (such asDeltaCon[5]). However, there has of yet been no comparative study of the efficacy of these distance measures in discerning between common graph topologies and different structural scales.In this work, we compare commonly used graph metrics and distance measures, and demonstrate their ability to discern between common topological features found in both random graph models and empirical datasets. We put forward a multi-scale picture of graph structure, in which the effect of global and local structure upon the distance measures is considered. We make recommendations on the applicability of different distance measures to empirical graph data problem based on this multi-scale view. Finally, we introduce the Python libraryNetCompwhich implements the graph distances used in this work.


2016 ◽  
Vol 25 (2) ◽  
pp. 221-237 ◽  
Author(s):  
Leila Baccour ◽  
Adel M. Alimi ◽  
Robert I. John

AbstractWe present some similarity and distance measures between intuitionistic fuzzy sets (IFSs). Thus, we propose two semi-metric distance measures between IFSs. The measures are applied to classification of shapes and handwritten Arabic sentences described with intuitionistic fuzzy information. The experimental results permitted to do a comparative analysis between intuitionistic fuzzy similarity and distance measures, which can facilitate the selection of such measure in similar applications.


Author(s):  
D.W. Andrews ◽  
F.P. Ottensmeyer

Shadowing with heavy metals has been used for many years to enhance the topological features of biological macromolecular complexes. The three dimensional features present in directionaly shadowed specimens often simplifies interpretation of projection images provided by other techniques. One difficulty with the method is the relatively large amount of metal used to achieve sufficient contrast in bright field images. Thick shadow films are undesirable because they decrease resolution due to an increased tendency for microcrystalline aggregates to form, because decoration artefacts become more severe and increased cap thickness makes estimation of dimensions more uncertain.The large increase in contrast provided by the dark field mode of imaging allows the use of shadow replicas with a much lower average mass thickness. To form the images in Fig. 1, latex spheres of 0.087 μ average diameter were unidirectionally shadowed with platinum carbon (Pt-C) and a thin film of carbon was indirectly evaporated on the specimen as a support.


2020 ◽  
Author(s):  
Jakob Dahl ◽  
Xingzhi Wang ◽  
Xiao Huang ◽  
Emory Chan ◽  
Paul Alivisatos

<p>Advances in automation and data analytics can aid exploration of the complex chemistry of nanoparticles. Lead halide perovskite colloidal nanocrystals provide an interesting proving ground: there are reports of many different phases and transformations, which has made it hard to form a coherent conceptual framework for their controlled formation through traditional methods. In this work, we systematically explore the portion of Cs-Pb-Br synthesis space in which many optically distinguishable species are formed using high-throughput robotic synthesis to understand their formation reactions. We deploy an automated method that allows us to determine the relative amount of absorbance that can be attributed to each species in order to create maps of the synthetic space. These in turn facilitate improved understanding of the interplay between kinetic and thermodynamic factors that underlie which combination of species are likely to be prevalent under a given set of conditions. Based on these maps, we test potential transformation routes between perovskite nanocrystals of different shapes and phases. We find that shape is determined kinetically, but many reactions between different phases show equilibrium behavior. We demonstrate a dynamic equilibrium between complexes, monolayers and nanocrystals of lead bromide, with substantial impact on the reaction outcomes. This allows us to construct a chemical reaction network that qualitatively explains our results as well as previous reports and can serve as a guide for those seeking to prepare a particular composition and shape. </p>


10.28945/2926 ◽  
2005 ◽  
Author(s):  
James N. Morgan ◽  
Craig A. VanLengen

The divide between those who have computer and Internet access and those who do not appears to be narrowing, however overall statistics may be misleading. Measures of computer availability in schools often include cases where computers are only available for administration or are available only on a very limited basis (Gootman, 2004). Access to a computer and the Internet outside of school helps to reinforce student learning and emphasize the importance of using technology. Recent U.S. statistics indicate that ethnic background and other demographic characteristics still have substantial impact on the availability and use of computers by students outside of the classroom. This paper examines recent census data to determine the impact of the household on student computer use outside of the classroom. Encouragingly, the findings of this study suggest that use of a computer at school substantially increases the chance that a student will use a computer outside of class. Additionally, this study suggests that computer use outside of the classroom is positively and significantly impacted by being in a household with adults who either use a computer at work or work in an industry where computers are extensively used.


2018 ◽  
Vol 77 (4) ◽  
pp. 222-229 ◽  
Author(s):  
A. V. Paranin ◽  
A. B. Batrashov

The article compares the results of calculation of the finite element simulation of current and temperature distribution in the scale model of the DC catenary with the data of laboratory tests. Researches were carried on various versions of the structural design of catenary model, reflecting the topological features of the wire connection, characteristic of the DC contact network. The proportions of the cross-sectional area of the scaled model wires are comparable to each other with the corresponding values for real DC catenary. The article deals with the operating conditions of the catenary model in the modes of transit and current collection. When studying the operation of the scale catenary model in the transit mode, the effect of the structural elements on the current distribution and heating of the wires was obtained. Within the framework of the scale model, theoretical assumptions about the current overload of the supporting cable near the middle anchoring have been confirmed. In the current collection mode, the experimental dependences of the current in the transverse wires of the scale model are obtained from the coordinate of the current collection point. Using the model it was experimentally confirmed that in the section of the contact wire with local wear, not only the temperature rise occurs but also the current redistribution due to the smaller cross section. Thus, the current share in other longitudinal wires of the scale model increases and their temperature rises. Scale and mathematical models are constructed with allowance for laboratory clamps and supporting elements that participate in the removal of heat from the investigated wires. Obtained study results of the scale model allow to draw a conclusion about the adequacy of the mathematical model and its correspondence to the real physical process. These conclusions indicate the possibility of applying mathematical model for calculating real catenary, taking into account the uneven contact wear wire and the armature of the contact network.


2020 ◽  
Vol 96 (3s) ◽  
pp. 169-174
Author(s):  
Ю.М. Герасимов ◽  
Н.Г. Григорьев ◽  
А.В. Кобыляцкий ◽  
Я.Я. Петричкович

Рассматриваются архитектурные, схемотехнические и конструктивно-топологические особенности асинхронного радиационно стойкого ОЗУ 1657РУ2У емкостью 16 Мбит с организацией (1Мx16)/(2Mx8), изготавливаемого по коммерческой КМОП-технологии объемного кремния уровня 130 нм. СБИС ОЗУ нечувствительна к эффекту «защелкивания», имеет повышенные дозовую стойкость и сбоеустойчивость при воздействии отдельных ядерных частиц (ОЯЧ), протонов и нейтронов (ТЧ). The paper highlights architectural, schematic and topological features of the radiation hardened 16 Mbit CMOS SRAM with configurable organization 1Mx16/2Mx8, which is immune to latch-up and with improved total dose and heavy particles tolerance.


Stanovnistvo ◽  
1999 ◽  
Vol 37 (1-4) ◽  
pp. 73-92
Author(s):  
Jelena Antonovic

Mass migration to urban areas constitutes the basic direct factor of the decline in rural population of Yugoslavia in the second half of the 20th century. Due to the characteristic migration patterns by age and sex, they have had a substantial impact on the change in age structure of rural population towards rapid demographic ageing. By inducing decline in fertility and an increase in mortality, the newly formed age structure is increasingly becoming one of the basic factors to further decline in population, or even the major factor to rural depopulation in the majority of regions. The paper analyzes changes in age structure of rural population in the FR of Yugoslavia and across its republics and provinces during the period from 1961 to 1991. The conditions prevailing during the last census (1991) are particularly highlighted. The author points to distinct differences in ageing of urban versus rural populations, and considerable regional differences at the achieved level of demographic age. Based on the main demographic age indicators (the share of five-year and larger age groups, average age, ageing index and movement in major age-specific contingents), the author concludes that the process of population ageing had taken place in both rural and urban populations, but was more intensive in villages (higher share of the aged, higher index of ageing and higher average age) during the period under review. The author points to distinct ageing of rural population in all republics and provinces. It was most prominent in central Serbia and Vojvodina, while being quite slow in Kosovo and Metohia and recorded mainly in between the last two censuses (1981-1991). Likewise, Kosovo and Metohia constitute the only major region of Yugoslavia in which rural population in 1991 is still demographically younger than the population in urban settlements. Rural versus urban population ageing was much more intensive in other major regions of the country, both from the base and from the apex of the age pyramid. In view of the minimal differences in fertility and mortality levels by type of settlement (particularly in central Serbia and Vojvodina), the author argues that the inherited age structure constitutes the main cause of rapid acceleration in rural population ageing in low fertility regions.


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