scholarly journals Changes in serum inhibin B during normal male puberty

2005 ◽  
Vol 152 (3) ◽  
pp. 403-409 ◽  
Author(s):  
A F Radicioni ◽  
A Anzuini ◽  
E De Marco ◽  
I Nofroni ◽  
V D Castracane ◽  
...  

Objective: In adult men, inhibin B (InhB) regulates FSH secretion by a negative feedback. The aims of this study were to evaluate the changes of InhB during puberty in the male and the relationship between InhB and FSH, LH, testosterone and testicular volume. Design: Cross-sectional study. Methods: InhB was measured using a two-site ELISA in 100 healthy boys subdivided by their pubertal development according to Tanner into five groups of 20. Results: During puberty we observed an increase of InhB level (G1 = 84.3 pg/ml, G3 = 132.2 pg/ml, G5 = 206.1 pg/ml). In G1, InhB correlated positively with FSH (P = 0.0001), LH (P = 0.005), testosterone (P = 0.001) and testicular volume (P = 0.007); in G5, InhB correlated inversely with FSH (P = 0.001) and LH (P = 0.045) and directly with testicular volume (P = 0.013). The multivariate analysis demonstrated that: in G1, FSH is the most important, and testosterone the second most significant, stimulus for InhB increase; in G2 only FSH has a positive effect on InhB variation; in G3 only mean testicular volume fits the model (G1–G3: InhB dependent variable); considering the FSH dependent variable, in G4, InhB is the most important stimulus for FSH decrease and mean testicular volume is a secondary directly proportional variable; in G5, only InhB shows a significant inverse relationship with FSH. Conclusions: During puberty there is a regular increase of InhB. In the first phases of gonadal maturation, InhB and FSH correlate positively, while in mid–late stages the relationship is inverse. We found that in mid-puberty (G3–G4), the serum concentration of InhB increases, as its inverse relationship with FSH is being established and hence spermatogenesis.

1989 ◽  
Vol 121 (2) ◽  
pp. 383-387 ◽  
Author(s):  
J. M. P. Holly ◽  
C. P. Smith ◽  
D. B. Dunger ◽  
J. A. Edge ◽  
R. A. Biddlecombe ◽  
...  

ABSTRACT We have looked at the relationship between fasting levels of insulin and a small insulin-like growth factor (IGF)-binding protein (IBP-1) in a cross-sectional study of 116 normal subjects aged 5–48 years. The relationship between IBP-1 and insulin was also examined within individual normal children in over-night profiles of IBP-1 and insulin obtained from two children at each stage of puberty (Tanner stages 1–5). In the cross-sectional study high levels of IBP-1 were found in early childhood and these fell throughout puberty as fasting levels of insulin rose. Multiple regression analysis revealed that both these changes were predominantly due to pubertal development rather than to age. After the age of 16 IBP-1 levels remained low despite fasting insulin levels returning to prepubertal levels. A strong negative correlation was obtained between IBP-1 and insulin in children of 5–16 years (r = −0·63; n = 60; P <0·001), no such relationship being found after the age of 16. In the second study, IBP-1 underwent a marked circadian variation in all cases and an inverse correlation with insulin, measured at the same time, was obtained at pubertal stages 1 to 4, but not at stage 5 (pooled data stages 1–4, r = −0·69; n = 53; P <0·001). We have demonstrated that a potential inhibitor of IGF-activity is inversely related to insulin throughout the period of active GH-related growth and that this relationship weakens after puberty. Journal of Endocrinology (1989) 121, 383–387


2016 ◽  
Vol 2016 ◽  
pp. 1-12 ◽  
Author(s):  
Rebecca A. Seguin ◽  
Anju Aggarwal ◽  
Francoise Vermeylen ◽  
Adam Drewnowski

Introduction. Consumption of foods prepared away from home (FAFH) has grown steadily since the 1970s. We examined the relationship between FAFH and body mass index (BMI) and fruit and vegetable (FV) consumption.Methods. Frequency of FAFH, daily FV intake, height and weight, and sociodemographic data were collected using a telephone survey in 2008-2009. Participants included a representative sample of 2,001 adult men and women (mean age54±15years) residing in King County, WA, with an analytical sample of 1,570. Frequency of FAFH was categorized as 0-1, 2–4, or 5+ times per week. BMI was calculated from self-reported height and weight. We examined the relationship between FAFH with FV consumption and BMI using multivariate models.Results. Higher frequency of FAFH was associated with higher BMI, after adjusting for age, income, education, race, smoking, marital status, and physical activity (women:p=0.001; men:p=0.003). There was a negative association between frequency of FAFH and FV consumption. FAFH frequency was significantly (p<0.001) higher among males than females (43.1% versus 54.0% eating out 0-1 meal per week, resp.). Females reported eating significantly (p<0.001) more FV than males.Conclusion. Among adults, higher frequency of FAFH was related to higher BMI and less FV consumption.


2020 ◽  
Vol 12 (3) ◽  
pp. 76-80
Author(s):  
Azam valian ◽  
Zahra Jaberi-Ansari ◽  
Arash Delshad ◽  
Mohammad Reza Hosseini Kordkheili

Background: The prevalence and severity of tooth decay have shown a significant increase in the past 20 years. This study evaluated the relationship between the amount of tooth decay and body mass index (BMI) in 6-12 year-old children in Ilam during 2016-2017. Methods: The population of this cross-sectional study consisted of 270 female and 250 male students in Ilam. Their weight and height and BMI were measured for each individual and the information on the examination of children’s teeth was inserted into relevant tables. Other research data (i.e., dietary habits, oral health instruction, and socioeconomic conditions) were gathered using a valid and reliable questionnaire. Results: There was no significant relationship between the amount of tooth decay and BMI among 6-12 children in Liam. Except for the 11-year-old (n=86) group demonstrating an inverse relationship between dmft and BMI (r = -0.185), an inverse relationship was found between the decay and observation of health although there was a direct relationship between the consumption of sugar materials and tooth decay. Conclusions: The results of the study revealed no significant relationship between the amount of tooth decay and BMI among 6-12 children in Ilam except for 9-year-old and 11-year-old groups.


2007 ◽  
Vol 19 (4) ◽  
pp. 472-480 ◽  
Author(s):  
Ailsa G. Niven ◽  
Samantha G. Fawkner ◽  
Ann-Marie Knowles ◽  
Claire Stephenson

This cross-sectional study examined the relationship between physical self-perceptions (PSPs), maturation, and physical activity and compared the strength of the relationships of biological and chronological age with PSPs in early adolescent girls (N = 208; mean age = 11.83 ± 0.39 years). Participants completed the Physical Activity Questionnaire for Older Children, the Children’s Physical Self-Perception Profile, and the Pubertal Development Scale. Results indicated that PSPs were significantly and moderately correlated with physical activity. There were no differences in physical activity between maturation stages. Girls who were in the early stages of maturation had significantly more positive perceptions of body attractiveness and physical self-worth than girls in the mid stages of maturation. There was no evidence of a relationship between PSPs and chronological age. This study provided further support for the relationship between PSPs and physical activity and the relationship between maturation and aspects of PSPs. In this age group, maturation does not appear to be related to physical activity or the PSPs most strongly influential on physical activity behavior.


Crisis ◽  
2011 ◽  
Vol 32 (5) ◽  
pp. 272-279 ◽  
Author(s):  
Allison S. Christian ◽  
Kristen M. McCabe

Background: Deliberate self-harm (DSH) occurs with high frequency among clinical and nonclinical youth populations. Although depression has been consistently linked with the behavior, not all depressed individuals engage in DSH. Aims: The current study examined maladaptive coping strategies (i.e., self-blame, distancing, and self-isolation) as mediators between depression and DSH among undergraduate students. Methods: 202 students from undergraduate psychology courses at a private university in Southern California (77.7% women) completed anonymous self-report measures. Results: A hierarchical regression model found no differences in DSH history across demographic variables. Among coping variables, self-isolation alone was significantly related to DSH. A full meditational model was supported: Depressive symptoms were significantly related to DSH, but adding self-isolation to the model rendered the relationship nonsignificant. Limitations: The cross-sectional study design prevents determination of whether a casual relation exists between self-isolation and DSH, and obscures the direction of that relationship. Conclusions: Results suggest targeting self-isolation as a means of DSH prevention and intervention among nonclinical, youth populations.


2019 ◽  
Vol 7 (2) ◽  
pp. 115
Author(s):  
Dini Yuliansari

The well is one of the source water used for bathing, washing, and drinking by the citizens in Jiken Hamlet, Rarang Village, Terara Sub-District. Poor dug well construction conditions can affect the amount of coliform bacteria contained in the dug well water. The purpose of this study is to identify the construction of dug wells and the content of coliform bacteria in dug well water and determine the relationship between dug well construction and the content of coliform bacteria. This research is analytic with a cross sectional study design. The results were obtained from 11 samples of dug wells which were observed in construction and the coliform content was known that all samples did not requirements as good dug well construction. Coliform content test results showed that as many as 5 dug well water samples did not pass the clean water quality standards. The results of data analysis with the chi-square test variable construction of dug wells with coliform content variable  showed 0,172 > 0,05, then the concluded is the dug well not suitable to use by people in that area as a source of water for daily needs.


Sign in / Sign up

Export Citation Format

Share Document