Lacunar Skull Deformity and Intelligence

PEDIATRICS ◽  
1977 ◽  
Vol 59 (2) ◽  
pp. 296-299
Author(s):  
Marvin A. Fishman ◽  
Helen S. Palkes ◽  
Gary D. Shackelford ◽  
William H. McAlister

Prognostic criteria to be utilized in the selection of neonates with myelomeningoceles for early treatment have been proposed by Lorber.1 Stein et al. suggested modification of the selection factors based on the presence or absence of lacunar skull deformity (LSD) which they thought to be a good predictor of subsequent intellectual development.2 However, disagreement exists regarding the value of LSD as a useful criterion in early selection for treatment because Lonton et al. found only minor differences in intelligence among groups of patients with varying degrees of the deformity.3 In this report, a population of children with myelomeningoceles was studied in an effort to reach definite conclusions regarding the association between LSD and intelligence. See table in the PDF file

2021 ◽  
Vol 47 (2) ◽  
pp. 88-95
Author(s):  
José Luis Pires ◽  
Edna Dora Martins Newman Luz ◽  
Antônio Alves Pimenta Neto

ABSTRACT Progenies from 69 crosses between parents obtained by recurrent selection for resistance and yield were inoculated with Moniliophthora perniciosa basidiospores. The symptoms were evaluated and compared with those in the equally inoculated progenies of Catongo, SIC 23 and SCA 6. Forty-three of the new progenies did not differ statistically from SCA 6, while 10 new progenies were statistically better than this control. The female parents that can be highlighted are (P4B x SCA 6), (MA 16 x SCA 6), (CEPEC 86 x SCA 6), and the EET 75 clone. The best male parents were (CAB 214), (CAB 208) and (P4B x OC 67), which did not differ from each other. This study proved the existence of gene combinations between fathers and mothers, the occurrence of additive effects and the dominant inheritance of these factors, which should allow the selection of clones with higher resistance levels and durability.


2018 ◽  
Vol 53 (3) ◽  
pp. 279-286
Author(s):  
Ivar Wendling ◽  
José Alfredo Sturion ◽  
Carlos André Stuepp ◽  
Cristiane Aparecida Fioravante Reis ◽  
Magno Antonio Patto Ramalho ◽  
...  

Abstract: The objective of this work was to evaluate the feasibility of early selection of open-pollinated yerba mate (Ilex paraguariensis) progenies, and to classify the best parents and candidates for clones. The germplasm is composed of 140 progenies collected from areas within the natural distribution of the species in Southern Brazil and a commercial genotype (control). The experiment was established in Ivaí, in the state of Paraná, Brazil, in March 1997, in randomized complete blocks, with ten replicates, and linear plots of six plants. The commercial mass (kg per plant) of leaves and branches smaller than 7 mm was harvested at 2.5, 4.5, 6.5, and 18.7 years of age. The statistical evaluation was performed using the mixed model procedure with restricted maximum likelihood/best linear unbiased prediction, using the Selegen software. High selective accuracy, significant progeny effects, and genetic variability for commercial mass production were observed for the four harvesting ages. The application of early selection for leaf mass production is feasible for yerba mate progenies harvested at 6.5 years. The selection of the best trees, either for use as parents or as candidates for cloning, provides significant gains for the genetic breeding of yerba mate.


2018 ◽  
Vol 53 (9) ◽  
pp. 1018-1024 ◽  
Author(s):  
Cláudia Burin ◽  
Dilson Antônio Bisognin ◽  
Kelen Haygert Lencina ◽  
Eliseo Salvatierra Gimenes

Abstract: The objective of this work was to define an early selection strategy to identify Cabralea canjerana (Meliaceae) clones with high multiplication rate. A mini-garden of 109 clones of canjerana seedlings was established in a completely randomized design, in an acclimatized greenhouse. From seedlings, the mini-stumps and mini-cuttings were obtained. Mini-cuttings were collected at five different times, and the number of mini-cuttings per mini-stump, rooting percentage, and number of rooted mini-cuttings were quantified. The number of rooted mini-cuttings per mini-stump was the only trait that showed high correlation with the others. Five groups of clones based on the number of rooted mini-cuttings per mini-stump were separated using k-means clustering, and the genetic gain from selection and Pearson correlation were estimated. The selection of the two best groups in each evaluation period resulted in high genetic gains from selection for all evaluated traits. Early selection for the number of rooted mini-cuttings discarded 65% of the evaluated clones, which increases experimental precision in evaluations of traits associated with plantlet growth and quality. Early selection for the number of rooted mini-cuttings per mini-stump at different times allows the identification of Cabralea canjerana clones with high multiplication rate.


2015 ◽  
Vol 15 (3) ◽  
pp. 169-174 ◽  
Author(s):  
José Maria Villela Pádua ◽  
Magno Antonio Patto Ramalho ◽  
Ângela de Fátima Barbosa Abreu

It is questionable if early selection for resistance to Colletotrichum lindemuthianum reduces the efficiency of selection for grain yield in common beans. For this, it was used the segregating population of the cross between two common bean lines: CI107 (susceptible) x BRSMG Madrepérola (resistant). Selection for resistance was carried out in F2and F3, obtaining three types of progenies: not selected (A), selected only in F2(B), and selected in F2and F3(C). The progenies obtained were evaluated for grain yield and pathogen occurrence in experiments. In F3:5, it was used 289 treatments (96 progenies A, 96 B, 95 C and 2 checks (T)); in F3:6, 196 treatments (64 A, 64 B, 64 C and 4 T); in F3:7, 81 treatments (26 A, 26 B, 26 C and 3 T). Selection of plants resistant to anthracnose in early generations increases the successful selection for grain yield in later generations.


2016 ◽  
Vol 40 (2) ◽  
pp. 255-267
Author(s):  
Poliana Coqueiro Dias ◽  
Aloisio Xavier ◽  
Marcos Deon Vilela de Resende ◽  
Fabrício Antonio Biernaski ◽  
Regiane Abjaud Estopa ◽  
...  

ABSTRACT This study aimed to estimate the genetic correlation among selection ages (juvenile - adult) and efficiency of early selection for the height, diameter, and volume traits of individuals from Pinus taeda families propagated via somatic embryogenesis. This study was carried out by genetic-statistical analysis, estimation procedure of variance (Reml), and prediction components of breeding values (Blup), using the Selegen-Reml/Blup software. Genetic correlations among juvenile ages and rotation age were performed by applying the linear model developed by Lambeth (1980). In accordance with results of the established model, the early selection can be performed in clones of Pinus taeda with high selection efficiency. Ages from 4 to 6 years old are enough to select Pinus taeda clones propagated via somatic embryogenesis for harvesting at 8 and 12 years old; and 6 to 10 years old are enough to select them for harvesting at 20 years old. On the basis of the genetic correlations estimates from the environments, the clones' selection of Pinus taeda propagated via somatic embryogenesis should be developed specifically for each environment. The clones' selection can be performed considering the diameter due to the high correlation between volume and diameter.


Methodology ◽  
2018 ◽  
Vol 14 (4) ◽  
pp. 177-188 ◽  
Author(s):  
Martin Schultze ◽  
Michael Eid

Abstract. In the construction of scales intended for the use in cross-cultural studies, the selection of items needs to be guided not only by traditional criteria of item quality, but has to take information about the measurement invariance of the scale into account. We present an approach to automated item selection which depicts the process as a combinatorial optimization problem and aims at finding a scale which fulfils predefined target criteria – such as measurement invariance across cultures. The search for an optimal solution is performed using an adaptation of the [Formula: see text] Ant System algorithm. The approach is illustrated using an application to item selection for a personality scale assuming measurement invariance across multiple countries.


2016 ◽  
Vol 11 (3) ◽  
pp. 217
Author(s):  
Estu Nugroho ◽  
Budi Setyono ◽  
Mochammad Su’eb ◽  
Tri Heru Prihadi

Program pemuliaan ikan mas varietas Punten dilakukan dengan seleksi individu terhadap karakter bobot ikan. Pembentukan populasi dasar untuk kegiatan seleksi dilakukan dengan memijahkan secara massal induk ikan mas yang terdiri atas 20 induk betina dan 21 induk jantan yang dikoleksi dari daerah Punten, Kepanjen (delapan betina dan enam jantan), Kediri (tujuh betina dan 12 jantan), Sragen (27 betina dan 10 jantan), dan Blitar (15 betina dan 11 jantan). Larva umur 10 hari dipelihara selama empat bulan. Selanjutnya dilakukan penjarangan sebesar 50% dan benih dipelihara selama 14 bulan untuk dilakukan seleksi dengan panduan hasil sampling 250 ekor individu setiap populasi. Seleksi terhadap calon induk dilakukan saat umur 18 bulan pada populasi jantan dan betina secara terpisah dengan memilih berdasarkan 10% bobot ikan yang terbaik. Calon induk yang terseleksi kemudian dipelihara hingga matang gonad, kemudian dipilih sebanyak 150 pasang dan dipijahkan secara massal. Didapatkan respons positif dari hasil seleksi berdasarkan bobot ikan, yaitu 49,89 g atau 3,66% (populasi ikan jantan) dan 168,47 g atau 11,43% (populasi ikan betina). Nilai heritabilitas untuk bobot ikan adalah 0,238 (jantan) dan 0,505 (betina).Punten carp breeding programs were carried out by individual selection for body weight trait. The base population for selection activities were conducted by mass breeding of parent consisted of 20 female and 21 male collected from area Punten, eight female and six male (Kepanjen), seven female and 12 male (Kediri), 27 female and 10 male (Sragen), 15 female and 11 male (Blitar). Larvae 10 days old reared for four moths. Then after spacing out 50% of total harvest, the offspring reared for 14 months for selection activity based on the sampling of 250 individual each population. Selection of broodstock candidates performed since 18 months age on male and female populations separately by selecting based on 10% of fish with best body weight. Candidates selected broodstocks were then maintained until mature. In oder to produce the next generation 150 pairs were sets and held for mass spawning. The results revealed that selection response were positive, 49.89 g (3.66%) for male and 168.47 (11.43%) for female. Heritability for body weight is 0.238 (male) and 0.505 (female).


Confectionery sunflower - a special area of use of sunflower, which requires the creation of marketable seeds quality features. One of the possible ways to create large-fruited sunflower is to create production hybrids and lines. Objective: to evaluate the created new large-fruited sunflower lines by a complex of morphological characters and determine the best lines for use as large-seeds hybrids as parent components or source material. In 2016-2019 years on the basis of the Institute of Oilseed Crops NAAS a study was conducted to assess the economic characteristics of large-fruited sunflower lines. We studied a collection of 27 lines of large-seeds sources. The lines were created by direct selection or crossing and sampling: Reyny of Argentinean origin, Zaporizhzhya confectionery variety, confectionery hybrid with striped pericarp color of Israeli origin, white seed of Turkish origin, synthetic population - donor of complex resistance. To study from the collection, lines were drawn that went through at least 7 generations with selection for seed size. Experience has shown that the shortest growing season for lines 174d and KP11 was 99 days, and the longest for lines I2K670 was 109 days. In the studied collection, the greatest mass of 1000 seeds has the KP11-146.47g line, which is the mother component and does not have branching. The second by weight of 1000 seeds (109 g) stood out line 168v, which also had branches and pollen fertility restoration genes and will be used as the paternal form. The third largest is also one basket line ZKN51-100. The collection included lines originating from the same combination, but with a different morphotype for the presence and absence of branching. So, based on the combination of KP11 x Zaporizhzhya Confectionery, three lines were obtained. A mass of 1000 seeds was observed in 98-86 g, with the branching line having the largest mass of 1000 seeds. The lines created with one combination VK678 x ZKN32: with a branch 168a had a mass of 1000 seeds 95g, and a line 168b - without a branch 109 g. Of the two lines obtained from the descendants of the combination KP11 x the striped hybrid both had branches, but the seeds were much smaller (weight of 1000 seeds 59 and 79 g). The collection also studied samples created on the basis of varieties and populations 160c, 174, 175b, the mass of 1000 seeds of which turned out to be more acceptable for large-fruited use from 83 to 99 g. Summing up the results of studying the collection of newly created lines, we can highlight the lines 162d, 168v, 175b, KP11 that are potentially promising for use in hybrids. The selections showed that large-fruited lines can be obtained from large-fruited varieties, self-pollination of large-fruited hybrids and crossing lines with hybrids and varieties. Self-pollination and selection of large-fruited lines in several generations does not provide the necessary variability for positive changes in selections. The result of the selection by weight of 1000 seeds in the offspring from crosses and from populations creates opportunities for new large-seeds sunflower.


Glycobiology ◽  
2021 ◽  
Author(s):  
Hannah M Stephen ◽  
Trevor M Adams ◽  
Lance Wells

Abstract Thousands of nuclear and cytosolic proteins are modified with a single β-N-acetylglucosamine on serine and threonine residues in mammals, a modification termed O-GlcNAc. This modification is essential for normal development and plays important roles in virtually all intracellular processes. Additionally, O-GlcNAc is involved in many disease states, including cancer, diabetes, and X-linked intellectual disability. Given the myriad of functions of the O-GlcNAc modification, it is therefore somewhat surprising that O-GlcNAc cycling is mediated by only two enzymes: the O-GlcNAc transferase (OGT), which adds O-GlcNAc, and the O-GlcNAcase (OGA), which removes it. A significant outstanding question in the O-GlcNAc field is how do only two enzymes mediate such an abundant and dynamic modification. In this review, we explore the current understanding of mechanisms for substrate selection for the O-GlcNAc cycling enzymes. These mechanisms include direct substrate interaction with specific domains of OGT or OGA, selection of interactors via partner proteins, posttranslational modification of OGT or OGA, nutrient sensing, and localization alteration. Altogether, current research paints a picture of an exquisitely regulated and complex system by which OGT and OGA select substrates. We also make recommendations for future work, toward the goal of identifying interaction mechanisms for specific substrates that may be able to be exploited for various research and medical treatment goals.


2019 ◽  
Vol 87 ◽  
pp. 258-265 ◽  
Author(s):  
Rashmi Chhabra ◽  
Firoz Hossain ◽  
Vignesh Muthusamy ◽  
Aanchal Baveja ◽  
Brijesh Mehta ◽  
...  

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