scholarly journals Gyorsreagálás a pandémiára, ellátásbiztonság

2021 ◽  
Vol 2 (2) ◽  
pp. 172-176
Author(s):  
István Greiner
Keyword(s):  
Critical Period ◽  
Scale Up ◽  
Fatal Outcome ◽  
Final Conclusion ◽  
Huge Amount ◽  
Substantial Impact ◽  
The World ◽  
International Boundaries ◽  
Economical Process

Összefoglaló. A tavalyi évben kitört COVID–19 pandémia jelentős kihívások elé állította a világot. Nem pusztán a kormányok és az egészségügyi rendszerek szembesültek új, békeidőben eddig még nem gyakorolt feladatokkal, de a tudományos világnak is át kellett tekinteni mind a régi, mind a legmodernebb eszközöket ahhoz, hogy a vírus terjedésének, a betegek szenvedéseinek, a tömeges halálozásoknak végre véget lehessen vetni. Habár a járványnak még messze nincsen vége, és egyre újabb és újabb mutánsok ütik fel a fejüket a világ legkülönbözőbb részein, mégis azokat a tanulságokat, melyek már összegyűltek a gyógyszeripar területén, érdemes összefoglalni. Talán még ennél is fontosabb azonban, hogy azokat a hiányokat, amelyeket még be kell pótolni, szintén megemlítsük, hogy ezzel is segítsük az újabb hullámok vagy járványok leküzdését. Summary. During the last 12 months the most serious issue was the SARS-CoV-2 virus generated pandemia around the world. There is no country which could be more or less intact and a huge amount of resources was sacrificed to rescue people from the fatal outcome of this disease. When it started a year ago or more, there were doubts about its future but later it was realised that this is an epidemic occurring worldwide, crossing international boundaries, and affecting a large number of people. According to the WHO, today the number of confirmed cases is about 157.8 million, confirmed deaths are 3.3 million and 1.2 billion vaccine doses have been administered. These numbers clearly show how important it is to elaborate the reaction of the pharma industry and investigate how to ensure safe drug supply for patients in every country. The topics discussed below are the basic and unique features of the SARS-CoV-2 virus, the pandemia generated by it, and the role of the Hungarian pharma industry, especially Gedeon Richter plc, during this critical period. On one hand the author explains how the spread of virus can be decreased in general and at a production facility like Richter, and on the other hand R&D activity of the Company aiming to cure patients suffering from COVID-19 infection. Consortia including universities, academia and industrial entities made a substantial impact on handling this terrible epidemic. Gedeon Richter plc, the biggest and only independent Hungarian pharma company, in keeping with its roots started small molecule R&D to make favipiravir and remdesivir available to clinics. The latter production is a very difficult one but using its background in chemistry Richter was able to manage all R&D and industrial scale up activities in six months. Moreover, it has filed two patent applications about its new, more feasible and economical process steps justifying its innovative attitude. As a final conclusion it is stated that for the safe supply of necessary medication one critical step is missing from the capabilities of the Hungarian pharma industry, the vaccine R&D and production.

scholarly journals On the Role of Gesinnung in Kant’s Ethics and Philosophy of Religion. Part II

2019 ◽  
Vol 38 (4) ◽  
Author(s):  
Alexei N. Krouglov
Keyword(s):  
Practical Reason ◽  
Critical Period ◽  
Free Expression ◽  
Human Being ◽  
The Novel ◽  
The World ◽  
The Will ◽  
Kant's Ethics ◽  
The Revolution

The sources of Kant’s term Gesinnung and a review of the problems of its translation into English were presented in the first part of this article; the second part examines the novel features that Kant brings to the interpretation of this concept in the critical period. In the Critique of Practical Reason these include the questions of manifestation of Gesinnung in the world, apprehended through the senses, the method of establishing and the culture of truly moral Gesinnung, as well as the problem of the immutability of Gesinnung in the progress towards the good. The new theses that appear in Religion within the Bounds of Bare Reason are Gesinnung as the internal subjective principle of maxims, on virtue as evidence of the presence of Gesinnung, on act as a manifestation of Gesinnung, on the unintelligibility of Gesinnung in its noumenal, suprasensible character, on the innateness of Gesinnung in the sense that it exists not in time, but in the form of its acceptance by free expression of the will, on the singleness of Gesinnung and its indivisibility into periods, on revolution in Gesinnung as distinct from empirical reform, on the creation of the new human being as distinct from the ancient one as a result of the revolution of Gesinnung, on the link between the revolution in Gesinnung and “conversion” or second birth. After discussing the problem of distinguishing the terms Gesinnung and Denkungsart in translation as well as a review of all the existing variants of translating Kant’s concept of Gesinnung into Russian (aspiration, inclination, intention, virtue, virtuousness, conviction, attitude, mode of thinking, thoughts, mood, disposition and umonastroenie), the author comes to the conclusion that the uniform variant umonastroenie is best suited for Russian translations of Kant’s works.

The Overproduction of Truth

2018 ◽  
Author(s):  
Gianfranco Pacchioni
Keyword(s):  
Critical Review ◽  
Scientific Journals ◽  
Huge Amount ◽  
Scientific Publications ◽  
The Troubles ◽  
Contemporary Science ◽  
The World ◽  
Personal Reflections ◽  
Science Production

The way science is done has changed radically in the last years. The personal reflections and experiences of a protagonist help us to understand the mechanisms of contemporary science. A system where passion, dedication and reliability, have increasingly less room, pressed by hard market laws. From vocation of a few, science has become the profession of many, possibly too many. With consequences and risks, such as the increase of frauds, plagiarism, but in particular with a huge amount of scientific publications, often of little relevance. The solution? A slow approach with more emphasis to quality than quantity, that helps us to rediscover the central role of a responsible scientist. The work is a critical review and assessment of present-day policies and behaviors in science production and publication, touching upon the tumultuous growth of scientific Journals, in parallel to the growth of self-declared scientists over the world. Along with personal reminiscences of times past, the author investigates the loopholes and hoaxes of pretended Journals and non-existing Congresses, so common nowadays in the scientific arena. The troubles with bibliometric indices are also discussed, as resulting in large part from the above distortions of science life.

The ageing population

2021 ◽  
pp. 175573802199281
Author(s):  
Jenny Walton ◽  
Angus Kaye
Keyword(s):  
Primary Care ◽  
General Practice ◽  
Older People ◽  
Healthcare Professionals ◽  
Ageing Population ◽  
Huge Amount ◽  
Older Population ◽  
The World ◽  
The Individual

As we all age, the demographic of the world changes. Looking after older people well can bring a huge amount of pleasure and satisfaction, not just to the individual, but also to their family, friends and indeed healthcare professionals. How we care for our elderly now is likely to set a precedent for our own care in the future. This article highlights some of the features of ageing and discusses the role of primary care in the management of the older population, within the context of the general practice curriculum.

Het wereldparlement van religies te Chicago (1893)

2015 ◽  
Vol 69 (1) ◽  
pp. 1-20
Author(s):  
Arie L. Molendijk
Keyword(s):  
Religious Studies ◽  
Final Conclusion ◽  
Participation Of Women ◽  
The World ◽  
Mega Event ◽  
The Relationship ◽  
World Exhibition

The aim of this contribution is to give a coherent account of the World Parliament of Religions held in Chicago in 1893. The meeting was organised in the context of the Columbian World Exhibition, which celebrated 400 years of America. The Parliament convened in the main hall of the Chicago Art Institute and attracted 150,000 people, according to one of the lengthy reports. Various aspects are addressed: the objectives of the organisers, the character of the various reports of this mega-event, the participation of women, the relationship between the Christian organisers and the representatives of the East, the various ‐ opposing ‐ claims about the superiority of specific forms of religion and culture (for instance, the juxtaposition of the material West and the spiritual East), the tendency to spiritualize religion, and the role of the emerging field of religious studies versus the ‘interfaith’ character of the Parliament. It is hardly possible to draw one final conclusion from this heterogeneous event, but perhaps one can say that the participants were convinced of the ultimate meaning of ‘religion’ ‐ however defined ‐ as a force against indulging in consumerism and materialism.

scholarly journals Evaluation of technologies and resources from the spatial and social aspect

2014 ◽  
pp. 73-75
Author(s):  
János Nagy ◽  
Botond Sinóros-Szabó
Keyword(s):  
Positive Interactions ◽  
Final Conclusion ◽  
Social Aspect ◽  
The World ◽  
Negative Impacts ◽  
Thermodynamic Interpretation

The basic functioning of the world is mostly led by negative trends. One of the fundamental reasons for this phenomenon is that the different technologies (hardware, software, resources) do not act properly and in the proper structure by means of the produced products and services. Therefore, the examination of technologies and resources is a key question of our world and development from various aspects. Technologies convey all positive and negative impacts which can be regarded as the fundamental reasons and causes of harmonious or disharmonious development. For this reason, the role of technologies in development and harmonious functioning is of paramount importance. As a final conclusion, we established that the different technologies (hardware, software, resources) are interpreted as impact conveyors which predominate by means of products and services in a way that their relation system is determined. By using the thermodynamic interpretation which is the basis of the functioning of the world, we built a system consisting of 14 elements to evaluate different technologies, to interpret its functioning and to develop positive interactions and trends.

The role of early embryonic environment on epigenotype and phenotype

2005 ◽  
Vol 17 (3) ◽  
pp. 335 ◽  
Author(s):  
Nicola Vickaryous ◽  
Emma Whitelaw
Keyword(s):  
Environmental Conditions ◽  
Critical Period ◽  
Reproductive Technologies ◽  
Epigenetic Modifications ◽  
Early Embryogenesis ◽  
Specific Gene ◽  
Methylation State ◽  
The World ◽  
Adult Organism

The influence of epigenetic modifications to the genome on the phenotype of the adult organism is now a tractable problem in biology. This has come about through the development of methods that enable us to study the methylation state of the DNA and the packaging of the chromatin at specific gene loci. It is becoming clear that early embryogenesis is a critical period for the establishment of the epigenotype. Furthermore, it appears that this process is sensitive to environmental conditions. This is a concern in light of the increasing use of artificial reproductive technologies throughout the world.

scholarly journals Role of Microorganisms Like Bacteria and Fungi in Polythene Degradation

2021 ◽  
Vol 9 (9) ◽  
pp. 1072-1078
Author(s):  
Lekh Ram
Keyword(s):  
Adverse Effect ◽  
Review Paper ◽  
Degradation Process ◽  
Huge Amount ◽  
Future Needs ◽  
The World ◽  
Living Organisms ◽  
Bacteria And Fungi

Abstract: Polythene degradation is a challenge all over the world. It is a serious problem throughout the globe to reduce polythene garbage. Every year 500 billion to 1 trillion polythene carry bags are being consumed around the globe. It is a huge amount to be used across the globe. Its degradation process is very slow as compare to other wastes and takes many years to decompose. It also have adverse effect on the environment and living organisms. In this review paper we are trying to attract attention on polythene pollution, it’s possible methods to decrease the polythene level, its degradation process and future needs on polythene degradation. Keywords: Polythene, Degradation, Pollution, Waste.

scholarly journals PENERAPAN PERMAINAN EDUKATIF MEDIA BERGAMBAR

2020 ◽  
Vol 2 (2) ◽  
pp. 29
Author(s):  
Nunuk Setiyowati
Keyword(s):  
Growth And Development ◽  
Critical Period ◽  
Further Education ◽  
Full Potential ◽  
The World ◽  
New Ideas ◽  
Group A ◽  
Changing Times ◽  
The Times

Play is the world of children. In play there is pleasure and satisfaction without coercion oriented to the process rather than the end result. Piaget (1962), suggested that learning while playing and playing while learning is an activity that must be presented so that children have readiness to enter further education. Educative games of pictorial media have an important role in developing all aspects of children’s intelligence, because in educational play activities, pictorial games of children become active in moving and thinking so that new ideas and experiences that will be important for their growth and development will emerge. Group A children are one of the times when children have to get a lot of positive stimulation in learning to develop their full potential, imagination and intelligence aspects so that they develop optimally. At this time it is often called a critical period or a golden age that whill not be repeated again. So that the role of parent, teacher and the environment becomes the main pillar for children’s growht and development, so that children grow intro tough generations who excel and are ready to face every challenge and all the changing times.

The essence and causes of the spiritual and moral decline of mankind in the XX century

1998 ◽  
pp. 124-127
Author(s):  
V. Tolkachenko
Keyword(s):  
Well Being ◽  
Religious Institutions ◽  
Social Force ◽  
The World ◽  
Role Of Religion

One of the most important reasons for such a clearly distressed state of society was the decline of religion as a social force, the external manifestation of which is the weakening of religious institutions. "Religion," Baha'u'llah writes, "is the greatest of all means of establishing order in the world to the universal satisfaction of those who live in it." The weakening of the foundations of religion strengthened the ranks of ignoramuses, gave them impudence and arrogance. "I truly say that everything that belittles the supreme role of religion opens way for the revelry of maliciousness, inevitably leading to anarchy. " In another Tablet, He says: "Religion is a radiant light and an impregnable fortress that ensures the safety and well-being of the peoples of the world, for God-fearing induces man to adhere to the good and to reject all evil." Blink the light of religion, and chaos and distemper will set in, the radiance of justice, justice, tranquility and peace. "

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