scholarly journals Ūminės klubo ir šlaunies venų trombozės gydymo kateterizacine trombolize ir antikoaguliantais vėlyvųjų rezultatų palyginimas

2004 ◽  
Vol 2 (2) ◽  
pp. 0-0
Author(s):  
Narimantas Markevičius ◽  
Gintaras Apanavičius ◽  
Stanislovas Ščerbinskas ◽  
Marijus Gutauskas ◽  
Vytautas Triponis

Narimantas Markevičius1, Gintaras Apanavičius1, Stanislovas Ščerbinskas2, Marijus Gutauskas1, Vytautas Triponis31 Vilniaus universiteto Kraujagyslių chirurgijos klinika,Vilniaus miesto universitetinės ligoninės I angiochirurgijos skyrius2 Vilniaus universiteto Kraujagyslių chirurgijos klinika,Vilniaus miesto universitetinės ligoninės Rentgenoangiografinių tyrimų skyrius3 Vilniaus universiteto Kraujagyslių chirurgijos klinika,Vilniaus miesto universitetinės ligoninės II angiochirurgijos skyriusAntakalnio g. 57, LT-10305 VilniusEl paštas: [email protected] Įvadas Ūminės proksimalinės giliųjų venų trombozės (GVT) vėlyvosios komplikacijos – potrombozinio sindromo – gydymas yra viena aktualiausių šiuolaikinės medicinos problemų. Taikant naujus perspektyvius gydymo metodus, galima sumažinti šio sindromo pasireiškimo dažnį. Darbe palygintas potrombozinio sindromo dažnis taikant skirtingus ūminės proksimalinės GVT gydymo metodus. Ligoniai ir metodai Vilniaus universiteto Kraujagyslių chirurgijos klinikoje nuo 1998 m. iki 2003 m. gydyta 150 ligonių, kuriems pasireiškė ūminė proksimaline GVT. 60 ligonių taikyta kateterizacinė trombolizė (I grupė), 90 ligonių gydyti tik antikoaguliantais (II grupė). Gydymo rezultatai vertinti po 1, 3, 9 ir 12 mėn. atliekant dvigubą skenavimą, po 6 mėn atliekant ascendentinę ir descendentinę venografijas. Po 16 mėn. nuo buvusios ūminės GVT atlikta visų ligonių anketinė apklausa, pateikiant jiems po 8 klausimus su sistemintais atsakymais. Buvo klausiama apie gydytų ligonių sveikatos, darbingumo, gyvenimo kokybės pokyčius po persirgtos ūminės GVT, o jei pasireiškė potrombozinis sindromas, – ar kreipėsi į gydymo įstaigas ir kiek kartų jose gydėsi. Rezultatai Atliekant dvigubą skenavimą po 12 mėn. nuo ūminės GVT, giliųjų venų vožtuvų nepakankamumas pasireiškė 10 (18%) I grupės ligonių ir 83 (93%) – II grupės. Rekanalizacijos laipsnis I grupėje siekė 99%, II grupėje – 77% Po 16 mėn. nuo persirgtos ūminės proksimalinės GVT buvo išsiųsta 150 anketų ir gauti 106 atsakymai (71%). Savo sveikatos būklę teigiamai įvertino 34 (56%) I grupės ligoniai ir 10 (11%) II grupės. Jokių kojos, kurios gilioji vena buvo užakusi, odos pokyčių nenurodė 56 (93%) I grupės ligoniai ir 23 (26%) – II grupės. Gyvenimo kokybė pablogėjo 4 (7%) I grupės ligoniams ir 42 (47%) II grupės. Darbingumą prarado 6 (10%) I grupės ligoniai ir 39 (43%) II grupės. Dėl potrombozinio sindromo į gydytojus kreipėsi 5 (5%) I grupės ligoniai ir 41 (45%) II grupės. Stacionare potrombozinis sindromas gydytas 2 (3%) I grupės ligoniams ir 40 (44%) II grupės. Išvados Kateterizacinės trombolizės taikymas ištikus ūminei proksimalinei GVT gerokai veiksmingiau apsaugo nuo potrombozinio sindromo negu gydymas tik antikoaguliantais. Tai ekonomiškai efektyvesnis metodas, kadangi vėlyvuoju laikotarpiu daug mažiau ligonių kreipiasi į gydymo įstaigas, gydosi stacionaruose. Kateterizacinė trombolizė daugumai ligonių padeda išlaikyti buvusį iki ligos darbingumą ir gyvenimo kokybę. Reikšminiai žodžiai: giliųjų venų trombozė, potrombozinis sindromas A comparison between long term results of catheter-directed thrombolysis and anticoagulation in the treatment of acute iliofemoral deep vein thrombosis Narimantas Markevičius1, Gintaras Apanavičius1, Stanislovas Ščerbinskas2, Marijus Gutauskas1, Vytautas Triponis3 Background / objective The management of remote complications of acute proximal DVT such as post-thrombotic syndrome is considered to be one of the main problems of modern medicine. The new means of the treatment of post-thrombotic syndrome can contribute to reducing the incidence of this syndrome. The incidence of post-thrombotic syndrome under different measures of DVT treatment is compared. Patients and methods A total of 150 patients with acute proximal DVT were treated at Vilnius University Clinic of Vascular Surgery from 1998 to 2003. Sixty patients were treated by catheter-directed thrombolysis (the first group) and 90 patients by anticoagulation alone (the second group). Treatment results were assessed by duplex ultrasonography at 1, 3, 9 and 12 months and by ascending and descending venography at 6 months of treatment. Following 16 months after the onset of acute DVT, 8-item questionnaires containing organized answers were administered to all the patients. The questionnaire included the assessment of health distress, working performance and the quality of life. Furthermore, this questionnaire assessed whether the patient had been referred to medical institutions due to post-thrombotic syndrome and how many times. Results Duplex ultrasonography performed 12 months after acute DVT revealed development of valvular incompetence in 18% of patients in the first group and in 93% of patients in the second group. The degree of recanalization reached 99% in the first group and 77% in the second group. Following 16 months after acute proximal DVT, 150 questionnaires were dispatched;106 (71%) patients filled in the forms. 34 (56%) patients of the first and 10 (11%) of the second group evaluated their own state of health positively. 56 (93%) patients in the first and 23 (26%) in the second group did not indicate any post-thrombotic skin changes of the affected lower extremity. Quality of life disimproved in 4 (7%) patients in the first group and in 42 (47%) patients in the second group. Working disablement was identified in 6 (10%) and 39 (43%) patients in the first and in the second groups, respectively. 5 (5%) patients in the first group and 41 (45%) in the second group consulted doctors about developing post-thrombotic syndrome. Inpatient treatment for post-thrombotic syndrome was administered to 2 (3%) patients on catheter-directed thrombolysis versus 40 (44%) patients on anticoagulation. Conclusions Catheter-directed thrombolysis for acute proximal DVT has been demonstrated to be a more effective means of post-thrombotic syndrome prophylaxis as compared with anticoagulation alone. Catheter-directed thrombolysis offered a better maintenance of working performance, the quality of life and well-being. Keywords: deep venous thrombosis, posthrombotic syndrome

2019 ◽  
Vol 24 (03) ◽  
pp. 264-269
Author(s):  
Ching Man Yeung ◽  
Alexander Kai Yiu Choi ◽  
Jennifer Wing Sze Tong ◽  
Winnie Fok ◽  
Yat Fai Chan ◽  
...  

Background: Thumb polydactyly is one of the commonest congenital hand differences. Traditional surgeon-based outcome scores capture outcomes mainly on bodily structure and function. Outcomes on the long-term well-being of the patients in the domains of activity and participation are not fully studied. Methods: Forty-eight thumbs in forty-five Chinese patients with radial polydactyly underwent surgical treatment at or before 3 years old were recruited. Mean follow-up was 11.6 years. Surgical outcomes were collected and compared to the normal opposite thumb. The results were compiled into the Japanese Society for Surgery of the Hand (JSSH) score, Cheng score and Tada score. Patients’ activity involving hands were assessed by both objective tools and patient-reported outcome measure while their health-related quality of life (HRQoL) was assessed by Patient- and Parent-reported Pediatric Quality of Life Inventory (PedsQL). Correlations between outcomes were analysed. Results: Overall, both parents and patients themselves reported good quality of life with mean score of 86.6% and 92.1% respectively in PedsQL. The combined surgical scores ranged from 52% good or excellent results using JSSH score to 100% good result using Cheng score. None of the outcomes on bodily structure and function showed positive correlation with patient’s well-being. Negative correlation was noted in total passive range of movement, active movement and Cheng score. All patients reported no activity restriction. Writing test did not show significant slowing. The operated hands had significantly poorer fine motor dexterity than normal. No significant correlation is noted between activity outcomes and PedsQL. Conclusions: Outcomes on bodily structure, function and activity showed little correlation with patients’ well-being after thumb polydactyly correction. It should be careful in using or analysing patient/parent-reported outcome measures on HRQoL as outcome assessment of surgical treatment of radial polydactyly.


GeroPsych ◽  
2019 ◽  
Vol 32 (3) ◽  
pp. 125-134
Author(s):  
Mechthild Niemann-Mirmehdi ◽  
Andreas Häusler ◽  
Paul Gellert ◽  
Johanna Nordheim

Abstract. To date, few studies have focused on perceived overprotection from the perspective of people with dementia (PwD). In the present examination, the association of perceived overprotection in PwD is examined as an autonomy-restricting factor and thus negative for their mental well-being. Cross-sectional data from the prospective DYADEM study of 82 patient/partner dyads (mean age = 74.26) were used to investigate the association between overprotection, perceived stress, depression, and quality of life (QoL). The analyses show that an overprotective contact style with PwD has a significant positive association with stress and depression, and has a negative association with QoL. The results emphasize the importance of avoiding an overprotective care style and supporting patient autonomy.


2020 ◽  
pp. 33-38
Author(s):  
E. Yu. Gan ◽  
L. P. Evstigneeva

Purpose of the study. Assessing the association between the life quality of patients with Sjogren’s Disease and ongoing therapy with various disease-modifying antirheumatic drugs.Material and methods. The study was conducted on the basis of the regional rheumatology center of the consultative diagnostic clinic of the Sverdlovsk Regional Clinical Hospital No. 1. This work is based on the results of a simultaneous study of 74 patients with primary Sjogren’s Disease (SD), distributed in three comparison groups receiving various disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine. The diagnosis of SD was carried out according to European-American criteria AECGC (2002) [18]. In order to analyze the quality of life of patients with SD, the 36-Item Short Form Health Survey (SF‑36) was used. Statistical data processing was carried out using Statistica 7.0 program.Results. Assessment of the quality of life of patients with SD, which is an integrative criterion of human health and well-being, revealed the absence of statistically significant differences (p > 0.05) on eight scales and two health components of the SF‑36 questionnaire in the analyzed groups that differ in the treatment of disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine.Conclusions. The obtained data indicate an equivalent quality of life in SD patients treated with different disease-modifying antirheumatic drugs methotrexate, chlorambucil and hydroxychloroquine, and therefore hydroxychloroquine can be considered as an alternative basic therapy in patients with SD with certain limitations and contraindications methotrexate and chlorambucil.


1970 ◽  
Vol 4 (2) ◽  
Author(s):  
Aan Nuraeni ◽  
Ristina Mirwanti ◽  
Anastasia Anna ◽  
Ayu Prawesti ◽  
Etika Emaliyawati

Prevalensi Penyakit Jantung Koroner (PJK) terus mengalami peningkatan setiap tahunnya dan menjadi masalah kesehatan utama di masyarakat saat ini. PJK berdampak terhadap berbagai aspek kehidupan penderitanya baik fisik, psikososial maupun spiritual yang berpengaruh terhadap kualitas hidup pasien. Isu kualitas hidup dan faktor-faktor yang berhubungan didalamnya belum tergambar jelas di Indonesia. Tujuan dari penelitian ini adalah mengidentifikasi faktor yang memengaruhi kualitas hidup pada pasien PJK yang sedang menjalani rawat jalan. Faktor-faktor yang diteliti dalam penelitian ini meliputi jenis kelamin, tingkat penghasilan, revaskularisasi jantung, rehabilitasi jantung, kecemasan, depresi dan kesejahteraan spiritual. Kecemasan diukur dengan Zung Self-rating Anxiety Scale, depresi diukur dengan Beck Depression Inventory II, kesejahteraan spiritual diukur dengan kuesioner Spirituality Index of Well-Beingdan kualitas hidup diukur menggunakan Seattle Angina Questionnaire. Penelitian ini menggunakan rancangan kuantitatif deskriptif dan analitik multivariatedengan regresi logistic. Diteliti pada 100 responden yang diambil secara randomdalam kurun waktu 1 bulan di Poli Jantung. Hasil penelitian menunjukkan faktor yang memengaruhi kualitas hidup pada pasien PJK adalah cemas (p) 0,002; Odd Ratio(OR) 4,736 (95% confidence interval(CI), 1,749 – 12,827); depresi (p) 0,003; OR 5,450 ( 95% CI, 1,794 – 16,562); dan revaskularisasi (p) 0,033; OR 3,232 (95% CI, 1,096 – 9,528). Depresi menjadi faktor yang paling berpengaruh terhadap kualitas hidup pasien PJK. Faktor yang memengaruhi kualitas hidup pada pasien PJK meliputi depresi, cemas dan revaskularisasi. Dari ketiga variabel tersebut depresi merupakan variabel yang paling signifikan berpengaruh, sehingga manajemen untuk mencegah depresi perlu mendapatkan perhatian lebih baik lagi dalam discharge planningataupun rehabilitasi jantung.Kata kunci: Cemas, depresi, faktor yang memengaruhi, kualitas hidup, spiritual.Factors Influenced the Quality of Life among Patients Diagnosed with Coronary Heart Disease AbstractCoronary Heart Disease (CHD) has affected multidimensional aspects of human live nowadays. Yet, quality of life and factors associated with quality of life among people who live with heart disease has not been explored in Indonesia. This study aimed to identify factors influenced the quality of life among people with CHD received outpatient services. Those factors are gender, income, revascularization, cardiac rehabilitation, anxiety, depression and spiritual well-being. Zung Self-rating Anxiety Scale was used to measure anxiety where depression level measured using Beck Depression Inventory II. Spirituality index was used to measure spiritual well-being. The quality of life level was measured using the Seattle Angina Questionnaire. This study used quantitative descriptive with multivariate analysis using logistic regression. 100 respondents were randomly selected from the Cardiac Outpatient Unit. Findings indicated factors influenced the quality of life of CHD patients using a significance of ƿ-value < 0.005 were: anxiety (ƿ=0,002, OR = 4,736, 95% CI, 1,749 – 12,827); depression (ƿ=0,003; OR=5,450, 95% CI, 1,794 – 16,562); and revascularizations (ƿ=0,033; OR=3,232, 95% CI, 1,096 – 9,528). Depression was considered as the most significant factor; therefore, managing depression is a priority in the discharge planning or cardiac rehabilitation programme. Keywords: Anxiety, depression, quality of life, spiritual, well-being.


2020 ◽  
Vol 16 (4) ◽  
pp. 730-744
Author(s):  
V.I. Loktionov

Subject. The article reviews the way strategic threats to energy security influence the quality of people's life. Objectives. The study unfolds the theory of analyzing strategic threats to energy security by covering the matter of quality of people's life. Methods. To analyze the way strategic threats to energy security spread across cross-sectoral commodity and production chains and influences quality of people's living, I applied the factor analysis and general scientific methods of analysis and synthesis. Results. I suggest interpreting strategic threats to energy security as risks of people's quality of life due to a reduction in the volume of energy supply. I identified mechanisms reflecting how the fuel and energy complex and its development influence the quality of people's life. The article sets out the method to assess such quality-of-life risks arising from strategic threats to energy security. Conclusions and Relevance. In the current geopolitical situation, strategic threats to energy security cause long-standing adverse consequences for the quality of people's life. If strategic threats to energy security are further construed as risk of quality of people's life, this will facilitate the preparation and performance of a more effective governmental policy on energy, which will subsequently raise the economic well-being of people.


2019 ◽  
Author(s):  
Zahari Ishak ◽  
Suet Fin Low ◽  
Wan Abdul Hakim Wan Ibrahim ◽  
Abqariyah Yahya ◽  
Fuziah Md. Zain ◽  
...  

<p>Obesity has been shown to impact the health-related quality of life (HRQOL) among children. This study aimed to determine the effectiveness of MyBFF@school program on HRQOL among overweight and obese primary school children in Malaysia. KINDL<sup>R</sup> Questionnaire was used to collect data on their HRQOL before and after the program. ANCOVA was used to analyse the comparison between intervention and control group after 6 months. There are significant effect on family functioning, F(2,1103)=7.452, p<0.05 and school functioning, F(1,1117)=7.103, p<0.05 after the intervention. Effects can also be seen on physical well-being, emotional well-being and friends functioning. The program is effective in improving the HRQOL significantly in two dimensions namely the family and school functioning. In order to achieve greater overall success,social support should be an integral part of the program and stigma on obesity should be managed and reduced by including normal-weight children in the program.</p>


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