Abuse of Laxatives to Reduce Weight

1988 ◽  
Vol 9 (7) ◽  
pp. 208-234
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Anorexia Nervosa ◽  
Bulimia Nervosa ◽  
Diagnostic Criteria ◽  
Normal Weight ◽  
Intense Fear ◽  
Maintain Body Weight ◽  
Psychiatric Conditions ◽  
Weight For Age

Two psychiatric conditions are commonly associated with laxative and/or diuretic abuse to control weight. They are anorexia nervosa and bulimia nervosa. The newest diagnostic criteria for anorexia nervosa now makes it possible to diagnose this disorder before profound weight loss has occurred. There are four criteria: (1) refusal to maintain body weight greater than a minimum normal weight for age and height, the minimum being 15% below that expected; (2) intense fear of gaining weight; (3) a disturbance in the way one's body weight, size, or shape is experienced; and (4) amenorrhea in girls. Anorexia nervosa usually begins in early to late adolescence. It is primarily a disorder of girls.

scholarly journals A clinical course of a patient with anorexia nervosa receiving surgery for superior mesenteric artery syndrome

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Ken Kurisu ◽  
Yukari Yamanaka ◽  
Tadahiro Yamazaki ◽  
Ryo Yoneda ◽  
Makoto Otani ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Anorexia Nervosa ◽  
Superior Mesenteric Artery ◽  
Mesenteric Artery ◽  
Rare Complication ◽  
Nutrition Therapy ◽  
Psychological Status ◽  
Sma Syndrome

Abstract Background Superior mesenteric artery (SMA) syndrome is a well-known but relatively rare complication of anorexia nervosa. Although several reports have proposed surgery for SMA syndrome associated with anorexia nervosa, these have shown poor outcomes or did not reveal the long-term weight course. Thus, the long-term effectiveness of surgery for SMA syndrome in such cases remains unclear. This case report describes a patient with anorexia nervosa who underwent surgery for SMA syndrome. Case presentation An 18-year-old woman presented with anorexia nervosa when she was 16 years old. She also presented with SMA syndrome, which seemed to be caused by weight loss due to the eating disorder. Nutrition therapy initially improved her body weight, but she ceased treatment. She reported that symptoms related to SMA syndrome had led to her weight loss and desired to undergo surgery. Laparoscopic duodenojejunostomy was performed, but her body weight did not improve after the surgery. The patient eventually received conservative nutritional treatment along with psychological approaches, which led to an improvement in her body weight. Conclusions The case implies that surgery for SMA syndrome in patients with anorexia nervosa is ineffective for long-term weight recovery and that conservative treatment can sufficiently improve body weight; this is consistent with the lack of evidence on the topic and reports on potential complications of surgery. Due to difficulties in assessing psychological status, consultation with specialists on eating disorders is necessary for treating patients with severely low body weight.

scholarly journals The value of blood serotonin for effective weight loss in obese women

2015 ◽  
Vol 12 (3) ◽  
pp. 31-35
Author(s):  
Natal'ya Vadimovna Anikina ◽  
Elena Nikolaevna Smirnova
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Clinical Laboratory ◽  
Normal Weight ◽  
Obese Patients ◽  
Obese Women ◽  
Endothelin 1 ◽  
Excessive Accumulation ◽  
Made In

Introduction. Obesity is a disorder of energy balance, which leads to excessive accumulation of fat. In recent years, many important discoveries were made in this field, including the discovery of hormones produced by adipose tissue and the identification of many of the central and peripheral pathways of energy balance.Objective. To study the levels of hormones that affect appetite and metabolism in women with obesity baseline and after weight loss while taking sibutramine.Materials and methods. The study included 56 women aged 42,9±9,5 years, with a BMI of 34,6±6,1 kg/m2. All patients underwent clinical, laboratory and instrumental examination. Hormonal study included determination of serotonin, leptin, ghrelin, endothelin-1, adiponectin.Results: In women with obesity we identified hyperleptinemia and increased serotonin levels. The decrease in body weight in patients receiving sibutramine was accompanied by lower levels of serotonin, leptin, ghrelin, endothelin-1, and increase of adiponectin.Conclusions: Obese patients have significantly elevated levels of leptin, serotonin, ghrelin compared to women of normal weight. Sibutramine treatment leads to a decrease in serotonin, leptin, ghrelin and is more effective in women with a BMI less than 36,5 kg/m2.

scholarly journals MON-161 Body Weight Reduction Not Always Reduced Adrenal Gland Volume in Obese Patients

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Tao Chen
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Sleeve Gastrectomy ◽  
Adrenal Gland ◽  
Morphological Changes ◽  
Normal Weight ◽  
Obese Patients ◽  
Gland Volume ◽  
Significant Difference ◽  
Adrenal Gland Volume

Abstract Recent studies have shown that obesity is a major risk factor for idiopathic hyperaldosteronism (IHA). IHA patients have greater AGV than normal controls. However, it is unclear whether such changes are caused by obesity and whether losing weight could reverse the morphological and functional abnormalities of the adrenal gland. This study was to investigate the association of obesity with adrenal gland volume (AGV) and the effects of weight loss on AGV. This study recruited obese patients (N=25) who underwent sleeve gastrectomy and age- and sex-matched normal-weight (N=25) and overweight healthy volunteers (HV) (N=21). Thin-slice computed tomography was used to evaluate adrenal morphological changes. AGV was measured semiautomatically based on the digital imaging and communications in medicine (DICOM) image. The effects of weight loss on AGV were evaluated in patients for one year or more after sleeve gastrectomy. The results showed that left, right and total AGV were larger in obese patients than those in overweight and normal- weight HVs (6.77±0.36, 5.76±0.31, and 12.53±0.64 cm3 vs. 3.88±0.14, 3.09± 0.13 and 6.97± 0.24 cm3 vs. 3.38±0.23, 2.67±0.15 and 6.04±0.36 cm3). No statistically significant difference was identified between overweight and normal-weight HVs. Sleeve gastrectomy significantly reduced body weight (-27.1±2.5 kg), left AGV (-0.80±0.26 cm3), and right AGV (-0.88±0.20 cm2). However, the adrenal volume in five patients was not reduced, despite significant weight loss postsurgery. In brief, obesity leads to increased AGV, and in some cases, this effect seems to be irreversible. We speculate that obesity causes permanently adrenal morphological changes (increased volume or hyperplasia), and under certain circumstances, it results in excessive aldosterone secretion via altered adipokines (leptin, CTRP1, etc.).

Setting the scene for eating disorders: childhood care, classification and course of illness

1993 ◽  
Vol 23 (3) ◽  
pp. 663-672 ◽  
Author(s):  
Ulrike Schmidt ◽  
Jane Tiller ◽  
Janet Treasure
Keyword(s):  
Anorexia Nervosa ◽  
Bulimia Nervosa ◽  
Family Environment ◽  
Parental Control ◽  
Childhood Adversity ◽  
Normal Weight ◽  
Semistructured Interview ◽  
Childhood Experiences ◽  
Course Of Illness ◽  
Childhood Care

SynopsisThe aim of this study was to determine whether the childhood experiences of patients with anorexia nervosa and bulimia nervosa differ and affect the course of the illness. A semistructured interview developed by Harris et al. (1986) was used to assess the childhood family environment of 64 patients with restricting anorexia nervosa (RAN), 23 patients with bulimic anorexia nervosa (BAN), 37 bulimic patients with a history of anorexia nervosa (BN/HistAN) and 79 patients with normal weight bulimia nervosa (BN).There were no significant differences between groups in terms of parental mental disorder, low parental control or childhood sexual abuse. BN patients had had significantly more family arrangements and had experienced more parental indifference, excessive parental control, physical abuse, and violence against other family members than RAN patients with the BAN and BN/HistAN group being intermediate. There was a trend for BN-patients to have had more intra-familial discord than the other groups. Different aspects of adversity tended to cluster in the same patients and 65% of the bulimic group had experienced two or more types of childhood adversity. These results suggest that childhood experiences contribute to the form of eating disorder which later develops.

Eating Disorders: Implications for the 1990's*

1987 ◽  
Vol 32 (7) ◽  
pp. 624-631 ◽  
Author(s):  
Paul E. Garfinkel ◽  
David M. Garner ◽  
David S. Goldbloom
Keyword(s):  
Eating Disorders ◽  
Anorexia Nervosa ◽  
Bulimia Nervosa ◽  
Treatment Strategies ◽  
Risk Groups ◽  
Normal Weight ◽  
Stepped Care ◽  
Endogenous Opiates ◽  
Populations At Risk ◽  
The Relationship

In the past decade much has been learned about the clinical features, diagnosis and understanding of people with anorexia nervosa and bulimia nervosa. In order to provide the next level of improvement in our care for these patients, our understanding of certain problems must be addressed by empirical research. Areas which require further study include the definition of high risk groups, the refinement of diagnoses, understanding factors which result in chronicity, determining the complications of chronicity and comparative evaluations of different treatments. These five areas are outlined in this article. Populations at risk for anorexia nervosa and bulimia nervosa may be those who must be thin and achieve according to career choice, those with a particular family and personal psychiatric history; obesity and chronic medical illnesses may be further risks. Improved diagnostic understanding has occurred by the differentiation of bulimic from restricting subtypes of anorexia nervosa. Further work must determine the relationship between the bulimic subtype of anorexia nervosa and bulimia in normal weight women and to further clarify the relationship between eating disorders and affective disorders. A number of factors may result in a chronic illness. These have been described on a variety of levels. The consequences of starvation in altering an individual's thinking, feeling and behaviour do play a role. It is not clear what factors at a neurochemical level contribute to this. Elevated endogenous opiates decreased noradrenergic function and decreased serotonin may be important. Information about the chronic complications is required for clinicians to understand the broad range of difficulties that may develop over time so that clinicians may use this information in planning treatment strategies. Two examples, those of osteoporosis and the pregnant woman with an eating disorder, highlight this problem. Finally, treatment is briefly reviewed in terms of options available and the idea of developing a stepped-care approach to treatment.

Effects of shelter, exposure and level of feeding over winter on the productivity of Welsh Mountain ewes and lambs

1973 ◽  
Vol 17 (1) ◽  
pp. 21-32 ◽  
Author(s):  
W. I. Robinson ◽  
W. Brown ◽  
I. A. M. Lucas
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Organic Matter ◽  
Live Weight ◽  
Outdoor Exposure ◽  
Wool Growth ◽  
Digestible Organic Matter ◽  
Maintain Body Weight ◽  
Fourth Experiment ◽  
Different Levels

SUMMARYPregnant Welsh Mountain ewes were kept over winter on a hill. All were penned individually, either in a shed or out of doors. In Experiments 1 and 2 different levels of digestible organic matter (DOM) were given in each environment and in Experiment 3 only a single level was offered. In Experiment 2 all ewes were grazed together after lambing; in Experiment 3 some from each treatment were moved to a shed after lambing and their milk yields recorded between 10 and 15 days later.In a fourth experiment on low land, pregnant ewes were either housed or kept in an exposed or a sheltered paddock. All were grazed together after lambing.The results indicated that the requirement of indoors penned sheep to maintain body weight and produce a single lamb is 9·5 g DOM/kg live weight per 24 hr at 16 weeks pre-partum, rising to 15·0 g DOM/kg live weight per 24 hr at 1 week pre-partum. A 10% weight loss during pregnancy would be expected in ewes receiving 75 to 80 % of these requirements. Low intakes during pregnancy reduced wool growth and lamb birth weights.Outdoor exposure reduced pre-partum ewe weight by about 1·5 kg, and so was equivalent to a 10% reduction in daily DOM intake. The magnitude of this effect was not changed significantly by level of feeding. Exposure did not affect wool growth and its influence on lamb birth weight and growth was variable.

Weight Loss Time as a Function of Constantly Maintained Percentage Body Weight

1966 ◽  
Vol 19 (3) ◽  
pp. 829-830 ◽  
Author(s):  
David Ehrenfreund
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Weight Control ◽  
Absolute Weight ◽  
White Rats ◽  
Maintain Body Weight ◽  
Control Devices

17 white rats were maintained in weight-control devices which continuously and automatically maintain body weight within 1%. Temporal distributions of weight loss times were aperiodic and failed to correlate with ad lib. or absolute weight.

Bulimia Nervosa in Hong Kong Chinese Patients

1992 ◽  
Vol 161 (4) ◽  
pp. 545-551 ◽  
Author(s):  
Sing Lee ◽  
L. K. George Hsu ◽  
Y. K. Wing
Keyword(s):  
Anorexia Nervosa ◽  
Hong Kong ◽  
Bulimia Nervosa ◽  
Binge Eating ◽  
Clinical Features ◽  
Normal Weight ◽  
Hong Kong Chinese ◽  
Chinese Patients ◽  
Case Histories ◽  
The West

In contrast to the West, bulimic disorders are rarer than anorexia nervosa in Hong Kong. Four female normal-weight bulimic patients with mostly typical clinical features and conspicuous morbidity are reported. The case histories support the hypothesis that binge-eating is used to regulate unpleasant affect.

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