scholarly journals Dimensionless parameter predicts bacterial prodrug success

2022 ◽  
Vol 18 (1) ◽  
Author(s):  
Brandon Alexander Holt ◽  
McKenzie Tuttle ◽  
Yilin Xu ◽  
Melanie Su ◽  
Joachim J Røise ◽  
...  
2000 ◽  
Vol 42 (1-2) ◽  
pp. 319-324 ◽  
Author(s):  
H. Rubin ◽  
A. Rabideau

This study presents an approximate analytical model, which can be useful for the prediction and requirement of vertical barrier efficiencies. A previous study by the authors has indicated that a single dimensionless parameter determines the performance of a vertical barrier. This parameter is termed the barrier Peclet number. The evaluation of barrier performance concerns operation under steady state conditions, as well as estimates of unsteady state conditions and calculation of the time period requires arriving at steady state conditions. This study refers to high values of the barrier Peclet number. The modeling approach refers to the development of several types of boundary layers. Comparisons were made between simulation results of the present study and some analytical and numerical results. These comparisons indicate that the models developed in this study could be useful in the design and prediction of the performance of vertical barriers operating under conditions of high values of the barrier Peclet number.


Author(s):  
A. Cheshomi ◽  
M. Moradizadeh

The wear of cutting blades during the preparation of building stones is an inevitable issue that occurs due to the contact of the blade with rock components. The present study aims to investigate the feasibility of proposing experimental relations of strength parameters and mineralogical hardness with Cerchar and LCPC tests. For this purpose, 18 samples of granite building stones were selected and Equivalent Quartz Content (EQC), compressive and Brazilian tensile strength (UCS and BTS), Cerchar, and LCPC abrasivity indices (CAI and LAC) were determined. The results showed the lack of any significant relationship between strength and abrasion properties. However, when evaluating the simultaneous impact of EQC and UCS using the rock abrasion index (RAI=UCS×EQC), significant valid empirical relationships between RAI-CAI and RAI-LAC were derived. To investigate the simultaneous effect of UCS, BTS, and EQC, a dimensionless parameter, i.e. modified rock abrasion index (MRAI=(UCSBTS)×EQC) was introduced. Moreover, it was found that the empirical relationship between MRAI-CAI was more significant and valid than the previous relations. Verification of the proposed relationship with the values of other researchers and 6 new samples for estimating CAI and LAC based on UCS, BTS, and EQC was found to be highly accurate for granite building stones.


1970 ◽  
Vol 39 (2) ◽  
pp. 65-70 ◽  
Author(s):  
MC Raju ◽  
SVK Varma ◽  
PV Reddy ◽  
Sumon Saha

The effect of small uniform magnetic field on separation of a binary mixture for the case of a fully developed natural convection between two heated inclined plates has been investigated in this paper. Neglecting the induced electric field the equations governing the motion, temperature and concentration are solved by simple perturbation technique, in terms of dimensionless parameter measuring buoyancy force. The expressions for velocity, temperature and concentration are obtained. The effects of Hartmann number (M), thermal diffusion number (td), the buoyancy force parameter (N) and the inclination angle (ψ) of the plates with the horizontal are studied on the flow and heat transfer quantities. Keywords: Natural convection, thermal diffusion, magnetic field, incompressible fluid, binary mixture. doi:10.3329/jme.v39i2.1848 Journal of Mechanical Engineering, Vol. ME39, No. 2, Dec. 2008 65-70


1980 ◽  
Vol 102 (3) ◽  
pp. 344-349 ◽  
Author(s):  
M. A. Hoffman ◽  
R. K. Takahashi ◽  
R. D. Monson

Experiments have been performed to determine the length for convergence or closure of a vertical, hollow annular water jet due to the action of surface tension forces. The data agree well with theoretical predictions up to the maximum velocity where reliable data could be obtained (4.4 m/s). These experiments extend the range of confirmation of the theories in terms of the dimensionless parameter, Nc ≡ We/Fr2, from about 0.01 to over 100. The stability of the annular jet subjected to natural and external disturbances is also discussed briefly. Finally the results of a series of experiments on the flow spreading or splitting due to the presence of wedge-shaped obstacles in the path of the annular jet flow are presented.


1976 ◽  
Vol 98 (1) ◽  
pp. 24-29 ◽  
Author(s):  
D. L. Davidson ◽  
J. Lankford

The techniques of selected area electron channeling and positive replica examination have been used to study the plastic zones attending fatigue crack propagation in 304 SS, 6061-T6 aluminum alloy, and Fe-3Si steel. These observations allowed the strain distribution at the crack tip to be determined. The results indicate that the concepts of a monotonic and a cyclic plastic zone are essentially correct, with the strains at demarcation between these two zones being 3 to 6 percent. Strain distribution varies as r−1/2 in the cyclic zone and as ln r in the monotonic plastic zone. The strain distributions for all materials studied may be made approximately coincident by using a dimensionless parameter related to distance from the crack tip.


2018 ◽  
Vol 115 (32) ◽  
pp. 8116-8118 ◽  
Author(s):  
Daniel Floryan ◽  
Tyler Van Buren ◽  
Alexander J. Smits

Many swimming and flying animals are observed to cruise in a narrow range of Strouhal numbers, where the Strouhal number St=2fA/U is a dimensionless parameter that relates stroke frequency f, amplitude A, and forward speed U. Dolphins, sharks, bony fish, birds, bats, and insects typically cruise in the range 0.2<St<0.4, which coincides with the Strouhal number range for maximum efficiency as found by experiments on heaving and pitching airfoils. It has therefore been postulated that natural selection has tuned animals to use this range of Strouhal numbers because it confers high efficiency, but the reason why this is so is still unclear. Here, by using simple scaling arguments, we argue that the Strouhal number for peak efficiency is largely determined by fluid drag on the fins and wings.


2017 ◽  
Author(s):  
Jian Gu ◽  
Antonio Carlos Fernandes

The influences of Re (Reynolds number) on the response of vortex induced vibration (VIV) have been studied by previous researches, which indicate the influences should not be ignored. However, due to the limitation of experimental facilities and complexity of the cases, the explicit influence of Re on VIV is still not fully known. Meanwhile, the industry standards also do not supply design reference taking account of Re effects quantitatively. In present work, an innovative dimensionless parameter (denoted as “inertia-viscosity”) is proposed to displace the Re in the dimensionless system, in order to clarify the individual effect of Re. With this method, comparing tests are concisely carried out, and the effectiveness and feasibility are demonstrated. Through the comparing of tests, several remarkable results are obtained.


2006 ◽  
Vol 21 (24) ◽  
pp. 1851-1863 ◽  
Author(s):  
T. R. GOVINDARAJAN ◽  
SEÇKIN KÜRKÇÜOǦLU ◽  
MARCO PANERO

We study noncommutative field theories, which are inherently nonlocal, using a Poincaré-invariant regularisation scheme which yields an effective, nonlocal theory for energies below a cutoff scale. After discussing the general features and the peculiar advantages of this regularisation scheme for theories defined in noncommutative spaces, we focus our attention on the particular case when the noncommutativity parameter is inversely proportional to the square of the cutoff, via a dimensionless parameter η. We work out the perturbative corrections at one-loop order for a scalar theory with quartic interactions, where the signature of noncommutativity appears in η-dependent terms. The implications of this approach, which avoids the problems related to uv–ir mixing, are discussed from the perspective of the Wilson renormalisation program. Finally, we remark about the generality of the method, arguing that it may lead to phenomenologically relevant predictions, when applied to realistic field theories.


1985 ◽  
Vol 58 ◽  
Author(s):  
V. Laxmanan

ABSTRACTMicrostructural transitions occurring during solidification processes may be described in terms of three dimensionless parameters, s, p and σC, which include among them various processing variables and relevant material constants. The dimensionless parameter, s, in particular offers a convenient description of both planar-cellular and cell-dendrite transitions. The relationships between σC, s and p predicted by various dendrite growth models have been summarized.


1994 ◽  
Vol 116 (2) ◽  
pp. 97-101
Author(s):  
T. E. Horton ◽  
M. J. Feifarek ◽  
H. Golestanian

A correlation of the hydrodynamic drag force on a cylinder for a periodic motion is demonstrated. The correlation indicates the dependance of the unsteady flow drag coefficient on the wake volume parameter. This parameter is a measure of the volume of flow through the boundary layer and into the wake in a half-cycle. For a laminar boundary layer, this dimensionless parameter is proportional to the Keulegan-Carpenter number and inversely proportional to the square root of the Reynolds number. Using wake volume scaling, drag coefficients were effectively collapsed into a single curve.


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