scholarly journals The Control of Diabetes Mellitus in Coastal Communities in Surabaya Region

2019 ◽  
Vol 15 (1) ◽  
pp. 69-80
Author(s):  
Christina Yuliastuti ◽  
Diyah Arini ◽  
Mufhida Praningtyas Enggar Sari
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Diabetes Control ◽  
Coastal Communities ◽  
Postprandial Blood Glucose ◽  
Diabetic Patients ◽  
Control Measurement ◽  
Control Of Diabetes

Prevention of complications of diabetes mellitus requires good control of diabetes mellitus. Based on Basic Health Research Data of the Ministry of Health, in the end of 2013, the number of diabetic patients in Indonesia had reached 9.1 million and this number continues to grow which in 2030, the number is predicted to reach 21.3 million. This study aimed to identify the paramaters of diabetes mellitus control. This descriptive study involved 30 diabetic patients in coastal communities of Surabaya who were randomly selected. Data collection was undertaken using an observation sheet and diabetes control measurement tools. The data were analyzed descriptively. The results showed that diabetes control were mostly poor based from the indicator of fasting blood glucose level (181.77±68.728) and two hours postprandial blood glucose level (277.07±111.884). Meanwhile, total cholesterol (196.43±60.640), blood pressure (systolic 125±16.969 and diastolic 78±8.469), and Body Mass Index (23,257±3,231) were good. Education on Self Care Management will support the control of diabetes mellitus.

scholarly journals Influence of Patient Characteristics on The Type of Insulin Therapy Obtained by Diabetes Type 2 Outpatient in Denpasar Municipality

2017 ◽  
Vol 1 (2) ◽  
pp. 139
Author(s):  
Luh Putu Febrayana Larasanty ◽  
I GNA. Dewantara Putra ◽  
Rhyce Dewata Sari ◽  
Komang Dede Saputra ◽  
I GA. Gede Minanjaya ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Insulin Therapy ◽  
Glucose Level ◽  
Medical Records ◽  
Fasting Blood Glucose ◽  
Patient Characteristics ◽  
Postprandial Blood Glucose

This study aims to investigate the influence of patient characteristics on the choice of insulin therapy in type 2 diabetes mellitus outpatients in Denpasar municipality. This is a descriptive analysis study using the patient's medical records as research material. Patients who meet inclusion and exclusion criteria are being recorded based on their medical records. Characteristics that are taken are age, gender, fasting blood glucose level (FBG), 2-hour postprandial blood glucose level (2-hours PPG) and HbA1c values of patients. Types of insulin therapy gained from patient medical records and drug use report in pharmacy. Characteristics data and type of insulin analyzed using correlation test to determine the effect of the patient characteristics on the selection of insulin therapy. 43 patients became the research subject. Males gendered patients (72.09%) and the patients aged less than 65 years (90.70%) are the dominant characteristics of the research subjects. The average value of FBG of patients is 212 mg / dL; 2-hours PPG 280 mg / dL and HbA1c 10.1%. There is a correlation between sex, age, HbA1c value and FBG with the type of insulin obtained by patients (p <0.05). Based on the results of statistical tests, age and gender have a strong correlation on insulin choice, HbA1c and FBG level has a moderate influence and 2-hours PPG have a weak correlation. Patient characteristics had an influence on the type of insulin choice for diabetes mellitus type 2 outpatient in the Denpasar municipality.

scholarly journals EFFECT OF AEROBIC EXERCISES AND RESISTANCE TRAINING ON GLUCOSE LEVELS IN TYPE 2 DIABETIC SUBJECTS.

2017 ◽  
Vol 10 (7) ◽  
pp. 360
Author(s):  
Aishwarya Pramod Benkar ◽  
Smita Bhimrao Kanase
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Resistance Training ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Postprandial Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Significant Difference

Objective: Diabetes mellitus is a leading cause of death and disability in the world and its prevalence is predicted to rise to 10% by 2030. Hence, this study is conducted with objectives to find out the effect of aerobic exercises and resisted exercises on blood glucose levels in type 2 diabetes mellitus (T2DM) subjects and to compare the effect of both exercises on blood glucose level.Method: The comparative study was conducted at Krishna Institute of Medical Sciences Deemed University, Physiotherapy department, Karad. 30 participants with age group between 30 and 65 years were taken. Subjects were selected as per inclusion and exclusion criteria. Group A (15) participants were given aerobic exercise on static bicycle, and Group B (15) participants were given resistance training using dumbbells and weight cuffs for 5 days/week for 4 weeks. Diet recommendations were given to every participant.Results: Statistical analysis was performed using paired and unpaired t-test. Analysis showed statistically extremely significant difference in fasting blood glucose level and postprandial blood glucose level in both the groups (p≤0.0001).Conclusion: Thus, this study concludes that both aerobic exercises and resistance training prove to be beneficial in controlling blood glucose levels in T2DM subjects.

scholarly journals Effectiveness of Coriander Seed Extract in decreasing Blood Glucose level among Diabetic Patients

2020 ◽  
Vol 11 (3) ◽  
pp. 2879-2883
Author(s):  
Sheela R ◽  
Merlin Shiny Sheeba ◽  
Poornima ◽  
Priya
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Low Income ◽  
Seed Extract ◽  
Medical Expenditure ◽  
Diabetic Patients ◽  
Treatment Of Diabetes ◽  
Coriander Seed

Diabetes Mellitus (DM) belongs to a group of metabolic disorders. It is characterised by Chronic Hyperglycemia and disturbance of carbohydrate, lipid and protein metabolism. The cause for this condition arises from a disease in insulin secretion. The International Diabetes Federation (IDF) expresses that worldwide 415 million individuals have Diabetes Mellitus. It also predicts that by 2040 this will ascend to 642 billion. The other prediction is that 77% of individuals with Diabetes live in middle and low-income countries. 12% of the worldwide population spend on the treatment of Diabetes. With the escalating medical expenditure in treating Diabetes, a person from middle or low income may find it challenging to meet the expenses. It is an expected tendency for an individual from this category to opt for a more straightforward treatment that suits their pocket. In the recent past, all over the world, people from all walks of life know essential things about natural remedies. A lot of researches are going on in support of using natural products per se. One such study is this – on the Effectiveness of Coriander Seed Extract in decreasing Blood Glucose level among Diabetic Patients.Coriandrum Sativum is a plant that has been utilised in the administration of Diabetes. It is a herbaceous plant originally from the Mediterranean and Middle Eastern locales, having a place in the family Apiaceae. It is known to have antifungal, antibacterial, free radical searching, and lipid peroxidation activities. The study was conducted to assess the level of pretest and posttest blood glucose level. And, also to evaluate the effect of coriander seed extract in the treatment of Diabetes Mellitus. An experimental study was chosen to assess the effectiveness of coriander seed extract among diabetic clients. The present study was conducted at Mappedu. 60 male and female who come under inclusion criteria were selected by purposive sampling technique. Data was collected by using a socio-demographic variable, and random blood glucose was assessed by CBG machine. The results revealed that coriander seed extract has a significant effect on decreasing blood glucose level among diabetic patients.

scholarly journals Biochemical markers in saliva of patients with diabetes mellitus

2012 ◽  
Vol 59 (4) ◽  
pp. 198-204 ◽  
Author(s):  
Biljana Andjelski-Radicevic ◽  
Radica Dozic ◽  
Tatjana Todorovic ◽  
Ivan Dozic
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Diabetic Patients ◽  
Non Invasive ◽  
Stress Markers ◽  
Frequent Monitoring ◽  
Patients With Diabetes ◽  
Protein Components

Diabetes mellitus is metabolic syndrome characterized by disorder in metabolism of carbon hydrates, lipids and proteins. The diagnosis of diabetes is established by measuring the blood glucose level using standardized methods. Frequent monitoring of blood glucose level could be inconvenient for patients because of possible pain during blood sample taking. In the last few years biological materials with non invasive sampling, like saliva, have been analyzed. Research has confirmed that some organic and inorganic components of saliva are modified in diabetic patients (glucose, lipid and protein components, oxidative stress markers, electrolytes). Beside other markers, the analysis of glucose in saliva is an attempt to find a non-invasive and painless way for frequent monitoring of glucose concentration in diabetic patients. Collecting saliva is simple and economical, it neither requires expensive equipment nor specially trained staff. Saliva can be taken many times and in unlimited quantity. In regards to the data about the possibilities for using saliva as biological sample in monitoring diabetes mellitus, which could be alternative to blood serum or plasma, the conclusion is that saliva becomes more important in this context.

Controlling Hyperglycaemia Diabetes Mellitus Type-II: Bromocriptine Alone or in Combination with Metformin

2021 ◽  
Vol 15 (12) ◽  
pp. 3348-3350
Author(s):  
Khadija Mastoor ◽  
Faisal Idrees Khan ◽  
Iram Imran ◽  
Anila Errum ◽  
Sadia Sharif ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Body Weight ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Pancreatic Beta Cells ◽  
Male Rats ◽  
Diabetic Patients ◽  
Group 2 ◽  
Therapeutic Doses

Background: Diabetes Mellitus is one of the leading cause of morbidity and mortality globally. According to WHO there is a steady increase in the number of diabetic patients annually. Maintenance of good glycaemic control in type 2 diabetic patients typically becomes progressively more difficult as the duration of disease lengthens due to decline in the capacity of the pancreatic beta cells for glucose stimulated insulin release, in the presence of insulin resistance. This study is conducted to observe the effect of metformin and bromocriptine individually and sub-therapeutic doses of these drugs when used as a combination therapy. Objective: The objective of this study is to primarily investigate and then compare the antihyperglycemic effects of bromocriptine with metformin, also to see the combined effect of sub therapeutic doses of both these drugs. Methodology: Random allotment of 24 albino male rats was done in four groups. Group 1 was kept as control. Alloxan monohydrate was given to group 2, 3 and 4 and diabetes was induced. Group 2 and 3 were treated with metformin (1.5mg/kg body weight) and bromocriptine (3 mg/kg body weight) respectively while group 4 was treated with sub therapeutic doses of metformin (1 mg/kg body weight) and bromocriptine (1.5 mg/kg body weight)both. Serum glucose levels were estimated at 1, 10, 20 and 30 days. Results: Results showed that metformin reduces blood glucose level significantly where as bromocriptine also showed reduction of blood glucose level but not as significantly as metformin. However, the combination of metformin and bromocriptine showed much reduction in blood glucose level than metformin and bromocriptine used alone. Conclusion: Bromocriptine and metformin when combined ameliorated blood guclose efficiently than given alone Keywords: Diabetes mellitus, bromocriptine, metformin

TO STUDY THE RELATIONSHIP BETWEEN THE GLYCOSYLATED HAIR PROTEIN AND HBA1C FOR ASSESSMENT OF BLOOD GLUCOSE LEVEL IN DIABETES MELLITUS TYPE II

1969 ◽  
Vol 3 (2) ◽  
pp. 346-349
Author(s):  
HARESH KUMAR ◽  
MONA RANI ◽  
MOHAMMAD HANIF ◽  
KHEMOMAL A. KARIRA ◽  
MOHAMMAD MUNIB ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Enzymatic Reaction ◽  
Diabetes Mellitus Type ◽  
Diabetic Patients ◽  
Type Ii ◽  
Hair Root ◽  
Diabetes Mellitus Type Ii

BACKGROUND: Hair is a dead tissue and is composed of keratin and related proteins. Hair is a protein offew growing cells at the base of the hair root. If the patient is diabetic glycosylation occurs in these growingcells.Since the extent of glycation of hair protein varies with the distance from the hair root, we hypothesizedthat glycation of hair protein might provide insight into blood glucose level over a period of several mouthsto one year.So hemoglobin Ale (HbAIc) may be established as an indicator of long-term blood glucosecontrol in diabetic patients. It is formed by non-enzymatic reaction of glucose with Hb.The objective of thisstudy was to estimate the furosine(an intermediate in the breaking down of amadori compounds likeglycosylated proteins) level by HPLC of glycosylated hair proteins, to find interrelation of fasting glucosewith HbAIc and furosine in diabetic patients, to determine the efficacy of Glycosylation of HbA,c andfurosinemay be a reliable marker in diabetic patients.STUDY DESIGN: This study was carried out in the department of Biochemistry Basic Medical SciencesInstitute (BMSI) Jinnah Postgraduate Medical Centre Karachi.METHODS: A total of 200 subjects were included in the study. 100 diagnosed type II and 100 controlnormal subjects. Hair from the scalp 12 cm long and 50 mg in weight was collected from each subject tomeasure furosine level. Furosine level was determined by HPLC and HbAIc, FBSand serumprotein byenzymatic kit method.RESULTS: When the mean values were compared with that of control it depicted significantly high level(0.001) of furosine, HbAIc and FBS.CONCLUSION: The furosine, HbAIc and FBS levels increases in diabetic patients while total serumprotein were unaffected. Weight and BMI increases in diabetic but height was unaffected.KEYWORDS: Diabetes mellitus type II, furosine, HbAIc, fasting blood sugar, glycation ofhair protein

scholarly journals Gambaran Karies Gigi pada Penyandang Diabetes Melitus di Rumah Sakit Kalooran Amurang

e-GIGI ◽  
2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Falen V. Ampow ◽  
Damajanty H. C. Pangemanan ◽  
Pritartha S. Anindita
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Dental Caries ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Glucose Control ◽  
Blood Glucose Control ◽  
Diabetic Patients ◽  
Very High ◽  
Diabetes Melitus

Abstract: Dental caries is caused by certain bacteria that have acid-forming properties. Due to these bacteria, a low pH in the oral cavity is achieved which may cause slow enamel demineralization and form a ferocious focus. Diabetes mellitus (DM), a metabolic disorder characterized by hyperglycemia, is one of the predisposing factors of dental caries. This study was aimed to obtain the profile of dental caries in people with diabetes mellitus. This was a descriptive study with a cross sectional design. Subjects were diabetic patients at the Internal Medicine Department of Kalooran Hospital Amurang. There were 50 patients in this study obtained by using total sampling technique. Diabetic status was determined by using random blood glucose level (Perkeni 2011) meanwhile caries status was assessed by using DMF-T score. Data were processed by using SPSS and then were presented in tabular form. The results showed that very high caries index was found in 16.0% of subjects with good blood glucose control, 30.0% with moderate blood glucose control, and 36.0% with poor blood glucose control; the total number was 82.0% of subjects. Most subjects had diabetes for 5-10 years (44.0%) with very high caries index (40.0%). Conclusion: Most diabetic patients had very high caries index with the highest percentage in patients with DM for 5-10 years and in patients with poor blood glucose control.Keywords: diabetes mellitus, blood glucose level, dental caries Abstrak: Karies gigi terjadi oleh karena bakteri-bakteri tertentu yang mempunyai sifat membentuk asam sehingga terjadi pH rendah yang dapat menyebabkan pelarutan mineral enamel secara perlahan dan membentuk fokus perlubangan. Diabetes melitus (DM) yang ditandai dengan keadaan hiperglikemia merupakan salah satu faktor predisposisi terjadinya karies. Penelitian ini bertujuan untuk mengetahui gambaran karies gigi pada penyandang DM. Jenis penelitian ialah deskriptif dengan desain potong lintang. Subjek penelitian ialah penyandang DM di Poliklinik Penyakit Dalam RS Kalooran Amurang yang berjumlah 50 orang, diambil dengan teknik total sampling. Status DM dinilai melalui kadar glukosa darah sewaktu (Perkeni 2011), sedangkan status karies dinilai menggunakan skor DMF-T. Data diolah menggunakan SPSS kemudian disajikan dalam bentuk tabel. Hasil penelitian menda-patkan kategori indeks karies sangat tinggi ditemukan pada 16,0% subyek dengan kontrol gula darah baik, 30,0% dengan kontrol gula darah sedang, dan 36,0% dengan kontrol gula darah buruk; jumlah total 82,0% subyek. Subjek terbanyak ialah penyandang DM 5-10 tahun (44,0%) dengan kategori indeks karies sangat tinggi (40,0%). Simpulan: Sebagian besar penyandang DM memiliki kategori indeks karies sangat tinggi dengan persentase tertinggi pada penyandang DM 5-10 tahun dan penyandang DM dengan kontrol gula darah yang buruk.Kata kunci: diabetes melitus, kadar gula darah, karies gigi

scholarly journals Effect of Local Anesthesia with 1:100,000 Epinephrine on Glycemic Level of Type II Diabetic Patients Undergoing Oral Surgery

1969 ◽  
Vol 11 (4) ◽  
pp. 181-184
Author(s):  
Muhammad Tariq Khan ◽  
Muhammad Ilyas ◽  
Salman Khan ◽  
Jawad Ahmad Kundi ◽  
Fariha Kifayat
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Local Anesthesia ◽  
Glucose Level ◽  
Oral Surgery ◽  
Diabetic Patients ◽  
Type Ii ◽  
Glycemic Level ◽  
Significant Difference

Background: The rate of type II diabetic patients is increasing and results in oral manifestations. The oral surgery needsextraordinary measures in these patients.Objective: To assess the effect of anesthetic agent with 1:100,000 epinephrine and without epinephrine in the blood glucose levelof diabetic patients.Material and Methods: This was a randomized study of 60 patients having type 2 diabetes mellitus who were undergoing toothextraction. The study was double blind. 30-70years aged patients were selected. Blood glucose level was monitored 15 minutesbefore giving local anesthesia and after 20 minutes of the injection. ANOVA was used for comparison between groups.Results: No significant difference was seen in glycemic level using local anesthesia with 1:100,000 epinephrine (p=0.345). Therewas slight decrease noted in the blood glucose level of both groups.Conclusion: The use of 2% local anesthesia with 1:100,000epinephrine didn't cause hyperglycemia in diabetic patients.Keywords: Diabetes Mellitus, Local Anesthesia, Epinephrine, Tooth Extraction, Lidocaine.

scholarly journals TO STUDY THE EFFECT OF YOGA ON BLOOD SUGAR PROFILE IN DIABETICS TYPE-2 PATIENTS

2019 ◽  
Vol 3 (7) ◽  
Author(s):  
Dr. B S Gupta ◽  
Dr. Yogesh Singh
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Mean Value ◽  
T Test ◽  
Diabetic Patients ◽  
The Mean ◽  
The Difference

Background: Diabetes mellitus is a syndrome complex characterized by impaired carbohydrate, protein and fat metabolism. Methods: Prospective study was conducted on 100 type 2 diabetes mellitus patients and 100 normal healthy persons. Cases were recruited from a yoga centre. Control subjects were selected from diabetic patients attending hospital. Alcoholic or smoker subjects were excluded. Results: The mean value of blood glucose level of subjects was 136.4±9.42 mg/dl and that of controls was 183.2±9.16 mg/dl.  The difference between the mean value of fasting blood glucose level determined by unpaired  ‘t’ test was statistically highly significant (p=<0001). The mean value of blood glucose level of subjects was 6.32±1.35 % and that of controls was 7.46±1.41%.  The difference between the mean value of HB1Ac level determined by unpaired  ‘t’ test was statistically highly significant (p=<0001). Conclusion: Yoga can be used as an alternate therapy to reduce the blood glucose level along with the drug therapy. Keywords: Yoga, Diabetics, Drugs.

Assessment of the antidiabetic potential of Gymnemic acid as α-amylase and α-Glucosidase inhibitor using invitro and insilico tools

2021 ◽  
pp. 4755-4759
Author(s):  
Porkodi Karthikeyan ◽  
M.V. Dass Prakash ◽  
Pavithra Devi Sendurapandi ◽  
Kalaiselvi Periandavan
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Cost Effective ◽  
Docking Study ◽  
Postprandial Blood Glucose ◽  
Gymnemic Acid ◽  
Glucose Levels ◽  
Ic50 Value

Diabetes Mellitus is a metabolic disorder characterized by elevated blood glucose level caused due to deficiency of insulin secretion or insulin action. The management of the blood glucose level is an important approach in the control of diabetes mellitus complications. There are many divergent therapeutic strategies in the management of Type II diabetes. The inhibition of carbohydrate hydrolyzing enzymes such as α-amylase and α-glucosidase can be used to lower postprandial blood glucose levels. The objective of the present study is to evaluate the inhibitory potential of Gymnemic acid in various concentrations on α-amylase and α-glucosidase activities. Gymnemic acid and voglibose show the IC50 value of 68.12 and 46.23 on alpha amylase and IC50 value of 65.77 and 36.67 on alpha glucosidase activity respectively. Insilico docking study between α-amylase and α-glucosidase with gymnemic acid and voglibose depict the similar amino acid binding sites that substantiate that gymnemic acid might be used as a natural and cost-effective alternative to the synthetic drug. This study throws light on the anti-diabetic action of phytomedicine, Gymnemic acid, a component of Gymnema sylvestre.

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