scholarly journals Do Prenatal Exposures Pose a Real Threat to Ovarian Function? BPA as a Case Study

Reproduction ◽  
2019 ◽  
Author(s):  
Hannah Mathew ◽  
Shruthi Mahalingaiah

Fetal development represents a time of potential vulnerability due to rapid cell division, organ development, and limited fetal kidney/liver activity for detoxification and metabolism of exposures. Health effects of prenatal toxicant exposure have previously been described, but there is little cohesive evidence surrounding effects on ovarian function. Using bisphenol A (BPA) as a case study, we seek to examine whether a prominent prenatal environmental exposure can pose a real threat to human ovarian function. To do so, we broadly review human oogenesis and menstrual cycle biology. We then present available literature addressing prenatal bisphenol A and diverse outcomes at the level of the ovary. We highlight relevant human cohorts, and mammalian models to review the existing data on prenatal exposures and ovarian disruption. Doing so suggests that while current exposures to BPA have not shown marked or consistent results, there is data sufficient to raise concerns regarding ovarian function. Challenges in the examination of this question suggests the need for additional models and pathways by which to expand these examinations in humans.

2019 ◽  
Vol 19 (2) ◽  
pp. 101-110
Author(s):  
Adrian Firdaus ◽  
M. Dwi Yoga Sutanto ◽  
Rajin Sihombing ◽  
M. Weldy Hermawan

Abstract Every port in Indonesia must have a Port Master Plan that contains an integrated port development plan. This study discusses one important aspect in the preparation of the Port Master Plan, namely the projected movement of goods and passengers, which can be used as a reference in determining the need for facilities at each stage of port development. The case study was conducted at a port located in a district in Maluku Province and aims to evaluate the analysis of projected demand for goods and passengers occurring at the port. The projection method used is time series and econometric projection. The projection results are then compared with the existing data in 2018. The results of this study show that the econometric projection gives adequate results in predicting loading and unloading activities as well as the number of passenger arrival and departure in 2018. This is indicated by the difference in the percentage of projection results towards the existing data, which is smaller than 10%. Whereas for loading and unloading activities, time series projections with logarithmic trends give better results than econometric projections. Keywords: port, port master plan, port development, unloading activities  Abstrak Setiap pelabuhan di Indonesia harus memiliki sebuah Rencana Induk Pelabuhan yang memuat rencana pengem-bangan pelabuhan secara terpadu. Studi ini membahas salah satu aspek penting dalam penyusunan Rencana Induk Pelabuhan, yaitu proyeksi pergerakan barang dan penumpang, yang dapat dipakai sebagai acuan dalam penentuan kebutuhan fasilitas di setiap tahap pengembangan pelabuhan. Studi kasus dilakukan pada sebuah pelabuhan yang terletak di sebuah kabupaten di Provinsi Maluku dan bertujuan untuk melakukan evaluasi ter-hadap analisis proyeksi demand barang dan penumpang yang terjadi di pelabuhan tersebut. Metode proyeksi yang dipakai adalah proyeksi deret waktu dan ekonometrik. Hasil proyeksi selanjutnya dibandingkan dengan data eksisting tahun 2018. Hasil studi ini menunjukkan bahwa proyeksi ekonometrik memberikan hasil yang cukup baik dalam memprediksi aktivitas bongkar barang serta jumlah penumpang naik dan turun di tahun 2018. Hal ini diindikasikan dengan selisih persentase hasil proyeksi terhadap data eksisting yang lebih kecil dari 10%. Sedangkan untuk aktivitas muat barang, proyeksi deret waktu dengan tren logaritmik memberikan hasil yang lebih baik daripada proyeksi ekonometrik. Kata-kata kunci: pelabuhan, rencana induk pelabuhan, pengembangan pelauhan, aktivitas bongkar barang


2017 ◽  
Vol 15 (2) ◽  
pp. 145-169
Author(s):  
Roghayeh Farsi

AbstractThe academic field of Qurʾānic Studies employs a wide range of approaches, each one of which helps to open up a new perspective on the Qurʾānic text. The Holy Book was revealed to guide people; it is thus of relevance to all aspects of people’s lives. This article focuses on the way social actors are represented in one Meccansūra, entitled “Ya-Sin”, and employs a case-study approach to do so. The analysis carried out includes the socio-semantic processes that thesūrauses in order to represent social actors either by behavior (action) or meaning (reflection), and it also analyzes the actors as they are represented in processes such as activation and passivation. The methodology adopted is eclectic and analytic. It is a hybrid of Swales’ move analysis, El-Awa’s identification of shift-markers, and Halliday’s and Van Leeuwen’s theories of social actor representation. This study shows how such an analysis can contribute to understanding the apparently fragmented and non-linear nature of “Ya-Sin”.


2021 ◽  
Vol 13 (3) ◽  
pp. 1350
Author(s):  
Luz Elba Torres-Guevara ◽  
Vanessa Prieto-Sandoval ◽  
Andres Mejia-Villa

This paper contributes to the circular economy (CE) literature by investigating the drivers of success of the CE implementation in the construction sector and how those drivers can complement any implementation process in small and medium enterprises (SMEs). To do so, we analyzed the case of TECMO Estructuras Metálicas, using the methodology proposed by Jaca and colleagues to implement the CE in SMEs. It is a Colombian company with more than five decades of experience in the manufacture and installation of steel and aluminum structures for small and large building and infrastructure projects. The data were collected between August 2019 and November 2020 through direct communication with the company via workshops, meetings, and company reports. This research found that five drivers are relevant for implementing CE in the construction sector: fertile ecosystem, management commitment, identification of valuable materials, green teams, and CE intermediaries. Moreover, this study also contributes to teaching the implementation of the CE in companies, since it shows that through the methodology presented, implementation projects can be developed in postgraduate classes.


2016 ◽  
Vol 31 (8) ◽  
pp. 857-872 ◽  
Author(s):  
Paul Sissons ◽  
Katy Jones

This paper examines changes in local economic development policy which occurred between 2010 and 2015, with a focus on the relationship between industrial strategy and skills policy. Under the Coalition Government, Local Enterprise Partnerships were established and tasked with facilitating local growth, and to do so many identified a set of (potential) growth sectors for industrial strategy to support. These sectors tended to be drawn from a relatively narrow range of industries which therefore often excluded a large proportion of the local economy. An important focus of the support for growth sectors for many has been through an ambition to influence the local skills system. Skills policy more broadly has been an important dimension of devolution, and a number of City Deals have included elements of skills policy. Echoing previous national policy however, the focus of local concerns with skills under devolution has been framed largely with reference to skills gaps and shortages. While specific skills gaps and shortages can be identified, this paper questions whether this default position is reflected widely, and as such, if a narrow focus on skills supply is a sufficient approach. It is argued that to support local growth across a broad base, greater attention needs to be paid to stimulating employer demand for skills through better integrating industrial and innovation policy with skills policymaking across a wider section of the local economy. To support these arguments we present a case study of the Sheffield City Deal.


2011 ◽  
Vol 6 (2) ◽  
Author(s):  
Jon Carrick

This case examines the importance of customer service in the modern economy. In order to do so, it presents the findings from a case study on Avant Healthcare. In-depth interviews were conducted with two executives from the firm and then the interviews were systemically analyzed. The results give a clear example of how firms can build competitive advantages from customer service.


2020 ◽  
Vol 26 (1) ◽  
pp. 103-134 ◽  
Author(s):  
Huchang Liao ◽  
Hongrun Zhang ◽  
Cheng Zhang ◽  
Xingli Wu ◽  
Abbas Mardani ◽  
...  

As a generalized form of both intuitionistic fuzzy set and Pythagorean fuzzy sets, the q-rung orthopair fuzzy set (q-ROFS) has strong ability to handle uncertain or imprecision decisionmaking problems. This paper aims to introduce a new multiple criteria decision making method based on the original gain and lost dominance score (GLDS) method for investment evaluation. To do so, we first propose a new distance measure of q-rung orthopair fuzzy numbers (q-ROFNs), which takes into account the hesitancy degree of q-ROFNs. Subsequently, two methods are developed to determine the weights of DMs and criteria, respectively. Next, the original GLDS method is improved from the aspects of dominance flows and order scores of alternatives to address the multiple criteria decision making problems with q-ROFS information. Finally, a case study concerning the investment evaluation of the BE angle capital is given to illustrate the applicability and superiority of the proposed method.


2020 ◽  
Vol 23 ◽  
pp. 36-57
Author(s):  
Iker Fidalgo Alday

El presente artículo parte de un caso de estudio concreto que es la investigación en torno al archivo del colectivo artístico “Fundación Rodríguez” (Vitoria-Gasteiz, 1994-2012). El proceso de investigación estará marcado por todo lo que conlleva enfrentarse a un archivo compuesto por contenido digital y con formatos a punto de la obsolescencia, así como las dificultades para su conservación y mantenimiento. Partiendo de esto, se contextualizará la práctica de “Fundación Rodríguez” y el papel que juega el concepto de archivo en varias de las fases de su producción artística. Para ello analizaremos su posición desde el trabajo colectivo, la disolución del rol del artista y la desmaterialización de la obra artística como los tres frentes principales desde los que se erige su producción. Con todo, podremos valorar desde la actualidad la vigencia y relevancia de su legado, así como la potencia del mismo en el contexto artístico al que pertenece. This article starts from a concrete case study that is the research around the archive of the artistic collective “Fundación Rodríguez” (Vitoria-Gasteiz, 1994-2012). The research process will be marked by all that is involved in dealing with an archive composed of digital content and formats on the verge of obsolescence, as well as the difficulties of preserving and maintaining them. Starting from this, the practice of “Fundación Rodríguez” and the role played by the concept of archive in several of the phases of its artistic production will be contextualized. To do so, we will analyze its position from the perspective of collective work, the dissolution of the role of the artist and the dematerialization of the artistic work as the three main fronts from which its production is built.With all this, we will be able to evaluate from the present time the validity and relevance of his legacy as well as its power in the artistic context to which it belongs.


2020 ◽  
Vol 25 (3) ◽  
pp. 17
Author(s):  
Liliam Ramos ◽  
Jessica De Souza Pozzi

Resumo: Este artigo busca apresentar uma contribuição aos debates de culturas de língua francesa através de um estudo de caso sobre literatura antilhana por um viés decolonial (Walsh, 2013). Serão apresentados como exemplos decoloniais os estudos sobre a tradição dos contos crioulos, registrados e traduzidos para o francês por Ina Césaire e Joëlle Laurent em três obras bilíngues publicadas pela Éditions Caribéennes (Contes de Mort et de Vie aux Antilles, 1976; Contes de Soleil et de Pluie aux Antilles, 1988; Contes de Nuits et de Jours aux Antilles, 1989), e seus reflexos na literatura das Antilhas e da Guiana Francesa. A proposta decolonial também será aplicada à obra Solibo Magnifique, de Patrick Chamoiseau (1991). Para tanto, utiliza-se o conceito de literaturas do desassossego de Gauvin (2016) a fim de opor-se aos conceitos de francofonia e de Littérature-monde – apresentados por Alves (2012) – para designar as literaturas de língua francesa nas Américas, buscando incluí-las nas produções latino-americanas. Percebe-se, assim, grande influência das tradições orais nas produções contemporâneas de escritores antilhanos, além da importância de levar este fato em conta em uma análise que se proponha decolonial dentro da universidade, como discorre Restrepo (2018).Palavras-chave: pensamento decolonial; literatura antilhana de língua francesa; literaturas do desassossego; Ina Césaire; Patrick Chamoiseau.Abstract: This article aims to contribute to the debates on French-speaking cultures through a case study on Antillean Literature according to Decolonial Criticism (WALSH, 2013). The studies about the tradition of creole tales, recorded and translated to French by Ina Césaire and Joëlle Laurant in three bilingual volumes published by Éditions Caribéennes (Contes de Mort et de Vie aux Antilles, 1976; Contes de Soleil et de Pluie aux Antilles, 1988; Contes de Nuits et de Jours aux Antilles, 1989) and its reflections on Antillean and French Guianese Literature will be presented here as decolonial examples. This decolonial approach will also be applied to the work of Solibo Magnifique by Patrick Chamoiseau (1991). In order to do so, the concept of Literatures of Disquiet has been used to oppose the concepts of Francophonie and Littérature-monde – as presented by Alves (2012) – to designate the literature in French language in America aiming to include them in Latin American productions. The influence of oral traditions in contemporary productions by Antillean writers is quite evident, as well how it is important to take this fact into account when proposing a Decolonial analysis inside the academy, as pointed out by Restrepo (2018).Keywords: decolonial thinking; Antillean literature in French; literatures of disquiet; Ina Césaire; Patrick Chamoiseau.


2019 ◽  
Vol 7 (11) ◽  
pp. 12
Author(s):  
Mohammed Bassou

This article puts under scrutiny the religious manifestations in Eliot’s devotional poetry and the meditative questions that he raises. To do so, it limits the scope of my analytical reading to one of his well-known meditative poems, “Ash-Wednesday.”  I shall start with a theoretical analysis of his famous article, “Religion and Literature” and argue for the presence of its milestone ideas in Eliot’s poetry taking “Ash-Wednesday as a case study.” The study also discerns Eliot’s renunciation of the main tenets of Romanticism which he made use of before his conversion.


Sign in / Sign up

Export Citation Format

Share Document