scholarly journals Protective Role of Herbal Drugs in Diabetic Neuropathy: An Updated Review

2018 ◽  
Vol 6 (1) ◽  
pp. 21-30
Author(s):  
Eshita Sharma ◽  
Tapan Behl ◽  
Monika Sachdeva ◽  
Rashita Makkar ◽  
Sandeep Arora
Keyword(s):  
Health Care ◽  
Neuropathic Pain ◽  
Medicinal Plants ◽  
Diabetic Neuropathy ◽  
Review Paper ◽  
Protective Role ◽  
Herbal Drugs ◽  
Herbal Plants ◽  
Ancient Times

Medicinal plants play a beneficial role in health care and are commonly used in preventing and testing diseases and specific ailments. The advantage associated with herbals plants are numerous and cannot be ignored as they have less adherence issues and are accepted widely by the population due to greater belief in Ayurveda since ancient times. Neuropathic pain has immersed as a serious threat to patient that occurs by damaging the blood vessels leading to morbidity and mortality. The present review paper aims in providing an account of various herbal plants that could be employed in treatment of neuropathic pain.

PROTECTIVE ROLE OF FICUS RACEMOSA IN DIABETES INDUCED NEUROPATHY: STRUCTURAL AND FUNCTIONAL EVIDENCES

INDIAN DRUGS ◽  
2017 ◽  
Vol 54 (11) ◽  
pp. 58-60
Author(s):  
N Solanki ◽  
◽  
S. K Bhavsar
Keyword(s):  
Sciatic Nerve ◽  
Diabetic Neuropathy ◽  
Ethanolic Extract ◽  
Protective Role ◽  
Diabetic Rats ◽  
Dependent Manner ◽  
Traditional System ◽  
Ficus Racemosa ◽  
Dose Dependent

Ficus racemosa is used in traditional system of medicine for various health problems and diseases, and is commonly known as Gular fig. The main objective was to study its effects against streptozotocin induced diabetic neuropathy by structural and functional marker. Investigation of diabetic neuropathy was carried out through functional and structural assessment in streptozotocin induced in diabetic rats. Diabetic rats were treated for 28 days in dose dependent manner of Ficus racemosa aqueous extract (250 mg/kg and 500 mg/kg) and ethanolic extract (200 mg/kg and 400 mg/kg). Study showed marked protection observed by Ficus racemosa in hippocampus region of brain and sciatic nerve tissues. Ficus racemosa treatment showed improvement in functional and structural markers, which strongly suggest its protective role in diabetic neuropathy.

Alternative treatment strategies for neuropathic pain: Role of Indian medicinal plants and compounds of plant origin-A review

2017 ◽  
Vol 92 ◽  
pp. 634-650 ◽  
Author(s):  
Hasandeep Singh ◽  
Sakshi Bhushan ◽  
Rohit Arora ◽  
Harpal Singh Buttar ◽  
Saroj Arora ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Medicinal Plants ◽  
Alternative Treatment ◽  
Treatment Strategies ◽  
Plant Origin ◽  
Indian Medicinal Plants

scholarly journals Author response: Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain

2020 ◽  
Author(s):  
David Cabañero ◽  
Angela Ramírez-López ◽  
Eva Drews ◽  
Anne Schmöle ◽  
David M Otte ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Protective Role ◽  
Author Response ◽  
Cb2 Receptors ◽  
Cannabinoid Cb2 Receptors

scholarly journals Plants as Immunity Enhancers: A Review

2021 ◽  
Vol 23 (08) ◽  
pp. 92-106
Author(s):  
◽  
Payal Mittal ◽  
Keyword(s):  
Immune System ◽  
Medicinal Plants ◽  
Research Area ◽  
Present Review ◽  
Active Principle ◽  
Active Constituents ◽  
Herbal Plants ◽  
Ancient Times

It is an evident from ancient times that herbs and medicinal plants have the potential to cure a variety of diseases. Some plants boosts our immunity and make our immune system more powerful to fight againt various diseases. The medicinal effects shown by the plants are due to active principle compound present in them and they work in the same manner as the conventioal drugs. Indian herbs and medicinal plants show miraculous effects against wide variety of diseases and disorders in humansand can be better called as “elixers of life”. Currently, the interest is increasing with high pace in the use of active constituents of medicinal plants as modulator or enhancer of complex immune system. From the literature of various studies carried out in the research area , it is culminated that many of the chemicals in the form of alkaloids, flavanoids, anti-oxidants, tannins, terpenes, and glycoside products are responsible to empower the immunmodulator effect. Keeping in mind , the appreciating potential of active constituents of medicinal plants and their derived drugs, present review is an attemptto globally popularize the herbal plants with Immunomodulator Activity.

scholarly journals Role of Flavonoids against COVID-19

2021 ◽  
Vol 9 (1) ◽  
pp. 47-55
Author(s):  
Ambreen Fatima ◽  
Yasir H. Siddique
Keyword(s):  
Treatment Strategy ◽  
Protective Role ◽  
The Novel ◽  
Loss Of Life ◽  
The World ◽  
Health Promoting ◽  
Ancient Times ◽  
Novel Coronavirus ◽  
Old Drugs

The novel coronavirus disease (COVID-19) has entered a threatening stage all over the world. Many lives have been lost, and many more are in need of treatment. The mild symptoms may include fever and dry cough, but in severe cases, it could lead to pneumonia and ultimately death in some instances. Though medical scientists all over the globe are working hard to develop a treatment for this disease, yet no definite cure has been found. To date, the treatment strategy is based on adopting strategies to break the transmission of the virus and repurposing of the old drugs to prevent the loss of life. Among the various potent candidates, flavonoids may play a protective role in these times. Studies have already proven various health-promoting properties of flavonoids in earlier viral diseases, like SARS and MERS. Since ancient times, been plants have used to treat a number of human diseases. Different phytoproducts have been previously described to inhibit the replication of numerous viruses. Despite the positive reports for plant-based medications, no successful clinical trials on phytoproducts as anti-COVID agents have been conducted to date. This review highlights the efficacy of flavonoids as a treatment strategy either alone or in combination with other drugs.

scholarly journals Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
David Cabañero ◽  
Angela Ramírez-López ◽  
Eva Drews ◽  
Anne Schmöle ◽  
David M Otte ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Immune Cells ◽  
Protective Role ◽  
Spontaneous Pain ◽  
Wild Type ◽  
Self Administration ◽  
Psychotropic Effects ◽  
Peripheral Immune Cells ◽  
Simultaneous Activity

Cannabinoid CB2 receptor (CB2) agonists are potential analgesics void of psychotropic effects. Peripheral immune cells, neurons and glia express CB2; however, the involvement of CB2 from these cells in neuropathic pain remains unresolved. We explored spontaneous neuropathic pain through on-demand self-administration of the selective CB2 agonist JWH133 in wild-type and knockout mice lacking CB2 in neurons, monocytes or constitutively. Operant self-administration reflected drug-taking to alleviate spontaneous pain, nociceptive and affective manifestations. While constitutive deletion of CB2 disrupted JWH133-taking behavior, this behavior was not modified in monocyte-specific CB2 knockouts and was increased in mice defective in neuronal CB2 knockouts suggestive of increased spontaneous pain. Interestingly, CB2-positive lymphocytes infiltrated the injured nerve and possible CB2transfer from immune cells to neurons was found. Lymphocyte CB2depletion also exacerbated JWH133 self-administration and inhibited antinociception. This work identifies a simultaneous activity of neuronal and lymphoid CB2that protects against spontaneous and evoked neuropathic pain.

scholarly journals ANTI-DIABETIC PHARMACOTHERAPEUTIC POTENTIALS OF SOME INDIAN MEDICINAL PLANTS: INSIGHTS INTO THE NATURAL ARMAMENTARIUM

2021 ◽  
Vol 21 (No 1) ◽  
Author(s):  
Ashima Gakhar
Keyword(s):  
Medicinal Plants ◽  
Endocrine System ◽  
Industrialized Countries ◽  
Vast Number ◽  
Chemical Agents ◽  
Family Names ◽  
Active Chemical ◽  
Herbal Plants ◽  
Indian Medicinal Plants

Herbal medication has grown exponentially in popularity in recent years, gaining popularity in both emerging and industrialized countries due to its natural origins and lack of side effects. To compile knowledge regarding medicinal plants used to cure diabetes mellitus, a systematic study was performed. It is a metabolic disease of the endocrine system that affects about 10% of the world’s population, with the number of people afflicted growing by the day. The profiles provide details on the scientific and family names of the plants, plant sections and research models used, hypoglycemic behavior, and active chemical agents. The vast number of plants mentioned in this analysis exemplified the role of herbal plants in diabetes care. These plants’ effects can help to delay the onset of diabetic complications and correct metabolic imbalances. This study encourages researchers to do further studies into the possible usage of medicinal plants with anti-diabetic properties.

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