scholarly journals Hysteroscopic evaluation of uterine cavity in women with unexplained infertility

2021 ◽  
Vol 12 (6) ◽  
pp. 375-378
Author(s):  
Nesreen Abd El Fattah Abd Allah Shehata ◽  
Hamada AA Ali ◽  
Rabab Ashour ◽  
Momen Z El nadeim ◽  
Nesreen AA Shehata ◽  
...  
Keyword(s):  
Uterine Cavity ◽  
Unexplained Infertility ◽  
P Value ◽  
Office Hysteroscopy ◽  
University Hospitals ◽  
Intrauterine Adhesions ◽  
Secondary Infertility ◽  
Infertile Women ◽  
Significant Difference ◽  
Work Up

Objective: To detect missed uterine abnormalities on primary work up in unexplained infertile women. Study design: An observational study was performed in the outpatient infertility clinic of Beni-Suef University Hospitals. It included 100 women with unexplained infertility. Diagnostic office hysteroscopy was done for all participants. Women were grouped according to the infertility type and compared as regards uterine abnormalities detected. Results: Uterine abnormalities were detected by hysteroscopy in 29% of women. No significant difference was found regarding the hysteroscopic findings between primary and secondary infertility groups. However, uterine polyp cases were detected more in women with primary infertility (55.5% /18). A significant difference in intrauterine adhesions between both groups being detected only in secondary infertility group (p value =0.006). Conclusion: Outpatient preliminary and routine diagnostic office hysteroscopy may be a beneficial part of a primary and secondary infertility workup.

scholarly journals Hysterosalpingographic Evaluation of Uterus and Fallopian Tubes of Infertile Women

2017 ◽  
Vol 6 (1) ◽  
pp. 63-71 ◽  
Author(s):  
Manoj Bhattarai ◽  
Sita Pokhrel Ghimire
Keyword(s):  
Fallopian Tube ◽  
Uterine Cavity ◽  
Categorical Variables ◽  
P Value ◽  
Fallopian Tubes ◽  
Secondary Infertility ◽  
Radiological Investigation ◽  
Infertile Women ◽  
Primary Infertility ◽  
Significant Difference

Background: Hysterosalpingography (HSG) is a routinely performed radiological investigation for evaluation of uterine cavity morphology and fallopian tube patency in infertile women. This study was undertaken to describe patterns of HSG findings and to assess any significant difference in uterine and fallopian tube findings in women with primary and secondary infertility in eastern part of Nepal.Material and Methods: Hospital based cross sectional descriptive study was conducted by retrospectively analyzing HSG records of 216 infertile women (both primary and secondary infertility) done from April 2014 to August 2016. Radiological findings in uterus and fallopian tubes were recorded and analyzed. Association between two categorical variables was examined by Chi-square test.Results: Majority of infertile women (53.2%) had primary infertility. Abnormal HSG was seen in 44.9% infertile women and higher in secondary infertility (57.4%) than with primary infertility (33.9%) (OR = 2.63, 95% CI = 1.51 – 4.57, P value = 0.001). Tubal abnormality was common than uterine abnormality (36.1% versus 8.8%, P value= 0.001). Tubal abnormalities were higher in women with secondary infertility than with primary infertility (52.5% versus 21.7%), whereas uterine abnormalities were common with primary infertility compared to secondary infertility (12.2% versus 5.0%) (P value= 0.001).Conclusion: Abnormal HSG was more associated with secondary infertility. Infertility was significantly associated with tubal abnormality than with uterine abnormality. Tubal abnormalities are common in women with secondary infertility whereas uterine abnormalities are common in women with primary infertility and are statistically significant.Journal of Nobel Medical CollegeVolume 6, Number 1, Issue 10 (January-June, 2017), Page: 63-71

scholarly journals Quality of Life among Infertile Women Attending an Infertility Treatment Center, Kathmandu

2020 ◽  
Vol 18 (3) ◽  
pp. 394-400
Author(s):  
Subhadra Pradhan Shrestha ◽  
Sushila Devi Bhandari ◽  
Sushaili Pradhan
Keyword(s):  
Quality Of Life ◽  
Infertility Treatment ◽  
Reproductive Age ◽  
Treatment Center ◽  
P Value ◽  
Secondary Infertility ◽  
Infertile Women ◽  
Low Level ◽  
Significant Difference

Background: The problem of infertility is an increasing issue worldwide, among married reproductive age couples, particularly women. Infertility can affect every aspect of quality of life among infertile women. This study aimed to assess the quality of life of infertile women attending an infertility treatment center. Methods: A crossectional  study of 385 infertile women age 25-50 years attending an infertility treatment center was carried out from 8th July 2018 to 4th January 2019. Data were collected using the Short Form Health Survey (Rand SF-36), containing 36 questions by interview technique and analyzed using descriptive and inferential statistics. Results: The higher proportion (63.38%) of primary infertility was involved in this study compared to secondary infertility without baby (24.93%) and with the baby (11.69%). More than half (54.5%) of infertile women had low-level quality of life whereas 45.5% of them had a high level of quality of life. The mean scores of quality of life subscales were not significantly different between primary and secondary infertility (p-value >0.05). There was no statistically significant association between socio-demographic variables and quality of life of primary and secondary infertility (p-value >0.05). There was a statistically significant difference between the duration of infertility and quality of life of primary and secondary infertility with baby (p-value 0.020), and between the reason of infertility and quality of life of secondary infertility without a baby (p-value 0.010). Conclusions: A high proportion of infertile women had low-level quality of life. Therefore, it is necessary to provide them information, education, and counseling regarding infertility. Keywords: Infertility treatment center; infertile women; quality of life

scholarly journals Dietary lifestyle modifications for vitiligo patients

2019 ◽  
Vol 10 (4) ◽  
pp. 45
Author(s):  
Sahar A. Abd-El Mohsen ◽  
Azhar A. Mohamed
Keyword(s):  
Research Design ◽  
Rural Areas ◽  
P Value ◽  
University Hospitals ◽  
Lifestyle Modifications ◽  
Dermatology Department ◽  
Patient Interview ◽  
Significant Difference ◽  
Post Test ◽  
Quasi Experimental

Background and objective: Changing the patient lifestyle as regarding diet well helped in vitiligo patient cure. Aim: to examine the effect of applying dietary instructions on dietary lifestyle modifications of vitiligo patients.Methods: Research design: Quasi experimental research design with one group (Pre/Post-test) was utilized in this study. Setting: the study was conducted in the ultraviolet unit at the Dermatology Department of Asyut University Hospitals. Study tool: Structured patient interview questionnaire sheet. It included two parts: Part 1: Assessment of patient’s sociodemographic variables. Part 2: Dietary pattern assessment: derived from Patient Life Style Pattern Assessment Sheet (PLSPAS) for Vitiligo.Results: The mean age of the studied sample was (mean ± SD 34.62 ± 12.35), 51.6% were female, 70% were living in rural areas, a highly statistically significant difference in the total mean knowledge scores between pre and post application of the dietary instructions (p value = .002).Conclusions: The present study concluded that there was a great improvement in the dietary lifestyle pattern of the studied sample after application of dietary instructions. Recommendations: Replication of the study on a larger probability sample from different geographical locations for generalization of the results. Printing copies of the dietary instructions for dissemination among all vitiligo patients attending the dermatology ward for treatment or follow-ups.

scholarly journals Investigating Hysteroscopy Implementation in Infertile Women Candidate With a Normal Uterine Cavity for Laparoscopy in Hysterosalpingography

2018 ◽  
Vol 7 (1) ◽  
pp. 79-84
Author(s):  
Maliheh Amirian ◽  
Anis Darvish Mohammadabad ◽  
Negar Morovatdar ◽  
Leili Hafizi
Keyword(s):  
Diagnostic Laparoscopy ◽  
False Negative ◽  
Uterine Cavity ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Endometrial Polyps ◽  
Infertile Women ◽  
Submucous Myoma ◽  
Age Range

Objectives: Endometrial pathologies inside the cavity can occur simultaneously with gestational unpleasant consequences but are not always capable of being diagnosed by the hysterosalpingography (HSG). This study aimed to examine the value of performing diagnostic hysteroscopy beside diagnostic laparoscopy among infertile women with normal uterine cavities in HSG. Materials and Methods: A total of 103 infertile women with normal uterine cavities in the HSG and within the age range of 18-40 who referred to Imam Reza hospital for laparoscopy during 2016-2017 were included in this cross-sectional study. Hysteroscopy was performed simultaneously with diagnostic laparoscopy. Then, the existence of uterine pathologies like endometrial polyps, submucous myoma, and uterine endometrial adhesions and their relationship with the patient’s age, infertility type and duration, and cycle time were evaluated. A P value less than 0.05 was considered statistically significant. Results: Overall, 64 patients (63.1 %) had a normal uterine cavity in the hysteroscopy while 39 of them had an abnormal uterine cavity, the HSG false negative cases of whom were reported 37.9%. The pathologies found in the hysteroscopy were endometrial polyp (16 cases), submucous myoma (1 case), uterine septum (6 cases), asherman syndrome (7 cases), bicornuate uterus (4 cases), polyp + asherman (3 cases), polyp + submucous myoma (1 case), and septum + submucous myoma (1 case). Patients’ age, type of infertility, and menstruation time during performing hysteroscopy made no particular difference in diagnosing pathologies of the uterine cavity in the hysteroscopy. Conclusions: Based on the findings, conducting hysteroscopy in infertile women who are candidates of laparoscopy and have normal uterine cavities in HSG can result in recognizing some cases of uterine pathologies which influence the outcomes of future pregnancies is not dependent upon the patient’s age, menstruation time, type and duration of infertility, and result of laparoscopy.

scholarly journals ADA activity in the follicular fluid of infertile women with diminished ovarian reserve can act as a predictor of ovarian reserve

2021 ◽  
Vol 10 (2) ◽  
pp. 452
Author(s):  
Gülşah İlhan ◽  
Besim H. Bacanakgil ◽  
Ayşe Köse ◽  
Ayben Atıcı ◽  
Şener Yalçınkaya ◽  
...  
Keyword(s):  
Follicular Fluid ◽  
Ovarian Reserve ◽  
Reproductive Tract ◽  
Vitro Fertilization ◽  
Infertile Women ◽  
Significant Difference ◽  
Human Reproductive ◽  
Ovarian Reserve Markers ◽  
Work Up

Background: Adenosine deaminase (ADA) catalyses the deamination of adenosine to inosine. In the human reproductive tract, the importance of enzymes that affect metabolism of adenosine, particularly ADA, has been emphasized. It is aimed to evaluate the plasma and follicular fluid (FF) activities of total ADA (ADAT) in infertile women and to determine its relation with ovarian reserve markers and in vitro fertilization (IVF) outcomes.Methods: Plasma and FF activities of ADAT were measured in 106 infertile women. Its relation with ovarian reserve markers and IVF outcomes were determined.Results: There was a significant difference in the ADAT activities between plasma and FF of infertile women (p<0.01). The activity of plasma ADAT was higher than FF ADAT in infertile women (p<0.01). The activity of FF ADAT in DOR group was higher than that of the others (p<0.01). In DOR group; the activity of FF ADAT activity had a negative correlation with BMI and a positive correlation with FSH and no relation with IVF outcomes.Conclusions: Increased ADAT activity can lead to reduced adenosine levels, which might be resulted in disturbed fertility process. The activity of FF ADAT activity might be important for fertility work-up. Further studies are needed.

scholarly journals Frequency of Chlamydia trachomatis Infection in Spontaneous Abortion of Infertile Women During First Pregnancy Referred to Tabriz University of Medical Sciences by Nested PCR Method in 2015

2018 ◽  
Vol 7 (4) ◽  
pp. 526-230
Author(s):  
Mehdi Haghdoost ◽  
Sanaz Mousavi ◽  
Mehdi Khanbabayi Gol ◽  
Majid Montazer
Keyword(s):  
Spontaneous Abortion ◽  
Nested Pcr ◽  
Control Method ◽  
Transmitted Disease ◽  
Infertility Treatment ◽  
P Value ◽  
Medical Sciences ◽  
Infertile Women ◽  
Significant Difference ◽  
Pcr Method

Objectives:Chlamydia trachomatis, as the main cause of bacterial sexually transmitted disease (STD), can lead to serious complications such as spontaneous abortion. Therefore, the aim of this study was to determine the frequency of C. trachomatis infection in spontaneous abortion of infertile women who referred to Tabriz University of Medical Sciences during the first pregnancy by means of nested polymerase chain reaction (PCR) method in 2015. Materials and Methods: The present descriptive, cross-sectional study was performed in the infertility clinics of Tabriz University of Medical Sciences from March 21, 2015 to March 19, 2016. A total of 120 infertile women were selected by the convenience sampling method. The specimens were prepared by the Dacron swab after four rotations in the endocervix and discharged into the specific transport medium of C. trachomatis. The DNA extraction was then performed by AccuPrep genomic DNA kit and the DNA was extracted until performing the PCR at -20° C. Next, nested PCR was conducted in 2 rounds and the final product of PCR was agar -2% gel electrophoresis. After entering the data in SPSS, the chi-square test was used to examine the role of factors influencing C. trachomatis infection and a P value less than 0.05 was considered significant. Results: The incidence of C. trachomatis infection in women with spontaneous abortion was 16.66%. In addition, there was a significant difference between the infected and non-infected groups regarding employment (P<0.04), birth control method (P<0.03), and the number of sexual intercourses per week (P<0.001). Conclusions: The prevalence of C. trachomatis in women who became pregnant with infertility treatment and spontaneous abortion was high in this study. Thus, nested PCR is considered an appropriate method for the diagnosis of C. trachomatis and it is essential for pregnant women who experience pregnancy with infertility treatment.

scholarly journals Accuracy of a new hysteroscopic method in the assessment of tubal patency: Hysteroscopic Chromotubation

2018 ◽  
Vol 24 (2) ◽  
pp. 82
Author(s):  
Burak Yucel ◽  
Emine Demirel ◽  
Sefa Kelekci ◽  
Kerem Doga Seckin ◽  
Osama Shawki
Keyword(s):  
Methylene Blue ◽  
Cohort Study ◽  
Gold Standard ◽  
Uterine Cavity ◽  
High Sensitivity ◽  
Office Hysteroscopy ◽  
Predictive Values ◽  
Tubal Patency ◽  
Infertile Women ◽  
Sensitivity Specificity

<p><strong>Objective</strong></p><p>The aim of this study was to evaluate the diagnostic accuracy of hysteroscopic chromopertubation (HCT) in the assessment of tubal patency by comparing its results with laparoscopic chromopertubation (LCT).</p><p><strong>Study Design</strong></p><p>The population of this prospective cohort study consisted of both fertile and infertile women. Sixty-four women were included to the study. HCT was assessed by the observation of the transport of highly concentrated methylene blue from uterine cavity to tubal ostia. The results of HCT were compared with the results of LCT as a gold standard. The accuracy of HCT, sensitivity, specificity, positive and negative predictive values in diagnosing tubal patency were calculated.<strong></strong></p><p><strong>Results</strong></p><p>The results of HCT and LCT were evaluated for right and left tubes, separately. One hundred and twenty-eight tubes were determined. Sensitivity, specificity, positive and negative predictive values for HCT were; 85.85%, 59.09%, 91% and 46.43%, respectively.</p><p><strong>Conclusion </strong></p><p>This study’s result showed that HCT had high sensitivity and moderate specificity values in the assessment of tubal patency. HCT during office hysteroscopy could give the chance to practitioners to assess tubal patency without subjecting the patient to multiple procedures.<strong></strong></p>

scholarly journals Office hysteroscopy prior to ART cycle-analysis and outcome at a private IVF clinic setup in Surat, Gujarat, India

2017 ◽  
Vol 6 (2) ◽  
pp. 611
Author(s):  
Meeta Mohan Mahale ◽  
Purnima Kishore Nadkarni ◽  
Kishore Mohan Nadkarni ◽  
Pooja Prabhakar Singh ◽  
Aditi Akshay Nadkarni ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Pregnancy Rate ◽  
Multiple Pregnancy ◽  
Uterine Cavity ◽  
Standard Test ◽  
Office Hysteroscopy ◽  
Miscarriage Rate ◽  
Infertile Women ◽  
Diagnostic Hysteroscopy ◽  
Multiple Pregnancy Rate

Background: Hysteroscopy is a gold standard test for assessing the uterine cavity. The presence of uterine pathology may negatively affect the chance of implantation .This study investigated the use of routine office hysteroscopy and correction of any intrauterine pathologies prior to starting IVF cycle on treatment outcome in women seeking IVF treatment for primary infertility and recurrent implantation failure.Methods: This was a retrospective study of 100 women who attended our infertility clinic from July 2016 to December 2016 and who were willing for office hysteroscopy. The main outcomes measured were clinical pregnancy rates achieved in the index IVF cycle, multiple pregnancy rate, ectopic pregnancy rate, miscarriage rate and failure rate.Results: Of the 100 patients who participated in the study, 75 patients conceived, 25 patients failed to conceive. 80.64% patients with normal findings on diagnostic hysteroscopy conceived after the procedure, 58.33% patients conceived after polypectomy, 68.42% conceived after septal resection, 71.42% conceived after adhesiolysis, 50% conceived after lateral metroplasty and 73.07% of recurrent implantation failure conceived after local endometrial injury was done on hysteroscopy.Conclusions: Hysteroscopy in infertile women prior to their IVF cycle when performed atleast 3 months in advance could improve treatment outcome.

scholarly journals Povidone-iodine versus normal saline solution in preoperative vaginal cleansing before office hysteroscopy: a randomized controlled trial

2017 ◽  
Vol 7 (1) ◽  
pp. 5
Author(s):  
Ahmed M. Abbas ◽  
Asmaa S. Shaltout ◽  
Shymaa S. Ali ◽  
Armia Michael ◽  
Ahmed Altraigey ◽  
...  
Keyword(s):  
Normal Saline ◽  
Povidone Iodine ◽  
Controlled Trial ◽  
Uterine Cavity ◽  
Office Hysteroscopy ◽  
Postoperative Infections ◽  
Postoperative Fever ◽  
Group I ◽  
Significant Difference ◽  
The Difference

Background: Hysteroscopy is well-thought-out the gold standard for assessing the uterine cavity, and now can be done as an office process due to enhanced endoscopic advances with no need to in-patient admission. Objective of the present study was to compare the difference in the rate of postoperative vaginal irritation symptoms and postoperative infections after using povidone iodine (PI) and normal saline (NS) solution in vaginal cleaning before outpatient office hysteroscopy (OH).Methods: Women attended to the hospital for diagnostic OH were included for present study. Eligible women were randomly allocated in a 1:1 ratio to two groups. Group I "PI group" women exposed to PI for vaginal cleansing before hysteroscopy, and group II "NS group” women exposed to the NS solution for vaginal cleansing. The primary outcome of the study was to compare the difference in the rate of postoperative vaginal irritation symptoms and postoperative infections in both groups.Results: The mean age of the study participants was 34.26±4.14 years for NS group compared to 35.22±4.01 years for PI group (p=0.652). The PI group reported higher rate of vaginal irritation than NS group with no statistically significant difference between the two groups (p=0.179). Both groups were similar in postoperative fever, urinary tract infection and vaginitis (p>0.05).Conclusions: This study concluded that preoperative vaginal disinfection at the time of OH with a NS solution is less frequently causing postoperative vaginal irritation symptoms. Additionally, it is as effective as the usual agent (PI) in preventing postoperative infections.

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