scholarly journals The relationship of active ghrelin levels and intrauterine growth in preterm infants

2012 ◽  
Vol 166 (3) ◽  
pp. 399-405 ◽  
Author(s):  
Hamilcikan Sahin ◽  
Tugba Erener ◽  
Ethem Erginoz ◽  
Mehmet Vural ◽  
Barbaros Ilikkan ◽  
...  
Keyword(s):  
Birth Weight ◽  
Preterm Infants ◽  
Negative Correlation ◽  
Gestational Age ◽  
Elisa Method ◽  
Intrauterine Growth ◽  
Relationship Of ◽  
The Relationship

ObjectiveWe examined the association of active ghrelin levels with birth weight, sex, and gestational age (GA) in small for GA (SGA) and appropriate for GA (AGA) preterm infants.MethodsActive ghrelin levels were measured by ELISA method during the first five postnatal days in 38 preterm SGA infants and 32 preterm AGA controls.ResultsActive ghrelin levels were significantly higher in preterm SGA infants than in preterm AGA controls (P<0.01). Active ghrelin levels in preterms with birth weight <1500 g were statistically higher than those over 1500 g. Active ghrelin levels in preterms ≤34 gestational weeks were similar to those over 34 weeks. A negative correlation was detected between active ghrelin levels and birth weight (r=−0.561, P<0.0001) as well as GA (r=−0.449, P<0.0001).ConclusionWe found significantly higher active ghrelin levels in SGA preterms than those in AGA preterms and demonstrated a negative correlation between active ghrelin levels and birth weight in preterm infants. This was the first study showing a negative correlation between active ghrelin levels and birth weight in preterm infants.

scholarly journals Low birth weight, preterm birth and small for gestational age association with adult depression: systematic review and meta-analysis

2014 ◽  
Vol 205 (5) ◽  
pp. 340-347 ◽  
Author(s):  
Christian Loret De Mola ◽  
Giovanny Vinícius Araújo De França ◽  
Luciana de Avila Quevedo ◽  
Bernardo Lessa Horta
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Premature Birth ◽  
Fixed Effects ◽  
Meta Analysis ◽  
Adult Depression ◽  
Meta Analyses ◽  
Relationship Of ◽  
The Relationship

BackgroundThere is no consensus on the effects that low birth weight, premature birth and intrauterine growth have on later depression.AimsTo review systematically the evidence on the relationship of low birth weight, smallness for gestational age (SGA) and premature birth with adult depression.MethodWe searched the literature for original studies assessing the effect of low birth weight, premature birth and SGA on adult depression. Separate meta-analyses were carried out for each exposure using random and fixed effects models. We evaluated the contribution of methodological covariates to heterogeneity using meta-regression.ResultsWe identified 14 studies evaluating low birth weight, 9 premature birth and 4 SGA. Low birth weight increased the odds of depression (OR = 1.39, 95% CI 1.21–1.60). Premature birth and SGA were not associated with depression, but publication bias might have underestimated the effect of the former and only four studies evaluated SGA.ConclusionsLow birth weight was associated with depression. Future studies evaluating premature birth and SGA are needed.

THE RELATIONSHIP OF PLACENTAL THICKNESS WITHGESTATIONALAGE IN THIRD TRIMESTER AND PROBABLE FETAL OUTCOME

2021 ◽  
pp. 64-66
Author(s):  
Sambhunath Bandyopadhyay ◽  
Ritayan Sasmal ◽  
Debarshi Jana
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Age Determination ◽  
Fetal Outcome ◽  
Inclusion Criteria ◽  
Third Trimester ◽  
Relationship Of ◽  
The Relationship ◽  
Placental Thickness

Accurate gestational age determination is very important for management of continuation and termination planning of the pregnancy. rd To establish placental thickness as a parameter for determination of gestational age and fetal growth pattern at 3 trimester. 100 primigravida women who are fullling the inclusion criteria and attend gynae &obs OPD or admitted in their third trimester at IPGME&R from January 2017 to june 2018. Placental thickness at 3rd trimester USG scan is moderately correlated with gestational age, if placental thickness expressed in millimeter then it correlated with gestational age at weeks. rd st Placental thickness with >3.2 cm (32 mm) at 3 trimester almost associated with good fetal outcome, with APGAR score >8 at 1 min and birth weight >2500 gm.

scholarly journals Kisspeptin: new biomarker of pregnancy

2019 ◽  
Vol 8 (8) ◽  
pp. 3021
Author(s):  
Priyanka Meena ◽  
Rati Mathur ◽  
Mohan L. Meena
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Positive Relationship ◽  
Elisa Method ◽  
Medical College ◽  
Obstetrics And Gynaecology ◽  
Study Participants ◽  
Relationship Of ◽  
The Relationship ◽  
Single Blood Sample

Background: The recently identified hormone kisspeptin has been suggested to play an important regulatory role in placentation. The aim and objective of the study is the measurement of serum kisspeptin level in asymptomatic pregnant women and to find out the association of serum kisspeptin with gestational age in women with early pregnancy.Methods: This was a longitudinal study to the evaluation of 178 asymptomatic pregnant women with a gestation of 6 to 16 weeks attending routine antenatal booking visit recruited as study participants from the Antenatal Clinical of Obstetrics and Gynaecology Department, S.M.S. Medical College and Attached Hospitals, Jaipur, Rajasthan, India.Results: After initial clinical examination of every participant, a single blood sample was taken for the measurement of serum kisspeptin. Serum kisspeptin measurement test was performed by ELISA method and results were expressed as ng/ml. Pregnancy outcome was recorded prospectively. Mean serum kisspeptin level of study participants was 2.80±1.87ng/ml and median were 2.41 (Range 0.244-14.06ng/ml). Our result showed the relationship of serum kisspeptin with gestational age (GA) (p<0.000).Conclusions: serum kisspeptin level increases in pregnancy and showed positive relationship with gestational age significantly (p<0.000).

Epidemiology of Inguinal Hernia in Preterm Neonates

PEDIATRICS ◽  
1986 ◽  
Vol 77 (2) ◽  
pp. 246-247 ◽  
Author(s):  
KEITH J. PEEVY ◽  
FELICITY A. SPEED ◽  
CHARLES J. HOFF
Keyword(s):  
Inguinal Hernia ◽  
Birth Weight ◽  
Preterm Infants ◽  
Gestational Age ◽  
Growth Retardation ◽  
Intrauterine Growth Retardation ◽  
Preterm Neonates ◽  
Intrauterine Growth ◽  
Inguinal Hernias

We have studied the epidemiology of inguinal hernias in preterm infants. Inguinal hernias occur with increased frequency in infants ≤32 weeks' gestational age or ≤1,250 g birth weight. Among infants ≤32 weeks' gestational age, intrauterine growth retardation significantly increases the risk for development of inguinal hernias, especially in male infants. Our data demonstrate a previously unrecognized association between neonatal inguinal hernia and intrauterine growth retardation.

The Relationship of Early Behaviour to Later Developmental Outcome for Preterm Children

1996 ◽  
Vol 19 (3) ◽  
pp. 517-532 ◽  
Author(s):  
Jaroslava Dittrichová ◽  
Václav Břicháček ◽  
František Mandys ◽  
Karel Paul ◽  
Daniela Sobotková ◽  
...  
Keyword(s):  
Social Environment ◽  
Preterm Infants ◽  
Gestational Age ◽  
Early Identification ◽  
Developmental Outcomes ◽  
First Year ◽  
The Social ◽  
First Year Of Life ◽  
Relationship Of ◽  
The Relationship

The present study aimed, first, to analyse in detail early sleep states in 21 preterm infants born before the 33rd week of gestational age and compare them with sleep states in 23 fullterm infants assessed at gestationally matched ages in the first six months. Second, to determine whether analyses of early sleep states in preterm infants may enable identification of infants with future developmental disabilities. In addition to evaluations of perinatal risk factors, neurological condition, psychological development, and social environment during the first year of life, examinations of psychological and neurological development and the assessment of the social environment at 3 and 9 years were carried out. Measures of perinatal status and sleep states up to the age of 40 weeks gestational age did not correlate with outcome measures at 3 and 9 years. However, the polygraphic measures of sleep states at 12 and 24 weeks corrected age, predicted the 3-year developmental outcomes. The complexity of these measures may contribute to their predictive validity for the outcomes at 3 years. Measures of the social environment at 3 and 9 years contributed significantly to the prediction of 9-year developmental outcomes. These results indicate that environmental factors may become more important with age. The detailed analysis of early sleep patterns may enable the early identification of infants who need special care and intervention.

scholarly journals The Correlation Between Bronchopulmonary Dysplasia and Platelet Metabolism in Preterm Infants

2021 ◽  
Vol 9 ◽  
Author(s):  
Longli Yan ◽  
Zhuxiao Ren ◽  
Jianlan Wang ◽  
Xin Xia ◽  
Liling Yang ◽  
...  
Keyword(s):  
Platelet Count ◽  
Birth Weight ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Premature Infants ◽  
Gestational Age ◽  
Admission Diagnosis ◽  
Control Group ◽  
The Relationship

Background: Platelets play an important role in the formation of pulmonary blood vessels, and thrombocytopenia is common in patients with pulmonary diseases. However, a few studies have reported on the role of platelets in bronchopulmonary dysplasia.Objective: The objective of the study was to explore the relationship between platelet metabolism and bronchopulmonary dysplasia in premature infants.Methods: A prospective case-control study was performed in a cohort of premature infants (born with a gestational age &lt;32 weeks and a birth weight &lt;1,500 g) from June 1, 2017 to June 1, 2018. Subjects were stratified into two groups according to the diagnostic of bronchopulmonary dysplasia: with bronchopulmonary dysplasia (BPD group) and without bronchopulmonary dysplasia (control group). Platelet count, circulating megakaryocyte count (MK), platelet-activating markers (CD62P and CD63), and thrombopoietin (TPO) were recorded and compared in two groups 28 days after birth; then serial thrombopoietin levels and concomitant platelet counts were measured in infants with BPD.Results: A total of 252 premature infants were included in this study. Forty-eight premature infants developed BPD, 48 premature infants without BPD in the control group who were matched against the study infants for gestational age, birth weight, and admission diagnosis at the age of postnatal day 28. Compared with the controls, infants with BPD had significantly lower peripheral platelet count [BPD vs. controls: 180.3 (24.2) × 109/L vs. 345.6 (28.5) × 109/L, p = 0.001]. Circulating MK count in the BPD group was significantly more abundant than that in the control group [BPD vs. controls: 30.7 (4.5)/ml vs. 13.3 (2.6)/ml, p = 0.025]. The level of CD62p, CD63, and TPO in BPD group was significantly higher than the control group [29.7 (3.1%) vs. 14.5 (2.5%), 15.4 (2.0%) vs. 5.8 (1.7%), 301.4 (25.9) pg/ml vs. 120.4 (14.2) pg/ml, all p &lt; 0.05]. Furthermore, the concentration of TPO was negatively correlated with platelet count in BPD group with thrombocytopenia.Conclusions: Our findings suggest that platelet metabolism is involved in the development of BPD in preterm infants. The possible mechanism might be through increased platelet activation and promoted TPO production by feedback.

scholarly journals Development of Symphysio Fundal Height Curve

2017 ◽  
Vol 32 (1) ◽  
pp. 20-24
Author(s):  
Chowdhury Taslima Nasrein ◽  
Ferdousi Begum ◽  
Jaglul Haider Khan ◽  
Novera Islam ◽  
Zahangir Alam
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Gestational Age ◽  
Cross Sectional ◽  
Medical College ◽  
Gestation Age ◽  
The Mean ◽  
Relationship Of ◽  
The Relationship

Objective: To Develop a symphysio fundal height(SFH) curve of pregnant women from 20 weeks of pregnancy onwards; and to find out the relationship of fundal height with different variables. Methodology: A cross-sectional hospital based study was conducted from 1st january 2010 to 31st December 2010 on 159 patients with gestation age less than 20 weeks at entry in the OPD of Department of Obstetric and Gynaecology, Shaheed Suhrawardy Medical College & Hospital, Shere-e Bangla Nagar, Dhaka,Bangladesh. All the patients were followed up till delivery. Results: The measurements of SFH obtained on the basis of 10, 50th and 90th percentiles and the rate of growth of SFH was approximately 5 mm per week from 24 weeks to 36 weeks and thereafter it was 5-6 mm per week till 40 weeks.Patients with higher socioeconomic class had higher symphysio fundal height.SFH is less in younger subjects. SFH increases with increased height,weight,gestational age,gravidity of mothers and birth weight of the baby.Multiparous was predominant and more than one third (34.6%) of the study patients height belonged to 1.51 - 1.60 meters. The mean±SD gestational age was 39.2±1.4 weeks with range from 28 to 41 weeks. Low birth weight was found 17.0% and the mean±SD birth weight was 2.8±0.4 kg with range from 1.9 to 3.8 kg. Bangladesh J Obstet Gynaecol, 2017; Vol. 32(1): 20-24

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